ATE266638T1 - Verbindungen mit analgetischer wirkung - Google Patents

Verbindungen mit analgetischer wirkung

Info

Publication number: ATE266638T1
Authority: AT; Austria
Prior art keywords: compounds; analgesic action; analgesic; action
Prior art date: 1996-12-20

Application number

AT97950539T

Other languages

English (en)

Inventor

Benjamin Pelcman

Edward Roberts

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-20

Filing date

1997-12-09

Publication date

2004-05-15

1997-12-09 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE266638T1 publication Critical patent/ATE266638T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Physics & Mathematics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Optics & Photonics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrrole Compounds (AREA)

AT97950539T 1996-12-20 1997-12-09 Verbindungen mit analgetischer wirkung ATE266638T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9604786A SE9604786D0 (sv)	1996-12-20	1996-12-20	New compounds
PCT/SE1997/002051 WO1998028270A1 (en)	1996-12-20	1997-12-09	Novel compounds with analgesic effect

Publications (1)

Publication Number	Publication Date
ATE266638T1 true ATE266638T1 (de)	2004-05-15

Family

ID=20405139

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97950539T ATE266638T1 (de)	1996-12-20	1997-12-09	Verbindungen mit analgetischer wirkung

Country Status (31)

Country	Link
US (3)	US6153626A (de)
EP (2)	EP1428821A1 (de)
JP (1)	JP2001507021A (de)
KR (1)	KR20000069600A (de)
CN (2)	CN1539824A (de)
AR (1)	AR010378A1 (de)
AT (1)	ATE266638T1 (de)
AU (1)	AU738002B2 (de)
BR (1)	BR9713785A (de)
CA (1)	CA2274117A1 (de)
CZ (1)	CZ220099A3 (de)
DE (1)	DE69729115T2 (de)
DK (1)	DK0946510T3 (de)
EE (1)	EE03966B1 (de)
ES (1)	ES2219783T3 (de)
HU (1)	HUP0000613A3 (de)
ID (1)	ID21662A (de)
IL (1)	IL130536A0 (de)
IS (1)	IS5078A (de)
MY (1)	MY132705A (de)
NO (1)	NO313632B1 (de)
NZ (1)	NZ336028A (de)
PL (1)	PL188945B1 (de)
PT (1)	PT946510E (de)
RU (1)	RU2193030C2 (de)
SE (1)	SE9604786D0 (de)
SK (1)	SK283300B6 (de)
TR (1)	TR199901411T2 (de)
UA (1)	UA54481C2 (de)
WO (1)	WO1998028270A1 (de)
ZA (1)	ZA9711049B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
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SE9504661D0 (sv)	1995-12-22	1995-12-22	Astra Pharma Inc	New compounds
TW548271B (en) *	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
US6974825B1 (en)	1996-12-20	2005-12-13	Astrazeneca Canada Inc.	Compounds with analgesic effect
SE9604786D0 (sv)	1996-12-20	1996-12-20	Astra Pharma Inc	New compounds
AU2009799A (en) *	1997-12-24	1999-07-19	Ortho-Mcneil Pharmaceutical, Inc.	4-(aryl(piperidin-4-yl)) aminobenzamides which bind to the delta-opioid receptor
AU2003220725B2 (en) *	1997-12-24	2006-06-01	Ortho-Mcneil Pharmaceutical, Inc.	4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor
US6900228B1 (en)	1998-03-10	2005-05-31	Research Triangle Institute	Opiate compounds, methods of making and methods of use
AU756983B2 (en) *	1998-03-10	2003-01-30	Research Triangle Institute	Novel opiate compounds, methods of making and methods of use
US6436959B1 (en)	1998-12-23	2002-08-20	Ortho-Mcneil Pharmaceutical, Inc.	4-[aryl(piperidin-4-yl)]aminobenzamides
SE9904674D0 (sv) *	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
SE9904673D0 (sv)	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
SE9904675D0 (sv) *	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
AU2063601A (en)	1999-12-22	2001-07-03	Ortho-Mcneil Pharmaceutical, Inc.	4-(aryl(8-azabicyclo(3.2.1)octan-3-yl))aminobenzoic acid derivatives
AU3231901A (en)	2000-02-18	2001-08-27	Meiji Seika Kaisha	Phenoxyalkylamine derivatives useful as opioid delta receptor agonists
CN1426411A (zh)	2000-03-03	2003-06-25	奥索-麦克尼尔药品公司	3－(二芳基亚甲基)－8－氮杂双环[3.2.1]辛烷衍生物
US6790854B2 (en)	2000-03-24	2004-09-14	Meiji Seika Kaisha, Ltd.	Diphenylalkylamine derivatives useful as opioid receptor agonists
SE0001209D0 (sv)	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
US6887876B2 (en)	2000-12-14	2005-05-03	Ortho-Mcneil Pharmaceutical, Inc.	Benzamidine derivatives
CA2436263A1 (en) *	2000-12-15	2002-06-20	Astrazeneca Ab	New process for the preparation diaryl-4-amino-piperidinyl compounds
SE0101773D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101769D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101770D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101771D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
US7229994B2 (en)	2001-05-18	2007-06-12	Astrazeneca Ab	4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
ATE347549T1 (de)	2001-10-15	2006-12-15	Janssen Pharmaceutica Nv	Neue substituierte 4-phenyl-4-(1h-imidazo-2-yl)- piperidin-derivate und ihre anwendung als selective delta-opioid-agonisten
ES2347544T3 (es) *	2002-03-13	2010-11-02	Janssen Pharmaceutica Nv	Inhibidores de histona-desacetilasas.
EP1507756B1 (de)	2002-05-24	2015-07-22	Millennium Pharmaceuticals, Inc.	Ccr9-inhibitoren und verfahren zu deren verwendung
SE0203300D0 (sv)	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0203303D0 (sv)	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
SE0203302D0 (sv)	2002-11-07	2002-11-07	Astrazeneca Ab	Novel Compounds
US7741519B2 (en)	2007-04-23	2010-06-22	Chemocentryx, Inc.	Bis-aryl sulfonamides
US7420055B2 (en)	2002-11-18	2008-09-02	Chemocentryx, Inc.	Aryl sulfonamides
US7227035B2 (en)	2002-11-18	2007-06-05	Chemocentryx	Bis-aryl sulfonamides
EP1562940B1 (de)	2002-11-18	2007-05-30	ChemoCentryx Inc	Arylsulfonamide
ATE407117T1 (de) *	2003-01-16	2008-09-15	Acadia Pharm Inc	Selektive serotonin 2a/2c inverse rezeptoragonisten als therapeutika für neurodegenerative erkrankungen
AU2004253898A1 (en)	2003-06-27	2005-01-13	Janssen Pharmaceutica N.V.	Tricyclic delta opioid modulators
WO2005075472A1 (en)	2004-02-03	2005-08-18	Janssen Pharmaceutica, N.V.	3-(diheteroarylnethylene)-8-azabicyclo[3.2.1]octane and 3-(aryl)(heteroaryl)methylene)-8-azabicyclo[3.2.1]octane derivatives
MX2007001240A (es)	2004-08-02	2007-03-23	Astrazeneca Ab	Derivados de diarilmetil-piperazina, preparaciones y usos de las mismas.
EA200700403A1 (ru) *	2004-08-05	2007-08-31	Янссен Фармацевтика Н.В.	ТРИЦИКЛИЧЕСКИЕ δ-ОПИОИДНЫЕ МОДУЛЯТОРЫ
MX2007007627A (es) *	2004-12-22	2008-01-28	Johnson & Johnson	Moduladores delta-opioides triciclicos.
BRPI0519198A2 (pt) *	2004-12-22	2008-12-30	Janssen Pharmaceutica Nv	moduladores de delta-opiàide tricÍclicos
KR20070092293A (ko) *	2004-12-22	2007-09-12	얀센 파마슈티카 엔.브이.	트리사이클릭 δ-오피오이드 모듈레이터
US7432257B2 (en) *	2005-01-06	2008-10-07	Janssen Pharmaceutica N.V.	Piperdinyl-phenoxazine and phenothiazine derivatives as δ-opioid modulators
TWI449692B (zh)	2005-05-13	2014-08-21	Otsuka Pharma Co Ltd	吡咯烷化合物（三）
EP1896467B1 (de) *	2005-06-16	2010-12-01	Janssen Pharmaceutica NV	Tricyclische opioidmodulatoren
JP5219465B2 (ja) *	2006-11-10	2013-06-26	大塚製薬株式会社	医薬

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EG12406A (en) *	1976-08-12	1979-03-31	Janssen Pharmaceutica Nv	Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
SE441448B (sv) *	1977-05-23	1985-10-07	Pfizer	Sett att framstella hexahydro-gamma-karbolinforeningar
DE3200304A1 (de) *	1981-01-16	1982-08-26	Sandoz-Patent-GmbH, 7850 Lörrach	3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3563964D1 (en) *	1984-10-16	1988-09-01	Synthelabo	Piperidine derivatives, their preparation and their therapeutical application
KR940003491B1 (ko)	1989-08-10	1994-04-23	리히터 게데온 베기에스제티 기아르 알.티	4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
YU150489A (sh)	1989-08-10	1992-12-21	W.L. Gore & Co. Gmbh.	Uređaj za ispitivanje odevnih predmeta na nepromočivost
SE8904298D0 (sv) *	1989-12-21	1989-12-21	Astra Ab	New compounds
GB9202238D0 (en) *	1992-02-03	1992-03-18	Wellcome Found	Compounds
US5854245A (en) *	1996-06-28	1998-12-29	Merck & Co., Inc.	Fibrinogen receptor antagonists
SE9604786D0 (sv) *	1996-12-20	1996-12-20	Astra Pharma Inc	New compounds
TW548271B (en) *	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
AU2009799A (en) *	1997-12-24	1999-07-19	Ortho-Mcneil Pharmaceutical, Inc.	4-(aryl(piperidin-4-yl)) aminobenzamides which bind to the delta-opioid receptor
AU756983B2 (en)	1998-03-10	2003-01-30	Research Triangle Institute	Novel opiate compounds, methods of making and methods of use
US6436959B1 (en)	1998-12-23	2002-08-20	Ortho-Mcneil Pharmaceutical, Inc.	4-[aryl(piperidin-4-yl)]aminobenzamides

1996
- 1996-12-20 SE SE9604786A patent/SE9604786D0/xx unknown
1997
- 1997-09-12 UA UA99074131A patent/UA54481C2/uk unknown
- 1997-12-09 WO PCT/SE1997/002051 patent/WO1998028270A1/en not_active Ceased
- 1997-12-09 ES ES97950539T patent/ES2219783T3/es not_active Expired - Lifetime
- 1997-12-09 CZ CZ992200A patent/CZ220099A3/cs unknown
- 1997-12-09 US US09/029,468 patent/US6153626A/en not_active Expired - Lifetime
- 1997-12-09 ZA ZA9711049A patent/ZA9711049B/xx unknown
- 1997-12-09 BR BR9713785-5A patent/BR9713785A/pt unknown
- 1997-12-09 CA CA002274117A patent/CA2274117A1/en not_active Abandoned
- 1997-12-09 NZ NZ336028A patent/NZ336028A/en unknown
- 1997-12-09 CN CNA2004100324204A patent/CN1539824A/zh active Pending
- 1997-12-09 JP JP52867098A patent/JP2001507021A/ja not_active Ceased
- 1997-12-09 PT PT97950539T patent/PT946510E/pt unknown
- 1997-12-09 IL IL13053697A patent/IL130536A0/xx unknown
- 1997-12-09 AU AU53513/98A patent/AU738002B2/en not_active Ceased
- 1997-12-09 EP EP04002901A patent/EP1428821A1/de not_active Withdrawn
- 1997-12-09 RU RU99115746/04A patent/RU2193030C2/ru not_active IP Right Cessation
- 1997-12-09 EE EEP199900261A patent/EE03966B1/xx not_active IP Right Cessation
- 1997-12-09 EP EP97950539A patent/EP0946510B1/de not_active Expired - Lifetime
- 1997-12-09 CN CNB971808376A patent/CN1154635C/zh not_active Expired - Fee Related
- 1997-12-09 DE DE69729115T patent/DE69729115T2/de not_active Expired - Fee Related
- 1997-12-09 SK SK763-99A patent/SK283300B6/sk unknown
- 1997-12-09 ID IDW990536A patent/ID21662A/id unknown
- 1997-12-09 HU HU0000613A patent/HUP0000613A3/hu unknown
- 1997-12-09 DK DK97950539T patent/DK0946510T3/da active
- 1997-12-09 KR KR1019997005586A patent/KR20000069600A/ko not_active Ceased
- 1997-12-09 PL PL97334370A patent/PL188945B1/pl not_active IP Right Cessation
- 1997-12-09 AT AT97950539T patent/ATE266638T1/de not_active IP Right Cessation
- 1997-12-09 TR TR1999/01411T patent/TR199901411T2/xx unknown
- 1997-12-19 AR ARP970106076A patent/AR010378A1/es active IP Right Grant
- 1997-12-19 MY MYPI97006174A patent/MY132705A/en unknown
1999
- 1999-06-11 IS IS5078A patent/IS5078A/is unknown
- 1999-06-18 NO NO19993023A patent/NO313632B1/no unknown
2000
- 2000-08-25 US US09/645,565 patent/US6399635B1/en not_active Expired - Fee Related
2002
- 2002-04-15 US US10/121,683 patent/US6710179B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN1154635C (zh)	2004-06-23
EP0946510A1 (de)	1999-10-06
TR199901411T2 (xx)	1999-09-21
SE9604786D0 (sv)	1996-12-20
US6153626A (en)	2000-11-28
HK1023996A1 (en)	2000-09-29
MY132705A (en)	2007-10-31
AU5351398A (en)	1998-07-17
PL334370A1 (en)	2000-02-28
ZA9711049B (en)	1998-06-22
HUP0000613A3 (en)	2002-10-28
IS5078A (is)	1999-06-11
SK76399A3 (en)	2000-01-18
DK0946510T3 (da)	2004-08-09
DE69729115D1 (de)	2004-06-17
EP1428821A8 (de)	2005-01-26
BR9713785A (pt)	2000-02-08
US20030055045A1 (en)	2003-03-20
JP2001507021A (ja)	2001-05-29
ID21662A (id)	1999-07-08
PT946510E (pt)	2004-08-31
CZ220099A3 (cs)	1999-11-17
NO993023L (no)	1999-08-12
EE03966B1 (et)	2003-02-17
WO1998028270A1 (en)	1998-07-02
RU2193030C2 (ru)	2002-11-20
IL130536A0 (en)	2000-06-01
UA54481C2 (uk)	2003-03-17
NO313632B1 (no)	2002-11-04
DE69729115T2 (de)	2005-04-28
PL188945B1 (pl)	2005-05-31
SK283300B6 (sk)	2003-05-02
CN1241178A (zh)	2000-01-12
EE9900261A (et)	2000-02-15
US6710179B2 (en)	2004-03-23
HK1022910A1 (en)	2000-08-25
EP0946510B1 (de)	2004-05-12
CA2274117A1 (en)	1998-07-02
EP1428821A1 (de)	2004-06-16
NZ336028A (en)	2001-03-30
HUP0000613A2 (hu)	2000-09-28
NO993023D0 (no)	1999-06-18
AU738002B2 (en)	2001-09-06
ES2219783T3 (es)	2004-12-01
CN1539824A (zh)	2004-10-27
US6399635B1 (en)	2002-06-04
KR20000069600A (ko)	2000-11-25
AR010378A1 (es)	2000-06-07

Publication	Publication Date	Title
ATE296288T1 (de)	2005-06-15	Verbindungen mit analgetischer wirkung
ATE266638T1 (de)	2004-05-15	Verbindungen mit analgetischer wirkung
ATE223888T1 (de)	2002-09-15	1-dimethylaminomethyl-2-phenyl-cycloalk-2- enverbindungen mit analgetischer wirkung
ATE298739T1 (de)	2005-07-15	Calcylitische verbindungen
DE69721624D1 (de)	2003-06-12	Einspritzdüse
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