[go: up one dir, main page]

AU2001273461A1 - Methods for recombinatorial nucleic acid synthesis - Google Patents

Methods for recombinatorial nucleic acid synthesis

Info

Publication number
AU2001273461A1
AU2001273461A1 AU2001273461A AU7346101A AU2001273461A1 AU 2001273461 A1 AU2001273461 A1 AU 2001273461A1 AU 2001273461 A AU2001273461 A AU 2001273461A AU 7346101 A AU7346101 A AU 7346101A AU 2001273461 A1 AU2001273461 A1 AU 2001273461A1
Authority
AU
Australia
Prior art keywords
recombinatorial
methods
nucleic acid
acid synthesis
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273461A
Inventor
Andrew D. Ellington
George L. Murphy
Robert A Setterquist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ambion Inc
Original Assignee
Ambion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambion Inc filed Critical Ambion Inc
Publication of AU2001273461A1 publication Critical patent/AU2001273461A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2001273461A 2000-07-10 2001-07-10 Methods for recombinatorial nucleic acid synthesis Abandoned AU2001273461A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/613,535 US6994963B1 (en) 2000-07-10 2000-07-10 Methods for recombinatorial nucleic acid synthesis
US09/613,535 2000-07-10
PCT/US2001/022195 WO2002004630A2 (en) 2000-07-10 2001-07-10 Methods for recombinatorial nucleic acid synthesis

Publications (1)

Publication Number Publication Date
AU2001273461A1 true AU2001273461A1 (en) 2002-01-21

Family

ID=24457683

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273461A Abandoned AU2001273461A1 (en) 2000-07-10 2001-07-10 Methods for recombinatorial nucleic acid synthesis

Country Status (3)

Country Link
US (1) US6994963B1 (en)
AU (1) AU2001273461A1 (en)
WO (1) WO2002004630A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7332308B1 (en) * 1999-05-21 2008-02-19 The Penn State Research Foundation Incrementally truncated nucleic acids and methods of making same
US7871799B2 (en) * 2002-11-22 2011-01-18 Lawrence Livermore National Security, Llc Sequential addition of short DNA oligos in DNA-polymerase-based synthesis reactions
TWI333977B (en) * 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
US7501254B2 (en) * 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
ATE521704T1 (en) * 2007-03-01 2011-09-15 Symphogen As METHOD FOR CLONING RELATED ANTIBODIES
KR20110058861A (en) * 2008-08-29 2011-06-01 심포젠 에이/에스 Cloning Method of Algae-Derived Antibodies
DK3211126T3 (en) 2009-02-13 2020-12-21 X Chem Inc METHODS FOR FORMING AND SCREENING DNA-CODED LIBRARIES
MX360438B (en) 2011-09-07 2018-11-01 X Chem Inc Methods for tagging dna-encoded libraries.
EP2872680B1 (en) 2012-07-13 2018-04-04 X-Chem, Inc. Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
EP3673064A4 (en) * 2017-08-24 2021-05-26 Takara Bio USA, Inc. PROCESSES FOR THE PRODUCTION OF NUCLEIC ACIDS USING STIMULUS-MODIFIED OLIGONUCLEOTIDES

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59161398A (en) * 1983-03-02 1984-09-12 Mitsui Toatsu Chem Inc Method and apparatus for incising deoxyribonucleic acid
DE3546806C2 (en) 1985-03-30 1991-03-28 Marc Genf/Geneve Ch Ballivet
US4865968A (en) * 1985-04-01 1989-09-12 The Salk Institute For Biological Studies DNA sequencing
US5674679A (en) * 1991-09-27 1997-10-07 Amersham Life Science, Inc. DNA cycle sequencing
GB9208733D0 (en) * 1992-04-22 1992-06-10 Medical Res Council Dna sequencing method
ES2104160T3 (en) * 1992-07-31 1997-10-01 Behringwerke Ag METHOD FOR INTRODUCING DEFINED SEQUENCES AT THE 3 'END OF POLYNUCLEOTIDES.
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6165793A (en) 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
CN1123328A (en) * 1994-11-17 1996-05-29 中国科学院上海生物化学研究所 High-temperature, high-fidelity deoxyribonucleic acid (DNA) polymerase (HiFi Bst)
US5830655A (en) * 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
JPH1066576A (en) 1996-08-07 1998-03-10 Novo Nordisk As Double-stranded dna having protruding terminal and shuffling method using the same
GB9701425D0 (en) 1997-01-24 1997-03-12 Bioinvent Int Ab A method for in vitro molecular evolution of protein function
NZ337910A (en) 1997-03-18 2001-10-26 Novo Nordisk As Shuffling of heterologous DNA sequences using conserved regions
US6159687A (en) 1997-03-18 2000-12-12 Novo Nordisk A/S Methods for generating recombined polynucleotides
AU6611498A (en) 1997-03-18 1998-10-12 Novo Nordisk A/S Method for constructing a library using dna shuffling
EP0973940B1 (en) 1997-03-18 2008-07-02 Novozymes A/S An in vitro method for the construction of a dna library
US6153410A (en) 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
GB9712512D0 (en) 1997-06-16 1997-08-20 Bioinvent Int Ab A method for in vitro molecular evolution of protein function
DE19741714C2 (en) 1997-09-22 2002-03-21 Inst Molekulare Biotechnologie Process for the synthesis and amplification of nucleic acids
WO1999020768A1 (en) 1997-10-17 1999-04-29 The Procter & Gamble Company Methods for producing amylase enzymes
AR017831A1 (en) 1997-12-10 2001-10-24 Pioneer Hi Bred Int METHOD FOR ALTERING THE COMPOSITION OF AMINO ACIDS OF A NATIVE PROTEIN OF INTEREST, PREPARED PROTEIN, AND POLINUCLEOTIDE
DE19812103A1 (en) 1998-03-19 1999-09-23 Bernauer Annette Iteratively synthesizing nucleic acid from oligonucleotides which contain cleavable sites, useful for preparation of genes, ribozymes etc.
FR2782323B1 (en) * 1998-08-12 2002-01-11 Proteus PROCESS FOR THE IN VITRO PRODUCTION OF RECOMBINANT POLYNUCLEOTIDE SEQUENCES, SEQUENCE BANKS AND SEQUENCES THUS OBTAINED
WO2000042560A2 (en) 1999-01-19 2000-07-20 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides
US6534292B1 (en) * 2000-05-08 2003-03-18 Genencor International, Inc. Methods for forming recombined nucleic acids

Also Published As

Publication number Publication date
WO2002004630A2 (en) 2002-01-17
US6994963B1 (en) 2006-02-07
WO2002004630A3 (en) 2002-08-29

Similar Documents

Publication Publication Date Title
AU2002357049A1 (en) Methods for preparing 0-desmethylvenlafaxine
AU2002322518A1 (en) Methods for preparing nucleic acid samples
AU2001280815A1 (en) Intellectual property investment process
AU2001252588A1 (en) Method for preparing microsphere
AU2001254743A1 (en) Method for modifying acid group containing polymers
AU2003286588A1 (en) Methods for synthesizing complementary dna
IL149446A0 (en) Method for synthesizing nucleic acid
AU2001241590A1 (en) Process for redistribution of polycarbonate
AU2001233034A1 (en) Method for preparing alpha-sulfonyl hydroxamic acid derivatives
AU2001280167A1 (en) Novel propenohydroxamic acid derivatives
AU2001227086A1 (en) Process for preparing 2-hydroxy-4-methylthiobutanoic acid
AU2001273461A1 (en) Methods for recombinatorial nucleic acid synthesis
AU2001273762A1 (en) Process for the preparation of (r)-2-alkyl-3-phenyl-1-propanols
AU2001261476A1 (en) Nucleic acid sequences for novel gpcrs
AU1738201A (en) Adjuvants for nucleic acid vaccines
AU2001281827A1 (en) Method for producing 5-aminosalicyclic acid
AU7445100A (en) Sebum production inhibitors
AU2001232158A1 (en) Crystallizing process
AU2002217893A1 (en) Universal supports for oligonucleotide synthesis
AU2001213451A1 (en) Method for preparation of polycarbonates
AU2001249170A1 (en) Method for modifying a nucleic acid
AU2001240656A1 (en) System for producing steel
AU2001252390A1 (en) Nucleic acid immunization
AU2002237704A1 (en) Methods for the stereoselective synthesis of substituted piperidines
AU2003224265A1 (en) Nucleic acid immunization