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AU2001268040A1 - Methods and compounds for inhibiting mrp1 - Google Patents

Methods and compounds for inhibiting mrp1

Info

Publication number
AU2001268040A1
AU2001268040A1 AU2001268040A AU6804001A AU2001268040A1 AU 2001268040 A1 AU2001268040 A1 AU 2001268040A1 AU 2001268040 A AU2001268040 A AU 2001268040A AU 6804001 A AU6804001 A AU 6804001A AU 2001268040 A1 AU2001268040 A1 AU 2001268040A1
Authority
AU
Australia
Prior art keywords
compounds
methods
inhibiting mrp1
mrp1
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001268040A
Other languages
English (en)
Inventor
Rosanne Bonjouklian
Jeremy Schulenburg York
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU2001268040A1 publication Critical patent/AU2001268040A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2001268040A 2000-06-23 2001-06-12 Methods and compounds for inhibiting mrp1 Abandoned AU2001268040A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21338000P 2000-06-23 2000-06-23
US60213380 2000-06-23
PCT/US2001/010849 WO2002000624A2 (fr) 2000-06-23 2001-06-12 Procedes et composes d'inhibition du mrp1

Publications (1)

Publication Number Publication Date
AU2001268040A1 true AU2001268040A1 (en) 2002-01-08

Family

ID=22794896

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001268040A Abandoned AU2001268040A1 (en) 2000-06-23 2001-06-12 Methods and compounds for inhibiting mrp1

Country Status (5)

Country Link
US (1) US6686376B2 (fr)
EP (1) EP1296953A2 (fr)
AU (1) AU2001268040A1 (fr)
CA (1) CA2413579A1 (fr)
WO (1) WO2002000624A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1281210C (zh) * 2003-11-29 2006-10-25 胡汛 五味子乙素在制备治疗肿瘤药物中的应用
TWI287599B (en) * 2006-04-21 2007-10-01 Miz Engineering Ltd Multifunctional safety lock for computer
MA37700B1 (fr) 2012-06-26 2018-03-30 Bayer Pharma AG N-[4-(quinolin-4-yloxy)cyclohexyl(méthyl)](hétéro)arylcarboxamides utilisables en tant qu'antagonistes des récepteurs aux androgènes, leur production et leur utilisation en tant que médicaments
AR102537A1 (es) * 2014-11-05 2017-03-08 Flexus Biosciences Inc Agentes inmunomoduladores
JP2021515767A (ja) 2018-03-07 2021-06-24 バイエル・アクチエンゲゼルシヤフト Erk5阻害剤の同定及び使用
EP3972963A1 (fr) 2019-05-21 2022-03-30 Bayer Aktiengesellschaft Identification et utilisation d'inhibiteurs de kras

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417193B1 (en) * 1998-04-08 2002-07-09 Eli Lilly And Company Methods for inhibiting MRP1
CA2395513A1 (fr) * 1999-12-22 2001-06-28 Rosanne Bonjouklian Methodes et composes destines a inhiber mrp1

Also Published As

Publication number Publication date
WO2002000624A2 (fr) 2002-01-03
EP1296953A2 (fr) 2003-04-02
CA2413579A1 (fr) 2002-01-03
US6686376B2 (en) 2004-02-03
US20030232854A1 (en) 2003-12-18
WO2002000624A3 (fr) 2002-04-18

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