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AU2001271989A1 - Asymmetric synthetic methods based on phase transfer catalysis - Google Patents

Asymmetric synthetic methods based on phase transfer catalysis

Info

Publication number
AU2001271989A1
AU2001271989A1 AU2001271989A AU7198901A AU2001271989A1 AU 2001271989 A1 AU2001271989 A1 AU 2001271989A1 AU 2001271989 A AU2001271989 A AU 2001271989A AU 7198901 A AU7198901 A AU 7198901A AU 2001271989 A1 AU2001271989 A1 AU 2001271989A1
Authority
AU
Australia
Prior art keywords
synthetic methods
phase transfer
methods based
transfer catalysis
asymmetric synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001271989A
Other languages
English (en)
Inventor
Christine Hofstetter
Thomas C. Pochapsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brandeis University
Original Assignee
Brandeis University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brandeis University filed Critical Brandeis University
Publication of AU2001271989A1 publication Critical patent/AU2001271989A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
    • B01J31/0235—Nitrogen containing compounds
    • B01J31/0239—Quaternary ammonium compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
    • B01J31/0235—Nitrogen containing compounds
    • B01J31/0244—Nitrogen containing compounds with nitrogen contained as ring member in aromatic compounds or moieties, e.g. pyridine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/643—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of R2C=O or R2C=NR (R= C, H)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/90—Catalytic systems characterized by the solvent or solvent system used
    • B01J2531/98—Phase-transfer catalysis in a mixed solvent system containing at least 2 immiscible solvents or solvent phases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU2001271989A 2000-07-13 2001-07-11 Asymmetric synthetic methods based on phase transfer catalysis Abandoned AU2001271989A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21790400P 2000-07-13 2000-07-13
US60217904 2000-07-13
US09/902,446 US6596870B2 (en) 2000-07-13 2001-07-10 Asymmetric synthetic methods based on phase transfer catalysis
US09902446 2001-07-10
PCT/US2001/021924 WO2002005953A2 (fr) 2000-07-13 2001-07-11 Procedes de synthese reposant sur la catalyse par transfert de phase

Publications (1)

Publication Number Publication Date
AU2001271989A1 true AU2001271989A1 (en) 2002-01-30

Family

ID=26912368

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001271989A Abandoned AU2001271989A1 (en) 2000-07-13 2001-07-11 Asymmetric synthetic methods based on phase transfer catalysis

Country Status (3)

Country Link
US (1) US6596870B2 (fr)
AU (1) AU2001271989A1 (fr)
WO (1) WO2002005953A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030057223A (ko) * 2001-12-28 2003-07-04 주식회사 티지 바이오텍 퀴놀린 알카로이드 유도체 및 이를 포함하는 약제 조성물
US6846946B2 (en) * 2002-02-15 2005-01-25 Value Recovery, Inc. Process for making organic products and improving the quality of non-product streams using phase transfer catalysis
US8765955B2 (en) 2004-06-03 2014-07-01 Brandeis University Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts
EP1758899A1 (fr) * 2004-06-03 2007-03-07 Brandeis University Additions asymetriques de michael et d'aldol utilisant des catalyseurs bifonctionnels a base de cinchonine
US7582764B2 (en) 2004-06-03 2009-09-01 Brandeis University Asymmetric carbon-carbon-bond-forming reactions catalyzed by bifunctional cinchona alkaloids
JP2008545704A (ja) * 2005-05-27 2008-12-18 ブランデイス ユニヴァーシティー 二官能性シンコナアルカロイドにより触媒作用が及ぼされる非対照炭素−炭素結合形成反応
US8791262B2 (en) 2005-12-02 2014-07-29 Brandeis University Asymmetric friedel-crafts alkylations catalyzed by bifunctional cinchona alkaloids
WO2013138413A1 (fr) * 2012-03-14 2013-09-19 Merck Sharp & Dohme Corp. Sels alcaloïdes bis-quaternaires de quinquina à titre de catalyseurs par transfert de phase asymétrique
CN102850153B (zh) * 2012-07-27 2014-11-05 四川大学 一种催化α,β-不饱和烯酮及饱和酮的不对称还原反应方法
SI3180336T1 (sl) * 2014-08-11 2019-01-31 Syngenta Participations Ag Postopek priprave optično aktivnih spojin izoksazolina

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175306A (en) 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
US4605761A (en) 1985-12-06 1986-08-12 Merck & Co., Inc. Process using achiral co-catalyst promoter for chiral phase transfer alkylation process for an enantiomer of a substituted fluorenyloxyacetic acid
US5126494A (en) 1988-01-11 1992-06-30 Massachusetts Institute Of Technology Methods for catalytic asymmetric dihydroxylation of olefins
US5260461A (en) 1988-01-11 1993-11-09 Massachusetts Institute Of Technology Ligands for ADH: cinchona alkaloids and moderately sized organic substituents linked through a planar aromatic spacer group
US5516929A (en) 1988-01-11 1996-05-14 Massachusetts Institute Of Technology Method for catalytic asymmetric dihydroxylation of olefins using heterocyclic chiral ligands
US5227543A (en) 1988-01-11 1993-07-13 Massachusetts Institute Of Technology Facilitation of turnover in the ADH by additives which catalyze the hydrolysis of the OS(VI) glycolate esters
US5840915A (en) 1990-01-22 1998-11-24 Hoechst Marion Roussel, Inc. Process for the enatioselective synthesis of intermediates used
DK0438796T3 (da) 1990-01-22 1999-05-25 Hoechst Marion Roussel Inc Fremgangsmåde til enantioselektiv syntese af alkylerede oxindoler, som anvendes som mellemprodukter ved fremstilling af phy
US5521320A (en) 1990-01-22 1996-05-28 Hoechst-Roussel Pharmaceuticals Incorporated Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
EP0480061B1 (fr) 1990-04-26 1996-12-04 Senju Pharmaceutical Co., Ltd. Inhibiteur de troubles hepatiques
IT1260506B (it) 1992-06-01 1996-04-09 Stefano Maiorana Processo per la preparazione di eseretolo
JPH06271514A (ja) 1993-01-21 1994-09-27 Sumitomo Chem Co Ltd 光学活性アミノアルコールの４級アンモニウム塩
JPH06271522A (ja) 1993-01-21 1994-09-27 Sumitomo Chem Co Ltd 光学活性シアノヒドリンエステルの製造方法
JPH0770121A (ja) 1993-06-22 1995-03-14 Sumitomo Chem Co Ltd 光学活性４級アンモニウム塩
US5554753A (en) 1993-08-25 1996-09-10 Indiana University Foundation Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis
US5576459A (en) 1994-02-02 1996-11-19 Sachem, Inc. Quaternary nitrogen or phosphorus chirates
US5488131A (en) 1994-03-23 1996-01-30 California Institute Of Technology Synthesis of compounds with predetermined chirality
US5767304A (en) 1996-05-21 1998-06-16 The Scripps Research Institute Catalytic asymmetric aminohydroxylation of olefins with carbamates
US5859281A (en) 1996-05-21 1999-01-12 The Scripps Research Institute Catalytic asymmetric aminohydroxylation of olefins with sulfonamides
US5994583A (en) 1996-05-22 1999-11-30 The Scripps Research Institute Two step synthesis of D- and L- α-amino acids and D- and L- α-amino-aldehydes
HU220961B1 (hu) 1996-11-18 2002-07-29 AGRO-CHEMIE Növényvédőszer Gyártó, Értékesítő és Forgalmazó Kft. Eljárás benzil-éterek előállítására fázistranszferrel
IT1298267B1 (it) 1998-02-18 1999-12-20 Zambon Spa Procedimento per la preparazione dell'acido (s)-2-acetiltio-3-fenil- propionico e dei suoi sali
AU3637699A (en) 1998-04-24 1999-11-16 Gilead Sciences, Inc. Preparation of carbocyclic compounds

Also Published As

Publication number Publication date
US20020115896A1 (en) 2002-08-22
WO2002005953A3 (fr) 2002-05-30
US6596870B2 (en) 2003-07-22
WO2002005953A2 (fr) 2002-01-24

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