ATE113599T1 - Heterozyklisch substituierte chinolincarbonsäure. - Google Patents
Heterozyklisch substituierte chinolincarbonsäure.Info
- Publication number
- ATE113599T1 ATE113599T1 AT88311797T AT88311797T ATE113599T1 AT E113599 T1 ATE113599 T1 AT E113599T1 AT 88311797 T AT88311797 T AT 88311797T AT 88311797 T AT88311797 T AT 88311797T AT E113599 T1 ATE113599 T1 AT E113599T1
- Authority
- AT
- Austria
- Prior art keywords
- heterocyclic
- quinolinecarbonic
- substitute
- acid
- heterocyclic substitute
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1987/003412 WO1989005643A1 (en) | 1987-12-18 | 1987-12-18 | Heterocyclic-substituted quinoline-carboxylic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE113599T1 true ATE113599T1 (de) | 1994-11-15 |
Family
ID=22202722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88311797T ATE113599T1 (de) | 1987-12-18 | 1988-12-14 | Heterozyklisch substituierte chinolincarbonsäure. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5037834A (de) |
| EP (1) | EP0321191B1 (de) |
| JP (1) | JPH0725757B2 (de) |
| KR (1) | KR900008568B1 (de) |
| AT (1) | ATE113599T1 (de) |
| AU (1) | AU600188B2 (de) |
| DE (1) | DE3852010T2 (de) |
| DK (1) | DK699788A (de) |
| ES (1) | ES2061695T3 (de) |
| FI (1) | FI90239C (de) |
| IE (1) | IE65732B1 (de) |
| IL (1) | IL88664A (de) |
| MY (1) | MY104072A (de) |
| NO (1) | NO178149C (de) |
| NZ (1) | NZ227357A (de) |
| PT (1) | PT89222B (de) |
| WO (1) | WO1989005643A1 (de) |
| ZA (1) | ZA889395B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2018667B3 (es) * | 1986-07-04 | 1991-05-01 | Chemie Linz Gmbh | Derivados del acido 4-qionolon-3-carboxilico, procedimiento para su obtencion y preparados farmaceuticos que los contienen. |
| US5093515A (en) * | 1987-08-14 | 1992-03-03 | Asahi Glass Company Ltd. | Fluorinated benzoyl compounds |
| ES2074047T3 (es) * | 1987-08-14 | 1995-09-01 | Asahi Glass Co Ltd | Compuestos de benzoilo fluorados. |
| US5214051A (en) * | 1989-08-01 | 1993-05-25 | Pfizer Inc. | Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed |
| KR910009333B1 (ko) * | 1989-10-23 | 1991-11-11 | 재단법인 한국화학연구소 | 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법 |
| KR910009330B1 (ko) * | 1989-10-23 | 1991-11-11 | 재단법인 한국화학연구소 | 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법 |
| DE4121214A1 (de) * | 1991-06-27 | 1993-01-14 | Bayer Ag | 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate |
| DE4342186A1 (de) * | 1993-12-10 | 1995-06-14 | Bayer Ag | Eintopfverfahren zur Herstellung von 3-Chinoloncarbonsäurederivaten |
| DE19652239A1 (de) * | 1996-12-16 | 1998-06-18 | Bayer Ag | Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen |
| US6608081B2 (en) * | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| US6855385B2 (en) * | 2000-05-31 | 2005-02-15 | Ttm Advanced Circuits, Inc. | PCB support plate for PCB via fill |
| CA2405532A1 (en) * | 2001-02-07 | 2002-08-22 | Ortho-Mcneil Pharmaceutical, Inc. | Pyridoarylphenyl oxazolidinone antibacterials, and related compositions and methods |
| MXPA05002004A (es) * | 2002-09-26 | 2005-04-28 | Pfizer | Derivados de pirazol. |
| CL2004000553A1 (es) * | 2003-03-20 | 2005-02-04 | Actelion Pharmaceuticals Ltd | Uso de compuestos derivados de guanidina como antagonistas del receptor de neuropeptido ff; compuestos derivados de guanidina; procedimientos de preparacion; y composicion farmaceutica que los comprende. |
| GB0610804D0 (en) * | 2006-05-31 | 2006-07-12 | Portela & Ca Sa | New crystal forms |
| ATE494289T1 (de) * | 2006-08-04 | 2011-01-15 | Merz Pharma Gmbh & Co Kgaa | Substituierte pyrazolopyrimidine, ein verfahren zu ihrer herstellung und ihre verwendung als medizin |
| WO2009072915A1 (en) * | 2007-12-05 | 2009-06-11 | Bial - Portela & Ca., S.A. | New salts and crystal forms |
| SI2751083T1 (en) * | 2011-08-31 | 2018-04-30 | Otsuka Pharmaceutical Co., Ltd. | Quinolone compound |
| US11357759B2 (en) | 2017-10-29 | 2022-06-14 | China Medical University | Composition including ADAM9 inhibitor and the use thereof |
| WO2022171139A1 (zh) * | 2021-02-10 | 2022-08-18 | 北京国鸿生物医药科技有限公司 | 一种巨环化合物、药物组合物以及其用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
| JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
| JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
| IE55898B1 (en) * | 1982-09-09 | 1991-02-14 | Warner Lambert Co | Antibacterial agents |
| US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| JPS59128383A (ja) * | 1982-12-29 | 1984-07-24 | Kanebo Ltd | 新規キノリンカルボン酸誘導体および該化合物を有効成分とする抗菌剤 |
| JPS59204194A (ja) * | 1983-05-09 | 1984-11-19 | Hokuriku Seiyaku Co Ltd | ７−ジアザビシクロアルカン置換−６，８−ジフオロ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体 |
| US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
| US4636506A (en) * | 1984-12-06 | 1987-01-13 | Pfizer, Inc. | 7-heterocyclic-1,4-dihydroquinolones |
| US4657913A (en) * | 1985-04-18 | 1987-04-14 | Warner-Lambert Company | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents |
| DE3519286A1 (de) * | 1985-05-30 | 1986-12-04 | Bayer Ag, 5090 Leverkusen | 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| IN166416B (de) * | 1985-09-18 | 1990-05-05 | Pfizer |
-
1987
- 1987-12-18 WO PCT/US1987/003412 patent/WO1989005643A1/en not_active Ceased
-
1988
- 1988-12-12 IL IL88664A patent/IL88664A/xx not_active IP Right Cessation
- 1988-12-14 ES ES88311797T patent/ES2061695T3/es not_active Expired - Lifetime
- 1988-12-14 EP EP88311797A patent/EP0321191B1/de not_active Expired - Lifetime
- 1988-12-14 AT AT88311797T patent/ATE113599T1/de not_active IP Right Cessation
- 1988-12-14 DE DE3852010T patent/DE3852010T2/de not_active Expired - Fee Related
- 1988-12-14 MY MYPI88001451A patent/MY104072A/en unknown
- 1988-12-15 PT PT89222A patent/PT89222B/pt not_active IP Right Cessation
- 1988-12-15 ZA ZA889395A patent/ZA889395B/xx unknown
- 1988-12-16 DK DK699788A patent/DK699788A/da not_active Application Discontinuation
- 1988-12-16 AU AU26987/88A patent/AU600188B2/en not_active Ceased
- 1988-12-16 IE IE376388A patent/IE65732B1/en not_active IP Right Cessation
- 1988-12-16 JP JP31934188A patent/JPH0725757B2/ja not_active Expired - Lifetime
- 1988-12-16 NZ NZ227357A patent/NZ227357A/en unknown
- 1988-12-17 KR KR1019880016841A patent/KR900008568B1/ko not_active Expired
-
1989
- 1989-08-01 US US07/435,496 patent/US5037834A/en not_active Expired - Lifetime
- 1989-08-17 NO NO893305A patent/NO178149C/no unknown
- 1989-08-17 FI FI893883A patent/FI90239C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK699788D0 (da) | 1988-12-16 |
| JPH01211587A (ja) | 1989-08-24 |
| DE3852010T2 (de) | 1995-03-09 |
| EP0321191B1 (de) | 1994-11-02 |
| WO1989005643A1 (en) | 1989-06-29 |
| NO178149B (no) | 1995-10-23 |
| FI893883A7 (fi) | 1989-08-17 |
| DE3852010D1 (de) | 1994-12-08 |
| FI90239C (fi) | 1994-01-10 |
| NO893305L (no) | 1989-10-17 |
| DK699788A (da) | 1989-08-11 |
| NO893305D0 (no) | 1989-08-17 |
| JPH0725757B2 (ja) | 1995-03-22 |
| EP0321191A2 (de) | 1989-06-21 |
| KR890009925A (ko) | 1989-08-04 |
| NO178149C (no) | 1996-01-31 |
| NZ227357A (en) | 1991-04-26 |
| IE65732B1 (en) | 1995-11-15 |
| IL88664A0 (en) | 1989-07-31 |
| FI90239B (fi) | 1993-09-30 |
| FI893883A0 (fi) | 1989-08-17 |
| PT89222B (pt) | 1994-11-30 |
| MY104072A (en) | 1993-11-30 |
| AU2698788A (en) | 1989-06-22 |
| IE883763L (en) | 1989-06-18 |
| AU600188B2 (en) | 1990-08-02 |
| IL88664A (en) | 1993-08-18 |
| EP0321191A3 (de) | 1991-02-27 |
| ES2061695T3 (es) | 1994-12-16 |
| US5037834A (en) | 1991-08-06 |
| KR900008568B1 (ko) | 1990-11-24 |
| PT89222A (pt) | 1989-12-29 |
| ZA889395B (en) | 1990-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |