[go: up one dir, main page]

AR017694A1 - Una composicion para la administracion nasal de un farmaco para tratar la disfuncion erectil, el uso de dicha composicion en la fabricacion de unmedicamento, y un procedimiento para la preparacion de la composicion - Google Patents

Una composicion para la administracion nasal de un farmaco para tratar la disfuncion erectil, el uso de dicha composicion en la fabricacion de unmedicamento, y un procedimiento para la preparacion de la composicion

Info

Publication number
AR017694A1
AR017694A1 ARP980106027A ARP980106027A AR017694A1 AR 017694 A1 AR017694 A1 AR 017694A1 AR P980106027 A ARP980106027 A AR P980106027A AR P980106027 A ARP980106027 A AR P980106027A AR 017694 A1 AR017694 A1 AR 017694A1
Authority
AR
Argentina
Prior art keywords
composition
procedure
drug
erectile dysfunction
nasal administration
Prior art date
Application number
ARP980106027A
Other languages
English (en)
Original Assignee
West Christopher
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9725519.4A external-priority patent/GB9725519D0/en
Priority claimed from GBGB9805253.3A external-priority patent/GB9805253D0/en
Application filed by West Christopher filed Critical West Christopher
Publication of AR017694A1 publication Critical patent/AR017694A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Una composicion para la administracion nasal que comprende un fármaco para tratar la disfuncion eréctil, en donde la composicion está adaptadapara proveer un aumento inicial en el nivel en plasma seguido de un nivel sostenido del fármaco en el plasma. Preferiblemente, el fármaco es un compuestoque tiene actividad antagonista alfa-adrenoreceptor, un compuesto que actua primariamente mediante bloqueo de la recaptacion de serotonina en lasterminales nerviosas, un compuesto con actividad antagonistadel receptor D2 central, o un inhibidor selectivo y competitiva de la V-fosfodiesterasasdel tipo c-GMP. Preferiblemente, la composicion incluye uno o más excipientes farmacéuticamente aceptables, por ejemplo un material polisacárido tal comopectina,gellan, o almidon o un copolímero de bloque tal como un poloxámero (copolímero de bloque polioxietileno-polioxipropileno) o quitosano. Seprovee también un procedimiento para elaborar estas composiciones.
ARP980106027A 1997-12-02 1998-11-27 Una composicion para la administracion nasal de un farmaco para tratar la disfuncion erectil, el uso de dicha composicion en la fabricacion de unmedicamento, y un procedimiento para la preparacion de la composicion AR017694A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9725519.4A GB9725519D0 (en) 1997-12-02 1997-12-02 Nasal formulation
GBGB9805253.3A GB9805253D0 (en) 1998-03-13 1998-03-13 Nasal formulation

Publications (1)

Publication Number Publication Date
AR017694A1 true AR017694A1 (es) 2001-09-12

Family

ID=26312701

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980106027A AR017694A1 (es) 1997-12-02 1998-11-27 Una composicion para la administracion nasal de un farmaco para tratar la disfuncion erectil, el uso de dicha composicion en la fabricacion de unmedicamento, y un procedimiento para la preparacion de la composicion

Country Status (13)

Country Link
US (2) US6342251B1 (es)
EP (1) EP1035833B1 (es)
JP (2) JP4754067B2 (es)
AR (1) AR017694A1 (es)
AT (1) ATE303131T1 (es)
AU (1) AU751182B2 (es)
CA (1) CA2312839C (es)
DE (1) DE69831421T2 (es)
DK (1) DK1035833T3 (es)
ES (1) ES2249846T3 (es)
NO (1) NO329381B1 (es)
NZ (1) NZ504786A (es)
WO (1) WO1999027905A1 (es)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566368B2 (en) * 1994-04-22 2003-05-20 Pentech Pharmaceuticals, Inc. Apomorphine-containing dosage form for ameliorating male erectile dysfunction
US7022683B1 (en) * 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
TWI223598B (en) * 1998-06-22 2004-11-11 Pfizer Ireland Pharmaceuticals An intranasal pharmaceutical composition for the treatment of male erectile dysfunction or female sexual disorders, an intranasal delivery system or device and sildenafil mesylate
US6200591B1 (en) 1998-06-25 2001-03-13 Anwar A. Hussain Method of administration of sildenafil to produce instantaneous response for the treatment of erectile dysfunction
DE19834507A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Pharmazeutische, wasserlösliche Tablettenformulierung zur Anwendung von Sildenafil
DE19834506A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Transmucosales therapeutisches System zur Anwendung von Sildenafil
US6436950B1 (en) 1998-08-14 2002-08-20 Nastech Pharmaceutical Company, Inc. Nasal delivery of apomorphine
US20020002175A1 (en) * 2000-09-19 2002-01-03 Charanjit Behl Nasal delivery of apomorphine in combination with glycol derivatives
CN1374861A (zh) * 1999-04-06 2002-10-16 佐纳根有限公司 调节人的性反应的方法
US6632419B2 (en) * 1999-05-04 2003-10-14 Aradigm Corporation Increasing libido in humans via acute testosterone administration
US7258850B2 (en) * 1999-05-04 2007-08-21 Aradigm Corporation Methods and compositions for treating erectile dysfunction
BR0005797A (pt) * 2000-03-20 2001-10-16 Abbott Lab Métodos para o tratamento de disfunção sexual com apomorfina em nìveis de concentração plasmática especificados
WO2001076602A1 (en) 2000-04-07 2001-10-18 Tap Pharmaceutical Products Inc. Apomorphine derivatives and methods for their use
JP2003534286A (ja) * 2000-05-26 2003-11-18 ホーファー リサーチ リミテッド 勃起障害症状改善のために、刺激物質の活性成分としてプロアントシアニジン、一酸化窒素源としてｌアルギニン又はその塩の使用
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US7494669B2 (en) 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
DE60223037T2 (de) 2001-08-16 2008-07-24 Cmp Therapeutics Ltd. Chitin-mikropartikel und ihre medizinische verwendung
US7666876B2 (en) 2002-03-19 2010-02-23 Vernalis (R&D) Limited Buprenorphine formulations for intranasal delivery
US20040042972A1 (en) * 2002-04-11 2004-03-04 Medimmune Vaccines, Inc. Spray freeze dry of compositions for intranasal administration
AU2003234090A1 (en) 2002-04-11 2003-10-27 Medimmune Vaccines, Inc. Spray freeze dry of compositions for pulmonary administration
WO2004003145A2 (en) * 2002-06-28 2004-01-08 Nastech Pharmaceutical Company Inc. Compositions and methods for modulating physiology of epithelial junctional adhesion molecules for enhanced mucosal delivery of therapeutic compounds
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
GB0304636D0 (en) * 2003-02-28 2003-04-02 Britannia Pharmaceuticals Ltd Pharmaceutical composition for nasal delivery
WO2004089374A1 (en) * 2003-04-14 2004-10-21 Vectura Ltd Pharmaceutical compositions comprising apomorphine for pulmonary inhalation
US20040204439A1 (en) * 2003-04-14 2004-10-14 Staniforth John Nicholas Composition, device, and method for treating sexual dysfunction via inhalation
US20040253211A1 (en) * 2003-04-30 2004-12-16 Nastech Pharmaceutical Company Inc. Method for diagnosing and treating cancer
US20050090518A1 (en) * 2003-10-24 2005-04-28 Nastech Pharmaceutical Company Inc. Method for treating parkinson's disease using apomorphine and apomorphine prodrugs
US20050129679A1 (en) * 2003-12-15 2005-06-16 Nastech Pharmaceutical Company Inc. Method for opening tight junctions
WO2006085987A2 (en) * 2004-07-09 2006-08-17 University Of Iowa Research Foundation Rna interference in respiratory epitheial cells
US20070110788A1 (en) * 2005-11-14 2007-05-17 Hissong James B Injectable formulation capable of forming a drug-releasing device
WO2008020318A2 (en) * 2006-03-30 2008-02-21 Engene, Inc. Non-viral compositions and methods for transfecting gut cells in vivo
WO2007123193A1 (ja) 2006-04-21 2007-11-01 Toko Yakuhin Kogyo Kabushiki Kaisha スプレー用ゲルタイプ皮膚・粘膜付着型製剤およびそれを用いた投与システム
GB2437488A (en) * 2006-04-25 2007-10-31 Optinose As Pharmaceutical oily formulation for nasal or buccal administration
US7993675B2 (en) * 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US7959943B2 (en) * 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US20070264296A1 (en) * 2006-05-10 2007-11-15 Myntti Matthew F Biofilm extracellular polysachharide solvating system
US7976873B2 (en) * 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
US8088095B2 (en) * 2007-02-08 2012-01-03 Medtronic Xomed, Inc. Polymeric sealant for medical use
GB0715285D0 (en) * 2007-08-06 2007-09-12 Britannia Pharmaceuticals Ltd Improvements in or relating to powdered medicaments for nasal delivery
WO2009040595A1 (en) * 2007-09-28 2009-04-02 Wockhardt Research Centre Multi-dose pharmaceutical composition of analgesic for nasal administration
GB0721394D0 (en) * 2007-10-31 2007-12-12 Vectura Group Plc Compositions for trating parkinson's disease
EP2057982A1 (en) * 2007-11-09 2009-05-13 Archimedes Development Limited Intranasal compositions
AU2009240509B2 (en) 2008-04-24 2014-08-21 Medtronic, Inc. Rehydratable thiolated polysaccharide particles and sponge
JP5833919B2 (ja) * 2008-04-24 2015-12-16 メドトロニック，インコーポレイテッド キトサンと酸化多糖とに基づく保護用ゲル
ES2619515T3 (es) 2008-04-24 2017-06-26 Medtronic, Inc Partículas de polisacárido rehidratables y esponja
EP2296637B1 (en) 2008-04-24 2014-04-02 Medtronic, Inc Chitosan-containing protective composition
CA2727432C (en) 2008-06-12 2016-10-11 Medtronic Xomed, Inc. Method for treating chronic wounds with an extracellular polymeric substance solvating system
US8580801B2 (en) 2008-07-23 2013-11-12 Robert I. Henkin Phosphodiesterase inhibitor treatment
US20100086576A1 (en) * 2008-10-06 2010-04-08 Myntti Matthew F Antimicrobial composition and methods of making and using same
CZ302789B6 (cs) 2009-11-25 2011-11-09 Zentiva, K. S. Zpusob zvýšení rozpustnosti farmaceuticky aktivních látek a cílený (kontrolovaný) transport do streva
US10653133B2 (en) 2011-05-10 2020-05-19 Next Science IP Holdings Pty Ltd Antimicrobial solid and methods of making and using same
MX2016001030A (es) 2013-07-23 2016-10-07 Allergan Inc Métodos y composiciones que comprenden desmopresina en combinación con un agonista del receptor beta 3-adrenérgico.
EP3108245B1 (en) 2014-02-18 2020-07-22 Robert I. Henkin Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
EP3220942B1 (en) * 2014-11-20 2022-04-27 Serenity Pharmaceuticals LLC Compositions comprising low dose desmopressin in combination with an alpha-adrenergic receptor antagonist
FR3032618A1 (fr) * 2015-02-12 2016-08-19 Laboratoires Chemineau Composition a base de plantes de la famille des malvaceae pour une administration dans la cavite nasale
EP3056219B1 (fr) * 2015-02-12 2018-08-22 Laboratoires Chemineau Composition à base de plantes de la famille des malvaceae pour une administration sur les muqueuses
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
KR20240134157A (ko) * 2022-01-06 2024-09-06 시라노 테라퓨틱스, 아이엔씨. 파킨슨 치료제의 개선된 코 투여

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62123112A (ja) 1985-11-22 1987-06-04 Sunstar Inc 軟膏基剤
DE3601132A1 (de) 1986-01-16 1987-07-23 Christian Bannert Verfahren zur behandlung der schleimhaut
JPS62236862A (ja) 1986-04-09 1987-10-16 Nippon Kayaku Co Ltd 人工粘液
JPH01501708A (ja) * 1987-01-08 1989-06-15 ナステツク　フアーマスーテイカル　カンパニー，インコーポレイテツド アミノ酸の経鼻投与
US4826683A (en) * 1987-01-09 1989-05-02 Bates Harry L Decongestant
FR2614021B1 (fr) * 1987-04-14 1991-03-01 Andre Buzas Derives de la 1-((1,1-diphenyl)-1-alcenyl)-piperazine, procede d'obtention et compositions pharmaceutiques les contenant
US4915948A (en) 1987-08-31 1990-04-10 Warner-Lambert Company Tablets having improved bioadhesion to mucous membranes
DE3827561C1 (es) 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
US5707644A (en) * 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
JPH0436233A (ja) * 1990-05-29 1992-02-06 Biomaterial Universe Kk 生理活性物質含有生体内分解吸収性の徐放性製剤
JPH0597706A (ja) 1991-04-09 1993-04-20 Chemex Block Drug Jv アフタ性潰瘍および他の粘膜皮膚障害の処置方法
IT1250691B (it) * 1991-07-22 1995-04-21 Giancarlo Santus Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.
US5318780A (en) 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
DK0689438T3 (da) * 1993-03-26 2003-09-29 Franciscus Wilhelmus He Merkus Farmaceutiske præparater til intranasal administration af apomorfin
EP0696919B1 (en) * 1993-04-05 2002-01-30 Competitive Technologies, Inc. Diagnosis and treatment of erectile dysfunction
NZ250844A (en) * 1993-04-07 1996-03-26 Pfizer Treatment of non-insulin dependant diabetes with peptides; composition
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
CA2167081A1 (en) * 1993-07-12 1995-01-26 Alexander K. Andrianov Hydrogel microencapsulated vaccines
JP3696265B2 (ja) * 1994-02-04 2005-09-14 日本オルガノン株式会社 点鼻液剤
DE10199068I2 (de) * 1994-04-22 2004-05-06 Pentech Pharmaceuticals Inc Sublinguale Dosierungsformen enthaltend apomorphinzur Verwendung bei der Behandlung von erektiler D ysfunktion.
GB9414966D0 (en) * 1994-07-26 1994-09-14 Danbiosyst Uk Pharmaceutical compositions for the nasal administration of antiviral agents
GB9707934D0 (en) * 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces

Also Published As

Publication number Publication date
DE69831421T2 (de) 2006-06-22
AU1253599A (en) 1999-06-16
NO20002851L (no) 2000-06-02
NO20002851D0 (no) 2000-06-02
ATE303131T1 (de) 2005-09-15
DK1035833T3 (da) 2006-01-09
NO329381B1 (no) 2010-10-04
EP1035833B1 (en) 2005-08-31
JP2001524509A (ja) 2001-12-04
US20010046519A1 (en) 2001-11-29
EP1035833A1 (en) 2000-09-20
JP4754067B2 (ja) 2011-08-24
WO1999027905A1 (en) 1999-06-10
US6342251B1 (en) 2002-01-29
DE69831421D1 (de) 2005-10-06
AU751182B2 (en) 2002-08-08
JP2011026341A (ja) 2011-02-10
NZ504786A (en) 2005-07-29
CA2312839A1 (en) 1999-06-10
ES2249846T3 (es) 2006-04-01
CA2312839C (en) 2008-01-15

Similar Documents

Publication Publication Date Title
AR017694A1 (es) Una composicion para la administracion nasal de un farmaco para tratar la disfuncion erectil, el uso de dicha composicion en la fabricacion de unmedicamento, y un procedimiento para la preparacion de la composicion
PT954314E (pt) Formas de dosagem farmaceutica para melhorar a disfuncao erectil masculina
AR005281A1 (es) Composicion farceutica oral , procedimientos para su manufactura y uso de esa composicion farmaceutica para la preparacion de medicamentos. .
EA200700049A1 (ru) Препаративные формы оральных лекарственных форм мемантина с модифицированным высвобождением
AR018410A1 (es) Uso de una composicion para la manufactura de un medicamento que se usa para la prevencion o tratamiento de un estado agudo de asma y/o asma intermitentey/o episodios de asma cronico y metodo para la prevencion o tratamiento de un estado agudo de asma y/o asma intermitente y/o episodios de asma cron
ES2177780T3 (es) Medicamentos para el tratamiento de enfermedades autoinmunes usando interferon tau.
AR013117A1 (es) Una composicion farmaceutica solida en forma de comprimido que comprende un derivado de benzofurano con actividad antiarritmica adaptada para administracion oral
PT828500E (pt) Utilizacao de flavanolignanos para a preparacao de medicamentos com actividade antiproliferativa no utero ovarios e mama
RU2008113439A (ru) Композиции с замедленным высвобождением лекарственного средства
ES2246567T3 (es) Composiciones para receptores inhibidores de celulas t y usos de las mismas.
AR020015A1 (es) Composiciones de celecoxib
AR032152A1 (es) Uso de una combinacion de compuestos terapeuticos organicos para la fabricacion de un medicamento, un agente terapeutico, y una composicion farmaceutica
AR040248A1 (es) Farmaco para el tratamiento de la vejiga hiperactiva
NZ517038A (en) Use of serotonin reuptake inihibitor in medicaments for treating sexual dysfunction
AR022909A1 (es) Sinergia entre heparina de bajo peso molecular e inhibidores de la agregacion plaquetaria, que provee una terapia combinada para la prevencion ytratamiento de diversas afecciones tromboembolicas
ECSP034826A (es) Método para fabricar una composición farmacéutica de dosis baja
AR019699A1 (es) Composicion farmaceutica para el tratamiento de disfuncion de la evacuacion y uso de la misma para la preparacion de un agente terapeutico
AR046036A1 (es) Composiciones de risedronato y metodos para su uso
PE20011049A1 (es) Combinacion de farmacos para el tratamiento de la depresion y trastornos relacionados que comprenden mirtazapina
ATE311928T1 (de) (-)-pseudoephedrin als sympathomimetisches arzneimittel
ES2194618T1 (es) Composicion oralmente desintegrable que comprende mirtazapina.
AR046146A1 (es) Formulaciones farmaceuticas transdermicas para pulverizacion que comprenden un agente activo, un copolimero de vp/va y un vehiculo no acuoso
AR057242A2 (es) Composicion farmaceutica para administracion oral y uso de la misma en la fabricacion de un medicamento
AR034142A1 (es) Una composicion farmaceutica, metodo para fabricar un medicamento en base a dicha composicion y uso de la composicion
HRP20020258B1 (hr) Farmaceutska kombinacija etinilestradiola i drospirenona za upotrebu kao kontracepcijskog sredstva