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CY1115961T1 - Ανυδρη μορφη κρυσταλλικης μηλεϊνικης ορβεπιταντης (orvepitant maleate) - Google Patents

Ανυδρη μορφη κρυσταλλικης μηλεϊνικης ορβεπιταντης (orvepitant maleate)

Info

Publication number
CY1115961T1
CY1115961T1 CY20151100093T CY151100093T CY1115961T1 CY 1115961 T1 CY1115961 T1 CY 1115961T1 CY 20151100093 T CY20151100093 T CY 20151100093T CY 151100093 T CY151100093 T CY 151100093T CY 1115961 T1 CY1115961 T1 CY 1115961T1
Authority
CY
Cyprus
Prior art keywords
maline
crystal
orvepitant maleate
anhydrated
anhydrated form
Prior art date
Application number
CY20151100093T
Other languages
English (en)
Inventor
Stefania Beato
Franco Sartor
Ian Philip Steeples
Original Assignee
Nerre Therapeutics Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerre Therapeutics Limited filed Critical Nerre Therapeutics Limited
Publication of CY1115961T1 publication Critical patent/CY1115961T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Liquid Crystal Substances (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)

Abstract

Η εφεύρεση αφορά άνυδρη κρυσταλλική μηλεϊνική ορβεπιτάντη (Μορφή 1), φαρμακευτικά σκευάσματα που περιλαμβάνουν την ίδια, τη χρήση της στη θεραπεία και τις διαδικασίες για την παρασκευή της ίδιας.
CY20151100093T 2008-04-11 2015-01-29 Ανυδρη μορφη κρυσταλλικης μηλεϊνικης ορβεπιταντης (orvepitant maleate) CY1115961T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0806652.4A GB0806652D0 (en) 2008-04-11 2008-04-11 Anhydrous crystal form of orvepitant maleate
EP09731234.2A EP2297152B1 (en) 2008-04-11 2009-04-09 Anhydrous crystal form of orvepitant maleate

Publications (1)

Publication Number Publication Date
CY1115961T1 true CY1115961T1 (el) 2017-01-25

Family

ID=39433527

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20151100093T CY1115961T1 (el) 2008-04-11 2015-01-29 Ανυδρη μορφη κρυσταλλικης μηλεϊνικης ορβεπιταντης (orvepitant maleate)

Country Status (27)

Country Link
US (1) US8309553B2 (el)
EP (1) EP2297152B1 (el)
JP (2) JP5875863B2 (el)
KR (1) KR20110002090A (el)
CN (1) CN102066376B (el)
AR (1) AR071311A1 (el)
AU (1) AU2009235440B2 (el)
BR (1) BRPI0911678B8 (el)
CA (1) CA2721119C (el)
CL (1) CL2009000876A1 (el)
CY (1) CY1115961T1 (el)
DK (1) DK2297152T3 (el)
EA (1) EA017082B1 (el)
ES (1) ES2529295T3 (el)
GB (1) GB0806652D0 (el)
HR (1) HRP20141196T1 (el)
IL (1) IL208597A0 (el)
MX (1) MX2010011152A (el)
PE (1) PE20091839A1 (el)
PL (1) PL2297152T3 (el)
PT (1) PT2297152E (el)
RS (1) RS53732B1 (el)
SI (1) SI2297152T1 (el)
TW (1) TW201002714A (el)
UY (1) UY31758A (el)
WO (1) WO2009124996A1 (el)
ZA (1) ZA201007120B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8139718B2 (en) * 2007-10-30 2012-03-20 Elekta Ab (Publ) Radiotherapy apparatus
GB0806652D0 (en) * 2008-04-11 2008-05-14 Glaxo Group Ltd Anhydrous crystal form of orvepitant maleate
WO2014057003A1 (en) * 2012-10-11 2014-04-17 Nerre Therapeutics Limited Novel uses
RS59313B1 (sr) * 2016-01-08 2019-10-31 Nerre Therapeutics Ltd Orvepitant za lečenje hroničnog kašlja
IL312486B2 (en) 2017-04-10 2025-05-01 Chase Therapeutics Corp NK1 antagonist combination and method for treating synucleinopathies
KR20250069704A (ko) 2017-06-30 2025-05-19 체이스 테라퓨틱스 코포레이션 우울증을 치료하기 위한 nk-1 길항제 조성물 및 우울증 치료에 사용하는 방법
TWI785098B (zh) 2017-08-18 2022-12-01 開曼群島商科賽睿生命科學公司 Tg02之多晶型
AU2021246889A1 (en) * 2020-04-03 2022-10-13 Nerre Therapeutics Limited An NK-1 receptor antagonist for treating a disease selecting from sepsis, septic shock,, acute respiratory distress syndrome (ARDS) or multiple organ dysfunction syndrome (MODS)
MX2022014901A (es) 2020-06-02 2023-01-18 Nerre Therapeutics Ltd Antagonistas del receptor de neuroquinina (nk)-1 para su uso en el tratamiento de condiciones de fibrosis pulmonar promovidas por lesion mecanica a los pulmones.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203020D0 (en) * 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
AU2007253704A1 (en) 2006-05-22 2007-11-29 Vanda Pharmaceuticals, Inc. Treatment for depressive disorders
GB0621229D0 (en) * 2006-10-20 2006-12-06 Glaxo Group Ltd Novel use
US20100308579A1 (en) * 2007-11-02 2010-12-09 Entegris, Inc. Integral face seal
GB0806652D0 (en) * 2008-04-11 2008-05-14 Glaxo Group Ltd Anhydrous crystal form of orvepitant maleate

Also Published As

Publication number Publication date
EP2297152A1 (en) 2011-03-23
CA2721119C (en) 2016-04-05
EA017082B1 (ru) 2012-09-28
MX2010011152A (es) 2010-12-21
SI2297152T1 (sl) 2015-02-27
ZA201007120B (en) 2011-11-30
CA2721119A1 (en) 2009-10-15
US20110166150A1 (en) 2011-07-07
JP2011516532A (ja) 2011-05-26
EP2297152B1 (en) 2014-11-12
BRPI0911678B8 (pt) 2021-05-25
AU2009235440A1 (en) 2009-10-15
KR20110002090A (ko) 2011-01-06
PT2297152E (pt) 2015-02-16
CN102066376A (zh) 2011-05-18
PE20091839A1 (es) 2010-01-07
CN102066376B (zh) 2014-01-01
AR071311A1 (es) 2010-06-09
AU2009235440B2 (en) 2012-06-14
BRPI0911678B1 (pt) 2021-03-02
UY31758A (es) 2009-11-10
DK2297152T3 (da) 2015-01-26
HRP20141196T1 (hr) 2015-02-13
TW201002714A (en) 2010-01-16
JP5875863B2 (ja) 2016-03-02
RS53732B1 (sr) 2015-06-30
EA201071183A1 (ru) 2011-06-30
IL208597A0 (en) 2010-12-30
US8309553B2 (en) 2012-11-13
ES2529295T3 (es) 2015-02-18
CL2009000876A1 (es) 2010-05-14
PL2297152T3 (pl) 2015-04-30
JP2014205688A (ja) 2014-10-30
WO2009124996A1 (en) 2009-10-15
GB0806652D0 (en) 2008-05-14
BRPI0911678A2 (pt) 2015-10-13

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