AR057581A1 - Comprimido de disgregacion rapida intraoral - Google Patents
Comprimido de disgregacion rapida intraoralInfo
- Publication number
- AR057581A1 AR057581A1 ARP060104991A ARP060104991A AR057581A1 AR 057581 A1 AR057581 A1 AR 057581A1 AR P060104991 A ARP060104991 A AR P060104991A AR P060104991 A ARP060104991 A AR P060104991A AR 057581 A1 AR057581 A1 AR 057581A1
- Authority
- AR
- Argentina
- Prior art keywords
- disgregation
- intraoral rapid
- compressed
- intraoral
- disintegrant
- Prior art date
Links
- 239000007884 disintegrant Substances 0.000 abstract 2
- 239000008187 granular material Substances 0.000 abstract 2
- 239000007898 rapid-disintegration tablet Substances 0.000 abstract 2
- QNVKOSLOVOTXKF-UHFFFAOYSA-N 4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydron;chloride Chemical compound Cl.NC1=C(Br)C=C(Br)C=C1CNC1CCC(O)CC1 QNVKOSLOVOTXKF-UHFFFAOYSA-N 0.000 abstract 1
- 229960000985 ambroxol hydrochloride Drugs 0.000 abstract 1
- 230000006835 compression Effects 0.000 abstract 1
- 238000007906 compression Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 230000035807 sensation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente proporciona un comprimido de disgregacion rápida intraoral que se puede formar utilizando un aparato ordinario, que posee una dureza sin ningun problema práctico y que se desintegra rápidamente con una buena sensacion en la cavidad oral. El comprimido de disgregacion rápida intraoral producido mediante por compresion de un gránulo recubierto con un desintegrante, en donde el gránulo contiene también un desintegrante dentro del mismo e hidrocloruro de ambroxol como fármaco dentro y/o fuera del mismo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005328722 | 2005-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR057581A1 true AR057581A1 (es) | 2007-12-05 |
Family
ID=38023405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060104991A AR057581A1 (es) | 2005-11-14 | 2006-11-14 | Comprimido de disgregacion rapida intraoral |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10300021B2 (es) |
| EP (2) | EP1957051B1 (es) |
| JP (2) | JP4934144B2 (es) |
| KR (1) | KR101298379B1 (es) |
| CN (2) | CN103637996A (es) |
| AR (1) | AR057581A1 (es) |
| AU (1) | AU2006312566B2 (es) |
| CA (1) | CA2629487C (es) |
| ES (1) | ES2702757T3 (es) |
| PE (1) | PE20070698A1 (es) |
| TW (1) | TWI478732B (es) |
| WO (2) | WO2007055428A1 (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20070698A1 (es) * | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
| RU2478375C2 (ru) * | 2007-03-13 | 2013-04-10 | ДАЙНИППОН СУМИТОМО ФАРМА Ко., ЛТД. | Распадающаяся во рту таблетка |
| GB2453770A (en) | 2007-10-19 | 2009-04-22 | Reckitt Benckiser Healthcare | Oral composition comprising a cooling agent |
| JP5835875B2 (ja) * | 2009-06-29 | 2015-12-24 | 富士化学工業株式会社 | 口腔内速崩壊錠の製造方法 |
| UY33455A (es) * | 2010-06-16 | 2012-01-31 | Teijin Pharma Ltd | Tableta con núcleo recubierto de liberación controlada |
| KR101828630B1 (ko) * | 2010-07-09 | 2018-02-12 | 데이진 화-마 가부시키가이샤 | 구강 내 붕괴 정제 |
| NZ605562A (en) * | 2010-07-09 | 2013-11-29 | Teijin Pharma Ltd | Deuterated benzylbenzene derivatives and methods of use |
| CN103429223A (zh) * | 2011-01-17 | 2013-12-04 | 武田药品工业株式会社 | 口腔分散片 |
| WO2013001441A1 (en) * | 2011-06-29 | 2013-01-03 | Ranbaxy Laboratories Limited | Dry formulations of febuxostat |
| JP6823913B2 (ja) * | 2014-06-18 | 2021-02-03 | 大正製薬株式会社 | 固形製剤 |
| JP6073843B2 (ja) * | 2014-09-10 | 2017-02-01 | 佐藤製薬株式会社 | 硬度及び崩壊性に優れた口腔内崩壊錠の製造方法及び該製造方法により製造される口腔内崩壊錠 |
| EP3206671B1 (en) | 2014-10-16 | 2024-06-12 | Cargill, Incorporated | Process for preparing a directly compressible erythritol and uses thereof |
| WO2017217494A1 (ja) * | 2016-06-16 | 2017-12-21 | 東和薬品株式会社 | 口腔内崩壊錠 |
| WO2018021265A1 (ja) * | 2016-07-27 | 2018-02-01 | 沢井製薬株式会社 | 口腔内崩壊錠添加用組成物 |
| JP6201017B2 (ja) * | 2016-08-04 | 2017-09-20 | 佐藤製薬株式会社 | 硬度及び崩壊性に優れた口腔内崩壊錠の製造方法及び該製造方法により製造される口腔内崩壊錠 |
| JP6651638B2 (ja) * | 2016-09-06 | 2020-02-19 | 沢井製薬株式会社 | 口腔内崩壊錠添加用組成物 |
| WO2021099935A1 (en) * | 2019-11-18 | 2021-05-27 | Zycie Technolegal Llp | Pharmaceutical formulations for managing uric acid content in human body |
| JP7486258B2 (ja) * | 2019-12-26 | 2024-05-17 | 物産フードサイエンス株式会社 | 口腔内崩壊錠用顆粒、その製造方法および口腔内崩壊錠 |
| JP7195660B1 (ja) | 2021-09-09 | 2022-12-26 | 壽製薬株式会社 | 口腔内崩壊錠 |
| US20230420715A1 (en) | 2021-12-09 | 2023-12-28 | Bloom Energy Corporation | Fuel cell system and method of operating thereof at near one hundred percent fuel utilization |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US112196A (en) * | 1871-02-28 | Improvement in horse-collars | ||
| US215500A (en) * | 1879-05-20 | Improvement in distance-instruments | ||
| US134199A (en) * | 1872-12-24 | Improvement in car-couplings | ||
| US98227A (en) * | 1869-12-28 | Improved railway-car | ||
| US49315A (en) * | 1865-08-08 | Improvement in photographic cameras | ||
| US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
| DE69331839T2 (de) | 1992-01-29 | 2002-12-12 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| EP1380308B1 (en) * | 1996-07-12 | 2008-07-09 | Daiichi Pharmaceutical Co., Ltd. | Quickly disintegrable compression-molded materials and process for producing the same |
| AR016827A1 (es) | 1997-08-22 | 2001-08-01 | Smithkline Beecham Corp | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
| ID24475A (id) | 1997-11-18 | 2000-07-20 | Teijin Limeted Cs | Turunan-turunan amina siklik dan penggunaannya sebagai obat |
| PL340658A1 (en) | 1997-11-20 | 2001-02-12 | Teijin Ltd | Derivatives of biphenylamidine |
| ATE282962T1 (de) * | 1998-07-24 | 2004-12-15 | Haas Franz Waffel & Keksanlagen Industrie Gmbh | Verwendung von erythrit und/oder xylit in backmassen oder teigen für dauerbackwaren aus mehlen und/oder stärken als teilweiser oder vollständiger zuckerersatz |
| ATE481090T1 (de) | 1998-07-28 | 2010-10-15 | Takeda Pharmaceutical | Leicht zerfallende feste zubereitung |
| FR2795962B1 (fr) * | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
| JP4059671B2 (ja) | 2000-01-17 | 2008-03-12 | 帝人株式会社 | ベンズイミダゾール誘導体 |
| WO2002002083A1 (en) | 2000-06-30 | 2002-01-10 | Yamanouchi Pharmaceutical Co., Ltd. | Tablet rapidly disintegrating in mouth and process for producing the same |
| UA80393C2 (uk) * | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| JP4358117B2 (ja) | 2001-03-06 | 2009-11-04 | 協和発酵キリン株式会社 | 口腔内速崩壊錠 |
| US20040122106A1 (en) * | 2001-03-06 | 2004-06-24 | Motohiro Ohta | Tablets quickly disintegrating in oral cavity |
| FR2823668B1 (fr) * | 2001-04-20 | 2004-02-27 | Ethypharm Lab Prod Ethiques | Comprimes effervescents orodispersibles |
| WO2004064810A1 (ja) * | 2003-01-21 | 2004-08-05 | Nippon Shinyaku Co., Ltd. | 口腔内速崩性錠剤 |
| SI21403A (sl) | 2003-02-27 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Farmacevtska oblika z alendronsko kislino, njenimi solmi ali estri ter postopek za njeno pripravo |
| RU2375048C2 (ru) * | 2003-07-17 | 2009-12-10 | Д-Р Редди'С Лабораторис Инк. | Фармацевтическая композиция с набухающим покрытием |
| CA2540040C (en) | 2003-10-07 | 2012-09-11 | Andrx Pharmaceuticals Llc | Rapidly disintegrating formulation |
| JP4592272B2 (ja) | 2003-10-08 | 2010-12-01 | シャープ株式会社 | 給紙カセットおよび給紙装置 |
| US9884014B2 (en) * | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| JP5123517B2 (ja) | 2005-11-14 | 2013-01-23 | 帝人ファーマ株式会社 | アンブロキソール口腔内速崩性錠剤 |
| PE20070698A1 (es) | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
| WO2008122993A1 (en) | 2007-04-09 | 2008-10-16 | Panacea Biotec Limited | Controlled release formulation of coated microparticles |
-
2006
- 2006-11-13 PE PE2006001419A patent/PE20070698A1/es not_active Application Discontinuation
- 2006-11-14 EP EP06823462.4A patent/EP1957051B1/en not_active Not-in-force
- 2006-11-14 WO PCT/JP2006/323062 patent/WO2007055428A1/en not_active Ceased
- 2006-11-14 TW TW095142089A patent/TWI478732B/zh not_active IP Right Cessation
- 2006-11-14 CN CN201310682491.8A patent/CN103637996A/zh active Pending
- 2006-11-14 JP JP2008539669A patent/JP4934144B2/ja not_active Expired - Fee Related
- 2006-11-14 AU AU2006312566A patent/AU2006312566B2/en not_active Ceased
- 2006-11-14 CN CN200680042409.3A patent/CN101309672B/zh not_active Expired - Fee Related
- 2006-11-14 EP EP06823463A patent/EP1951203A4/en not_active Withdrawn
- 2006-11-14 ES ES06823462T patent/ES2702757T3/es active Active
- 2006-11-14 WO PCT/JP2006/323061 patent/WO2007055427A1/en not_active Ceased
- 2006-11-14 CA CA2629487A patent/CA2629487C/en not_active Expired - Fee Related
- 2006-11-14 AR ARP060104991A patent/AR057581A1/es unknown
- 2006-11-14 KR KR1020087014401A patent/KR101298379B1/ko not_active Expired - Fee Related
- 2006-11-14 US US12/092,852 patent/US10300021B2/en not_active Expired - Fee Related
-
2009
- 2009-09-18 US US12/562,674 patent/US9511029B2/en not_active Expired - Fee Related
-
2011
- 2011-08-10 JP JP2011175017A patent/JP2011225624A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN103637996A (zh) | 2014-03-19 |
| JP4934144B2 (ja) | 2012-05-16 |
| US20100009004A1 (en) | 2010-01-14 |
| CN101309672B (zh) | 2015-07-29 |
| CN101309672A (zh) | 2008-11-19 |
| JP2009515871A (ja) | 2009-04-16 |
| KR20080073335A (ko) | 2008-08-08 |
| WO2007055427A1 (en) | 2007-05-18 |
| KR101298379B1 (ko) | 2013-08-20 |
| JP2011225624A (ja) | 2011-11-10 |
| EP1957051A1 (en) | 2008-08-20 |
| PE20070698A1 (es) | 2007-08-17 |
| EP1957051A4 (en) | 2011-07-06 |
| AU2006312566A1 (en) | 2007-05-18 |
| WO2007055428A1 (en) | 2007-05-18 |
| CA2629487C (en) | 2014-11-18 |
| EP1951203A4 (en) | 2011-07-06 |
| TW200738282A (en) | 2007-10-16 |
| US9511029B2 (en) | 2016-12-06 |
| US10300021B2 (en) | 2019-05-28 |
| US20090117182A1 (en) | 2009-05-07 |
| ES2702757T3 (es) | 2019-03-05 |
| EP1957051B1 (en) | 2018-11-14 |
| EP1951203A1 (en) | 2008-08-06 |
| TWI478732B (zh) | 2015-04-01 |
| AU2006312566B2 (en) | 2012-04-12 |
| CA2629487A1 (en) | 2007-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |