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ATE483017T1 - Transgenese in säugetieren durch intracytoplasmatische injektion von spermien - Google Patents

Transgenese in säugetieren durch intracytoplasmatische injektion von spermien

Info

Publication number
ATE483017T1
ATE483017T1 AT99941019T AT99941019T ATE483017T1 AT E483017 T1 ATE483017 T1 AT E483017T1 AT 99941019 T AT99941019 T AT 99941019T AT 99941019 T AT99941019 T AT 99941019T AT E483017 T1 ATE483017 T1 AT E483017T1
Authority
AT
Austria
Prior art keywords
sperm
coinjection
transgene
intracytoplasmatic
transgenesis
Prior art date
Application number
AT99941019T
Other languages
English (en)
Inventor
Ryuzo Yanagimachi
Original Assignee
Univ Hawaii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Hawaii filed Critical Univ Hawaii
Application granted granted Critical
Publication of ATE483017T1 publication Critical patent/ATE483017T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/60—New or modified breeds of invertebrates
    • A01K67/61—Genetically modified invertebrates, e.g. transgenic or polyploid
    • A01K67/63—Genetically modified worms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/60—New or modified breeds of invertebrates
    • A01K67/61—Genetically modified invertebrates, e.g. transgenic or polyploid
    • A01K67/65—Genetically modified arthropods
    • A01K67/67—Genetically modified crustaceans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99941019T 1998-08-11 1999-08-10 Transgenese in säugetieren durch intracytoplasmatische injektion von spermien ATE483017T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9607898P 1998-08-11 1998-08-11
US13397099P 1999-05-13 1999-05-13
PCT/US1999/018118 WO2000009674A1 (en) 1998-08-11 1999-08-10 Mammalian transgenesis by intracytoplasmic sperm injection

Publications (1)

Publication Number Publication Date
ATE483017T1 true ATE483017T1 (de) 2010-10-15

Family

ID=26791039

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99941019T ATE483017T1 (de) 1998-08-11 1999-08-10 Transgenese in säugetieren durch intracytoplasmatische injektion von spermien

Country Status (16)

Country Link
US (1) US6376743B1 (de)
EP (1) EP1105469B1 (de)
JP (1) JP3830760B2 (de)
CN (1) CN1334870A (de)
AT (1) ATE483017T1 (de)
AU (1) AU772190B2 (de)
BR (1) BR9913643A (de)
CA (1) CA2340199A1 (de)
DE (1) DE69942804D1 (de)
DK (1) DK1105469T3 (de)
HK (1) HK1044174A1 (de)
IL (1) IL141309A0 (de)
MX (1) MXPA01001389A (de)
NZ (1) NZ509634A (de)
RU (1) RU2267270C2 (de)
WO (1) WO2000009674A1 (de)

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US20030079240A1 (en) * 1997-12-18 2003-04-24 Newman Stuart A. Chimeric embryos and animals containing human cells
US7241617B2 (en) * 1998-07-03 2007-07-10 Dnavec Research, Inc. Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci
US20040088748A1 (en) * 1999-05-13 2004-05-06 Perry Anthony C.F. Method of performing transgenesis
WO2001043540A2 (en) * 1999-12-17 2001-06-21 Oregon Health And Science University Methods for producing transgenic animals
US7094601B2 (en) * 2000-05-16 2006-08-22 The General Hospital Corporation Microinjection of cryoprotectants for preservation of cells
US20020045156A1 (en) * 2000-05-16 2002-04-18 Mehmet Toner Microinjection of cryoprotectants for preservation of cells
US7049480B1 (en) 2000-09-01 2006-05-23 Avigenics, Inc. Methods of enucleating an avian oocyte or zygote using two-photon laser scanning microscopy
US20040040051A1 (en) * 2001-01-19 2004-02-26 Whitehead Institute For Biomedical Research Generation of non-human mammals by nuclear cloning
US20020116732A1 (en) * 2001-02-13 2002-08-22 Leandro Christmann Microinjection assembly and methods for microinjecting and reimplanting avian eggs
US20080124787A1 (en) * 2001-02-13 2008-05-29 Avigenics, Inc. Microinjection devices and methods of use
US7339090B2 (en) 2001-02-13 2008-03-04 Avigenics, Inc. Microinjection devices and methods of use
US7550650B2 (en) 2001-09-18 2009-06-23 Synageva Biopharma Corp. Production of a transgenic avian by cytoplasmic injection
EP1438401B1 (de) 2001-09-18 2011-06-15 Synageva BioPharma Corp. Produktion eines transgenen vogels mittels cytoplasmainjektion
US20040210955A1 (en) * 2001-10-26 2004-10-21 Hidenori Akutsu Preparation of spermatozoa for ICSI-mediated transgenesis and methods of using the same
US20040006157A1 (en) * 2002-04-26 2004-01-08 Gloster Daniel F. Ultra violet curable 100 percent solids inks
US20040172667A1 (en) * 2002-06-26 2004-09-02 Cooper Richard K. Administration of transposon-based vectors to reproductive organs
US7527966B2 (en) * 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
US20040235011A1 (en) * 2002-06-26 2004-11-25 Cooper Richard K. Production of multimeric proteins
WO2005062881A2 (en) * 2003-12-24 2005-07-14 Transgenrx, Inc. Gene therapy using transposon-based vectors
WO2005092924A2 (en) 2004-02-24 2005-10-06 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Rab9a, rab11a, and modulators thereof related to infectious disease
ES2245591B1 (es) 2004-04-06 2007-04-01 Consejo Sup. Investigaciones Cientificas Nuevo procedimiento para generar animales transgenicos no humanos, y los animales transgenicos asi obtenidos.
US20060294606A1 (en) * 2004-05-18 2006-12-28 Istefo Moisyadi Tn5 transposase-mediated transgenesis
US20060130157A1 (en) 2004-10-22 2006-06-15 Kevin Wells Ungulates with genetically modified immune systems
CN101115846A (zh) 2004-10-27 2008-01-30 范德比尔特大学 与感染相关的哺乳动物基因
CA2617930A1 (en) 2005-08-09 2007-03-29 Revivicor, Inc. Transgenic ungulates expressing ctla4-ig and uses thereof
WO2009001224A2 (en) 2007-06-22 2008-12-31 Eth Zurich Antivirals
WO2010036979A2 (en) * 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of interferon
WO2010036976A2 (en) * 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of antibodies
US9157097B2 (en) * 2008-09-25 2015-10-13 Proteovec Holding, L.L.C. Vectors for production of growth hormone
DK2348827T3 (en) 2008-10-27 2015-07-20 Revivicor Inc IMMUNICIPLY COMPROMATED PETS
EP2417263B1 (de) * 2009-04-09 2015-09-23 ProteoVec Holding L.L.C. Herstellung von proteinen unter verwendung von vektoren auf transposonbasis
US20110038852A1 (en) * 2009-06-10 2011-02-17 3-V Biosciences, Inc. Antivirals that target transporters, carriers, and ion channels
WO2012102793A2 (en) 2010-12-10 2012-08-02 Zirus, Inc. Mammalian genes involved in toxicity and infection
NZ759163A (en) 2011-02-14 2023-03-31 Revivicor Inc Genetically modified pigs for xenotransplantation of vascularized xenografts and derivatives thereof
US20150024497A1 (en) * 2013-07-19 2015-01-22 Elwha Llc Methods and Systems for Utilizing Sperm for Molecular Delivery
US20150025306A1 (en) * 2013-07-19 2015-01-22 Elwha Llc Methods and Systems for Utilizing Sperm for Molecular Delivery
RU2613788C1 (ru) * 2015-12-15 2017-03-21 Федеральное государственное бюджетное учреждение "Научный центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации Метод биопсии клеток трофобласта при множественных клетках, не участвующих в компактизации на стадии бластоцисты в программах преимплантационного генетического скрининга эмбрионов человека
BR112019001047A2 (pt) 2016-07-21 2019-04-30 ObsEva S.A. método para tratar um indivíduo submetido à terapia de transferência de embriões e kit
WO2019113743A1 (zh) * 2017-12-11 2019-06-20 清华大学 基因改造方法
KR102036723B1 (ko) 2018-02-09 2019-11-26 재단법인 대구경북과학기술원 세포질내 정자 주입 시스템 및 이를 이용한 정자 주입 방법
EP4025207A1 (de) 2019-09-03 2022-07-13 ObsEva S.A. Oxytocinantagonistdosierungsschemen zur förderung der embryoimplantation und zur vorbeugung von fehlgeburt
EP4103750A1 (de) 2020-02-10 2022-12-21 ObsEva S.A. Biomarker für eine oxytocin-rezeptor-antagonistentherapie
CN119768505A (zh) 2022-06-22 2025-04-04 加米托公司 诱导卵母细胞成熟的组合物和方法
US11744920B1 (en) 2022-08-12 2023-09-05 Gameto, Inc Implant for ovarian decline and methods of manufacturing an implant for ovarian decline
WO2024054644A2 (en) 2022-09-09 2024-03-14 Gameto, Inc. Production and applications of ovarian and uterine organoids
WO2024206245A1 (en) 2023-03-24 2024-10-03 Gameto, Inc. Methods and compositions for producing ovarian support cell co-culture
WO2025226899A1 (en) 2024-04-24 2025-10-30 Gameto, Inc Methods and compositions for producing ovarian support cell co-culture

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6641526B1 (en) * 1998-03-20 2003-11-04 University Of Hawaii Development of normal offspring from oocytes injected with freeze-dried spermatozoa
JP2002524054A (ja) 1998-08-11 2002-08-06 アンソニー・シー・エフ・ペリー 遺伝子転移を行う方法

Also Published As

Publication number Publication date
EP1105469A1 (de) 2001-06-13
HK1044174A1 (zh) 2002-10-11
CA2340199A1 (en) 2000-02-24
WO2000009674A1 (en) 2000-02-24
EP1105469A4 (de) 2004-03-10
IL141309A0 (en) 2002-03-10
EP1105469B1 (de) 2010-09-29
DK1105469T3 (da) 2010-12-20
CN1334870A (zh) 2002-02-06
NZ509634A (en) 2003-10-31
BR9913643A (pt) 2001-09-25
AU5475299A (en) 2000-03-06
JP2003521868A (ja) 2003-07-22
US6376743B1 (en) 2002-04-23
MXPA01001389A (es) 2004-01-29
RU2267270C2 (ru) 2006-01-10
AU772190B2 (en) 2004-04-08
DE69942804D1 (de) 2010-11-11
JP3830760B2 (ja) 2006-10-11

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