[go: up one dir, main page]

AU2001283563A1 - Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent - Google Patents

Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent

Info

Publication number
AU2001283563A1
AU2001283563A1 AU2001283563A AU8356301A AU2001283563A1 AU 2001283563 A1 AU2001283563 A1 AU 2001283563A1 AU 2001283563 A AU2001283563 A AU 2001283563A AU 8356301 A AU8356301 A AU 8356301A AU 2001283563 A1 AU2001283563 A1 AU 2001283563A1
Authority
AU
Australia
Prior art keywords
dosage forms
pharmaceutical dosage
oral pharmaceutical
antiarrhythmic agent
pulsatile delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001283563A
Inventor
Mark Hirsh
Whe-Yong Lo
Kamal K. Midha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierce Management LLC
Original Assignee
PEIRCE MAN LLC
Pierce Management LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PEIRCE MAN LLC, Pierce Management LLC filed Critical PEIRCE MAN LLC
Publication of AU2001283563A1 publication Critical patent/AU2001283563A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001283563A 2000-08-14 2001-08-14 Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent Abandoned AU2001283563A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09639584 2000-08-14
US09/639,584 US6500457B1 (en) 2000-08-14 2000-08-14 Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent
PCT/US2001/041712 WO2002013794A1 (en) 2000-08-14 2001-08-14 Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent

Publications (1)

Publication Number Publication Date
AU2001283563A1 true AU2001283563A1 (en) 2002-02-25

Family

ID=24564715

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001283563A Abandoned AU2001283563A1 (en) 2000-08-14 2001-08-14 Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent

Country Status (4)

Country Link
US (2) US6500457B1 (en)
EP (1) EP1311247A4 (en)
AU (1) AU2001283563A1 (en)
WO (1) WO2002013794A1 (en)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
IT1318625B1 (en) * 2000-07-14 2003-08-27 Roberto Valducci ORAL SOLID PHARMACEUTICAL FORMULATIONS WITH MULTI-PHASE RELEASE - EMPLOYEE.
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
SE0101329D0 (en) * 2001-04-12 2001-04-12 Astrazeneca Ab Pharmaceutical formulation
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
EP1396263A1 (en) * 2002-08-09 2004-03-10 Warner-Lambert Company Film coating for tablets and caplets
MY148805A (en) * 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
JP5586123B2 (en) * 2003-04-07 2014-09-10 スパーナス ファーマシューティカルズ インコーポレイテッド Tetracycline once a day formulation
EP2112920B1 (en) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US20050220873A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
US20060105044A1 (en) * 2004-05-20 2006-05-18 Singh Bramah N Sustained release formulations of sotalol
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
PL204079B1 (en) * 2004-08-12 2009-12-31 Inst Farmaceutyczny Oral solid tamsulozine hydrochloride preparation with prolonged release and method for its manufacture
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US20060165789A1 (en) * 2004-09-09 2006-07-27 Forest Laboratories, Inc. Lercanidipine modified release compositions
US20060165788A1 (en) * 2004-09-09 2006-07-27 Wattanaporn Abramowitz Lercanidipine pH dependent pulsatile release compositions
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
TW200626185A (en) * 2004-12-17 2006-08-01 Bpsi Holdings Inc Enteric film coating composition containing entericpolymer micronized with detackifier
MX2007012220A (en) * 2005-04-06 2007-12-06 Mallinckrodt Inc Matrix-based pulse release pharmaceutical formulation.
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
AU2013273835B2 (en) * 2005-05-02 2016-07-07 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
EP1896002A4 (en) 2005-06-27 2009-11-25 Biovail Lab Int Srl FORMULATIONS WITH MODIFIED RELEASE OF A BUPROPION SALT
WO2007030477A2 (en) * 2005-09-06 2007-03-15 Theraject, Inc. Solid solution perforator containing drug particle and/or drug-adsorbed particles
EP1954257A4 (en) * 2005-10-14 2009-05-20 Lundbeck & Co As H METHODS OF TREATING CENTRAL NERVOUS SYSTEM DISORDERS WITH LOW ESCITALOPRAM AND BUPROPION DOSE COMBINATION
US20070112075A1 (en) * 2005-10-14 2007-05-17 Forest Laboratories, Inc. Stable pharmaceutical formulations containing escitalopram and bupropion
US10064828B1 (en) * 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
KR20140088230A (en) * 2006-01-27 2014-07-09 앱탈리스 파마테크, 인코포레이티드 Drug delivery systems comprising weakly basic drugs and organic acids
AU2007211091B8 (en) * 2006-01-27 2013-08-29 Adare Pharmaceuticals, Inc. Drug delivery systems comprising weakly basic selective serotonin 5-HT3 blocking agent and organic acids
WO2007112581A1 (en) 2006-04-03 2007-10-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
EP2192892A2 (en) * 2007-07-27 2010-06-09 Depomed, Inc. Pulsatile gastric retentive dosage forms
TW200940110A (en) * 2008-02-22 2009-10-01 Astrazeneca Ab Pharmaceutical formulation comprising oxabispidines
US8133506B2 (en) * 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
US20090253801A1 (en) * 2008-04-07 2009-10-08 Shah Manish J Novel Antiarrhythmic Drug Formulations
FR2930147B1 (en) * 2008-04-18 2013-02-08 Flamel Tech Sa SOLID ORAL FORM WITH A DOUBLE RELEASE PROFILE
US8343524B2 (en) 2008-07-31 2013-01-01 Clarke Mosquito Control Products, Inc. Extended release tablet and method for making and using same
JP5698683B2 (en) 2009-03-09 2015-04-08 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ Pulsed release composition of therapeutic agent
US20110003005A1 (en) * 2009-07-06 2011-01-06 Gopi Venkatesh Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
CN102958515A (en) 2009-12-02 2013-03-06 阿普塔利斯制药有限公司 Fexofenadine microcapsules and compositions containing them
AU2013224598B2 (en) 2012-02-22 2015-09-17 Duchesnay Inc. Formulation of doxylamine and pyridoxine and/or metabolites or salts thereof
US9636305B2 (en) * 2013-03-14 2017-05-02 Redhill Biopharma Ltd. Antiemetic extended release solid dosage forms
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
UA116648C2 (en) 2013-03-14 2018-04-25 Алкермес Фарма Айерленд Лімітед FUMARATS AS A PRODUCT AND THEIR USE IN THE TREATMENT OF DIFFERENT DISEASES
EA029690B1 (en) 2013-07-22 2018-04-30 Дюшене Инк. Composition for the management of nausea and vomiting
US9604922B2 (en) 2014-02-24 2017-03-28 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
JP6461186B2 (en) 2014-03-11 2019-01-30 レッド ヒル バイオファーマ リミテッドＲｅｄＨｉｌｌ Ｂｉｏｐｈａｒｍａ Ｌｔｄ． Ondansetron sustained-release solid formulation for treating symptoms of nausea, vomiting or diarrhea
WO2016044704A1 (en) 2014-09-19 2016-03-24 The Procter & Gamble Company Pulsed release phenylephrine dosage forms
WO2016077832A2 (en) 2014-11-14 2016-05-19 Gemphire Therapeutics Inc. PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS
WO2017058869A1 (en) 2015-09-29 2017-04-06 Acorda Therapeutics, Inc. Sustained release compositions of 4-aminopyridine
US10278930B2 (en) 2017-03-16 2019-05-07 The Procter & Gamble Company Method for relieving sinus congestion
TW201906599A (en) * 2017-05-11 2019-02-16 美商珍費爾醫療公司 Gikabin composition and method of use thereof
CN109419779B (en) * 2017-09-04 2021-05-25 鲁南制药集团股份有限公司 Sotalol hydrochloride preparation
US10888524B2 (en) * 2018-02-05 2021-01-12 Enaltec Pharma Research Pvt. Ltd. Immediate release tablet of dofetilide
US11344518B2 (en) 2018-08-14 2022-05-31 AltaThera Pharmaceuticals LLC Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame
US12396970B2 (en) 2021-08-20 2025-08-26 AltaThera Pharmaceuticals LLC Anti-arrhythmic compositions and methods
US11696902B2 (en) 2018-08-14 2023-07-11 AltaThera Pharmaceuticals, LLC Method of initiating and escalating sotalol hydrochloride dosing
US10512620B1 (en) 2018-08-14 2019-12-24 AltaThera Pharmaceuticals, LLC Method of initiating and escalating sotalol hydrochloride dosing
US11610660B1 (en) 2021-08-20 2023-03-21 AltaThera Pharmaceuticals LLC Antiarrhythmic drug dosing methods, medical devices, and systems
CN113784711A (en) * 2019-03-12 2021-12-10 伊登布里奇制药有限公司 Orally disintegrating tablet containing glycopyrronium bromide and method for improving bioavailability
KR20220113941A (en) * 2019-12-11 2022-08-17 에보닉 오퍼레이션스 게엠베하 Dosage forms for use in treating or preventing a disease
EP4072532B1 (en) * 2019-12-11 2024-01-24 Evonik Operations GmbH Dosage form for use in treating or preventing of a disease
WO2021125824A1 (en) * 2019-12-19 2021-06-24 (주)셀트리온 Pharmaceutical formulation comprising cibenzoline or salt thereof
JP2023553274A (en) * 2020-11-18 2023-12-21 エフビー－エイチアールエス リミテッド ライアビリティ カンパニー Compositions containing dofetilide and mexiletine and uses thereof

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308126D0 (en) 1983-03-24 1983-05-05 Bloch M Pharmaceutical compositions
US5089526A (en) 1983-05-23 1992-02-18 Bristol-Myers Company Antiarrhythmic class III process
GB8319766D0 (en) 1983-07-22 1983-08-24 Graham N B Controlled release device
US4777049A (en) 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
US4794111A (en) 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
US4863744A (en) 1984-09-17 1989-09-05 Alza Corporation Intestine drug delivery
JPH0778017B2 (en) 1985-12-28 1995-08-23 住友製薬株式会社 Pulsed and sustained release formulation
DE3612212A1 (en) 1986-04-11 1987-10-15 Basf Ag METHOD FOR PRODUCING SOLID PHARMACEUTICAL FORMS
US5110597A (en) 1987-06-25 1992-05-05 Alza Corporation Multi-unit delivery system
EP0406315B1 (en) * 1988-03-24 1992-11-11 Bukh Meditec A/S Controlled release composition
US5387419A (en) 1988-03-31 1995-02-07 The University Of Michigan System for controlled release of antiarrhythmic agents
DK469989D0 (en) 1989-09-22 1989-09-22 Bukh Meditec PHARMACEUTICAL PREPARATION
US5017381A (en) 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system
US5226902A (en) 1991-07-30 1993-07-13 University Of Utah Pulsatile drug delivery device using stimuli sensitive hydrogel
DE69222006T2 (en) 1991-10-30 1998-01-22 Glaxo Group Ltd Multilayer compositions containing histamine or serotonin antagonists
US5209746A (en) 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5456679A (en) 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5260068A (en) 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system
US5260069A (en) 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
PT621032E (en) 1993-04-23 2001-01-31 Novartis Ag FARMACO CONTROLLED LIBERATION DISTRIBUTION DEVICE
US5618860A (en) 1993-05-19 1997-04-08 Ameron International Corporation Epoxy polysiloxane coating and flooring compositions
JPH07223970A (en) 1994-02-10 1995-08-22 Tanabe Seiyaku Co Ltd Release product in place in digestive tract
AUPM897594A0 (en) 1994-10-25 1994-11-17 Daratech Pty Ltd Controlled release container
US5874475A (en) 1995-12-21 1999-02-23 Pharmacia & Upjohn Company Antiarrhythmic (S)-enantiomers of methanesulfonamides
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
SK18097A3 (en) 1996-02-28 1997-10-08 American Cyanamid Co Substituted omega £phenoxy, phenylthio, phenylsulfinyl, phenylsulfonyl| £alkyl, alkenyl or alkinyl|amino carboxamides, sulfonamides and phosphonyl amides, pharmaceutical preparation containing them, process for producing them and their use
US5969017A (en) 1996-10-31 1999-10-19 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
ATE271379T1 (en) * 1996-11-06 2004-08-15 Wockhardt Europ Ltd SYSTEM FOR THE DELAYED RELEASE OF ACID LABEL SUBSTANCES
US5914134A (en) 1997-01-27 1999-06-22 Wockhardt Europe Limited Process for the pulsatile delivery of diltiazem HCL and product produced thereby
DE19710213A1 (en) 1997-03-12 1998-09-17 Basf Ag Process for the manufacture of solid combination dosage forms
US6046177A (en) * 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
US5840329A (en) 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system
US6083991A (en) 1997-06-04 2000-07-04 University Of Florida Research Foundation, Inc. Anti-arrhythmic composition and methods of treatment
US20010055613A1 (en) * 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
HU230454B1 (en) * 1998-11-02 2016-07-28 Alkermes Pharma Ireland Limited Multiparticulate modified release composition of methylphenidate
US6627223B2 (en) * 2000-02-11 2003-09-30 Eurand Pharmaceuticals Ltd. Timed pulsatile drug delivery systems

Also Published As

Publication number Publication date
US20020098232A1 (en) 2002-07-25
EP1311247A4 (en) 2006-05-10
EP1311247A1 (en) 2003-05-21
US6500457B1 (en) 2002-12-31
WO2002013794A1 (en) 2002-02-21
US6645524B2 (en) 2003-11-11

Similar Documents

Publication Publication Date Title
AU2001283563A1 (en) Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent
AU4334700A (en) Pharmaceutical dosage form for pulsatile delivery of methylphenidate
HUP0302319A3 (en) Pharmaceutical composition for oral administration of active ingredient
PL356358A1 (en) Solid dosage form of someticone for oral administration
AU2002216701A1 (en) Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
AU2513900A (en) Drug dosage unit for buccal administration of steroidal active agents
AU2002357012A1 (en) Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof
MXPA03006476A (en) Pharmaceutical dosage forms of epothilones for oral administration.
AU2879100A (en) Formulation and system for intra-oral delivery of pharmaceutical agents
IL161214A0 (en) Compositions for delivery of drug combinations
EP1455697A4 (en) Vaginal delivery of drugs
MXPA02003596A (en) Novel pharmaceutical compositions of anti-tubercular drugs and process for their preparation.
EP1246608A4 (en) Pharmaceutical formulations for the delivery of drugs having low aqueous solubility
IL149186A0 (en) Pharmaceutical compositions providing enhanced drug concentrations
AU2623600A (en) Compact dosage unit for buccal administration of a pharmacologically active agent
AU2001226029A1 (en) Pharmaceutical formulation and method for pulmonary and oral delivery
AU2001234114A1 (en) Drugs containing combined active ingredients
IL145559A0 (en) Tolperison-containing pharmaceutical preparation for oral administration
AU2001238346A1 (en) Modification of biopolymers for improved drug delivery
AU2001258395A1 (en) Formulations containing a glucocorticoid drug for the treatment of bronchopulmonary diseases
IL162385A (en) Benzothiazole - and benzoxazole - 4,7 - dione derivatives, uses thereof for the preparation of a medicament, medicaments containing them and pharmaceutical compositions containing them
AU3945501A (en) Apparatus for dosage of medicaments
AU5072000A (en) Pharmaceutical composition for nasally administering water-soluble active substances
AU2001260089A1 (en) Pharmaceutical compositions comprising desglymidodrine as an active drug substance
IL155855A0 (en) Pharmaceutical formulation of gepirone for oral administration