AR096135A1 - Derivados de la quinolona - Google Patents
Derivados de la quinolonaInfo
- Publication number
- AR096135A1 AR096135A1 ARP140101763A ARP140101763A AR096135A1 AR 096135 A1 AR096135 A1 AR 096135A1 AR P140101763 A ARP140101763 A AR P140101763A AR P140101763 A ARP140101763 A AR P140101763A AR 096135 A1 AR096135 A1 AR 096135A1
- Authority
- AR
- Argentina
- Prior art keywords
- diyl
- nitrogen atoms
- group
- quinolona
- derivatives
- Prior art date
Links
- -1 cyclohexane-1,4-diyl Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000006555 (C3-C5) cycloalkyl group Chemical group 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Epidemiology (AREA)
Abstract
Composiciones farmacéuticas que las contienen y a los usos de estos compuestos en la elaboración de medicamentos para el tratamiento de infecciones bacterianas. Reivindicación 1: Un compuesto de la fórmula (1), donde R¹ representa alquilo C₁₋₃ o cicloalquilo C₃₋₅; U representa CH o N; V representa O ó S; y A representa un grupo de unión que consta de un grupo de cadena recta saturado de 1, 2 ó 3 miembros que se une a -o está interrumpido por- un grupo cíclico de 6 miembros que se selecciona de ciclohexan-1,4-diilo, piperidin-1,4-diilo y piperazin-1,4-diilo; donde dicho grupo de unión contiene un total de entre dos y tres átomos de nitrógeno, donde dichos átomos de nitrógeno se separan entre sí por al menos dos átomos de carbono; o una de sus sales farmacéuticamente aceptables.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2013053472 | 2013-05-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR096135A1 true AR096135A1 (es) | 2015-12-09 |
Family
ID=50819763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140101763A AR096135A1 (es) | 2013-05-02 | 2014-04-29 | Derivados de la quinolona |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9540399B2 (es) |
| EP (1) | EP2991992B1 (es) |
| JP (1) | JP6337095B2 (es) |
| KR (1) | KR20160003244A (es) |
| CN (1) | CN105189520B (es) |
| AR (1) | AR096135A1 (es) |
| AU (1) | AU2014261101A1 (es) |
| CA (1) | CA2910042A1 (es) |
| ES (1) | ES2692652T3 (es) |
| MX (1) | MX2015015251A (es) |
| RU (1) | RU2015151456A (es) |
| TW (1) | TW201522348A (es) |
| WO (1) | WO2014178008A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2018001075A (es) * | 2015-07-28 | 2019-04-15 | Vyome Therapeutics Ltd | Agentes terapeuticos y profilacticos antibacterianos. |
| RU2636751C1 (ru) * | 2016-11-02 | 2017-12-01 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Антибактериальные средства на основе производных ципрофлоксацина |
| TW201833120A (zh) | 2017-02-17 | 2018-09-16 | 瑞士商愛杜西亞製藥有限公司 | 芳基噁唑啶酮抗生素化合物 |
| WO2021009212A1 (en) | 2019-07-16 | 2021-01-21 | Idorsia Pharmaceuticals Ltd | Antibacterial quinolone derivatives |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5649382A (en) | 1979-09-28 | 1981-05-02 | Dainippon Pharmaceut Co Ltd | 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt |
| DE3508816A1 (de) | 1985-01-10 | 1986-07-10 | Bayer Ag, 5090 Leverkusen | 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren |
| EP0775145A1 (en) | 1994-08-02 | 1997-05-28 | The Procter & Gamble Company | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds |
| JPH09323932A (ja) * | 1996-01-31 | 1997-12-16 | Sankyo Co Ltd | エイズ治療剤又は予防剤 |
| GB0101577D0 (en) | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| WO2002102792A1 (en) | 2001-06-15 | 2002-12-27 | Microbiotix, Inc. | Novel heterocyclic antibacterial compounds |
| US6777420B2 (en) | 2001-06-15 | 2004-08-17 | Microbiotix, Inc. | Heterocyclic antibacterial compounds |
| TW200507841A (en) | 2003-03-27 | 2005-03-01 | Glaxo Group Ltd | Antibacterial agents |
| CA2572442A1 (fr) * | 2004-07-30 | 2006-03-09 | Palumed S.A. | Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien |
| WO2006081289A2 (en) | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
| CA2650683A1 (en) | 2006-04-28 | 2007-11-08 | Shionogi & Co., Ltd. | Amine derivative having npy y5 receptor antagonist activity |
| US20100256124A1 (en) | 2006-06-09 | 2010-10-07 | David Thomas Davies | Substituted 1-Methyl-1H-Quinolin-2-Ones And 1-Methyl-1H-1,5-Naphthyridin-2-Ones As Antibacterials |
| WO2008143343A1 (ja) | 2007-05-24 | 2008-11-27 | Kyorin Pharmaceutical Co., Ltd. | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| US7884099B2 (en) | 2007-11-16 | 2011-02-08 | Cumbre Ip Ventures, L.P. | Quinolone carboxylic acid-substituted rifamycin derivatives |
| AU2009282478A1 (en) | 2008-08-11 | 2010-02-18 | Biorelix,Inc. | Flavin derivatives |
| GB0815962D0 (en) | 2008-09-02 | 2008-10-08 | Merlion Pharmaceuticals Pte Ltd | Hybrid antibacterial compounds and their use |
| WO2010045987A1 (en) | 2008-10-23 | 2010-04-29 | Glaxo Group Limited | Substituted (aza) -1-methyl-1h-quin0lin-2-0nes as antibacterials |
| TW201022279A (en) * | 2008-11-14 | 2010-06-16 | Astrazeneca Ab | Chemical compounds |
| WO2010084152A1 (en) | 2009-01-21 | 2010-07-29 | Basilea Pharmaceutica Ag | Novel bicyclic antibiotics |
| WO2011034971A1 (en) | 2009-09-15 | 2011-03-24 | Designmedix, Inc. | Modified fluoroquinolone compounds and methods of using the same |
| TW201121965A (en) | 2009-09-28 | 2011-07-01 | Lg Life Sciences Ltd | Use of a quinolone derivative containing 7-(4-aminomethyl-3-oxime)pyrrolidine group that is capable of inducing granulocyte colony stimulating factor for treatment of neutropenia and recovery of hematopoiesis |
| WO2011094260A2 (en) | 2010-01-26 | 2011-08-04 | Stc. Unm | Novel bifunctional metnase/intnase inhibitors and related compositions and methods of treatment of cancer |
| JP5959537B2 (ja) | 2011-01-28 | 2016-08-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換ピリジニル−ピリミジン及び医薬としてのその使用 |
| AU2012303954B2 (en) | 2011-08-31 | 2017-06-22 | Otsuka Pharmaceutical Co., Ltd. | Quinolone compound |
| EP2776431B1 (en) | 2011-11-08 | 2016-05-04 | Actelion Pharmaceuticals Ltd. | 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives |
| US20150126519A1 (en) | 2012-03-20 | 2015-05-07 | Fred Hutchinson Cancer Research Center | Antibiotic compounds and compositions, and methods for identification thereof |
-
2014
- 2014-04-29 AR ARP140101763A patent/AR096135A1/es unknown
- 2014-04-30 CN CN201480024178.8A patent/CN105189520B/zh not_active Expired - Fee Related
- 2014-04-30 JP JP2016511157A patent/JP6337095B2/ja not_active Expired - Fee Related
- 2014-04-30 EP EP14726420.4A patent/EP2991992B1/en not_active Not-in-force
- 2014-04-30 ES ES14726420.4T patent/ES2692652T3/es active Active
- 2014-04-30 KR KR1020157034265A patent/KR20160003244A/ko not_active Ceased
- 2014-04-30 RU RU2015151456A patent/RU2015151456A/ru unknown
- 2014-04-30 CA CA2910042A patent/CA2910042A1/en not_active Abandoned
- 2014-04-30 TW TW103115665A patent/TW201522348A/zh unknown
- 2014-04-30 AU AU2014261101A patent/AU2014261101A1/en not_active Abandoned
- 2014-04-30 WO PCT/IB2014/061099 patent/WO2014178008A1/en not_active Ceased
- 2014-04-30 MX MX2015015251A patent/MX2015015251A/es unknown
- 2014-04-30 US US14/888,581 patent/US9540399B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2692652T3 (es) | 2018-12-04 |
| CA2910042A1 (en) | 2014-11-06 |
| AU2014261101A1 (en) | 2015-12-17 |
| RU2015151456A (ru) | 2017-06-07 |
| EP2991992A1 (en) | 2016-03-09 |
| CN105189520B (zh) | 2017-10-10 |
| US9540399B2 (en) | 2017-01-10 |
| WO2014178008A1 (en) | 2014-11-06 |
| JP6337095B2 (ja) | 2018-06-06 |
| CN105189520A (zh) | 2015-12-23 |
| KR20160003244A (ko) | 2016-01-08 |
| US20160060276A1 (en) | 2016-03-03 |
| EP2991992B1 (en) | 2018-07-25 |
| JP2016517880A (ja) | 2016-06-20 |
| MX2015015251A (es) | 2016-02-09 |
| TW201522348A (zh) | 2015-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |