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AR056720A1 - SUBSTTED TIAZOL COMPOSITE PHARMACEUTICALLY COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE A MEDICINAL PRODUCT - Google Patents

SUBSTTED TIAZOL COMPOSITE PHARMACEUTICALLY COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE A MEDICINAL PRODUCT

Info

Publication number
AR056720A1
AR056720A1 ARP060104641A ARP060104641A AR056720A1 AR 056720 A1 AR056720 A1 AR 056720A1 AR P060104641 A ARP060104641 A AR P060104641A AR P060104641 A ARP060104641 A AR P060104641A AR 056720 A1 AR056720 A1 AR 056720A1
Authority
AR
Argentina
Prior art keywords
prepare
substted
tiazol
composite
medicinal product
Prior art date
Application number
ARP060104641A
Other languages
Spanish (es)
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR056720A1 publication Critical patent/AR056720A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un compuesto de tiazol substituido de formula (1) en la que: R1 es etilo, propilo o isopropilo y R2 es hidrogeno, cloro, fluor o metilo; o una sal farmacéuticamente aceptable de los mismos. Los compuestos son agentes de apertura de canales de K activados por calcio de alta conductancia (canales Bkca), de interés en el campo de las afecciones urinarias. Composicion farmacéutica que lo comprende y su uso para preparar un medicamento util para tratar la vejiga hiperactiva (OAB).A substituted thiazole compound of formula (1) in which: R1 is ethyl, propyl or isopropyl and R2 is hydrogen, chlorine, fluorine or methyl; or a pharmaceutically acceptable salt thereof. The compounds are K channel opening agents activated by high conductance calcium (Bkca channels), of interest in the field of urinary disorders. Pharmaceutical composition that comprises it and its use to prepare a useful medication to treat overactive bladder (OAB).

ARP060104641A 2005-10-26 2006-10-24 SUBSTTED TIAZOL COMPOSITE PHARMACEUTICALLY COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE A MEDICINAL PRODUCT AR056720A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73029805P 2005-10-26 2005-10-26

Publications (1)

Publication Number Publication Date
AR056720A1 true AR056720A1 (en) 2007-10-17

Family

ID=37968661

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060104641A AR056720A1 (en) 2005-10-26 2006-10-24 SUBSTTED TIAZOL COMPOSITE PHARMACEUTICALLY COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE A MEDICINAL PRODUCT

Country Status (4)

Country Link
AR (1) AR056720A1 (en)
PE (1) PE20070530A1 (en)
TW (1) TW200732314A (en)
WO (1) WO2007051133A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5277256B2 (en) 2008-04-09 2013-08-28 田辺三菱製薬株式会社 Pyrimidine, pyridine and triazine derivatives as maxi-K channel openers
WO2022075780A1 (en) * 2020-10-07 2022-04-14 광주과학기술원 Pharmaceutical composition for preventing or treating overactive bladder

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4746741A (en) * 1986-06-19 1988-05-24 Eastman Kodak Company N,N'-bis[2-(3-methylphenyl)ethyl]-perylene-3,4:9,10-bis (dicarboximide) compound use thereof in multi-active photoconductive insulating elements exhibiting far red sensitivity
IE73235B1 (en) * 1991-03-25 1997-05-21 Akzo Nv 4-aryl-thiazole or imidazole derivatives
HU208429B (en) * 1991-05-03 1993-10-28 Gyogyszerkutato Intezet Process for producing 1-/3-chloro-phenyl/-4-methyl-7,8-dimethoxy-5h-2,3-benzodiazepine of high purity
US5668286A (en) * 1994-03-15 1997-09-16 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
NZ529043A (en) * 2001-04-16 2006-11-30 Tanabe Seiyaku Co Large conductance calcium-activated K channel opener
GB0121033D0 (en) * 2001-08-30 2001-10-24 Novartis Ag Organic compounds
US7057040B2 (en) * 2002-02-07 2006-06-06 Council Of Scientific And Industrial Research Substituted aryl alkenoic acid heterocyclic amides

Also Published As

Publication number Publication date
WO2007051133A3 (en) 2007-12-13
WO2007051133A2 (en) 2007-05-03
TW200732314A (en) 2007-09-01
PE20070530A1 (en) 2007-05-31

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Legal Events

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