[go: up one dir, main page]

ATE293453T1 - Verbindungen zur behandlung von sexuellen funktionsstörungen - Google Patents

Verbindungen zur behandlung von sexuellen funktionsstörungen

Info

Publication number
ATE293453T1
ATE293453T1 AT00950283T AT00950283T ATE293453T1 AT E293453 T1 ATE293453 T1 AT E293453T1 AT 00950283 T AT00950283 T AT 00950283T AT 00950283 T AT00950283 T AT 00950283T AT E293453 T1 ATE293453 T1 AT E293453T1
Authority
AT
Austria
Prior art keywords
treatment
sexual dysfunction
compounds
phe
arg
Prior art date
Application number
AT00950283T
Other languages
English (en)
Inventor
Christine H Blood
Annette M Shadiack
Joanna K Bernstein
Guy W Herbert
Original Assignee
Palatin Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palatin Technologies Inc filed Critical Palatin Technologies Inc
Application granted granted Critical
Publication of ATE293453T1 publication Critical patent/ATE293453T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68Melanocyte-stimulating hormone [MSH]
    • C07K14/685Alpha-melanotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
AT00950283T 1999-06-29 2000-06-29 Verbindungen zur behandlung von sexuellen funktionsstörungen ATE293453T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14234699P 1999-06-29 1999-06-29
US19498700P 2000-04-05 2000-04-05
US09/606,501 US6579968B1 (en) 1999-06-29 2000-06-28 Compositions and methods for treatment of sexual dysfunction
PCT/US2000/018217 WO2001000224A1 (en) 1999-06-29 2000-06-29 Compositions and methods for treatment of sexual dysfunction

Publications (1)

Publication Number Publication Date
ATE293453T1 true ATE293453T1 (de) 2005-05-15

Family

ID=27385799

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00950283T ATE293453T1 (de) 1999-06-29 2000-06-29 Verbindungen zur behandlung von sexuellen funktionsstörungen

Country Status (15)

Country Link
US (3) US6579968B1 (de)
EP (1) EP1196184B8 (de)
JP (1) JP4576493B2 (de)
KR (1) KR101021632B1 (de)
AT (1) ATE293453T1 (de)
AU (1) AU783718B2 (de)
BR (1) BR0012200B1 (de)
CA (1) CA2376978C (de)
DE (1) DE60019598T2 (de)
ES (1) ES2235921T3 (de)
HK (1) HK1047881B (de)
MX (1) MXPA02000111A (de)
NZ (1) NZ516030A (de)
PT (1) PT1196184E (de)
WO (1) WO2001000224A1 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064091A2 (en) 2001-02-13 2002-08-22 Palatin Technologies, Inc. Melanocortin metallopeptides for treatment of sexual dysfunction
US7258850B2 (en) * 1999-05-04 2007-08-21 Aradigm Corporation Methods and compositions for treating erectile dysfunction
CA2377369A1 (en) 1999-06-04 2000-12-14 Merck & Co., Inc. Substituted piperidines as melanocortin-4 receptor agonists
US7235625B2 (en) * 1999-06-29 2007-06-26 Palatin Technologies, Inc. Multiple agent therapy for sexual dysfunction
US7176279B2 (en) * 2000-06-28 2007-02-13 Palatin Technologies, Inc. Cyclic peptide compositions and methods for treatment of sexual dysfunction
US6579968B1 (en) * 1999-06-29 2003-06-17 Palatin Technologies, Inc. Compositions and methods for treatment of sexual dysfunction
CN1571796A (zh) * 2000-09-27 2005-01-26 宝洁公司 黑皮素受体配体
US7342089B2 (en) * 2001-07-11 2008-03-11 Palatin Technologies, Inc. Cyclic peptides for treatment for cachexia
US7354923B2 (en) * 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
JP2005504043A (ja) * 2001-08-10 2005-02-10 パラチン テクノロジーズ インク. 生物学的に活性な金属ペプチド類のペプチド模倣体類
US7655658B2 (en) * 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7456184B2 (en) * 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
US7732451B2 (en) * 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
US6873883B2 (en) * 2001-12-26 2005-03-29 Hewlett-Packard Development Company, L.P. Adaptive fan controller for a computer system
US20030229025A1 (en) * 2002-02-25 2003-12-11 Chiron Corporation Intranasal administration of MC4-R agonists
US8043287B2 (en) * 2002-03-05 2011-10-25 Kimberly-Clark Inc. Method of treating biological tissue
DE10228837B4 (de) * 2002-06-27 2016-01-07 Elfriede Rauch Hautkosmetische Zusammensetzung und Verwendung der Zusammensetzung als Hautbräunungsmittel
AU2003248888A1 (en) * 2002-07-09 2004-01-23 Palatin Technologies, Inc. Peptide composition for treatment of sexual dysfunction
JPWO2004075920A1 (ja) * 2003-02-26 2006-06-01 大塚製薬株式会社 経肺投与用徐放性製剤学的組成物
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
US7968548B2 (en) 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US20050101535A1 (en) * 2003-05-06 2005-05-12 Rosenstein David H. Use of a synthetic alpha-melanocyte stimulating hormone agonist to decrease steroid induced weight gain
US20060293223A1 (en) * 2003-06-19 2006-12-28 Eli Lilly And Company Patent Division Uses of melanocortin-3 receptor (mc3r) agonist peptides
JP2006527773A (ja) * 2003-06-19 2006-12-07 イーライ リリー アンド カンパニー メラノコルチン受容体4(mc4)作用薬とその用途
WO2005030797A2 (en) 2003-09-30 2005-04-07 Novo Nordisk A/S Melanocortin receptor agonists
US7550602B1 (en) 2004-01-14 2009-06-23 Palatin Technologies, Inc. Small molecule compositions for sexual dysfunction
US7649002B2 (en) 2004-02-04 2010-01-19 Pfizer Inc (3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists
US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
BRPI0510074A (pt) * 2004-04-22 2007-10-16 Boehringer Ingelheim Int composições farmacêuticas para o tratamento de distúrbios sexuais ii
TW200626611A (en) * 2004-09-20 2006-08-01 Lonza Ag Peptide cyclisation
WO2006060873A1 (en) * 2004-12-09 2006-06-15 Prince Henry's Institute Of Medical Research Method for restoring reproductive function
EP2548568B1 (de) * 2005-07-08 2018-01-10 Ipsen Pharma Melanocortinrezeptorliganden
PL1912650T3 (pl) 2005-08-03 2018-01-31 Sprout Pharmaceuticals Inc Zastosowanie flibanseryny w leczeniu otyłości
JP2009503050A (ja) * 2005-08-04 2009-01-29 ファイザー・リミテッド ピペリジノイル−ピロリジンおよびピペリジノイル−ピペリジン化合物
EP1957096A4 (de) * 2005-08-29 2012-03-21 Palatin Technologies Inc Zyklische peptid-isolierung durch sprühtrocknung
CA2626134C (en) 2005-10-29 2013-12-24 Boehringer Ingelheim International Gmbh Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders
US8247530B2 (en) * 2005-11-08 2012-08-21 Palatin Technologies, Inc. N-alkylated cyclic peptide melanocortin agonists
CN101092451B (zh) * 2006-06-20 2011-02-09 中国人民解放军军事医学科学院毒物药物研究所 Pt-141和mt-ⅱ的固相合成方法
EP2037927B1 (de) 2006-06-30 2010-01-27 Boehringer Ingelheim International GmbH Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen
US7834017B2 (en) 2006-08-11 2010-11-16 Palatin Technologies, Inc. Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
AR062320A1 (es) 2006-08-14 2008-10-29 Boehringer Ingelheim Int Formulaciones de flibanserina y metodo para fabricarlas
WO2008022932A2 (en) 2006-08-25 2008-02-28 Boehringer Ingelheim International Gmbh Controlled release system and method for manufacturing the same
CN101195654B (zh) * 2006-12-08 2011-06-15 上海吉尔多肽有限公司 一种美拉诺坦-ⅱ的固相合成方法
US8722682B2 (en) 2006-12-20 2014-05-13 Sprout Pharmaceuticals, Inc. Sulfated benzimidazolone derivatives having mixed serotonin receptor affinity
WO2008091355A2 (en) * 2007-01-24 2008-07-31 Breathe Pharmaceuticals, Inc. Drug transfer device
CN101280005B (zh) * 2007-04-06 2013-03-13 扬子江药业集团四川海蓉药业有限公司 普美拉肽的制备方法
CL2008002693A1 (es) 2007-09-12 2009-10-16 Boehringer Ingelheim Int Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad
WO2009120656A1 (en) * 2008-03-24 2009-10-01 Palatin Technologies, Inc. Pharmaceutical for ocular indications
WO2009144433A1 (en) * 2008-05-30 2009-12-03 Palatin Technologies, Inc. Methods for selection of melanocortin 4 receptor-specific agents for treatment of obesity
EP2300036B1 (de) 2008-06-09 2017-04-05 Palatin Technologies, Inc. Melanocortin-rezeptor-spezifische peptide zur behandlung von sexueller dysfunktion
US20090305960A1 (en) * 2008-06-09 2009-12-10 Palatin Technologies, Inc Melanocortin Receptor-Specific Peptides for Treatment of Obesity / 669
EP2898900B1 (de) 2008-09-19 2017-11-15 Nektar Therapeutics Polymerkonjugate von Ziconotid
EP2440572B1 (de) 2009-06-08 2017-04-05 Palatin Technologies, Inc. Lactam-gebrückte melanocortinrezeptorspezifische peptide
NZ596617A (en) * 2009-06-08 2014-04-30 Palatin Technologies Inc Melanocortin receptor-specific peptides
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
NZ599774A (en) 2009-11-23 2014-11-28 Palatin Technologies Inc Melanocortin-1 receptor-specific cyclic peptides
CA2781405A1 (en) 2009-11-23 2011-05-26 Palatin Technologies, Inc. Melanocortin-1 receptor-specific linear peptides
US9782454B2 (en) 2010-04-22 2017-10-10 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
KR102038677B1 (ko) 2011-06-14 2019-10-30 입센 파마 에스.에이.에스 활성 성분으로 멜라노코르틴 수용체 리간드를 함유하는 지속-방출형 조성물
US9402877B2 (en) 2011-11-04 2016-08-02 Xion Pharmaceuticals Corporation Methods and compositions for oral administration of melanocortin receptor agonist compounds
FI2916856T4 (fi) 2012-11-05 2024-01-15 Palatin Technologies Inc Bremelanotidin käyttöjä naisen seksuaalisen toimintahäiriön hoidossa
US9834580B2 (en) 2012-11-21 2017-12-05 University Of Cincinnati Pharmaceutical compositions comprising selective peptide-based agonists of melanocortin 1 receptor
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
US9814755B2 (en) 2014-06-10 2017-11-14 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for the treatment of depression and anxiety
US20170022252A1 (en) 2014-06-10 2017-01-26 The Arizona Board Of Regents On Behalf Of The University Of Arizona Novel modulators of melanocortin receptors
US9821023B2 (en) 2014-06-10 2017-11-21 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for the treatment of central nervous system (CNS) disorders and mood disorders
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
US10550157B2 (en) 2015-10-16 2020-02-04 Arizona Board Of Regent On Behalf Of The University Of Arizona Compositions and methods for treating central nervous system (CNS) disorders and mood disorders
WO2017066769A1 (en) * 2015-10-16 2017-04-20 The Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating central nervous system (cns) disorders and mood disorders
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
CN106243214B (zh) * 2016-08-29 2019-12-10 济南康和医药科技有限公司 一种美拉诺坦ⅰ的制备方法
RU2655763C2 (ru) * 2016-10-24 2018-05-29 Общество С Ограниченной Ответственностью "Айвикс" Фармацевтическая композиция и способ лечения женских сексуальных дисфункций
US11590209B2 (en) 2020-01-21 2023-02-28 Palatin Technologies, Inc. Use of bremelanotide in patients with controlled hypertension
CN115279390A (zh) * 2020-02-03 2022-11-01 帕拉丁科技公司 反向酰胺连接的促黑素受体特异性环状肽
EP4100040A4 (de) * 2020-02-03 2024-06-05 Palatin Technologies, Inc. Diaminverknüpfte rezeptorspezifische zyklische peptide

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862928A (en) * 1969-07-09 1975-01-28 Akzona Inc Psychopharmacological hexa-peptides containing a d-phenylalanyl residue
BE795788A (nl) * 1972-02-22 1973-08-22 Akzo Nv Werkwijze ter bereiding van peptiden en peptide-derivaten en de toepassing hiervan
US4649191A (en) * 1984-05-10 1987-03-10 Gibson-Stephens Neuropharmaceuticals, Inc. Conformationally constrained alpha-melanotropin analogs with specific central nervous system activity
US4623715A (en) * 1984-10-22 1986-11-18 Hoechst Aktiengeselleschaft Novel peptides which are active on the central nervous system and have an action on the cholinergic system
US5674839A (en) 1987-05-22 1997-10-07 Competitive Technologies, Inc. Cyclic analogs of alpha-MSH fragments
JP3219096B2 (ja) 1990-05-10 2001-10-15 ニコメド ファーマ エイエス n―グリコフロール類及びn―エチレングリコール類を含有する医薬製剤
FR2691465B1 (fr) * 1992-05-25 1995-08-11 Pf Medicament Complexes comprenant au moins un peptide derive de l'alpha msh, peptide, microsphere, medicament et composition galenique les comprenant.
US5977070A (en) 1992-07-14 1999-11-02 Piazza; Christin Teresa Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
EP0696919B1 (de) 1993-04-05 2002-01-30 Competitive Technologies, Inc. Diagnose und behandlung von erektilen funktionsstörungen
US5420109A (en) * 1993-11-12 1995-05-30 Houghten Pharmaceuticals, Inc. Cytokine restraining agents
US6054556A (en) 1995-04-10 2000-04-25 The Arizona Board Of Regents On Behalf Of The University Of Arizona Melanocortin receptor antagonists and agonists
FR2735131B1 (fr) * 1995-06-12 1997-08-22 Rech De Pathologie Appliquee S Conjugues d'msh avec un acide gras, leur procede de preparation et leur utilisation a titre de medicament
US5908825A (en) 1997-01-09 1999-06-01 University Of Maryland At Baltimore Dosage composition for nasal delivery and method of use of the same
WO1999021571A1 (en) 1997-10-27 1999-05-06 Trega Biosciences, Inc. Melanocortin receptor ligands and methods of using same
US6228840B1 (en) 1998-02-27 2001-05-08 Edward T. Wei Melanocortin receptor antagonists and modulations of melanocortin receptor activity
US6127381A (en) 1998-04-28 2000-10-03 Basu; Amaresh Isoquinoline compound melanocortin receptor ligands and methods of using same
AU742425B2 (en) 1998-06-11 2002-01-03 Merck & Co., Inc. Spiropiperidine derivatives as melanocortin receptor agonists
US6579968B1 (en) * 1999-06-29 2003-06-17 Palatin Technologies, Inc. Compositions and methods for treatment of sexual dysfunction

Also Published As

Publication number Publication date
EP1196184A4 (de) 2003-05-28
US6579968B1 (en) 2003-06-17
US6794489B2 (en) 2004-09-21
BR0012200A (pt) 2002-03-26
US20020107182A1 (en) 2002-08-08
ES2235921T3 (es) 2005-07-16
WO2001000224A1 (en) 2001-01-04
JP2003503357A (ja) 2003-01-28
DE60019598D1 (de) 2005-05-25
DE60019598T2 (de) 2005-09-29
EP1196184A1 (de) 2002-04-17
HK1047881B (en) 2005-10-14
CA2376978A1 (en) 2001-01-04
AU6340700A (en) 2001-01-31
EP1196184B1 (de) 2005-04-20
CA2376978C (en) 2012-11-20
PT1196184E (pt) 2005-08-31
KR101021632B1 (ko) 2011-03-17
KR20020016876A (ko) 2002-03-06
MXPA02000111A (es) 2003-07-21
HK1047881A1 (en) 2003-03-14
EP1196184B8 (de) 2005-06-15
NZ516030A (en) 2004-10-29
JP4576493B2 (ja) 2010-11-10
AU783718B2 (en) 2005-12-01
BR0012200B1 (pt) 2013-08-06
US20050037951A1 (en) 2005-02-17

Similar Documents

Publication Publication Date Title
ATE293453T1 (de) Verbindungen zur behandlung von sexuellen funktionsstörungen
WO2005014617A3 (en) Cyclic peptide compositions and methods for treatment of sexual dysfunction
CY1107051T1 (el) Αντι-διηθητικα και αντι-αγγειογενετικα θραυσματα ουροκινασης και η χρηση τους
CA2338005A1 (en) Peptide antagonists of zonulin and methods for use of the same
EP1159964A3 (de) Zusammenstellungen und Methoden zur Förderung der Beweglichkeit des Verdauungstrakts
NZ516477A (en) Therapeutic methods and compositions for the treatment of impaired interpersonal and behavioral disorders
BG106008A (en) Novel lhrh antagonists with improved solubility characteristics
IL136733A0 (en) Pharmaceutical composition containing sibutramine and orlistat
HUP0001431A2 (hu) Módosított tandem peptid, ezt tartalmazó immunogén gyógyászati készítmény és vakcina az LHRH hormon termelés ellen, és eljárás a sertéshús minőségének javítására
MXPA02012730A (es) Uso de acido pamoico o uno de sus derivados o uno de sus analogos para la preparacion de un medicamento para el tratamiento de enfermedades caracterizadas por depositos de agregados de amiloide.
WO2002058589A3 (en) Agents and methods for promoting bone growth
IT1244496B (it) Impiego terapeutico dei peptidi della somatostatina.
RU2003127718A (ru) Применение флумазенила в производстве лекарственного средства для лечения кокаиновой зависимости
MXPA02008870A (es) Novedosos antagonistas de lhrh, produccion de los mismos y sus uso como medicamentos.
EP1593384A3 (de) Verbindungen zur Behandlung von sexuellen Funktionsstörungen
DE69430416D1 (de) Zusammensetzungen aus Aminosäure zur Behandlung von Infektionen
MXPA01012936A (es) Composicion farmaceutica que contiene sibutramina y orlistat.
BR0015446A (pt) Peptìdios para o tratamento de disfunção erétil
BG103905A (en) New bpc peptide salts with organoprotective activity, method for their preparation and application in medicine
DE602004019141D1 (de) Isoleucyl-valyl-threonyl-asparaginyl-threonyl-threonin (ivtntt) enthaltende biologisch wirksame peptide
MY134074A (en) Pharmaceutical composition comprising gamma-butyrobetaine for treatment of impotence
JPH0372044B2 (de)
ATE280584T1 (de) Verwendung von beta interferon zur herstellung eines arzneimittels zur behandlung von ewings sarkom und eoe
UA36167A (uk) Спосіб лікування панкреатиту
MD1469G2 (ro) Metodă de tratament al şocului combustional

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1196184

Country of ref document: EP