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AR075927A1 - Procedimiento para la produccion de glioxilato mediante fermentacion - Google Patents

Procedimiento para la produccion de glioxilato mediante fermentacion

Info

Publication number
AR075927A1
AR075927A1 ARP100100930A ARP100100930A AR075927A1 AR 075927 A1 AR075927 A1 AR 075927A1 AR P100100930 A ARP100100930 A AR P100100930A AR P100100930 A ARP100100930 A AR P100100930A AR 075927 A1 AR075927 A1 AR 075927A1
Authority
AR
Argentina
Prior art keywords
procedure
production
glioxylate
fermentation
recombinant microorganism
Prior art date
Application number
ARP100100930A
Other languages
English (en)
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of AR075927A1 publication Critical patent/AR075927A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Procedimiento para la bioconversion de una fuente de carbono fermentable en glioxilato mediante un microorganismo recombinante con modificaciones genéticas como por ejemplo deltaldhA, deltamgsA, deltaarcA y deltalldP, deltaglcA, deltayjcG y la combinacion de ellas que permite una produccion con mayor rendimiento, valoracion y productividad. Se provee además el microorganismo recombinante que pertenece al género Escherichia.
ARP100100930A 2009-03-24 2010-03-23 Procedimiento para la produccion de glioxilato mediante fermentacion AR075927A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16271209P 2009-03-24 2009-03-24
EP09155971A EP2233562A1 (en) 2009-03-24 2009-03-24 Method for producing high amount of glycolic acid by fermentation

Publications (1)

Publication Number Publication Date
AR075927A1 true AR075927A1 (es) 2011-05-04

Family

ID=40671604

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100100930A AR075927A1 (es) 2009-03-24 2010-03-23 Procedimiento para la produccion de glioxilato mediante fermentacion

Country Status (12)

Country Link
US (1) US8945888B2 (es)
EP (2) EP2233562A1 (es)
JP (1) JP5800795B2 (es)
KR (1) KR101764933B1 (es)
CN (1) CN102365357A (es)
AR (1) AR075927A1 (es)
BR (1) BRPI1012693B1 (es)
CA (1) CA2754949C (es)
ES (1) ES2593084T3 (es)
MX (1) MX2011010024A (es)
MY (1) MY164623A (es)
WO (1) WO2010108909A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2480679A2 (en) * 2009-09-25 2012-08-01 Roquette Frères Fermentation process for producing glycolic acid
WO2011083059A1 (en) * 2010-01-06 2011-07-14 Universiteit Gent Bacterial mutants and uses thereof in protein production
US9121043B2 (en) 2010-06-15 2015-09-01 Metabolic Explorer Method for producing glycolic acid using an inducible promoter
US20130210097A1 (en) * 2010-08-27 2013-08-15 Metabolic Explorer Glycolic acid fermentative production with a modified microorganism
FI125136B (en) 2011-10-04 2015-06-15 Teknologian Tutkimuskeskus Vtt Oy Eukaryotic cells and a method for preparing glycolic acid
AU2012351501B2 (en) * 2011-12-16 2018-06-14 Inbiose N.V. Mutant microorganisms to synthesize colanic acid, mannosylated and/or fucosylated oligosaccharides
HK1220484A1 (zh) 2013-03-14 2017-05-05 President And Fellows Of Harvard College 用於选择从基因改造微生物库检测和优化生产代谢物的方法
JP2016163540A (ja) * 2013-07-09 2016-09-08 味の素株式会社 有用物質の製造方法
FR3028529B1 (fr) 2014-11-19 2016-12-30 Inst Nat De La Rech Agronomique Inra Procede de production d'au moins un metabolite d'interet par transformation d'un pentose dans un microorganisme
FI20155412A (fi) * 2015-05-29 2016-11-30 Teknologian Tutkimuskeskus Vtt Oy Sokerien suora konversio glykolihapoksi
WO2017059236A1 (en) * 2015-10-02 2017-04-06 Massachusetts Institute Of Technology Microbial production of renewable glycolate
CN106011185B (zh) * 2016-06-27 2019-12-17 江南大学 一种无基因敲除提高大肠杆菌中乙醇酸产率的方法
EP3481851B1 (en) 2016-07-08 2021-11-24 Metabolic Explorer Method for the fermentative production of molecules of interest by microorganisms comprising genes coding sugar phosphotransferase system (pts)
EP3354742A1 (en) 2017-01-26 2018-08-01 Metabolic Explorer Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid
CN118956710A (zh) 2017-09-07 2024-11-15 多伦多大学管理委员会 从乙二醇生产乙醇酸盐以及相关微生物工程改造
US11293039B2 (en) 2017-10-02 2022-04-05 Metabolic Explorer Method for producing organic acid salts from fermentation broth
WO2020152342A1 (en) 2019-01-24 2020-07-30 Photanol B.V. A process for the bioproduction of glycolate
WO2020163935A1 (en) 2019-02-15 2020-08-20 Braskem S.A. Microorganisms and methods for the production of glycolic acid and glycine via reverse glyoxylate shunt
BR112021015719A2 (pt) * 2019-02-20 2021-12-14 Braskem Sa Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses
JP7463388B2 (ja) * 2019-02-20 2024-04-08 ブラスケム エス.エー. ペントース糖およびヘキソース糖のための分解経路
CN113025506B (zh) * 2019-12-24 2022-12-09 中国科学院天津工业生物技术研究所 一种生产乙醇的重组丝状真菌及其构建和应用
WO2022133719A1 (en) * 2020-12-22 2022-06-30 Rhodia Operations Method for producing glycolic acid
KR102558672B1 (ko) * 2022-05-17 2023-07-25 주식회사 엑티브온 1,3-프로판디올 생산 변이 미생물 및 이를 이용한 1,3-프로판디올의 생산 방법
WO2024084032A1 (de) 2022-10-20 2024-04-25 Annikki Gmbh Verfahren zur herstellung einer wässerigen lösung enthaltend ein alkalisalz der glycolsäure und der milchsäure
EP4631928A1 (en) 2024-04-10 2025-10-15 Metabolic Explorer Method of purification of glycolic acid, composition and use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4637372B2 (ja) 1999-05-21 2011-02-23 カーギル ダウ エルエルシー 有機生成物の合成方法および合成材料
AU2003205041A1 (en) 2002-07-12 2004-01-29 Ajinomoto Co., Inc. Method for producing target substance by fermentation
JP4592418B2 (ja) 2002-10-04 2010-12-01 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 高収率での1,3−プロパンジオールの生物生産のための方法
US7262046B2 (en) 2004-08-09 2007-08-28 Rice University Aerobic succinate production in bacteria
CN101023178A (zh) * 2004-09-17 2007-08-22 莱斯大学 高琥珀酸产出细菌
US20070116852A1 (en) 2005-11-22 2007-05-24 Josef Schnatmann Cattle feed preparation
WO2007140816A1 (en) 2006-06-09 2007-12-13 Metabolic Explorer Glycolic acid production by fermentation from renewable resources
KR100780324B1 (ko) 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
DK2109681T3 (en) 2007-03-23 2014-12-08 Metabolic Explorer Sa NEW MICROORGANISMS FOR THE PREPARATION OF 1,2-PROPANDIOL OBTAINED BY A COMBINATION OF EVOLUTION AND RATIONAL DESIGN
EP2139985A1 (en) 2007-03-23 2010-01-06 Metabolic Explorer Metabolically engineered microorganism useful for the production of 1,2-propanediol

Also Published As

Publication number Publication date
CN102365357A (zh) 2012-02-29
KR101764933B1 (ko) 2017-08-03
WO2010108909A1 (en) 2010-09-30
BRPI1012693A2 (pt) 2015-09-15
JP2012521206A (ja) 2012-09-13
BRPI1012693B1 (pt) 2019-11-12
KR20120002593A (ko) 2012-01-06
CA2754949C (en) 2021-07-06
US8945888B2 (en) 2015-02-03
EP2411502A1 (en) 2012-02-01
MX2011010024A (es) 2011-10-10
US20120315682A1 (en) 2012-12-13
JP5800795B2 (ja) 2015-10-28
ES2593084T3 (es) 2016-12-05
EP2233562A1 (en) 2010-09-29
EP2411502B1 (en) 2016-08-03
MY164623A (en) 2018-01-30
CA2754949A1 (en) 2010-09-30

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