[go: up one dir, main page]

AP2008004485A0 - Preparation of gamma-amino acids having affinity for the alpha-2-delta protein - Google Patents

Preparation of gamma-amino acids having affinity for the alpha-2-delta protein

Info

Publication number
AP2008004485A0
AP2008004485A0 AP2008004485A AP2008004485A AP2008004485A0 AP 2008004485 A0 AP2008004485 A0 AP 2008004485A0 AP 2008004485 A AP2008004485 A AP 2008004485A AP 2008004485 A AP2008004485 A AP 2008004485A AP 2008004485 A0 AP2008004485 A0 AP 2008004485A0
Authority
AP
ARIPO
Prior art keywords
gamma
affinity
alpha
preparation
amino acids
Prior art date
Application number
AP2008004485A
Other languages
English (en)
Inventor
Margaret Claire Evans
Lloyd Charles Franklin
Lorraine Michelle Et A Murtach
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IB2006/003668 external-priority patent/WO2007072163A2/fr
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AP2008004485A0 publication Critical patent/AP2008004485A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30Preparation of optical isomers
    • C07C227/32Preparation of optical isomers by stereospecific synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/002Nitriles (-CN)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/005Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AP2008004485A 2005-12-21 2006-12-11 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein AP2008004485A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75283905P 2005-12-21 2005-12-21
PCT/IB2006/003668 WO2007072163A2 (fr) 2005-12-20 2006-12-07 Derives de pyrimidine

Publications (1)

Publication Number Publication Date
AP2008004485A0 true AP2008004485A0 (en) 2008-06-30

Family

ID=37903526

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2008004485A AP2008004485A0 (en) 2005-12-21 2006-12-11 Preparation of gamma-amino acids having affinity for the alpha-2-delta protein

Country Status (28)

Country Link
US (2) US20070141684A1 (fr)
EP (2) EP2017259A3 (fr)
JP (1) JP2009520492A (fr)
KR (1) KR20080068932A (fr)
CN (1) CN101341117A (fr)
AP (1) AP2008004485A0 (fr)
AR (1) AR058559A1 (fr)
AU (1) AU2006327872A1 (fr)
BR (1) BRPI0620467A2 (fr)
CA (1) CA2633358A1 (fr)
CR (1) CR10080A (fr)
DO (1) DOP2006000286A (fr)
EA (1) EA200801393A1 (fr)
EC (1) ECSP088551A (fr)
GT (1) GT200600524A (fr)
IL (1) IL191840A0 (fr)
MA (1) MA30139B1 (fr)
ME (1) ME00005B (fr)
NL (1) NL2000374C2 (fr)
NO (1) NO20082989L (fr)
NZ (1) NZ568971A (fr)
PE (1) PE20071169A1 (fr)
RS (1) RS20080279A (fr)
TN (1) TNSN08272A1 (fr)
TW (1) TW200736201A (fr)
UY (1) UY30031A1 (fr)
WO (1) WO2007072159A1 (fr)
ZA (1) ZA200804780B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009248750B2 (en) * 2008-05-21 2015-05-21 Sandoz Ag Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester
EP2571867B1 (fr) 2010-05-21 2015-11-04 Noviga Research AB Nouveaux dérivés de pyrimidine
FR2966734B1 (fr) * 2010-10-29 2014-07-18 Max Rombi Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides
KR20140006048A (ko) 2011-03-24 2014-01-15 케밀리아 에이비 신규한 피리미딘 유도체
CN102249833B (zh) * 2011-05-27 2013-12-11 中国科学院化学研究所 一种制备手性γ-氨基酸及其衍生物的方法
WO2017155025A1 (fr) * 2016-03-10 2017-09-14 第一三共株式会社 Procédé de production de dérivés optiquement actifs de l'acide valérique par résolution optique au moyen d'une enzyme
CN108192932B (zh) * 2017-12-26 2020-09-29 上海皓元生物医药科技有限公司 一种手性醇的酶催化制备方法
CN112877219A (zh) * 2021-01-29 2021-06-01 江西科技师范大学 一种高浓度胆固醇培养基及其制备方法和应用
CN119462461B (zh) * 2024-12-06 2025-11-04 万华化学集团股份有限公司 一种维生素a异构化的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5618710A (en) 1990-08-03 1997-04-08 Vertex Pharmaceuticals, Inc. Crosslinked enzyme crystals
GB9518953D0 (en) 1995-09-15 1995-11-15 Pfizer Ltd Pharmaceutical formulations
WO2000035298A1 (fr) 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Chewing-gum contenant des agents medicamenteux actifs
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
CA2689997A1 (fr) * 1999-06-10 2000-12-21 Warner-Lambert Company Llc Acides 3-propyle gamma-aminobutyriques monosubstitues et disubstitues
US6642398B2 (en) * 1999-06-10 2003-11-04 Warner-Lambert Company Mono-and disubstituted 3-propyl gamma-aminobutyric acids
EP1572188A1 (fr) 2002-12-13 2005-09-14 Warner-Lambert Company LLC Derives de pregabalin pour le traitement de la fibromyalgie et d'autres troubles
UA82292C2 (uk) * 2004-04-14 2008-03-25 Пфайзер Продактс Инк. Спосіб стереоселективного біоперетворення аліфатичних динітрилів в ціанокарбонові кислоти (варіанти)

Also Published As

Publication number Publication date
DOP2006000286A (es) 2007-07-31
ZA200804780B (en) 2009-05-27
WO2007072159A1 (fr) 2007-06-28
NL2000374A1 (nl) 2007-06-25
CN101341117A (zh) 2009-01-07
ME00005B (fr) 2010-06-10
EP2017259A2 (fr) 2009-01-21
WO2007072159B1 (fr) 2008-08-21
EP1973867A1 (fr) 2008-10-01
AR058559A1 (es) 2008-02-13
TW200736201A (en) 2007-10-01
EA200801393A1 (ru) 2009-12-30
NL2000374C2 (nl) 2010-02-09
IL191840A0 (en) 2008-12-29
JP2009520492A (ja) 2009-05-28
TNSN08272A1 (fr) 2009-10-30
BRPI0620467A2 (pt) 2011-11-16
MEP0708A (xx) 2010-02-10
UY30031A1 (es) 2007-07-31
ECSP088551A (es) 2008-07-30
GT200600524A (es) 2007-12-03
US20070141684A1 (en) 2007-06-21
NZ568971A (en) 2010-04-30
KR20080068932A (ko) 2008-07-24
AU2006327872A1 (en) 2007-06-28
RS20080279A (sr) 2009-07-15
CA2633358A1 (fr) 2007-06-28
CR10080A (es) 2008-07-10
PE20071169A1 (es) 2007-11-30
EP2017259A3 (fr) 2011-04-13
US20090299093A1 (en) 2009-12-03
NO20082989L (no) 2008-09-19
MA30139B1 (fr) 2009-01-02

Similar Documents

Publication Publication Date Title
IL187191A0 (en) Incorporation of non-naturally encoded amino acids into proteins
ZA200804780B (en) Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
ZA200902008B (en) Dextran functionalized with hydrophobic amino acids
IL197681A0 (en) Dextran functionalized with hydrophobic amino acids
ZA200803448B (en) Preparation of canola protein isolate involving isoelectric precipitation
EP1988922A4 (fr) Formulations de protéines
PL1874770T3 (pl) Fenyloacetamidy odpowiednie jako inhibitory kinaz białkowych
PL1999259T3 (pl) Specyficzne miejscowo wprowadzanie aminokwasów do cząsteczek
IL185547A0 (en) Lipocalin protein
IL205238A0 (en) Directed evolution using proteins comprising unnatural amino acids
ZA200800899B (en) Production of canola protein
ZA200804611B (en) Methods for the use of branched chain amino acids
EP1932533A4 (fr) Composition pour l'amélioration du métabolisme des lipides corporels
EP1868434A4 (fr) Acides beta-lactamylalcanoiques destines au traitement des troubles premenstruels
GB0611116D0 (en) Proteins
EP1922345A4 (fr) Procede destine a la preparation d'un copolymere-1
GB0626021D0 (en) The stabilisation of proteins
ZA200800348B (en) Derivatives of seleno-amino acids
GB0601976D0 (en) Proteins
ZA200708652B (en) Purification of proteins with cationic surfactant
ZA200707238B (en) Preparation of optically pure beta-amino acids having affinity for the alpha-2-delta protein
ZA200710664B (en) Processes for the preparation of docetaxel
IL187855A0 (en) Processes for the preparation of docetaxel
IL179851A0 (en) Preparation of beta-amino acids having affinity for the alpha-2-delta protein
GB0505419D0 (en) High affinity purification of protein complexes