AR022725A1 - Hidrolisis enzimatica enantioselectiva de esteres 3-sustituidos de acido glutarico - Google Patents
Hidrolisis enzimatica enantioselectiva de esteres 3-sustituidos de acido glutaricoInfo
- Publication number
- AR022725A1 AR022725A1 ARP000100766A AR022725A1 AR 022725 A1 AR022725 A1 AR 022725A1 AR P000100766 A ARP000100766 A AR P000100766A AR 022725 A1 AR022725 A1 AR 022725A1
- Authority
- AR
- Argentina
- Prior art keywords
- enantioselectiva
- esteres
- substitutes
- glutaric acid
- enzymatic hydrolysis
- Prior art date
Links
- RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical compound CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 title 1
- JFCQEDHGNNZCLN-UHFFFAOYSA-N anhydrous glutaric acid Natural products OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 title 1
- 230000007071 enzymatic hydrolysis Effects 0.000 title 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Se presenta un proceso un proceso para preparar un compuesto de enantiomero S de la formula (1) en exceso enantiomérico, o un compuesto del enantiomero Rcon la formula (2) en exceso enantiomérico, proceso que comprende hidrolizar un compuesto que tiene la formula (3) con: (a) una enzima apta para producir unexceso enantiomérico del compuesto del enantiomero S de la formula (1) de por lo menos 70% o (b) una enzima con capacidad para producir un excesoenantiomérico del compuesto del enantiomero Rde la formula (2) de por lo menos 70%, donde R1 es seleccionado entre el grupo que consiste en alquilo, arilo,aralquilo, cicloalquilo o cicloalquilalquilo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25947299A | 1999-02-26 | 1999-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR022725A1 true AR022725A1 (es) | 2002-09-04 |
Family
ID=22985103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000100766 AR022725A1 (es) | 1999-02-26 | 2000-02-23 | Hidrolisis enzimatica enantioselectiva de esteres 3-sustituidos de acido glutarico |
Country Status (3)
| Country | Link |
|---|---|
| AR (1) | AR022725A1 (es) |
| AU (1) | AU3500500A (es) |
| WO (1) | WO2000050628A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006271356A1 (en) * | 2005-07-18 | 2007-01-25 | Pfizer Limited | Process for the preparation of sulfonamide derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3224019C1 (de) * | 1982-06-28 | 1984-02-16 | Takara Shuzo Co., Ltd., Kyoto | Verfahren zur Herstellung von ß-(S)-Aminoglutarsäuremonoalkylestern |
| WO1993004058A1 (en) * | 1991-08-22 | 1993-03-04 | Chiroscience Limited | Chiral glutarate esters, their resolution and derived glutarimide compounds |
| DE19623142A1 (de) * | 1996-06-10 | 1997-12-11 | Huels Chemische Werke Ag | Enantiomerenangereicherte, durch einen tertiären Kohlenwasserstoffrest substituierte Malonsäuremonoester sowie deren Herstellung |
-
2000
- 2000-02-23 AR ARP000100766 patent/AR022725A1/es unknown
- 2000-02-24 WO PCT/US2000/004668 patent/WO2000050628A1/en not_active Ceased
- 2000-02-24 AU AU35005/00A patent/AU3500500A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000050628A1 (en) | 2000-08-31 |
| AU3500500A (en) | 2000-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |