AR067993A1 - Forma galenica divisible que permite una liberacion modificada del principio activo - Google Patents
Forma galenica divisible que permite una liberacion modificada del principio activoInfo
- Publication number
- AR067993A1 AR067993A1 ARP080103637A ARP080103637A AR067993A1 AR 067993 A1 AR067993 A1 AR 067993A1 AR P080103637 A ARP080103637 A AR P080103637A AR P080103637 A ARP080103637 A AR P080103637A AR 067993 A1 AR067993 A1 AR 067993A1
- Authority
- AR
- Argentina
- Prior art keywords
- tablet
- divisible
- modified release
- allows
- active principle
- Prior art date
Links
- 239000003826 tablet Substances 0.000 abstract 7
- 239000011230 binding agent Substances 0.000 abstract 2
- 239000001913 cellulose Substances 0.000 abstract 2
- 229920002678 cellulose Polymers 0.000 abstract 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 2
- LQIAZOCLNBBZQK-UHFFFAOYSA-N 1-(1,2-Diphosphanylethyl)pyrrolidin-2-one Chemical compound PCC(P)N1CCCC1=O LQIAZOCLNBBZQK-UHFFFAOYSA-N 0.000 abstract 1
- 229920002774 Maltodextrin Polymers 0.000 abstract 1
- 239000005913 Maltodextrin Substances 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000008119 colloidal silica Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical group 0.000 abstract 1
- 229940035034 maltodextrin Drugs 0.000 abstract 1
- 239000007912 modified release tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Reivindicacion 1: Un comprimido divisible de liberacion modificada que comprende un principio activo, un derivado de celulosa y un aglutinante, de tal modo que el comprimido no subdividido y una fraccion de dicho comprimido obtenida por subdivision tienen un perfil de disolucion similar. Reivindicacion 2: El comprimido segun la reivindicacion 1, caracterizado porque la sustancia activa es la glicazida. Reivindicacion 4: El comprimido segun una de las reivindicaciones 1 a 3, caracterizado porque el derivado de celulosa es la hidroxipropilmetilcelulosa de baja viscosidad. Reivindicacion 5: El comprimido segun una de las reivindicaciones 1 a 4, caracterizado porque el aglutinante es la maltodextrina, la polividona o una hidroxipropilmetilcelulosa de muy baja viscosidad. Reivindicacion 6: El comprimido segun una de las reivindicaciones 1 a 5, caracterizado porque el comprimido comprende un hidrofilizante y con preferencia el hidrofilizante es la sílice coloidal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0801561A FR2928836B1 (fr) | 2008-03-21 | 2008-03-21 | Forme galenique secable permettant une liberation modifiee du principe actif |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR067993A1 true AR067993A1 (es) | 2009-10-28 |
Family
ID=39796790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080103637A AR067993A1 (es) | 2008-03-21 | 2008-08-21 | Forma galenica divisible que permite una liberacion modificada del principio activo |
Country Status (35)
| Country | Link |
|---|---|
| US (3) | US20090238870A1 (es) |
| EP (2) | EP2103302A1 (es) |
| JP (2) | JP5231906B2 (es) |
| KR (3) | KR20090101048A (es) |
| CN (1) | CN101347414B (es) |
| AP (1) | AP2729A (es) |
| AR (1) | AR067993A1 (es) |
| AU (1) | AU2008207680B8 (es) |
| CA (1) | CA2629670C (es) |
| CL (1) | CL2008002486A1 (es) |
| CO (1) | CO6020017A1 (es) |
| CR (2) | CR10317A (es) |
| CU (1) | CU23970B1 (es) |
| EA (1) | EA200801862A1 (es) |
| EC (1) | ECSP088727A (es) |
| FR (1) | FR2928836B1 (es) |
| GT (1) | GT200800163A (es) |
| HN (1) | HN2008001466A (es) |
| IL (1) | IL193611A0 (es) |
| JO (1) | JO3052B1 (es) |
| MA (1) | MA31218B1 (es) |
| ME (1) | ME01031B (es) |
| MX (1) | MX2008011579A (es) |
| MY (1) | MY150660A (es) |
| NI (1) | NI200800256A (es) |
| NZ (1) | NZ570715A (es) |
| PE (1) | PE20090991A1 (es) |
| SA (1) | SA08290555B1 (es) |
| SG (1) | SG155819A1 (es) |
| SV (1) | SV2008003023A (es) |
| TW (1) | TWI396561B (es) |
| UA (1) | UA86731C2 (es) |
| UY (1) | UY31307A1 (es) |
| WO (1) | WO2009125087A1 (es) |
| ZA (1) | ZA200807354B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1940467B1 (en) | 2005-09-09 | 2016-11-02 | Paladin Labs Inc. | Sustained drug release composition |
| US20070160960A1 (en) * | 2005-10-21 | 2007-07-12 | Laser Shot, Inc. | System and method for calculating a projectile impact coordinates |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| DE102010015123A1 (de) | 2010-04-16 | 2011-10-20 | Sanofi-Aventis Deutschland Gmbh | Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TR201103946A1 (tr) | 2011-04-22 | 2012-11-21 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Kontrollü salım sağlayan gliklazid formülasyonları. |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| ITFI20130184A1 (it) | 2013-08-01 | 2015-02-02 | Valpharma Internat S P A | Una formulazione farmaceutica di gliclazide a rilascio modificato, somministrabile per via orale, e suo metodo di produzione. |
| CN106892856A (zh) * | 2017-02-06 | 2017-06-27 | 山东科源制药股份有限公司 | 一种格列齐特粗品重结晶的制备方法 |
| ES3010208T3 (en) | 2020-03-16 | 2025-04-01 | Gruenenthal Gmbh | Scored tablet comprising tapentadol |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH648754A5 (en) * | 1979-08-16 | 1985-04-15 | Ciba Geigy Ag | Pharmaceutical slow release tablet |
| US4353887A (en) * | 1979-08-16 | 1982-10-12 | Ciba-Geigy Corporation | Divisible tablet having controlled and delayed release of the active substance |
| US4851230A (en) * | 1983-04-07 | 1989-07-25 | Bristol-Myers Company | Capsule shaped tablets |
| GB8724763D0 (en) * | 1987-10-22 | 1987-11-25 | Aps Research Ltd | Sustained-release formulations |
| US5126145A (en) * | 1989-04-13 | 1992-06-30 | Upsher Smith Laboratories Inc | Controlled release tablet containing water soluble medicament |
| JPH069375A (ja) * | 1992-04-10 | 1994-01-18 | Takeda Chem Ind Ltd | 分割可能な連結錠剤 |
| DE4229085C2 (de) * | 1992-09-01 | 1996-07-11 | Boehringer Mannheim Gmbh | Längliche, teilbare Tablette |
| US5859037A (en) * | 1997-02-19 | 1999-01-12 | Warner-Lambert Company | Sulfonylurea-glitazone combinations for diabetes |
| WO1999029314A1 (en) * | 1997-12-08 | 1999-06-17 | Bristol-Myers Squibb Company | Novel salts of metformin and method |
| ID26082A (id) * | 1998-03-19 | 2000-11-23 | Briston Myers Squib Company | Sistem pengiriman lepas terkendali dwifasa untuk zat-zat farmasi kelarutan tinggi dan metodenya |
| JP2006052230A (ja) * | 1998-04-03 | 2006-02-23 | Kyowa Hakko Kogyo Co Ltd | 分割錠剤及びプレススルーパック |
| ATE387905T1 (de) * | 1998-04-03 | 2008-03-15 | Kyowa Hakko Kogyo Kk | Teilbare tablette und durchdrückpackung |
| AP1243A (en) * | 1999-02-01 | 2004-02-02 | Servier Lab | Core tablet for controlled release of gliclazide after oral administration. |
| PL198797B1 (pl) * | 1999-03-31 | 2008-07-31 | Janssen Pharmaceutica Nv | Zastosowanie wstępnie żelowanej skrobi |
| US6878749B2 (en) * | 1999-09-17 | 2005-04-12 | Novartis Ag | Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes |
| DE10117208A1 (de) * | 2001-04-06 | 2002-10-10 | Wolff Walsrode Ag | Verfahren zur Herstellung von niederviskosen, wässrigen Celluloseetherlösungen |
| CN1294908C (zh) * | 2003-06-08 | 2007-01-17 | 安徽省医药科技实业公司 | 口服格列齐特缓释制剂 |
| CA2563325C (en) * | 2004-04-29 | 2010-06-22 | Lotus Pharmaceutical Co., Ltd. | Oral modified-release lozenges and their preparation method |
| US7622137B2 (en) * | 2004-05-21 | 2009-11-24 | Accu-Break Technologies, Inc. | Dosage forms contained within a capsule or sachet |
| EP1827453A1 (en) * | 2004-12-06 | 2007-09-05 | Themis Laboratories Private Limited | Sulfonylurea compositions and a process for its preparation |
| DE102005014141B4 (de) * | 2005-03-23 | 2006-12-21 | Hennig Arzneimittel Gmbh & Co. Kg | Tablettenförmige Retardzubereitung gegen Schwindel |
| UA100966C2 (ru) * | 2005-04-08 | 2013-02-25 | Эбботт Леборетриз | Фармацевтическая композиция на основе 2-[4-(4-хлорбензоил)фенокси]-2-метилпропионовой кислоты и ее солей |
| EP3205337A1 (en) * | 2005-08-18 | 2017-08-16 | Teijin Pharma Limited | Formulation having accurate dose-dividing function |
| JP5046501B2 (ja) * | 2005-08-18 | 2012-10-10 | 帝人ファーマ株式会社 | 複数の薬物を分離して保持する錠剤 |
| EP1940467B1 (en) * | 2005-09-09 | 2016-11-02 | Paladin Labs Inc. | Sustained drug release composition |
| JOP20180109A1 (ar) * | 2005-09-29 | 2019-01-30 | Novartis Ag | تركيبة جديدة |
| NZ574954A (en) * | 2006-08-10 | 2011-11-25 | Takeda Pharmaceutical | Pharmaceutical composition comprising 2-ethoxy-1-{ [2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl} -1H-benzimidazole-7-carboxylic acid |
| WO2008062470A2 (en) * | 2006-10-19 | 2008-05-29 | Torrent Pharmaceuticals Limited | Stabilized controlled release dosage form of gliclazide |
| JP2008208078A (ja) * | 2007-02-27 | 2008-09-11 | Takada Seiyaku Kk | 分割錠剤 |
-
2008
- 2008-03-21 FR FR0801561A patent/FR2928836B1/fr active Active
- 2008-04-24 CA CA2629670A patent/CA2629670C/fr not_active Expired - Fee Related
- 2008-08-18 EP EP08290778A patent/EP2103302A1/fr not_active Withdrawn
- 2008-08-18 EP EP15191226.8A patent/EP3025706A1/fr not_active Withdrawn
- 2008-08-20 UA UAA200810556A patent/UA86731C2/ru unknown
- 2008-08-21 GT GT200800163A patent/GT200800163A/es unknown
- 2008-08-21 SG SG200806219-2A patent/SG155819A1/en unknown
- 2008-08-21 MY MYPI20083200 patent/MY150660A/en unknown
- 2008-08-21 AR ARP080103637A patent/AR067993A1/es not_active Application Discontinuation
- 2008-08-21 IL IL193611A patent/IL193611A0/en active IP Right Grant
- 2008-08-22 US US12/229,418 patent/US20090238870A1/en not_active Abandoned
- 2008-08-22 UY UY31307A patent/UY31307A1/es not_active Application Discontinuation
- 2008-08-22 NZ NZ570715A patent/NZ570715A/en unknown
- 2008-08-22 PE PE2008001421A patent/PE20090991A1/es active IP Right Grant
- 2008-08-22 CL CL2008002486A patent/CL2008002486A1/es unknown
- 2008-09-02 AU AU2008207680A patent/AU2008207680B8/en active Active
- 2008-09-02 TW TW097133651A patent/TWI396561B/zh active
- 2008-09-03 SA SA08290555A patent/SA08290555B1/ar unknown
- 2008-09-04 CN CN2008102137696A patent/CN101347414B/zh active Active
- 2008-09-08 JP JP2008229452A patent/JP5231906B2/ja active Active
- 2008-09-09 EC EC2008008727A patent/ECSP088727A/es unknown
- 2008-09-10 MX MX2008011579A patent/MX2008011579A/es active IP Right Grant
- 2008-09-10 SV SV2008003023A patent/SV2008003023A/es unknown
- 2008-09-11 CO CO08095780A patent/CO6020017A1/es not_active Application Discontinuation
- 2008-09-11 JO JOP/2008/0408A patent/JO3052B1/ar active
- 2008-09-15 AP AP2008004614A patent/AP2729A/xx active
- 2008-09-19 EA EA200801862A patent/EA200801862A1/ru unknown
- 2008-09-19 HN HN2008001466A patent/HN2008001466A/es unknown
- 2008-09-22 KR KR1020080092747A patent/KR20090101048A/ko not_active Ceased
- 2008-09-23 CU CU2008000179A patent/CU23970B1/es active IP Right Grant
- 2008-09-24 CR CR10317A patent/CR10317A/es unknown
- 2008-09-25 NI NI200800256A patent/NI200800256A/es unknown
- 2008-10-01 ZA ZA200807354A patent/ZA200807354B/xx unknown
- 2008-10-13 MA MA31286A patent/MA31218B1/fr unknown
-
2009
- 2009-03-20 WO PCT/FR2009/000295 patent/WO2009125087A1/fr not_active Ceased
- 2009-03-20 ME MEP-2010-154A patent/ME01031B/me unknown
-
2010
- 2010-05-12 JP JP2010109928A patent/JP2010209103A/ja active Pending
-
2011
- 2011-09-19 KR KR1020110094146A patent/KR101693189B1/ko active Active
-
2013
- 2013-06-12 US US13/916,029 patent/US20130295176A1/en not_active Abandoned
-
2014
- 2014-03-12 US US14/206,063 patent/US20140221449A1/en not_active Abandoned
- 2014-07-10 CR CR20140334A patent/CR20140334A/es unknown
-
2015
- 2015-01-12 KR KR20150004248A patent/KR20150035829A/ko not_active Ceased
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