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AR046078A1 - Nuevos sabores, modificadores de sabores, sustancias gustativas, mejoradores de gusto, sustancias gustativas y/o mejoradoras del gusto umani o dulce y uso de los mismos. - Google Patents

Nuevos sabores, modificadores de sabores, sustancias gustativas, mejoradores de gusto, sustancias gustativas y/o mejoradoras del gusto umani o dulce y uso de los mismos.

Info

Publication number
AR046078A1
AR046078A1 ARP040102813A ARP040102813A AR046078A1 AR 046078 A1 AR046078 A1 AR 046078A1 AR P040102813 A ARP040102813 A AR P040102813A AR P040102813 A ARP040102813 A AR P040102813A AR 046078 A1 AR046078 A1 AR 046078A1
Authority
AR
Argentina
Prior art keywords
taste
gustative
substances
flavors
modifiers
Prior art date
Application number
ARP040102813A
Other languages
English (en)
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of AR046078A1 publication Critical patent/AR046078A1/es

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52Adding ingredients
    • A23L2/56Flavouring or bittering agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20Synthetic spices, flavouring agents or condiments
    • A23L27/202Aliphatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20Synthetic spices, flavouring agents or condiments
    • A23L27/203Alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20Synthetic spices, flavouring agents or condiments
    • A23L27/205Heterocyclic compounds
    • A23L27/2054Heterocyclic compounds having nitrogen as the only hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/88Taste or flavour enhancing agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/65Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/54Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40Acylated substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
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    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3
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    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
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    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
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    • C07D263/56Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
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    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
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    • C07D285/135Nitrogen atoms
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    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
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    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
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Abstract

Se refiere a ciertas amidas de origen no natural, amidas no peptídicas y derivados de amidas, tales como oxalamidas, ureas y acrilamidas, son útiles modificadores de sabor o gusto, tales como saborizantes o agentes saborizantes y mejoradores de sabor o gusto, más en especial modificadores de gusto sabroso (el gusto "umami" del glutamato monosódico) o dulce, agentes saborizantes sabrosos o dulces o mejorados de sabor sabroso o dulce, para alimentos, bebidas y otros comestibles o productos o composiciones medicinales que se administran por vía oral.
ARP040102813A 2003-08-06 2004-08-06 Nuevos sabores, modificadores de sabores, sustancias gustativas, mejoradores de gusto, sustancias gustativas y/o mejoradoras del gusto umani o dulce y uso de los mismos. AR046078A1 (es)

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US55206404P 2004-03-09 2004-03-09

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AR046078A1 true AR046078A1 (es) 2005-11-23

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US (15) US20070104709A1 (es)
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AU (3) AU2004285410B2 (es)
BR (2) BRPI0413324A (es)
CA (3) CA2535036C (es)
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NZ (6) NZ545747A (es)
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RU (3) RU2419602C2 (es)
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Families Citing this family (256)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US20080244761A1 (en) * 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7309577B2 (en) 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US7763431B1 (en) 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
US7794959B2 (en) * 2001-04-05 2010-09-14 Senomyx, Inc. Identification of bitter receptors for hydrolyzed soy protein
US10078087B2 (en) * 2001-05-01 2018-09-18 Senomyx, Inc. Assays and enhancers of the human delta ENaC sodium channel
DK2327985T3 (en) * 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
US7794965B2 (en) 2002-03-13 2010-09-14 Signum Biosciences, Inc. Method of identifying modulators of PP2A methylase
MXPA06000266A (es) 2003-07-10 2006-03-30 Senomyx Inc Ensayos electrofisiologicos mejorados utilizando oocitos que expresan un enac humano y el uso de fenamilo para mejorar el efecto de intensificadores del enac en ensayos.
US7906627B2 (en) 2003-08-06 2011-03-15 Senomyx, Inc. Chimeric human sweet-umami and umami-sweet taste receptors
NZ545747A (en) 2003-08-06 2010-06-25 Senomyx Inc T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds
ES2342466T7 (es) 2003-11-21 2012-11-19 Givaudan Sa P-mentanocarboxamidas n-substituidas.
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
US7541055B2 (en) * 2004-09-10 2009-06-02 International Flavors & Fragrances Inc. Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions
US7427421B2 (en) * 2004-09-10 2008-09-23 International Flavors & Fragrances Inc. Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions
GB0425661D0 (en) * 2004-11-23 2004-12-22 Givaudan Sa Organic compounds
WO2006068745A1 (en) 2004-12-22 2006-06-29 Cargill, Incorporated Methods for determining cellular response to stimuli
US8221804B2 (en) * 2005-02-03 2012-07-17 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US20060257543A1 (en) * 2005-02-04 2006-11-16 Catherine Tachdjian Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
CA2597134C (en) 2005-02-04 2015-05-26 Senomyx, Inc. Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions
US20080319055A1 (en) * 2005-03-24 2008-12-25 Givaudan Sa Cooling Compounds
US7560465B2 (en) * 2005-03-31 2009-07-14 Richard Holschen Compositions and methods for delivery of caffeine
US7851006B2 (en) 2005-05-23 2010-12-14 Cadbury Adams Usa Llc Taste potentiator compositions and beverages containing same
US7851005B2 (en) 2005-05-23 2010-12-14 Cadbury Adams Usa Llc Taste potentiator compositions and beverages containing same
JP4750184B2 (ja) * 2005-05-23 2011-08-17 キャドバリー アダムス ユーエスエー エルエルシー 味覚増強組成物並びに味覚増強組成物を含有する、食用菓子製品及びチューインガム製品
TW200715993A (en) * 2005-06-15 2007-05-01 Senomyx Inc Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers
EP2368442B1 (en) 2005-07-27 2014-12-17 Symrise AG Use of hesperetin for enhancing the sweet taste
WO2007047988A2 (en) * 2005-10-20 2007-04-26 Senomyx, Inc. Chimeric human sweet-umami and umami-sweet taste receptors
KR101219281B1 (ko) * 2005-10-31 2013-01-08 (주)아모레퍼시픽 젠티식산 유도체 화합물과 그 제조방법 및 이를 함유하는미백화장료 조성물
WO2007052837A1 (en) * 2005-11-04 2007-05-10 Ajinomoto Co., Inc. Gastrointestinal function promoter
WO2007055393A1 (en) * 2005-11-09 2007-05-18 Ajinomoto Co., Inc. Kokumi-imparting agent
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
CA2629935C (en) * 2005-11-24 2016-01-19 Dompe S.P.A. (r)-arylalkylamino derivatives and pharmaceutical compositions containing them
US8007849B2 (en) * 2005-12-14 2011-08-30 International Flavors & Fragrances Inc. Unsaturated cyclic and acyclic carbamates exhibiting taste and flavor enhancement effect in flavor compositions
EP2008095A1 (en) 2006-04-20 2008-12-31 Givaudan SA Functional method to identify tastants
JP6095881B2 (ja) * 2006-04-20 2017-03-15 ジボダン エス エー 甘味増強に関する方法
CN101426381A (zh) * 2006-04-21 2009-05-06 西诺米克斯公司 含有高效鲜味调料的可食用组合物及其制备方法
EP2010009B1 (en) 2006-04-21 2017-06-14 Senomyx, Inc. Processes for preparing solid flavorant compositions
EP2035827B1 (en) * 2006-06-19 2012-10-17 Givaudan S.A. Nucleic acid, polypeptide and its use
US9244081B2 (en) * 2006-07-28 2016-01-26 Senomyx, Inc. Cell-based fluorescent assays for identifying alpha and delta ENaC modulators
RU2009101298A (ru) * 2006-08-22 2010-09-27 Рэдпойнт Био Корпорэйшн (Us) Гетероциклические соединения в качестве усилителей подслащивающего вещества
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
EP2121748B1 (en) * 2007-01-18 2018-03-21 Givaudan SA Chimeric umami taste receptor, nucleic acid encoding it and use thereof
EP1955601A1 (de) 2007-01-25 2008-08-13 Symrise GmbH & Co. KG Verwendung von Propenylphenylglycosiden zur Verstärkung süßer sensorischer Eindrücke
EP1977655B1 (de) 2007-03-29 2011-05-18 Symrise AG Aromakompositionen von Alkamiden mit Hesperetin und/oder 4-Hydroxydihydrochalkonen und deren Salzen zur Verstärkung süßer sensorischer Eindrücke
US8765207B2 (en) * 2007-04-10 2014-07-01 Paul Coles Fruit product containing sugar alcohol
DE502008000732D1 (de) * 2007-05-08 2010-07-15 Symrise Gmbh & Co Kg Substituierte Cyclopropancarbonsäure(3-methyl-cyclohexyl)amide als Geschmacksstoffe
EA200901546A1 (ru) 2007-05-17 2010-04-30 Кортекс Фармасеутикалс, Инк. Дизамещенные амиды для усиления глутаматергических синаптических ответов
US8709521B2 (en) * 2007-05-22 2014-04-29 The Coca-Cola Company Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
US7928111B2 (en) * 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US20080305500A1 (en) * 2007-06-08 2008-12-11 Senomyx, Inc. Novel cell-based assays for identifying enhancers or inhibitors of t1r taste receptors (t1r2/t1r3 sweet) and umami (t1r1/t1r3 umami) taste receptors
US8633186B2 (en) 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
AU2013202912B2 (en) * 2007-06-08 2016-10-27 Firmenich Incorporated Modulation of chemosensory receptors and ligands associated therewith
BRPI0813957A2 (pt) * 2007-06-29 2015-01-06 Sumitomo Chemical Co Agente de controle de doença de planta, e método de controle de doença de planta
EP2064959B1 (de) 2007-10-31 2012-07-25 Symrise AG Aromatische Neo-Menthylamide als Geschmacksstoffe
EP2245058A2 (en) * 2008-02-01 2010-11-03 Chromocell Corporation Cell lines expressing gaba receptor and methods using them
TWI429404B (zh) * 2008-03-03 2014-03-11 Senomyx Inc 異山梨醇衍生物及彼等作為風味改良劑、促味劑及促味增強劑之用途
EP2282735B1 (en) 2008-04-21 2019-01-16 Signum Biosciences, Inc. Pp2a modulators for treating alzheimer, parkinson, diabetes
EP2135516B1 (de) 2008-06-13 2012-08-15 Symrise AG Neo-Menthylderivate als Geschmacksstoffe
ES2647947T3 (es) 2008-07-31 2017-12-27 Senomyx, Inc. Procesos y productos intermedios para la preparación de potenciadores del sabor dulce
EP2328426B1 (en) 2008-07-31 2014-10-01 Senomyx, Inc. Compositions comrpising sweetness enhancers and methods of making them
DE102008042421A1 (de) 2008-09-26 2010-04-01 Symrise Gmbh & Co. Kg Geranylaminderivate der Oxalsäure
US8647887B2 (en) * 2009-01-29 2014-02-11 Commonwealth Scientific And Industrial Research Organisation Measuring G protein coupled receptor activation
PL216572B1 (pl) * 2009-02-02 2014-04-30 Inst Chemii Organicznej Polska Akademia Nauk Związki enaminokarbonylowe i ich zastosowanie
RU2377823C1 (ru) * 2009-02-13 2010-01-10 Олег Иванович Квасенков Способ производства ароматизированного тописолнечно-персикового напитка
RU2377829C1 (ru) * 2009-02-27 2010-01-10 Олег Иванович Квасенков Способ производства кофейного напитка "ступинский"
DE102009002268A1 (de) 2009-04-07 2010-10-14 Leibniz-Institut Für Pflanzenbiochemie 4,4'-Dihydroxydeoxybenzoine und deren Verwendung als Geschmacksverbesserer
EP2253226B1 (de) 2009-05-15 2015-07-15 Leibniz-Institut für Pflanzenbiochemie (IPB) Verwendung von Hydroxyflavan-Derivaten zur Geschmacksmodifizierung
CN102469816A (zh) * 2009-08-10 2012-05-23 斯托克里-丰康普公司 将类黄酮悬浮于饮料中的方法
EP2298084B1 (de) 2009-08-28 2011-10-19 Symrise AG Süßmittelreduzierte Produkte, Aromamischungen dafür sowie Verfahren zum Herstellen solcher Produkte
US10624372B2 (en) 2009-08-28 2020-04-21 Symrise Ag Reduced-sweetener products, flavoring mixtures for said reduced-sweetener products and process for the production of products of this type
US8293299B2 (en) 2009-09-11 2012-10-23 Kraft Foods Global Brands Llc Containers and methods for dispensing multiple doses of a concentrated liquid, and shelf stable Concentrated liquids
WO2011041686A1 (en) * 2009-10-01 2011-04-07 Mount Sinai School Of Medicine Of New York University Human type 1 taste receptor subunit 3 modulators and methods of using same
GB0917325D0 (en) 2009-10-02 2009-11-18 Givaudan Sa Flavour enhancement
DE102009046126A1 (de) 2009-10-28 2011-05-12 Symrise Ag Oral konsumierbare Zubereitung umfassend Wurzelextrakt aus Mondia whitei
JP2011116693A (ja) * 2009-12-02 2011-06-16 Univ Of Tokyo 甘味物質に対するヒト甘味受容体作用性甘味調節物質
JP5905187B2 (ja) * 2009-12-02 2016-04-20 国立大学法人 東京大学 甘味受容体発現コンストラクト、これを発現させた細胞体、及びその利用
MX2012006923A (es) * 2009-12-18 2012-07-10 Stokely Van Camp Inc Bebida de recuperacion con proteina.
PL2353403T3 (pl) 2010-02-01 2012-10-31 Symrise Ag Zastosowanie 1-(2,4-dihydroksy-fenylo)-3-(3-hydroksy-4-metoksy-fenylo)-propan-1-onu
GB201001796D0 (en) 2010-02-04 2010-03-24 Givaudan Sa Compounds
EP2552207B1 (en) * 2010-04-02 2019-08-21 Firmenich Incorporated Sweet flavor modifier
RU2597438C2 (ru) * 2010-04-15 2016-09-10 Крафт Фудс Груп Брэндс Ллс Соединения, композиции и способы для снижения или устранения горького вкуса
US9000054B2 (en) 2010-08-12 2015-04-07 Senomyx, Inc. Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
JP2014503473A (ja) * 2010-10-19 2014-02-13 エルセリクス セラピューティクス インコーポレイテッド 化学感覚受容体リガンドに基づく治療法
EP2629774A4 (en) * 2010-10-19 2014-08-27 Elcelyx Therapeutics Inc THERAPIES BASED ON CHEMOSOUS RECEPTOR LIGANDS
EP2629609A4 (en) * 2010-10-19 2014-08-27 Elcelyx Therapeutics Inc THERAPIES BASED ON CHEMOSOUS RECEPTOR LIGANDS
PE20140913A1 (es) * 2010-11-15 2014-08-22 Abbvie Inc Inhibidores de nampt y rock
WO2012072399A1 (en) * 2010-11-30 2012-06-07 Unilever Nv Refined plant isolates and process for the manufacture of a functional food ingredient from such plant isolate
GB201103103D0 (en) 2011-02-23 2011-04-06 Givaudan Sa Organic compounds
AU2012249720B2 (en) 2011-04-29 2015-03-26 Intercontinental Great Brands Llc Encapsulated acid, method for the preparation thereof, and chewing gum comprising same
EP2529632B1 (de) * 2011-05-31 2013-08-28 Symrise AG Zimtsäureamide als würzige Geschmacksstoffe
EP2529633B1 (de) 2011-06-01 2014-08-06 Symrise AG Oral konsumierbare Zubereitungen umfassend bestimmte süß schmeckende Triterpene und Triterpenglycoside
CN102311352B (zh) * 2011-07-11 2013-10-16 上海应用技术学院 一种2-甲氧基-4-甲基苄胺的合成方法
WO2013022948A1 (en) 2011-08-08 2013-02-14 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
SG10201606309WA (en) * 2011-08-12 2016-09-29 Senomyx Inc Sweet flavor modifier
EP2570036B1 (de) 2011-09-15 2014-06-18 Symrise AG Verwendung bestimmter Neoflavonoide zur Verstärkung und/oder Erzeugung eines süßen sensorischen Eindruckes
GB201118486D0 (en) 2011-10-26 2011-12-07 Givaudan Sa Organic compounds
GB201118480D0 (en) 2011-10-26 2011-12-07 Givaudan Sa Organic compounds
GB201118497D0 (en) 2011-10-26 2011-12-07 Givaudan Sa Organic compounds
GB201118481D0 (en) 2011-10-26 2011-12-07 Givaudan Sa Organic compounds
GB201118479D0 (en) 2011-10-26 2011-12-07 Givaudan Sa Organic compounds
WO2013135511A1 (en) 2012-03-12 2013-09-19 Imax Discovery Gmbh N-(2,4-dimethylpentan-3-yl)-methylbenzamides and their use as flavoring agents
WO2013143822A1 (en) 2012-03-26 2013-10-03 Imax Discovery Gmbh Adenosine as sweetness enhancer for certain sugars
WO2013158928A2 (en) 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
US11013248B2 (en) 2012-05-25 2021-05-25 Kraft Foods Group Brands Llc Shelf stable, concentrated, liquid flavorings and methods of preparing beverages with the concentrated liquid flavorings
RU2666534C2 (ru) 2012-08-06 2018-09-11 Сеномикс, Инк. Модификатор сладкого вкуса и аромата
EP2737807B1 (de) * 2012-11-30 2017-04-05 Symrise AG Verwendung von stickstoffhaltigen Derivaten der Zimtsäure als Geschmacksstoffe
EP2742983B1 (en) 2012-12-11 2017-08-23 Symrise AG Method for isolating fragrance and flavour compounds
US20160205979A1 (en) * 2012-12-21 2016-07-21 Firmenich Sa Taste-modifying combinations
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
US9169311B2 (en) 2013-03-15 2015-10-27 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
MX2015013013A (es) 2013-03-15 2015-12-01 Applied Food Biotech Inc Receptores felinos del gusto amargo y metodos.
EP3019034B1 (en) 2013-07-01 2018-10-31 Givaudan SA Organic compounds
EP2832233A1 (en) * 2013-07-30 2015-02-04 IMAX Discovery GmbH 1H-pyrrole-2,4-dicarbonyl-derivatives and their use as flavoring agents
EP2832234A1 (en) 2013-07-30 2015-02-04 IMAX Discovery GmbH Imidazo[1,2-a]pyridine-ylmethyl-derivatives and their use as flavoring agents
CA2941192A1 (en) 2013-09-11 2015-03-19 Bristol-Myers Squibb Company Aryl ether-base kinase inhibitors
SMT202100125T1 (it) 2013-11-18 2021-05-07 Forma Therapeutics Inc Composizioni di tetraidrochinolina come inibitori di bromodomini bet
US9422281B2 (en) 2013-11-18 2016-08-23 Forma Therapeutics, Inc. Benzopiperazine compositions as BET bromodomain inhibitors
JP2017502659A (ja) 2013-12-05 2017-01-26 ジボダン エス エー 有機化合物
EP2883459B1 (de) 2013-12-16 2018-04-04 Symrise AG Zubereitungen zur oralen Aufnahme
EP2918270A1 (de) 2014-03-12 2015-09-16 Symrise AG Aromatische Alkensäurederivate zur Appetithemmung und Stimmungsaufhellung
US10429560B2 (en) * 2014-03-26 2019-10-01 Lg Chem, Ltd. Methods for manufacturing polarizing element, polarizing element roll and single sheet type polarizing element having local bleaching areas
JP6755640B2 (ja) * 2014-03-28 2020-09-16 味の素株式会社 甘味受容体キメラタンパク質及びその利用
MX369091B (es) * 2014-05-09 2019-10-29 Firmenich & Cie Solubilizacion de modulador y sabor dulce.
AU2015343463A1 (en) 2014-11-07 2017-06-15 Senomyx, Inc. Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers
CN107249349B (zh) * 2014-12-10 2021-06-08 马斯公司 用于调节味觉受体的方法
CN107428638B (zh) 2015-01-23 2023-01-24 P2科学公司 包含新戊二醇二乙酸酯的芳香和香料组合物
MX389514B (es) 2015-10-01 2025-03-20 Firmenich Incorporated Compuestos útiles como moduladores de canal receptor 8 de potencial transitorio de melastatina (trpm8).
JP6949838B2 (ja) 2015-10-29 2021-10-13 フィルメニッヒ インコーポレイテッドFirmenich Incorporated 高甘味度甘味料
JP7026624B2 (ja) 2016-02-03 2022-02-28 フイルメニツヒ ソシエテ アノニム アミド化合物の溶液及び分散液
EP3623363A1 (en) 2016-09-21 2020-03-18 Celanese International Corporation Acesulfame potassium compositions and processes for producing same
CN108884064A (zh) 2016-09-21 2018-11-23 国际人造丝公司 乙酰舒泛钾组合物和其生产方法
EP3319949B1 (en) 2016-09-21 2020-07-22 Celanese International Corporation Acesulfame potassium compositions and processes for producing same
HRP20211400T1 (hr) 2016-09-21 2021-12-10 Celanese International Corporation Acesulfam kalij pripravci i postupci njihove proizvodnje
CN106620144B (zh) * 2016-12-29 2020-01-24 姜富春 一种治疗慢性盆腔炎的中药制剂及其制备方法
MY199685A (en) 2017-05-03 2023-11-17 Firmenich Incorporated Methods for making high intensity sweeteners
US20200277404A1 (en) * 2017-09-12 2020-09-03 Monell Chemical Senses Center Compositions and methods for regulation of immune cell activation and proliferation
ES2908668T3 (es) * 2017-09-13 2022-05-03 Syngenta Participations Ag Derivados de quinolina (tio)carboxamida microbiocidas
JP7173980B2 (ja) 2017-10-23 2022-11-17 日本たばこ産業株式会社 Gタンパク質共役受容体若しくはそのサブユニットを発現するためのコンストラクト及びその利用
EP3823455B1 (de) 2018-07-16 2025-10-01 Symrise AG Zusammensetzung zur substitution von zucker in backwaren
JP7453210B2 (ja) 2018-08-07 2024-03-19 フィルメニッヒ インコーポレイテッド 5-置換4-アミノ-1H-ベンゾ[c][1,2,6]チアジアジン2,2-ジオキシド並びにその配合物及び使用
CN119264123A (zh) 2018-08-10 2025-01-07 弗门尼舍公司 T2r54的拮抗剂以及它们的组合物及其用途
EP3850078A1 (en) 2018-09-10 2021-07-21 Heineken Supply Chain B.V. Low-alcohol beer with reduced wort flavor
US12286661B2 (en) 2018-11-07 2025-04-29 Firmenich Incorporated Methods for making high intensity sweeteners
CA3118675A1 (en) 2018-11-07 2020-05-14 Firmenich Incorporated Methods for making high intensity sweeteners
US20220071933A1 (en) 2019-01-18 2022-03-10 Symrise Ag Combination remedy
EP3704954A1 (en) 2019-03-05 2020-09-09 Symrise AG Mixture comprising d-allulose and taste modifying compounds
CN113271795A (zh) 2019-03-28 2021-08-17 弗门尼舍有限公司 调味料系统
WO2020200916A1 (en) 2019-04-04 2020-10-08 Firmenich Sa Mogroside compounds and uses thereof
EP3982756A1 (en) * 2019-06-12 2022-04-20 CORN Products Development Inc. Compositions with sugar like characteristics
JP2022537613A (ja) 2019-06-28 2022-08-29 フイルメニツヒ ソシエテ アノニム 脂肪ブレンド、そのエマルション、および関連する使用
BR112022001006A2 (pt) 2019-09-05 2022-04-12 Firmenich & Cie Derivados de flavanona e uso dos mesmos como intensificadores de dulçor
AU2020360594A1 (en) 2019-09-30 2022-04-07 Givaudan Sa Improvements in or relating to organic compounds
CN113226058A (zh) 2019-11-11 2021-08-06 弗门尼舍有限公司 姜酚化合物及其作为风味改良剂的用途
WO2021119035A1 (en) 2019-12-13 2021-06-17 Firmenich Incorporated Taste modifying compositions and uses thereof
US20230028760A1 (en) 2019-12-13 2023-01-26 Firmenich Incorporated Taste modifying compositions and uses thereof
US20230000122A1 (en) 2019-12-18 2023-01-05 Firmenich Incorporated Taste modifying compositions and uses thereof
US20230025283A1 (en) * 2019-12-18 2023-01-26 Firmenich Incorporated Taste Modifying Compositions and Uses Thereof
CN111170960B (zh) * 2020-01-17 2022-04-15 东莞波顿香料有限公司 肉香味化合物及其制备方法和香料添加剂
CN114127084B (zh) * 2020-03-05 2024-08-06 弗门尼舍有限公司 11-氧代-葫芦烷及其作为风味改良剂的用途
CN115279206A (zh) 2020-03-31 2022-11-01 弗门尼舍有限公司 风味剂组合物
EP4055006A1 (en) 2020-04-17 2022-09-14 Firmenich SA Amino acid derivatives and their use as flavor modifiers
BR112022016262A2 (pt) 2020-05-22 2022-10-25 Firmenich & Cie Composições para reduzir gosto salgado e uso das mesmas
US20240239771A1 (en) * 2020-05-29 2024-07-18 Taxis Pharmaceuticals, Inc. Bacterial efflux pump inhibitors
BR112022016411A2 (pt) 2020-06-03 2022-10-11 Firmenich & Cie Composições para reduzir gostos desagradáveis e usos das mesmas
MX2022015148A (es) 2020-06-24 2023-01-11 Firmenich & Cie Composiciones edulcorantes y usos de las mismas.
JP2023533893A (ja) 2020-07-14 2023-08-07 フイルメニツヒ ソシエテ アノニム オーラルケア製品における望ましくない味覚ノートの減少
EP4162273A1 (en) * 2020-07-24 2023-04-12 Firmenich Incorporated Savory taste enhancement via transmembrane region binding
EP4125428A1 (en) 2020-09-22 2023-02-08 Firmenich SA Wintergreen flavor compositions free of methyl salicylate
CN114343159A (zh) 2020-10-13 2022-04-15 弗门尼舍有限公司 丙二酰基甜菊醇糖苷及其可食用用途
EP4161292A1 (en) 2020-10-27 2023-04-12 Firmenich SA Conjugated diynes and their use as flavor modifiers
US20240036041A1 (en) * 2020-11-24 2024-02-01 Firmenich Incorporated Kokumi taste enhancement and related screening methods
JP2023552031A (ja) 2020-11-29 2023-12-14 フイルメニツヒ ソシエテ アノニム 過酸化物の異味を低減する組成物およびその使用
US20230397627A1 (en) 2020-12-23 2023-12-14 Firmenich Sa Uses of fat blends and emulsions thereof
WO2022138890A1 (ja) * 2020-12-25 2022-06-30 味の素株式会社 香料組成物
CN116828996A (zh) 2021-01-08 2023-09-29 西姆莱斯有限公司 用于酸味平衡的新型组合物
ES3018421T3 (es) 2021-01-13 2025-05-16 Firmenich Incorporated Composiciones que potencian el efecto refrescante
CN116963609A (zh) 2021-01-15 2023-10-27 弗门尼舍公司 包含罗汉果苷的甜味剂组合物及其用途
CN116997263A (zh) 2021-01-15 2023-11-03 弗门尼舍公司 包含赛门苷i的甜味剂组合物及其用途
CN117098460A (zh) 2021-01-15 2023-11-21 弗门尼舍公司 包含罗汉果苷的甜味剂组合物及其用途
WO2022171569A1 (en) 2021-02-10 2022-08-18 Firmenich Sa Fiber blends, sweetened fiber blends, and their comestible use
CN115315195B (zh) 2021-03-09 2024-07-02 弗门尼舍有限公司 羟基取代和甲氧基取代的类黄酮及其用途
EP4258899A1 (en) 2021-03-09 2023-10-18 Firmenich SA Hydroxy- and methoxy-substituted flavones and their use
WO2022214275A1 (en) 2021-04-06 2022-10-13 Firmenich Sa Use of gingerdiol compounds to enhance flavor
CN117279520A (zh) * 2021-04-26 2023-12-22 弗门尼舍公司 酰胺化合物及其作为风味修饰剂的用途
JP2024517692A (ja) 2021-04-26 2024-04-23 フィルメニッヒ インコーポレイテッド アミド化合物および風味修飾剤としてのその使用
BR112023022012A2 (pt) 2021-04-26 2023-12-26 Firmenich Incorporated Compostos de amida e seu uso como modificadores de sabor
WO2022238249A2 (en) 2021-05-11 2022-11-17 Firmenich Sa Process of making gingerol compounds and their use as flavor modifiers
WO2022248405A1 (en) 2021-05-24 2022-12-01 Firmenich Sa Flavored fiber blends and their comestible use
BR112023022601A2 (pt) 2021-05-28 2024-01-16 Firmenich Incorporated Composições que intensificam o efeito de refrescância
JP2024522442A (ja) 2021-06-02 2024-06-21 フイルメニツヒ ソシエテ アノニム 脱アセチル化の方法、組成物、およびその使用
US20250040582A1 (en) 2021-06-23 2025-02-06 Firmenich Sa Flavor-modifying compositions containing lactase
WO2023278394A1 (en) 2021-06-28 2023-01-05 Firmenich Incorporated Polycationic salts of phenolic compounds and uses thereof
EP4333645B1 (en) 2021-06-29 2025-03-05 Firmenich Incorporated Mogroside compounds and their comestible use
US20240237690A1 (en) 2021-06-29 2024-07-18 Firmenich Sa Licorice Compounds and Their Use as Flavor Modifiers
EP4384595A1 (en) 2021-09-27 2024-06-19 Firmenich Incorporated Use of vanillyl ethers to modify flavor of distilled spirits
WO2023046914A1 (en) 2021-09-27 2023-03-30 Firmenich Sa Flavor compositions containing iron compounds and their use
CN116058486A (zh) 2021-10-29 2023-05-05 味之素株式会社 麻辣味增强剂组合物和食品
AR127359A1 (es) 2021-11-01 2024-01-17 Firmenich & Cie Composición que comprende un nutriente y un modulador del sabor
CN118251134A (zh) * 2021-11-16 2024-06-25 弗门尼舍公司 酰胺化合物及其作为风味修饰剂的用途
US20250052739A1 (en) 2021-12-07 2025-02-13 Firmenich Incorporated Reduction of bitter taste of plant proteins and related assays and screening methods
US20250040583A1 (en) 2021-12-20 2025-02-06 Firmenich Sa Encapsulated metal compounds and comestible uses thereof
MX2024006776A (es) 2021-12-23 2024-06-20 Firmenich & Cie Composicion antimicrobiana que tiene colorante encapsulado.
CN114264766B (zh) * 2021-12-31 2022-08-16 江苏艾兰得营养品有限公司 一种vc软糖用甜橙香精评价方法
WO2023154597A1 (en) * 2022-02-11 2023-08-17 Firmenich Incorporated Cells expressing umami taste receptors and uses thereof
WO2023172415A1 (en) 2022-03-07 2023-09-14 Firmenich Incorporated Sweetener compositions
CN118973993A (zh) 2022-03-10 2024-11-15 弗门尼舍有限公司 甜味剂组合物
US20250176598A1 (en) * 2022-03-11 2025-06-05 Firmenich Incorporated Amide compounds and their use as flavor modifiers
JP2025509073A (ja) 2022-03-11 2025-04-11 フィルメニッヒ インコーポレイテッド フラバノン化合物およびそれらの風味改変剤としての使用
JP2025510215A (ja) 2022-03-25 2025-04-14 フイルメニツヒ ソシエテ アノニム 脂肪酸アミドおよびそれらの風味改変剤としての使用
EP4460184A1 (en) 2022-03-28 2024-11-13 Firmenich SA Non-animal protein compositions and uses thereof
CA3254517A1 (en) 2022-04-06 2023-10-12 Firmenich Incorporated TASTE MODIFICATION COMPOUNDS AND THEIR USES
WO2023198436A2 (en) 2022-04-11 2023-10-19 Firmenich Sa Sweetener compositions
EP4492989A1 (en) 2022-05-16 2025-01-22 Firmenich Incorporated Unsaturated fatty acids and their use to modify taste
JP2025517321A (ja) 2022-05-16 2025-06-05 フィルメニッヒ インコーポレイテッド 飽和脂肪酸および味を改変するための飽和脂肪酸の使用
CA3255347A1 (en) 2022-06-03 2023-12-07 Firmenich Sa FAT REDUCTION IN NON-ANIMAL PROTEIN COMPOSITIONS
EP4507521A1 (en) 2022-06-14 2025-02-19 Firmenich SA Polyelectrolyte complexes of proteins and uses thereof
WO2023247332A1 (en) 2022-06-24 2023-12-28 Firmenich Sa Taste modifying compositions and uses thereof
CN119604269A (zh) 2022-07-07 2025-03-11 弗门尼舍公司 增强清凉效果的组合物
WO2024041974A1 (en) 2022-08-22 2024-02-29 Firmenich Sa Gel compositions and their use in seafood analogue products
EP4547034A1 (en) 2022-10-26 2025-05-07 Firmenich SA Extrusion methods and flavored products formed thereby
EP4577059A1 (en) 2022-10-26 2025-07-02 Firmenich Incorporated Taste modifying compositions and uses thereof
CN120129464A (zh) 2022-10-27 2025-06-10 弗门尼舍有限公司 黄酮类化合物及其用途
EP4580420A1 (en) 2022-11-01 2025-07-09 Firmenich SA Low-calorie composition for flavor modification
CN120417784A (zh) 2022-12-22 2025-08-01 弗门尼舍有限公司 含烷基乳酸酯的天然甜味剂组合物及其用途
WO2024132554A1 (en) 2022-12-22 2024-06-27 Firmenich Sa Natural sweetener compositions and uses thereof
EP4601483A1 (en) 2022-12-23 2025-08-20 Firmenich Incorporated Beta-cyclodextrin and its use to modify flavor
CN120513026A (zh) 2023-01-09 2025-08-19 弗门尼舍有限公司 植物纤维用于改善发酵产品风味的用途
EP4665157A1 (en) 2023-02-15 2025-12-24 Firmenich SA Thermoresponsive gel composition and uses thereof
EP4630413A1 (en) 2023-02-25 2025-10-15 Firmenich Incorporated Flavanone compounds and their use as flavor modifiers
CN120916646A (zh) 2023-03-23 2025-11-07 弗门尼舍公司 香兰基醚修饰风味的用途
WO2024200171A1 (en) 2023-03-24 2024-10-03 Firmenich Sa Microparticles containing algal proteins and uses thereof
EP4661972A1 (en) 2023-03-28 2025-12-17 Firmenich SA Taste-modifying compositions and uses thereof
WO2024205979A1 (en) 2023-03-29 2024-10-03 Firmenich Incorporated Use of fatty acids to modify flavor
WO2024208837A1 (en) 2023-04-04 2024-10-10 Firmenich Sa Polysaccharide compositions and their comestible use
WO2024226609A2 (en) * 2023-04-24 2024-10-31 Baylor College Of Medicine Inhibitors of jun n-terminal kinases (jnk1, jnk2, and/or jnk3) and mitogen-activated protein kinases (mapk8, mapk9, and/or mapk10) and methods of using same
WO2024227789A1 (en) 2023-05-03 2024-11-07 Firmenich Sa Encapsulated phenolic compounds and their comestible use
GB202307621D0 (en) 2023-05-22 2023-07-05 Givaudan Sa Improvements in or relating to organic compounds
WO2024251755A1 (en) 2023-06-09 2024-12-12 Dsm-Firmenich Ag Compositions for reducing off notes and uses thereof
EP4480319A1 (en) 2023-06-22 2024-12-25 DSM-Firmenich AG Granola cluster
WO2025067974A1 (en) 2023-09-26 2025-04-03 Firmenich Sa Vegan cheese compositions and methods of making the same
WO2025073683A1 (en) 2023-10-04 2025-04-10 Firmenich Sa Flavanone compounds and their use as flavor modifiers
WO2025125286A1 (en) 2023-12-13 2025-06-19 Firmenich Sa Biopolymer compositions and their use in foamed compositions
WO2025132821A1 (en) 2023-12-19 2025-06-26 Firmenich Sa Comestible products having high fiber and low sugar
WO2025132803A1 (en) 2023-12-20 2025-06-26 Firmenich Sa 3-hydroxybenzoic acid and its use as a flavor modifier
WO2025191050A1 (en) 2024-03-15 2025-09-18 Firmenich Sa Lipid particles and their comestible use
WO2025202256A1 (en) 2024-03-28 2025-10-02 Firmenich Sa Cooling composition
WO2025221883A1 (en) 2024-04-17 2025-10-23 Firmenich Incorporated Taste modifying compositions and uses thereof
WO2025230968A1 (en) 2024-04-30 2025-11-06 Firmenich Incorporated Ketone compounds for enhancing alcohol perception

Family Cites Families (216)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US415052A (en) * 1889-11-12 And samuel j
US2987544A (en) 1961-06-06 Tranquilizers
BE418027A (es) 1935-10-22
GB502680A (en) 1936-10-10 1939-03-21 Du Pont Improvements in or relating to the isolation of boron fluoride
US2510945A (en) * 1945-04-24 1950-06-13 Us Agriculture Nu-cyclohexyl nicotinamide
US2519408A (en) * 1946-10-09 1950-08-22 Schering Corp Antispasmodics
NL186845B (nl) * 1953-04-16 Thomas Dwight Creekmore Orthodontische beugel.
GB858333A (en) * 1956-10-05 1961-01-11 Unilever Ltd Flavouring substances and their preparation
US3098693A (en) 1960-05-27 1963-07-23 Little Inc A Treatment of protein and peptide materials to form amide linkages
US3492323A (en) * 1963-08-21 1970-01-27 Hoffmann La Roche N-(2-propynyloxy)-sulfanilamides
US3281330A (en) 1964-03-20 1966-10-25 Upjohn Co Microbiological process for the oxygenation of cycloalkanes
US3294544A (en) * 1964-11-06 1966-12-27 Richardson Merrell Inc Artificial sweetener-arabinogalactan composition and edible foodstuff utilizing same
GB1193289A (en) * 1965-07-14 1970-05-28 Science Union & Cie New Isoindolino-Sulphonylurea Derivatives and Process for Preparing them
NL129208C (es) * 1965-07-14
NL131479C (es) * 1966-04-20
US3398155A (en) * 1966-05-31 1968-08-20 Abbott Lab 2, 6-dichloro-isonicotinamide derivatives and a method for their preparation
DE1695428C3 (de) * 1967-06-08 1978-10-05 Merck Patent Gmbh, 6100 Darmstadt Derivate des 5-Mercaptopyridoxins und Verfahren zu deren Herstellung
US4136163A (en) * 1971-02-04 1979-01-23 Wilkinson Sword Limited P-menthane carboxamides having a physiological cooling effect
US4150052A (en) * 1971-02-04 1979-04-17 Wilkinson Sword Limited N-substituted paramenthane carboxamides
US4021224A (en) * 1971-12-09 1977-05-03 Stauffer Chemical Company Herbicide compositions
US4034109A (en) * 1973-01-18 1977-07-05 Wilkinson Sword Limited Compounds having a physiological cooling effect and compositions containing them
US4177279A (en) * 1973-10-10 1979-12-04 John Wyeth & Brother Ltd. 1-[(3-Indolyl)-alkyl]-piperidyl ureas and hypotensive compositions
JPS5329211Y2 (es) 1973-10-15 1978-07-22
JPS5716973B2 (es) 1973-10-17 1982-04-08
GB1457671A (en) 1974-01-31 1976-12-08 Wilkinson Sword Ltd Flavour
GB1489359A (en) 1974-12-11 1977-10-19 Wilkinson Sword Ltd Alicyclic carboxamides having physiological cooling activity
US3944082A (en) 1974-12-20 1976-03-16 Harnischfeger Corporation Locking means for relatively movable boom sections of boom of mobile crane
JPS51106736A (ja) * 1975-03-14 1976-09-21 Rikagaku Kenkyusho Noengeiyosatsukinzai
US3988510A (en) * 1975-05-29 1976-10-26 International Flavors & Fragrances Inc. 3-Furyl sulfides and foodstuff flavor compositions comprising same
GB1502680A (en) 1975-06-03 1978-03-01 Wilkinson Sword Ltd Compositions for application to or consumption by the human body and containing compounds having a physiological cooling effect
JPS5825980B2 (ja) * 1976-02-12 1983-05-31 ヤマサ醤油株式会社 サイクリックヌクレオチドの定量法
US4049717A (en) * 1976-05-13 1977-09-20 American Cyanamid Company Novel 1,2,3,4-tetrahydro-4-oxo-(oxy)-1-naphthylamines and method of preparation thereof
US4332724A (en) * 1976-08-12 1982-06-01 American Cyanamid Co. Process for preparing 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophenes and 1,2,3,4-tetrahydro-4-oxonaphthalenes
EP0005501B1 (de) 1978-05-20 1981-11-25 Bayer Ag Heteroaryl-oxyessigsäureamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide
US4535084A (en) 1979-10-15 1985-08-13 Pfizer Inc. Certain 4-(2-hydroxyethylthiomethyl)pyridines and derivatives thereof having immunoregulatory activity
US4535081A (en) * 1979-11-23 1985-08-13 Pfizer Inc. Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor
US4391904A (en) * 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
DE3164618D1 (en) 1980-12-22 1984-08-09 Schering Ag 3-substituted 2,4,6-trihalogenobenzamides and their salts, their preparation and their use as substitutes for natural sweetening agents, and sweeteners containing them
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
FR2533210A1 (fr) * 1982-09-17 1984-03-23 Lyon I Universite Claude Edulcorants de synthese
GB8309855D0 (en) * 1983-04-12 1983-05-18 Tate & Lyle Plc Flavour modifiers
US4571345A (en) * 1983-06-13 1986-02-18 Cumberland Packing Corp. 1,1-Diaminoalkane derived sweeteners
US5476849A (en) * 1984-03-19 1995-12-19 The Rockefeller University Methods for glycosylation inhibition using amino-benzoic acids and derivatives
FR2573087B1 (fr) * 1984-11-09 1987-07-10 Inst Francais Du Petrole Procede d'adoucissement des coupes petrolieres effectue en absence de compose alcalin
IL76842A0 (en) 1984-12-28 1986-02-28 Monsanto Co Novel n-acyl-n-isopropyl-glycine derivatives
JPS61200951A (ja) * 1985-03-01 1986-09-05 Kyowa Hakko Kogyo Co Ltd シクロペンタンカルボン酸誘導体
US5506337A (en) * 1985-03-15 1996-04-09 Antivirals Inc. Morpholino-subunit combinatorial library and method
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
JPS61200951U (es) 1985-06-04 1986-12-16
JPS6181858A (ja) 1985-08-09 1986-04-25 Honda Motor Co Ltd 車両のアンチロック制動装置
CA1291031C (en) * 1985-12-23 1991-10-22 Nikolaas C.J. De Jaeger Method for the detection of specific binding agents and their correspondingbindable substances
US4835181A (en) * 1987-02-18 1989-05-30 Eli Lilly And Company Anticonvulsant agents using cyano dimethylphenyl benzamides
JPH0784428B2 (ja) * 1987-10-19 1995-09-13 鐘淵化学工業株式会社 ジペプチド誘導体およびそれを含有する甘味剤
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
US5176928A (en) * 1988-08-04 1993-01-05 The Nutrasweet Company Reduced calorie diary mix
JPH02108697A (ja) * 1988-10-15 1990-04-20 Kanegafuchi Chem Ind Co Ltd ジペプチド誘導体及びそれを含有するペプチド甘味剤
US4910031A (en) 1988-12-19 1990-03-20 Frito-Lay, Inc. Topped savory snack foods
JPH02108697U (es) 1989-02-17 1990-08-29
US5001115A (en) 1989-05-17 1991-03-19 University Of Florida Prodrugs of biologically active hydroxyaromatic compounds
DE3916430A1 (de) 1989-05-20 1990-11-22 Bayer Ag Verfahren zur herstellung von 3-amino-5-aminocarbonyl-1,2,4-triazol-derivaten
CA2020887A1 (en) 1989-07-28 1991-01-29 Michael Klaus Aromatic carboxylic amides
US5147463A (en) 1989-08-18 1992-09-15 Basf K&F Corporation Cyclic acetals
US5464764A (en) * 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5057601A (en) 1989-11-06 1991-10-15 Olin Corporation Process for producing a gel-free coagulated rubber with low ethylenic unsaturation
US5021249A (en) 1989-11-09 1991-06-04 Warner-Lambert Company Method of making a savory flavor granule and a free flowing savory flavor granule
US5272071A (en) * 1989-12-22 1993-12-21 Applied Research Systems Ars Holding N.V. Method for the modification of the expression characteristics of an endogenous gene of a given cell line
RU2128227C1 (ru) 1989-12-22 1999-03-27 Апплайд Резеч Системз АРС Холдинг Н.В. (NL) (Антильские острова) Способ активации транскрипционно-молчащего гена
JPH04505546A (ja) 1990-02-09 1992-09-24 アスラブ ソシエテ アノニム 写真平版マイクロ製造法を用いて製造した放射場静電マイクロモーター及び前記マイクロモーターの製造方法
JP2933975B2 (ja) 1990-04-26 1999-08-16 長谷川香料株式会社 飲食品の甘味強化方法
IE66205B1 (en) 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs
US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
US5393788A (en) 1990-07-10 1995-02-28 Smithkline Beecham Corporation Phenylalkyl oxamides
US5401629A (en) * 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
US5508407A (en) * 1991-07-10 1996-04-16 Eli Lilly And Company Retroviral protease inhibitors
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US6270989B1 (en) 1991-11-05 2001-08-07 Transkaryotic Therapies, Inc. Protein production and delivery
PT101031B (pt) 1991-11-05 2002-07-31 Transkaryotic Therapies Inc Processo para o fornecimento de proteinas por terapia genetica
FR2684670B1 (fr) * 1991-12-05 1995-04-07 Commissariat Energie Atomique Amides a substituant heterocyclique azote, leur procede de preparation et leur utilisation pour extraire selectivement les actinides (iii) et les separer en particulier des lanthanides (iii).
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5283722A (en) 1992-08-05 1994-02-01 Koenen Howard P Surgical-type glove and illuminator assembly
US5288514A (en) * 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US6664107B1 (en) * 1993-05-26 2003-12-16 Ontario Cancer Institute, University Health Network CD45 disrupted nucleic acid
US5426039A (en) * 1993-09-08 1995-06-20 Bio-Rad Laboratories, Inc. Direct molecular cloning of primer extended DNA containing an alkane diol
US5547966A (en) 1993-10-07 1996-08-20 Bristol-Myers Squibb Company Aryl urea and related compounds
NZ270267A (en) * 1993-12-30 1997-03-24 Hoechst Ag 3-hydroxypyridin-2yl (and -quinolin-2-yl) carboxamide derivatives and pharmaceutical compositions
ATE346598T1 (de) 1994-01-10 2006-12-15 Teva Pharma 1-aminoindanderivate und zusammensetzungen hiervon
US5877218A (en) * 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
US5519134A (en) * 1994-01-11 1996-05-21 Isis Pharmaceuticals, Inc. Pyrrolidine-containing monomers and oligomers
US5593853A (en) * 1994-02-09 1997-01-14 Martek Corporation Generation and screening of synthetic drug libraries
US5691188A (en) * 1994-02-14 1997-11-25 American Cyanamid Company Transformed yeast cells expressing heterologous G-protein coupled receptor
US5539083A (en) * 1994-02-23 1996-07-23 Isis Pharmaceuticals, Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis
US5522175A (en) 1994-06-01 1996-06-04 Biosource Technologies, Inc. Natural savory and umami flavoring materials from dehydrated mushroom
US5525735A (en) * 1994-06-22 1996-06-11 Affymax Technologies Nv Methods for synthesizing diverse collections of pyrrolidine compounds
US5549974A (en) * 1994-06-23 1996-08-27 Affymax Technologies Nv Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
JPH08103243A (ja) * 1994-10-06 1996-04-23 T Hasegawa Co Ltd 持続性香気香味賦与剤
CA2177380A1 (fr) * 1994-10-07 1996-04-18 Godefridus Van Den Ouweland Compositions aromatisantes et procede d'aromatisation
US5801195A (en) 1994-12-30 1998-09-01 Celgene Corporation Immunotherapeutic aryl amides
ZA96211B (en) 1995-01-12 1996-07-26 Teva Pharma Compositions containing and methods of using 1- aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
GB2334822B (en) 1995-04-10 1999-10-20 Otter Controls Ltd Thermal control for liquid heating vessels
DE69607974T2 (de) 1995-05-31 2000-10-05 Ihara Chemical Industry Co., Ltd. Phenylalkanamid-derivate und land- und gartenbauwirtschaftliche baterizide
JPH10510433A (ja) 1995-06-06 1998-10-13 アイシス・ファーマシューティカルス・インコーポレーテッド 高いキラル純度のホスホロチオエート結合を有するオリゴヌクレオチド
US5977322A (en) 1995-06-14 1999-11-02 The Regents Of The University Of California High affinity human antibodies to tumor antigens
US5985662A (en) 1995-07-13 1999-11-16 Isis Pharmaceuticals Inc. Antisense inhibition of hepatitis B virus replication
JPH10507086A (ja) * 1995-07-26 1998-07-14 フイルメニツヒ ソシエテ アノニム フレーバー付けられた製品及びその製法
AU6777896A (en) * 1995-08-25 1997-03-19 E.I. Du Pont De Nemours And Company Bicyclic herbicides
US6133317A (en) 1995-11-15 2000-10-17 Hart; Francis J. Oxalic acid or oxalate composition and method of treatment
AU1618697A (en) 1996-02-06 1997-08-28 Japan Tobacco Inc. Novel compounds and pharmaceutical use thereof
AU5926698A (en) * 1997-01-22 1998-08-07 Eli Lilly And Company Process for preparing indane-like compounds
EP0964849B1 (en) 1997-01-29 2003-06-04 Pfizer Inc. Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
US6462148B1 (en) * 1997-04-07 2002-10-08 Hitachi Chemical Co., Ltd. Adhesive film of quinoline polymer and bismaleimide
AR013079A1 (es) 1997-05-06 2000-12-13 Smithkline Beecham Corp Derivados sustituidos de tetrahidrofurano-3-onas, de tetrahidropirano-3- onas y tetrahidrotiofen-3-onas, un procedimiento para su preparacion unacomposicion farmaceutica de un medicamento util como inhibidores de proteasas e intermediarios
US5945441A (en) 1997-06-04 1999-08-31 Gpi Nil Holdings, Inc. Pyrrolidine carboxylate hair revitalizing agents
MY119059A (en) 1997-08-11 2005-03-31 Cadbury Adams Usa Llc Enhanced flavoring compositions containing n-ethyl-p-menthane-3-carboxamide and method of making and using same
EP1034783B1 (en) * 1997-10-27 2004-12-15 Sumitomo Pharmaceuticals Company, Limited Amide derivatives for the treatment of retinal neurodegenerative disorders
US6429207B1 (en) * 1997-11-21 2002-08-06 Nps Pharmaceuticals, Inc. Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases
CN1158264C (zh) 1997-11-21 2004-07-21 Nps药物有限公司 用于治疗中枢神经系统疾病的代谢性谷氨酸受体拮抗剂
US6432454B1 (en) 1997-12-12 2002-08-13 C. V. Technologies, Inc. Processes of making north american ginseng fractions, products containing them, and use as immunomodulators
ATE238694T1 (de) 1998-01-05 2003-05-15 Arla Foods Amba Verwendung von t-tagatose als synergist und geschmacksverstaerker
DE19808261A1 (de) * 1998-02-27 1999-10-28 Bayer Ag Arylphenylsubstituierte cyclische Ketoenole
DE19818732A1 (de) * 1998-04-27 1999-10-28 Bayer Ag Arylphenylsubstituierte cyclische Ketoenole
EP1077699A1 (en) * 1998-05-19 2001-02-28 Centaur Pharmaceuticals, Inc. Amide therapeutics for the treatment of inflammatory bowel disease
US7402400B2 (en) * 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
JP2002521049A (ja) 1998-07-28 2002-07-16 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 感覚伝達に関与するgタンパク質共役型レセプターをコードする核酸
US7588900B2 (en) * 2001-07-03 2009-09-15 The Regents Of The University Of California Mammalian sweet and amino acid heterodimeric taste receptors
CN1178952C (zh) * 1998-07-28 2004-12-08 加利福尼亚大学董事会 编码与感觉转导有关的g-蛋白偶联受体的核酸
PE20000942A1 (es) 1998-07-31 2000-09-28 Lilly Co Eli Derivados de amida, carbamato y urea
US6617351B1 (en) * 1998-07-31 2003-09-09 Eli Lilly And Company Amide, carbamate, and urea derivatives
JP2000169438A (ja) 1998-10-02 2000-06-20 Kumiai Chem Ind Co Ltd アリ―ル酢酸アミド誘導体及び農園芸用殺菌剤
US6399731B2 (en) 1998-10-08 2002-06-04 The University Of Akron Chain transfer agents and its use in polymer synthesis
CA2353627C (en) * 1998-11-04 2010-10-26 Keiichi Imamura Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
AUPP891299A0 (en) 1999-02-26 1999-03-25 Fujisawa Pharmaceutical Co., Ltd. New 6-membered cyclic compounds
US6362165B1 (en) * 1999-03-30 2002-03-26 Pharmacor Inc. Hydroxyphenyl derivatives with HIV integrase inhibitory properties
JP2000344752A (ja) * 1999-04-01 2000-12-12 Sumitomo Pharmaceut Co Ltd 点眼剤
TW593241B (en) 1999-04-20 2004-06-21 Hoffmann La Roche Carbamic acid derivatives
AU5127800A (en) * 1999-05-13 2000-12-05 Nutrasweet Company, The Use of additives to modify the taste characteristics of n-neohexyl-alpha-aspartyl-l-phenylalanine methyl ester
TR200200587T2 (tr) * 1999-07-20 2004-12-21 Dow Agrosciences Llc Mantar öldürücü heterosiklik aromatik amitler ve bileşimleri, bunları kullanma ve hazırlama yöntemleri
US6463445B1 (en) 1999-08-27 2002-10-08 Sony Electronics Inc. Multimedia information retrieval system and method including format conversion system and method
WO2001035768A1 (en) 1999-11-15 2001-05-25 J.Manheimer, Inc. Flavor freshness enhancers
AU2001228811A1 (en) * 2000-01-26 2001-08-07 Ono Pharmaceutical Co. Ltd. Nitrogen-containing 5-membered cyclic compounds and drugs containing these compounds as the active ingredient
JP3587361B2 (ja) 2000-01-27 2004-11-10 キヤノン株式会社 有機発光素子
JP3112457B2 (ja) 2000-03-01 2000-11-27 曽田香料株式会社 甘味強化剤
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
US6608176B2 (en) 2000-03-31 2003-08-19 University Of Miami Taste receptor for umami (monosodium glutamate) taste
EP1692952A3 (en) 2000-04-06 2006-10-25 Quest International B.V. Flavouring a foodstuff with compounds containing a sulphur atom linked to two specific atoms or groups
WO2001077676A1 (en) * 2000-04-07 2001-10-18 Senomyx, Inc. T2r taste receptors and genes encoding same
AU2001251259A1 (en) 2000-04-07 2001-10-23 Senomyx, Inc. Novel signal transduction molecules
DE10019145A1 (de) 2000-04-18 2001-10-25 Bayer Ag Phenylsubstituierte 4-Hydroxy-tetrahydropyridone
DE10021246A1 (de) 2000-04-25 2001-10-31 Schering Ag Substituierte Benzoesäureamide und deren Verwendung als Arzneimittel
JP3886897B2 (ja) 2000-06-21 2007-02-28 エフ.ホフマン−ラ ロシュ アーゲー ベンゾチアゾール誘導体
US7374878B2 (en) * 2000-06-22 2008-05-20 Senomyx, Inc. Receptor fingerprinting, sensory perception, and biosensors of chemical sensants
DE10030891A1 (de) * 2000-06-23 2002-01-03 Haarmann & Reimer Gmbh 3,4-Dihydroxybenzyl-substituierte Kohlensäurederivate und ihre Verwendung als Antioxidantien in kosmetischen und pharmazeutischen Präparaten
US6399641B1 (en) 2000-07-13 2002-06-04 Hoffmann-La Roche Inc. 2H-tetrazole-amide compounds with therapeutic activity as metabotropic glutamate receptor agonists
US7041457B2 (en) * 2000-10-30 2006-05-09 Senomyx, Inc. Gαq protein variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
AU2002213409A1 (en) * 2000-10-30 2002-05-15 Senomyx, Inc. Galphaqproetin variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
US6365215B1 (en) 2000-11-09 2002-04-02 International Flavors & Fragrances Inc. Oral sensory perception-affecting compositions containing dimethyl sulfoxide, complexes thereof and salts thereof
JP3744791B2 (ja) 2000-12-01 2006-02-15 株式会社リコー トナーリサイクル装置およびそれを備える電子写真式画像形成装置
TW201022287A (en) * 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
JP2002234898A (ja) * 2001-02-08 2002-08-23 Ajinomoto Co Inc 新規n−アルキルアスパルチルジペプチド誘導体及び甘味剤
US20040063742A1 (en) 2001-02-15 2004-04-01 Dan Peters Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity
DE10109856A1 (de) * 2001-03-01 2002-09-05 Bayer Ag Arzneimittel gegen virale Erkrankungen
US6617249B2 (en) 2001-03-05 2003-09-09 Agilent Technologies, Inc. Method for making thin film bulk acoustic resonators (FBARS) with different frequencies on a single substrate and apparatus embodying the method
US7309577B2 (en) * 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US7301009B2 (en) * 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7368285B2 (en) * 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US6955887B2 (en) * 2001-03-30 2005-10-18 Senomyx, Inc. Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling
US7338771B2 (en) * 2001-07-10 2008-03-04 Alexey Pronin Use of specific T2R taste receptors to identify compounds that block bitter taste
DE10117823A1 (de) 2001-04-10 2002-10-17 Merck Patent Gmbh Oxalsäurederivate
EP1252825A1 (en) 2001-04-25 2002-10-30 Société des Produits Nestlé S.A. Flavouring compositions
US20030089885A1 (en) * 2001-04-25 2003-05-15 Senomyx, Inc. Use of low molecular weight acetal, alcohol, acylated alcohol and ester compounds to block or reduce odor of carboxylic acids
EP1389426A4 (en) * 2001-04-25 2005-01-12 Yakult Honsha Kk FERMENTED FOODS AND METHOD FOR THEIR PRODUCTION
US20040072254A1 (en) * 2001-05-01 2004-04-15 Senomyx, Inc. High throughput cell-based assay for monitoring sodium channel activity and discovery of salty taste modulating compounds
CN100489102C (zh) 2001-06-26 2009-05-20 塞诺米克斯公司 T1r异源寡聚的味觉受体和表达所述受体的细胞系及其在鉴定味觉化合物中的用途
DK2327985T3 (en) * 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
CA2452315A1 (en) * 2001-07-06 2003-01-16 Senomyx, Inc. Expression of functional human olfactory cyclic nucleotide gated (cng) channel in recombinant host cells and use thereof in cell based assays to identify smell modulators
EA006769B1 (ru) 2001-08-06 2006-04-28 Фармация Италия С.П.А. Производные аминоизоксазола в качестве ингибиторов киназы
EP1291342A1 (en) * 2001-09-06 2003-03-12 Societe Des Produits Nestle S.A. Pyridinium-betain compounds as taste enhancer
EP1436249B1 (en) * 2001-09-21 2013-11-06 Eli Lilly And Company Muscarinic agonists
JP4840837B2 (ja) * 2001-09-28 2011-12-21 日本たばこ産業株式会社 旨味を有する新規ペプチド、及びそれを旨味成分とする調味料
WO2003030937A1 (en) * 2001-10-05 2003-04-17 Ono Pharmaceutical Co., Ltd. Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists
JP2005507932A (ja) 2001-10-12 2005-03-24 バイエル・フアーマシユーチカルズ・コーポレーシヨン 肥満の処置のためのフェニル置換5−員窒素含有複素環
GB0124941D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
CN1205175C (zh) * 2001-11-02 2005-06-08 中国人民解放军军事医学科学院毒物药物研究所 胺衍生物在制备具有抗肺动脉高压作用的药物中用途
US7329426B2 (en) 2001-11-13 2008-02-12 Applied Food Biotechnology, Inc. Treatment of vegetable oils or animal fats with sulfur or nitrogen donor compounds for animal food flavorings
EP1312268A1 (en) * 2001-11-19 2003-05-21 Société des Produits Nestlé S.A. Flavouring compositions
US7208290B2 (en) * 2001-12-14 2007-04-24 Senomyx, Inc. Methods of co-expressing umami taste receptors and chimeric Gα15 variants
US7344845B2 (en) * 2001-12-21 2008-03-18 Senomyx, Inc. Olfactory receptor for isovaleric acid and related malodorants and use thereof in assays for identification of blockers of malodor
ATE320196T1 (de) * 2001-12-27 2006-04-15 Symrise Gmbh & Co Kg Verwendung von ferulasäureamiden als aromastoffe
US7057040B2 (en) 2002-02-07 2006-06-06 Council Of Scientific And Industrial Research Substituted aryl alkenoic acid heterocyclic amides
US6818772B2 (en) * 2002-02-22 2004-11-16 Abbott Laboratories Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
EP1500650A4 (en) 2002-04-26 2006-08-23 Ishihara Sangyo Kaisha PYRIDINE COMPOUNDS OR SALTS THEREOF AND HERBICIDES CONTAINING SAME
CN1658849A (zh) * 2002-06-05 2005-08-24 株式会社医药分子设计研究所 Ap-1和nfat活化抑制剂
US20040006135A1 (en) 2002-06-19 2004-01-08 Pfizer Inc. Combination treatment for depression and anxiety
JP2006515157A (ja) 2002-07-29 2006-05-25 セノミックス、インコーポレイテッド 新規な苦味受容体t2r76の同定
GB0221697D0 (en) 2002-09-18 2002-10-30 Unilever Plc Novel compouds and their uses
US7635709B2 (en) * 2002-09-26 2009-12-22 The United States Of America As Represented By The Department Of Veterans Affairs Compositions and methods for bowel care in individuals with chronic intestinal pseudo-obstruction
ATE368678T1 (de) 2003-03-10 2007-08-15 Nestec Sa Pyridinium-betain verbindungen und deren verwendung
KR101146806B1 (ko) 2003-03-12 2012-05-22 메이브릿지 리미티드 프탈라지논 유도체
US20060292097A1 (en) 2003-04-08 2006-12-28 Luca Turin Fragrance compositions comprising benzo[4,5]thieno{3,2-b]pyran-2-one
DE602004027171D1 (de) 2003-04-11 2010-06-24 High Point Pharmaceuticals Llc Verbindungen mit Aktivität an der 11Beta-Hydroxasteroiddehydrogenase
US20060094699A1 (en) * 2003-04-11 2006-05-04 Kampen Gita Camilla T Combination therapy using an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and a glucocorticoid receptor agonist to minimize the side effects associated with glucocorticoid receptor agonist therapy
PL1638941T3 (pl) 2003-05-22 2010-11-30 Abbvie Bahamas Ltd Indazolowe, benzizoksazolowe i benzizotiazolowe inhibitory kinaz
NZ545747A (en) 2003-08-06 2010-06-25 Senomyx Inc T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds
US20060045953A1 (en) 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
US7191089B2 (en) 2004-12-01 2007-03-13 Freescale Semiconductor, Inc. System and method for fall detection
WO2006084245A2 (en) 2005-02-03 2006-08-10 Educational Testing Service Method and system for detecting off-topic essays without topic-specific training
CA2597134C (en) * 2005-02-04 2015-05-26 Senomyx, Inc. Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions
US20060257543A1 (en) * 2005-02-04 2006-11-16 Catherine Tachdjian Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
TW200715993A (en) * 2005-06-15 2007-05-01 Senomyx Inc Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers
EP2010009B1 (en) 2006-04-21 2017-06-14 Senomyx, Inc. Processes for preparing solid flavorant compositions

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