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AR117002A2 - Proceso para la preparación de inhibidores de quinasa c-fms - Google Patents

Proceso para la preparación de inhibidores de quinasa c-fms

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Publication number
AR117002A2
AR117002A2 ARP190103246A ARP190103246A AR117002A2 AR 117002 A2 AR117002 A2 AR 117002A2 AR P190103246 A ARP190103246 A AR P190103246A AR P190103246 A ARP190103246 A AR P190103246A AR 117002 A2 AR117002 A2 AR 117002A2
Authority
AR
Argentina
Prior art keywords
preparation
kinase
formula
compound
fms inhibitors
Prior art date
Application number
ARP190103246A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of AR117002A2 publication Critical patent/AR117002A2/es

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Abstract

La presente se refiere a un proceso para la preparación de intermediarios útiles en la síntesis de inhibidores de proteína tirosina quinasa, más particularmente, inhibidores de quinasa c-fms. Reivindicación 1: Un proceso para la preparación de un compuesto de fórmula (1), estando el proceso caracterizado porque comprende: hacer reaccionar un compuesto de la fórmula (2) con NfsulphF, en presencia de DBU; en un solvente orgánico; a una temperatura de aproximadamente 0ºC a aproximadamente temperatura ambiente; para obtener el compuesto correspondiente de la fórmula (1).
ARP190103246A 2012-08-07 2019-11-06 Proceso para la preparación de inhibidores de quinasa c-fms AR117002A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261680446P 2012-08-07 2012-08-07

Publications (1)

Publication Number Publication Date
AR117002A2 true AR117002A2 (es) 2021-06-30

Family

ID=48980367

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP130102808A AR092070A1 (es) 2012-08-07 2013-08-07 Proceso para la preparacion de inhibidores de quinasa c-fms
ARP190103246A AR117002A2 (es) 2012-08-07 2019-11-06 Proceso para la preparación de inhibidores de quinasa c-fms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP130102808A AR092070A1 (es) 2012-08-07 2013-08-07 Proceso para la preparacion de inhibidores de quinasa c-fms

Country Status (12)

Country Link
US (2) US9029352B2 (es)
EP (2) EP3091006B1 (es)
JP (1) JP6290884B2 (es)
CN (2) CN104520295B (es)
AR (2) AR092070A1 (es)
AU (2) AU2013299926B2 (es)
ES (2) ES2607807T3 (es)
IN (1) IN2015DN00660A (es)
JO (2) JOP20180012A1 (es)
TW (2) TWI646090B (es)
UY (1) UY34972A (es)
WO (1) WO2014025679A1 (es)

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CN106459087B (zh) * 2014-02-18 2019-04-09 第一三共株式会社 活化的凝血因子X (FXa)抑制剂的制备方法
TW201811326A (zh) 2016-07-18 2018-04-01 比利時商健生藥品公司 ４－氰基－ｎ－（２－（４，４－二甲基環己－１－烯－１－基）－６－（２，２，６，６－四甲基四氫－２ｈ－哌喃－４－基）吡啶－３－基）－１ｈ－咪唑－２－甲醯胺之鹽形式
TWI752980B (zh) 2016-07-18 2022-01-21 比利時商健生藥品公司 4-氰基-n-(2-(4,4-二甲基環己-1-烯-1-基)-6-(2,2,6,6-四甲基四氫-2h-哌喃-4-基)吡啶-3-基)-1h-咪唑-2-甲醯胺之晶型
JP6831558B2 (ja) * 2016-08-23 2021-02-17 株式会社Ｈｂｃフナト 脳機能改善組成物
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