ATE113949T1 - Alpha-adrenergische rezeptorantagonisten. - Google Patents

Alpha-adrenergische rezeptorantagonisten.

Info

Publication number: ATE113949T1
Authority: AT; Austria
Prior art keywords: alpha; receptor antagonists; antagonists; adrenegic; adrenegic receptor
Prior art date: 1988-06-01

Application number

AT89305338T

Other languages

English (en)

Inventor

John Joseph Lafferty

Robert Michael Demarinis

Dinubhai Himatlal Shah

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-06-01

Filing date

1989-05-26

Publication date

1994-11-15

1989-05-26 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1994-11-15 Application granted granted Critical

1994-11-15 Publication of ATE113949T1 publication Critical patent/ATE113949T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Neurosurgery (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

AT89305338T 1988-06-01 1989-05-26 Alpha-adrenergische rezeptorantagonisten. ATE113949T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US20100488A	1988-06-01	1988-06-01

Publications (1)

Publication Number	Publication Date
ATE113949T1 true ATE113949T1 (de)	1994-11-15

Family

ID=22744083

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89305338T ATE113949T1 (de)	1988-06-01	1989-05-26	Alpha-adrenergische rezeptorantagonisten.

Country Status (13)

Country	Link
EP (1)	EP0344979B1 (de)
JP (1)	JPH03504607A (de)
KR (1)	KR900701797A (de)
CN (1)	CN1039810A (de)
AT (1)	ATE113949T1 (de)
AU (1)	AU629224B2 (de)
CA (1)	CA1320953C (de)
DE (1)	DE68919280T2 (de)
NZ (1)	NZ229300A (de)
PT (1)	PT90719B (de)
WO (1)	WO1989012054A1 (de)
ZA (1)	ZA894098B (de)
ZW (1)	ZW6789A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2107644A1 (en) *	1992-10-28	1994-04-29	David R. Magnin	.alpha.-phosphonosulfonae squalene synthetase inhibitors and methd
US5712396A (en) *	1992-10-28	1998-01-27	Magnin; David R.	α-phosphonosulfonate squalene synthetase inhibitors
FR2708612B1 (fr) *	1993-08-05	1996-03-01	Roussel Uclaf	Nouveaux dérivés bicycliques de l'imidazole, leur procédé de préparation, les nouveaux intermédiaires obtenus, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant.
US5447922A (en) *	1994-08-24	1995-09-05	Bristol-Myers Squibb Company	α-phosphonosulfinic squalene synthetase inhibitors
EP1939180A1 (de) *	2006-12-20	2008-07-02	sanofi-aventis	Heteroarylacrylamide und ihre Verwendung als Arzneimittel für die Stimulation der Expression der endothelialen NO-Synthase
US9556200B2 (en)	2012-03-06	2017-01-31	Takeda Pharmaceutical Company Limited	Tricyclic compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3856910A (en) *	1950-01-10	1974-12-24	Roussel Uclaf	Novel thienobenzazepines as anti-depressants
US3649644A (en) *	1969-08-08	1972-03-14	Warner Lambert Co	1 2 3 4 4a 5 6 6a-octahydrobenzofuro (3 2-c)indoles
BE795451A (fr) *	1972-02-23	1973-08-16	Pfizer	Agents hypoglycemiants aza indoliques tricycliques
US3950343A (en) *	1973-11-06	1976-04-13	Ayerst, Mckenna And Harrison Ltd.	Pyrroloisoquinoline derivatives
JPS57144286A (en) *	1981-03-02	1982-09-06	Takeda Chem Ind Ltd	Azepinoindole derivative and its preparation
US4833244A (en) *	1985-04-22	1989-05-23	Hoechst-Rouseel Pharmaceuticals Inc.	Ethanobenzazepines
DE3525564A1 (de) *	1985-07-15	1987-02-05	Schering Ag	Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4769368A (en) *	1986-02-10	1988-09-06	Smithkline Beckman Corporation	2,3,4,8,9,9A-Hexahydro-4-aryl-1H-indeno(1,7-CD)azepines
DE3630539A1 (de) *	1986-09-08	1988-03-10	Madaus & Co Dr	Derivate von 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonin (bzw. -1,4-benzoxazonin), verfahren zu ihrer herstellung und arzneimittel, die diese verbindung enthalten

1989
- 1989-05-26 CA CA000600795A patent/CA1320953C/en not_active Expired - Fee Related
- 1989-05-26 NZ NZ229300A patent/NZ229300A/xx unknown
- 1989-05-26 AT AT89305338T patent/ATE113949T1/de not_active IP Right Cessation
- 1989-05-26 DE DE68919280T patent/DE68919280T2/de not_active Expired - Fee Related
- 1989-05-26 EP EP89305338A patent/EP0344979B1/de not_active Expired - Lifetime
- 1989-05-29 ZW ZW67/89A patent/ZW6789A1/xx unknown
- 1989-05-30 ZA ZA894098A patent/ZA894098B/xx unknown
- 1989-05-31 AU AU38572/89A patent/AU629224B2/en not_active Ceased
- 1989-05-31 WO PCT/US1989/002396 patent/WO1989012054A1/en not_active Ceased
- 1989-05-31 JP JP1507325A patent/JPH03504607A/ja active Pending
- 1989-05-31 CN CN89103836A patent/CN1039810A/zh active Pending
- 1989-05-31 KR KR1019900700203A patent/KR900701797A/ko not_active Ceased
- 1989-06-01 PT PT90719A patent/PT90719B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0344979A3 (de)	1991-05-15
AU629224B2 (en)	1992-10-01
EP0344979B1 (de)	1994-11-09
EP0344979A2 (de)	1989-12-06
WO1989012054A1 (en)	1989-12-14
DE68919280T2 (de)	1995-03-23
KR900701797A (ko)	1990-12-04
ZA894098B (en)	1990-06-27
ZW6789A1 (en)	1989-08-30
NZ229300A (en)	1991-04-26
AU3857289A (en)	1990-01-05
DE68919280D1 (de)	1994-12-15
PT90719A (pt)	1989-12-29
CA1320953C (en)	1993-08-03
PT90719B (pt)	1994-11-30
CN1039810A (zh)	1990-02-21
JPH03504607A (ja)	1991-10-09

Publication	Publication Date	Title
DE69034103D1 (de)	2003-10-30	Imidazoalkensäure
SE8505112D0 (sv)	1985-10-29	Novel pharmacological compounds
ES2138977T3 (es)	2000-02-01	Agonistas muscarinicos.
ES2172580T3 (es)	2002-10-01	1,3-oxatiolanos sustituidos con propiedades antiviricas.
FI905481A0 (fi)	1990-11-05	Substituerade n-(imidazolyl) -alkylalaninderivat.
FI892222A0 (fi)	1989-05-09	Peptidalkoholer med antikoagulantverkan.
ATE113949T1 (de)	1994-11-15	Alpha-adrenergische rezeptorantagonisten.
FI881609A0 (fi)	1988-04-07	Dihydropyridinamider, foerfarande foer deras framstaellning och deras anvaendning i laekemedel.
ES2067541T3 (es)	1995-04-01	Mejoras en antagonistas de la serotonina y relacionadas con ellos.
FI891473A0 (fi)	1989-03-28	Menetelmä terapeuttisesti käyttökelpoisten 4-aryyli-4-piperidiinikarbinolien valmistamiseksi
ATE114310T1 (de)	1994-12-15	Alpha-adrenergische rezeptorantagonisten.
ES2044100T3 (es)	1994-01-01	Ciertas combinaciones de antagonistas del "paf" y antihistaminicos y metodos.
ATE109483T1 (de)	1994-08-15	Alpha-adrenergische rezeptorantagonisten.
EP0344980A3 (de)	1991-05-15	Alpha-adrenergische Rezeptorantagonisten
FI873145A0 (fi)	1987-07-16	Nya tetracykliska indolderivat.
ES2032838T3 (es)	1993-03-01	Un procedimiento para preparar derivados tetrahidropirido (1,2-a)indol.

Legal Events

Date	Code	Title	Description
1995-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties