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AR018260A1 - A PROCESS TO PREPARE A GAMMAGLOBULIN SOLUTION THAT CAN BE ADMINISTERED INTRAVENOUSLY, AND GAMMAGLOBULIN SOLUTION OBTAINED BY DICHOPROCESS - Google Patents

A PROCESS TO PREPARE A GAMMAGLOBULIN SOLUTION THAT CAN BE ADMINISTERED INTRAVENOUSLY, AND GAMMAGLOBULIN SOLUTION OBTAINED BY DICHOPROCESS

Info

Publication number
AR018260A1
AR018260A1 ARP980106616A ARP980106616A AR018260A1 AR 018260 A1 AR018260 A1 AR 018260A1 AR P980106616 A ARP980106616 A AR P980106616A AR P980106616 A ARP980106616 A AR P980106616A AR 018260 A1 AR018260 A1 AR 018260A1
Authority
AR
Argentina
Prior art keywords
gammaglobulin
administered intravenously
dichoprocess
prepare
gammaglobulin solution
Prior art date
Application number
ARP980106616A
Other languages
Spanish (es)
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Publication of AR018260A1 publication Critical patent/AR018260A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un proceso para producir una solucion de gammaglobulina que puede ser administrada por vía intravenosa, sustancialmente libre de virus contaminantes,mediante el tratamiento con calor para inactivacion viral y fraccionamiento de una solucion de gammaglobulina impura y luego tratando la gammagloblulinapurificada con un solvente-detergente para inactivacion viral adicional. Solucion de gammaglobulina obtenida por dicho proceso.A process for producing a gamma globulin solution that can be administered intravenously, substantially free of contaminating viruses, by heat treatment for viral inactivation and fractionation of an impure gamma globulin solution and then treating the purified gamma globulin with a solvent-detergent for inactivation. additional viral. Gammaglobulin solution obtained by said process.

ARP980106616A 1997-12-24 1998-12-22 A PROCESS TO PREPARE A GAMMAGLOBULIN SOLUTION THAT CAN BE ADMINISTERED INTRAVENOUSLY, AND GAMMAGLOBULIN SOLUTION OBTAINED BY DICHOPROCESS AR018260A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99795297A 1997-12-24 1997-12-24

Publications (1)

Publication Number Publication Date
AR018260A1 true AR018260A1 (en) 2001-11-14

Family

ID=25544595

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980106616A AR018260A1 (en) 1997-12-24 1998-12-22 A PROCESS TO PREPARE A GAMMAGLOBULIN SOLUTION THAT CAN BE ADMINISTERED INTRAVENOUSLY, AND GAMMAGLOBULIN SOLUTION OBTAINED BY DICHOPROCESS

Country Status (15)

Country Link
EP (1) EP0971727A4 (en)
JP (1) JP2001514672A (en)
KR (1) KR20000075562A (en)
CN (1) CN1214042C (en)
AR (1) AR018260A1 (en)
AU (1) AU747893B2 (en)
BR (1) BR9807598A (en)
CA (1) CA2281938A1 (en)
CO (1) CO4970799A1 (en)
IL (1) IL131471A0 (en)
MY (1) MY117328A (en)
RU (1) RU2198668C2 (en)
TW (1) TW546144B (en)
UA (1) UA64742C2 (en)
WO (1) WO1999033484A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2421736T3 (en) * 1998-06-09 2013-09-05 Csl Behring Ag Procedure for the preparation of immunoglobulins for intravenous administration and other immunoglobulin products
IL146433A0 (en) * 1999-06-15 2002-07-25 Alpha Therapeutic Corp A process for the preparation of an intravenously-administerable gamma globulin solution
WO2002026258A2 (en) * 2000-09-28 2002-04-04 Research Corporation Technologies, Inc. Treatment of immune-mediated diseases by oral administration of plasma fractions
ES2184594B1 (en) * 2001-01-17 2004-01-01 Probitas Pharma Sa PROCEDURE FOR THE PRODUCTION OF GAMMAGLOBULINA G HUMANA INACTIVADA OF VIRUS.
US6893639B2 (en) 2001-10-19 2005-05-17 Hemacare Corporation Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
WO2004024752A1 (en) 2002-09-11 2004-03-25 Chugai Seiyaku Kabushiki Kaisha Method of purifying protein
TWI391399B (en) 2005-05-25 2013-04-01 Hoffmann La Roche Method for determining the concentration of a salt for eluting a polypeptide
KR100791502B1 (en) * 2006-09-29 2008-01-03 한스바이오메드 주식회사 Virus-Inactivated Cell-Free Implants
JP5730211B2 (en) * 2008-11-20 2015-06-03 バイオジェン アイデック エムエー インコーポレイティドＢｉｏｇｅｎ Ｉｄｅｃ Ｉｎｃ． Viral arginine inactivation
IL212911A0 (en) 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
ES2381828B1 (en) * 2012-03-20 2012-11-16 Grifols, S.A. PROCEDURE TO OBTAIN A COMPOSITION OF IgG THROUGH THERMAL TREATMENT
ES2785375T3 (en) 2014-03-11 2020-10-06 Green Cross Holdings Corp Immunoglobulin purification procedure
CN107880116B (en) * 2016-09-30 2023-02-03 盖立复集团公司 Method for producing immunoglobulins

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1064396A (en) * 1975-02-18 1979-10-16 Myer L. Coval Fractional precipitation of gamma globulin with polyethylene glycol
DE2604759C2 (en) * 1976-02-07 1983-06-01 SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld Method of Obtaining IV Compatible Gamma Globulins
SU836831A1 (en) * 1978-07-19 1982-04-23 Научно-исследовательский институт эпидемиологии и микробиологии Method for preparing immunoglobulin preparation
US4820805A (en) * 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
US4835257A (en) * 1984-07-07 1989-05-30 Armour Pharma Gmbh Process for preparing gamma globulin suitable for intravenous administration using peg and a citrate buffer
FR2582515B1 (en) * 1985-05-30 1988-11-04 Merieux Inst PROCESS FOR THE PREPARATION OF GAMMA-GOBULINS ADMINISTRABLE BY THE INTRAVENOUS ROUTE AND GAMMA-GLOBULINS OBTAINED
JPH0662436B2 (en) * 1986-05-19 1994-08-17 株式会社ミドリ十字 Method for producing intravenous immunoglobulin preparation
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
DE3641115A1 (en) * 1986-12-02 1988-06-16 Lentia Gmbh METHOD FOR PRODUCING AN INTRAVENOUS APPLICABLE AND STABLE IN LIQUID FORM IMMUNOGLOBULINS
JP2547556B2 (en) * 1987-02-06 1996-10-23 株式会社 ミドリ十字 Liquid formulation of r-globulin
DE3825429C2 (en) * 1988-07-27 1994-02-10 Biotest Pharma Gmbh Method for producing an intravenously administrable polyclonal immunoglobulin preparation with a high IgM content
DE69011136T3 (en) * 1989-01-13 2003-10-23 Mitsubishi Pharma Corp Process for the preparation of a protein-containing composition.
JP2965069B2 (en) * 1989-01-13 1999-10-18 吉富製薬株式会社 Method for producing protein-containing composition
DE69027187T2 (en) * 1989-06-15 1996-10-31 Rorer Int Overseas METHOD FOR INACTIVATING VIRUSES IN VIRUS POLLUTED PHARMACEUTICAL COMPOSITIONS
US5177194A (en) * 1990-02-01 1993-01-05 Baxter International, Inc. Process for purifying immune serum globulins
JP3145696B2 (en) * 1990-10-05 2001-03-12 日本ケミカルリサーチ株式会社 Method for producing secretory immunoglobulin A preparation
US5110910A (en) * 1991-03-25 1992-05-05 Miles Inc. Virucidal euglobulin precipitation
RU2068695C1 (en) * 1992-01-28 1996-11-10 Кировский научно-исследовательский институт гематологии и переливания крови Method of preparing immunoglobulin for intravenous administration
RU2060034C1 (en) * 1993-06-22 1996-05-20 Московский научно-исследовательский институт эпидемиологии и микробиологии им.Г.Н.Габричевского Method of immunoglobulin preparation preparing
DE4431833C1 (en) * 1994-09-07 1995-05-18 Blutspendedienst Der Drk Lande Prepn. of an anti-haemophilic factor from a cryo-precipitate
JP4003235B2 (en) * 1994-09-30 2007-11-07 三菱ウェルファーマ株式会社 Method for producing intravenous immunoglobulin preparation

Also Published As

Publication number Publication date
JP2001514672A (en) 2001-09-11
BR9807598A (en) 2000-02-22
CN1252729A (en) 2000-05-10
CA2281938A1 (en) 1999-07-08
CO4970799A1 (en) 2000-11-07
MY117328A (en) 2004-06-30
RU2198668C2 (en) 2003-02-20
EP0971727A4 (en) 2005-01-19
UA64742C2 (en) 2004-03-15
WO1999033484A1 (en) 1999-07-08
TW546144B (en) 2003-08-11
AU1703899A (en) 1999-07-19
KR20000075562A (en) 2000-12-15
CN1214042C (en) 2005-08-10
AU747893B2 (en) 2002-05-30
IL131471A0 (en) 2001-01-28
EP0971727A1 (en) 2000-01-19

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