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ATE364840T1 - Analyse pharmazeutischer löslichkeit und stabilität - Google Patents

Analyse pharmazeutischer löslichkeit und stabilität

Info

Publication number
ATE364840T1
ATE364840T1 AT03779464T AT03779464T ATE364840T1 AT E364840 T1 ATE364840 T1 AT E364840T1 AT 03779464 T AT03779464 T AT 03779464T AT 03779464 T AT03779464 T AT 03779464T AT E364840 T1 ATE364840 T1 AT E364840T1
Authority
AT
Austria
Prior art keywords
analysis
interest
mixtures
stability
preparation
Prior art date
Application number
AT03779464T
Other languages
English (en)
Inventor
Hong Ming Chen
Hector Guzman
Colin Gardner
Original Assignee
Transform Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transform Pharmaceuticals Inc filed Critical Transform Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE364840T1 publication Critical patent/ATE364840T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00281Individual reactor vessels
    • B01J2219/00283Reactor vessels with top opening
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00308Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • B01J2219/00317Microwell devices, i.e. having large numbers of wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • B01J2219/00353Pumps
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • B01J2219/00364Pipettes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00495Means for heating or cooling the reaction vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00599Solution-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/00756Compositions, e.g. coatings, crystals, formulations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
AT03779464T 2002-11-04 2003-11-04 Analyse pharmazeutischer löslichkeit und stabilität ATE364840T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42336602P 2002-11-04 2002-11-04
US42336502P 2002-11-04 2002-11-04

Publications (1)

Publication Number Publication Date
ATE364840T1 true ATE364840T1 (de) 2007-07-15

Family

ID=32314483

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03779464T ATE364840T1 (de) 2002-11-04 2003-11-04 Analyse pharmazeutischer löslichkeit und stabilität

Country Status (9)

Country Link
US (1) US20040106098A1 (de)
EP (1) EP1558931B1 (de)
JP (1) JP2006513404A (de)
AT (1) ATE364840T1 (de)
AU (2) AU2003285143A1 (de)
DE (1) DE60314441T2 (de)
DK (1) DK1558931T3 (de)
ES (1) ES2287544T3 (de)
WO (2) WO2004042359A2 (de)

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* Cited by examiner, † Cited by third party
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JP2007523321A (ja) * 2003-12-31 2007-08-16 ユニヴァーシティー オブ サウスカロライナ 気体及び他の流体のための薄層多孔光センサ
AU2005265270B2 (en) * 2004-06-22 2011-09-22 Vertex Pharmaceuticals Incorporated Heterocyclic derivatives for modulation of calcium channels
US20070201136A1 (en) * 2004-09-13 2007-08-30 University Of South Carolina Thin Film Interference Filter and Bootstrap Method for Interference Filter Thin Film Deposition Process Control
WO2006112541A1 (ja) * 2005-04-20 2006-10-26 Chugai Seiyaku Kabushiki Kaisya 自己乳化型製剤処方の設計方法
WO2007064575A1 (en) 2005-11-28 2007-06-07 Ometric Corporation Optical analysis system and method for real time multivariate optical computing
US8345234B2 (en) * 2005-11-28 2013-01-01 Halliburton Energy Services, Inc. Self calibration methods for optical analysis system
US8358418B2 (en) * 2005-11-28 2013-01-22 Halliburton Energy Services, Inc. Optical analysis system for dynamic real-time detection and measurement
US20070166245A1 (en) 2005-11-28 2007-07-19 Leonard Mackles Propellant free foamable toothpaste composition
WO2008002903A2 (en) 2006-06-26 2008-01-03 University Of South Carolina Data validation and classification in optical analysis systems
GB0618514D0 (en) * 2006-09-20 2006-11-01 Univ Nottingham Trent Method of detecting interactions on a microarray using nuclear magnetic resonance
EP2078187A2 (de) * 2006-11-02 2009-07-15 University of South Carolina Optisches multianalyt-datenverarbeitungssystem
US8212216B2 (en) * 2007-03-30 2012-07-03 Halliburton Energy Services, Inc. In-line process measurement systems and methods
WO2008121684A1 (en) * 2007-03-30 2008-10-09 University Of South Carolina Novel multi-analyte optical computing system
US8184295B2 (en) * 2007-03-30 2012-05-22 Halliburton Energy Services, Inc. Tablet analysis and measurement system
US8283633B2 (en) * 2007-11-30 2012-10-09 Halliburton Energy Services, Inc. Tuning D* with modified thermal detectors
US8212213B2 (en) * 2008-04-07 2012-07-03 Halliburton Energy Services, Inc. Chemically-selective detector and methods relating thereto
WO2012128603A1 (fr) 2011-03-22 2012-09-27 Aouad Salah Mohammed Dispositif automatique et procede de preparation de solutions
US20140045724A1 (en) * 2012-08-10 2014-02-13 Jon Selbo Formulation screening methods, apparatuses for performing such methods and formulations formed by such methods
MA41872B1 (fr) * 2015-08-03 2020-10-28 Mohammed Salah Aouad Dispositif et procede pour le developement de formulations
JP7012731B2 (ja) * 2016-10-25 2022-02-14 アボット・ラボラトリーズ 自動スライド作製における試薬の評価及び制御
CN120084774B (zh) * 2025-05-06 2025-09-12 中国科学院地质与地球物理研究所 原位测定dac中矿物体积和溶解度的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9424125D0 (en) * 1994-11-23 1995-01-18 Univ Cranfield Electrochemical sensor and novel media for bioelectrochemical reactions
US5616621A (en) * 1995-01-30 1997-04-01 American Home Products Corporation Taste masking liquids
US5699934A (en) * 1996-01-29 1997-12-23 Universal Instruments Corporation Dispenser and method for dispensing viscous fluids
CA2258489C (en) * 1996-06-28 2004-01-27 Caliper Technologies Corporation High-throughput screening assay systems in microscale fluidic devices
US6544193B2 (en) * 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US6004967A (en) * 1996-09-13 1999-12-21 Sugen, Inc. Psoriasis treatment with quinazoline compounds
US6109717A (en) * 1997-05-13 2000-08-29 Sarnoff Corporation Multi-element fluid delivery apparatus and methods
DE69820877T2 (de) * 1997-08-15 2005-03-03 Bioprocessors Corp., Woburn Vorrichtung zur durchführung von nachweisen an reaktionsstellen
US6485703B1 (en) * 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
WO2000033818A1 (en) * 1998-12-11 2000-06-15 Nostrum Pharmaceuticals, Inc. Sustained release tablet containing hydrocolloid and cellulose ether
AU2930501A (en) * 2000-01-07 2001-07-24 Transform Pharmaceuticals, Inc. High-throughput formation, identification, and analysis of diverse solid-forms
US20010044112A1 (en) * 2000-03-24 2001-11-22 Lyles Mark B. High throughput screening array containing porous material
EP1417626A2 (de) * 2001-07-13 2004-05-12 Pharmacopeia, Inc. System und verfahren zur vorhersage der wasserlöslichkeit
US20030119060A1 (en) * 2001-08-10 2003-06-26 Desrosiers Peter J. Apparatuses and methods for creating and testing pre-formulations and systems for same
WO2003023394A2 (en) * 2001-09-12 2003-03-20 Phares Pharmaceutical Research N.V. Kit for screening compounds with low water solubility
US20030230488A1 (en) * 2002-06-13 2003-12-18 Lawrence Lee Microfluidic device preparation system
AU2003264805A1 (en) * 2002-10-18 2004-05-04 Brian David Bissett Automated kinetci solubility assay apparatus and method

Also Published As

Publication number Publication date
ES2287544T3 (es) 2007-12-16
EP1558931B1 (de) 2007-06-13
WO2004042359A2 (en) 2004-05-21
EP1558931A2 (de) 2005-08-03
WO2004041202A2 (en) 2004-05-21
JP2006513404A (ja) 2006-04-20
EP1558931A4 (de) 2006-08-30
AU2003287491A1 (en) 2004-06-07
WO2004042359A3 (en) 2004-08-05
DE60314441T2 (de) 2008-02-21
AU2003287491A8 (en) 2004-06-07
DE60314441D1 (de) 2007-07-26
WO2004041202A3 (en) 2004-07-22
AU2003285143A8 (en) 2004-06-07
DK1558931T3 (da) 2007-10-15
US20040106098A1 (en) 2004-06-03
AU2003285143A1 (en) 2004-06-07

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