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ATE267210T1 - Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden - Google Patents

Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden

Info

Publication number
ATE267210T1
ATE267210T1 AT99943807T AT99943807T ATE267210T1 AT E267210 T1 ATE267210 T1 AT E267210T1 AT 99943807 T AT99943807 T AT 99943807T AT 99943807 T AT99943807 T AT 99943807T AT E267210 T1 ATE267210 T1 AT E267210T1
Authority
AT
Austria
Prior art keywords
cis
diol cyclic
boronate
reversible
cyclic peptides
Prior art date
Application number
AT99943807T
Other languages
English (en)
Inventor
Brian Allen Moser
Jeffrey Clayton Baker
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE267210T1 publication Critical patent/ATE267210T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99943807T 1998-08-28 1999-08-18 Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden ATE267210T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9826798P 1998-08-28 1998-08-28
PCT/US1999/019066 WO2000012540A1 (en) 1998-08-28 1999-08-18 Reversible boronate complexes of 1,2-cis-diol cyclic-peptides

Publications (1)

Publication Number Publication Date
ATE267210T1 true ATE267210T1 (de) 2004-06-15

Family

ID=22268490

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99943807T ATE267210T1 (de) 1998-08-28 1999-08-18 Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden

Country Status (6)

Country Link
EP (1) EP1107982B1 (de)
AT (1) ATE267210T1 (de)
AU (2) AU763351B2 (de)
CA (1) CA2340647A1 (de)
DE (1) DE69917467D1 (de)
WO (1) WO2000012540A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
ATE287899T1 (de) 1998-08-20 2005-02-15 Lilly Co Eli Verfahren zur herstellung von ring-modifizierten zyklischen peptidanalogen
JP2003511345A (ja) 1998-12-09 2003-03-25 イーライ リリー アンド カンパニー Ｅｃｈｉｎｏｃａｎｄｉｎシクロペプチド化合物の精製
KR20020003864A (ko) 1999-03-03 2002-01-15 피터 지. 스트링거 에키노칸딘/탄수화물 착물
BR0008713A (pt) 1999-03-03 2001-12-26 Lilly Co Eli Processos para preparar formulações ecomposições farmacêuticas orais com ecb
IL145186A0 (en) 1999-03-03 2002-06-30 Lilly Co Eli Formation and anion-exchange of crystalline echinocandin ammonium salts
RU2250763C2 (ru) 1999-03-03 2005-04-27 Эли Лилли Энд Компани Фармацевтические препараты эхинокандина, содержащие мицелообразующие поверхностно-активные вещества
AR035808A1 (es) * 2001-04-12 2004-07-14 Merck & Co Inc Proceso de deshidratacion capaz de minimizar la epimerizacion de un grupo hidroxilo por ciertas equinocandinas
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
WO2005119255A2 (en) * 2004-05-12 2005-12-15 Applera Corporation Constrained cis-diol-borate bioconjugation system
ES2461596T3 (es) * 2009-05-07 2014-05-20 Dsm Sinochem Pharmaceuticals Netherlands B.V. Método para la preparación de ciclopéptidos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631364A (en) * 1994-03-31 1997-05-20 Axis Biochemicals Asa Labelled boronic acid derivatives
HRP970318B1 (en) * 1996-06-14 2002-06-30 Merck & Co Inc A process for preparing certain aza cyclohexapeptides

Also Published As

Publication number Publication date
AU5683499A (en) 2000-03-21
WO2000012540A1 (en) 2000-03-09
EP1107982B1 (de) 2004-05-19
EP1107982A1 (de) 2001-06-20
CA2340647A1 (en) 2000-03-09
AU2003252851A1 (en) 2003-11-06
DE69917467D1 (de) 2004-06-24
AU763351B2 (en) 2003-07-17

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties