OA13165A - (2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl-phenyl derivatives as beta2 agonists. - Google Patents

(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl-phenyl derivatives as beta2 agonists. Download PDF

Info

Publication number: OA13165A
Authority: OA; OAPI
Prior art keywords: hydroxy; phenyl; propyl; hydroxymethyl; amino
Prior art date: 2003-05-15

Application number

OA1200500317A

Other languages

English (en)

Inventor

Mark Edward Bunnage

Paul Alan Glossop

Charlotte Alice Louise Lane

Russell Andrew Lewthwaite

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-15

Filing date

2004-04-29

Publication date

2006-12-13

2004-04-29 Application filed by Pfizer filed Critical Pfizer

2006-12-13 Publication of OA13165A publication Critical patent/OA13165A/en

Links

229940124748 beta 2 agonist Drugs 0.000 title claims description 24
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125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 205
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125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 15
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229940083542 sodium Drugs 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
235000015424 sodium Nutrition 0.000 description 1
235000010413 sodium alginate Nutrition 0.000 description 1
239000000661 sodium alginate Substances 0.000 description 1
229940005550 sodium alginate Drugs 0.000 description 1
URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
BEOOHQFXGBMRKU-UHFFFAOYSA-N sodium cyanoborohydride Chemical compound [Na+].[B-]C#N BEOOHQFXGBMRKU-UHFFFAOYSA-N 0.000 description 1
239000008109 sodium starch glycolate Substances 0.000 description 1
229920003109 sodium starch glycolate Polymers 0.000 description 1
229940079832 sodium starch glycolate Drugs 0.000 description 1
229940045902 sodium stearyl fumarate Drugs 0.000 description 1
239000007901 soft capsule Substances 0.000 description 1
239000006104 solid solution Substances 0.000 description 1
235000019337 sorbitan trioleate Nutrition 0.000 description 1
229960000391 sorbitan trioleate Drugs 0.000 description 1
238000001694 spray drying Methods 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
239000000758 substrate Substances 0.000 description 1
KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
235000000346 sugar Nutrition 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
229910021653 sulphate ion Inorganic materials 0.000 description 1
239000000829 suppository Substances 0.000 description 1
239000002511 suppository base Substances 0.000 description 1
239000000375 suspending agent Substances 0.000 description 1
230000002459 sustained effect Effects 0.000 description 1
230000009747 swallowing Effects 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
230000001975 sympathomimetic effect Effects 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
230000005062 synaptic transmission Effects 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000007916 tablet composition Substances 0.000 description 1
230000006794 tachycardia Effects 0.000 description 1
108060008037 tachykinin Proteins 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
229940095064 tartrate Drugs 0.000 description 1
229950004351 telenzepine Drugs 0.000 description 1
125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
150000003512 tertiary amines Chemical class 0.000 description 1
125000001302 tertiary amino group Chemical group 0.000 description 1
239000010409 thin film Substances 0.000 description 1
125000005490 tosylate group Chemical class 0.000 description 1
229940074410 trehalose Drugs 0.000 description 1
COIOYMYWGDAQPM-UHFFFAOYSA-N tri(ortho-tolyl)phosphine Substances CC1=CC=CC=C1P(C=1C(=CC=CC=1)C)C1=CC=CC=C1C COIOYMYWGDAQPM-UHFFFAOYSA-N 0.000 description 1
YNDXUCZADRHECN-JNQJZLCISA-N triamcinolone acetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O YNDXUCZADRHECN-JNQJZLCISA-N 0.000 description 1
229960002117 triamcinolone acetonide Drugs 0.000 description 1
RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical compound C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 description 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
229910052722 tritium Inorganic materials 0.000 description 1
229960000281 trometamol Drugs 0.000 description 1
229960005356 urokinase Drugs 0.000 description 1
230000002792 vascular Effects 0.000 description 1
239000005526 vasoconstrictor agent Substances 0.000 description 1
239000003981 vehicle Substances 0.000 description 1
229920001567 vinyl ester resin Polymers 0.000 description 1
239000003871 white petrolatum Substances 0.000 description 1
150000003751 zinc Chemical class 0.000 description 1
239000011701 zinc Substances 0.000 description 1
229910052725 zinc Inorganic materials 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/14—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Indole Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

OA1200500317A 2003-05-15 2004-04-29 (2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl-phenyl derivatives as beta2 agonists. OA13165A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03010944A EP1477167A1 (en)	2003-05-15	2003-05-15	[(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivatives as beta2 agonists
GBGB0329874.2A GB0329874D0 (en)	2003-05-15	2003-12-23	Compounds useful for the treatment of diseases

Publications (1)

Publication Number	Publication Date
OA13165A true OA13165A (en)	2006-12-13

Family

ID=33454327

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200500317A OA13165A (en)	2003-05-15	2004-04-29	(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl-phenyl derivatives as beta2 agonists.

Country Status (29)

Country	Link
EP (2)	EP1477167A1 (da)
JP (1)	JP3966897B2 (da)
KR (1)	KR100749990B1 (da)
CN (1)	CN1791407A (da)
AP (1)	AP2005003443A0 (da)
AR (1)	AR044335A1 (da)
AT (1)	ATE413879T1 (da)
AU (1)	AU2004237952A1 (da)
BR (1)	BRPI0410391A (da)
CA (1)	CA2525006A1 (da)
CL (1)	CL2004000963A1 (da)
CO (1)	CO5700776A2 (da)
DE (1)	DE602004017710D1 (da)
DK (1)	DK1624868T3 (da)
EA (1)	EA200501615A1 (da)
EC (1)	ECSP056164A (da)
ES (1)	ES2314395T3 (da)
GB (1)	GB0329874D0 (da)
IS (1)	IS8080A (da)
MA (1)	MA27840A1 (da)
MX (1)	MXPA05012329A (da)
NL (1)	NL1026203C2 (da)
NO (1)	NO20055854L (da)
OA (1)	OA13165A (da)
PA (1)	PA8603001A1 (da)
PE (1)	PE20060095A1 (da)
TW (1)	TW200505865A (da)
UY (1)	UY28317A1 (da)
WO (1)	WO2004100950A1 (da)

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PT1708992E (pt)	2004-01-22	2007-11-16	Pfizer	Derivados de sulfonamida para o tratamento de doenças
NZ548318A (en)	2004-01-22	2009-03-31	Pfizer	Sulfonamide derivatives for the treatment of diseases
EA200601510A1 (ru) *	2004-03-17	2007-04-27	Пфайзер Инк.	Производные фенилэтаноламина в качестве бета-2-агонистов
EP1730141B1 (en) *	2004-03-23	2009-05-27	Pfizer Limited	Compounds for the treatment of diseases
WO2005092860A1 (en) *	2004-03-23	2005-10-06	Pfizer Limited	Compounds for the treatment of diseases
PE20060272A1 (es)	2004-05-24	2006-05-22	Glaxo Group Ltd	(2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
UA87854C2 (en)	2004-06-07	2009-08-25	Мерк Энд Ко., Инк.	N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
GB0424284D0 (en)	2004-11-02	2004-12-01	Novartis Ag	Organic compounds
GB0514809D0 (en)	2005-07-19	2005-08-24	Glaxo Group Ltd	Compounds
GB0516313D0 (en)	2005-08-08	2005-09-14	Argenta Discovery Ltd	Azole derivatives and their uses
EP2281813A1 (en)	2005-08-08	2011-02-09	Pulmagen Therapeutics (Synergy) Limited	Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses
GB0601951D0 (en)	2006-01-31	2006-03-15	Novartis Ag	Organic compounds
US20100041662A1 (en)	2006-10-30	2010-02-18	Sandrine Ferrand	Heterocyclic compounds as antiinflammatory agents
WO2009087224A1 (en)	2008-01-11	2009-07-16	Novartis Ag	Pyrimidines as kinase inhibitors
US8236786B2 (en)	2008-08-07	2012-08-07	Pulmagen Therapeutics (Inflammation) Limited	Respiratory disease treatment
PL2379507T3 (pl)	2008-12-30	2014-03-31	Pulmagen Therapeutics Inflammation Ltd	Związki sulfonamidu do leczenia zaburzeń układu oddechowego
WO2010150014A1 (en)	2009-06-24	2010-12-29	Pulmagen Therapeutics (Inflammation) Limited	5r- 5 -deuterated glitazones for respiratory disease treatment
GB201002224D0 (en)	2010-02-10	2010-03-31	Argenta Therapeutics Ltd	Respiratory disease treatment
UY33597A (es)	2010-09-09	2012-04-30	Irm Llc	Compuestos y composiciones como inhibidores de la trk
WO2012034095A1 (en)	2010-09-09	2012-03-15	Irm Llc	Compounds and compositions as trk inhibitors
JP5959541B2 (ja)	2011-02-25	2016-08-02	ノバルティスアーゲー	Ｔｒｋ阻害剤としてのピラゾロ［１，５−ａ］ピリジン
GB201601301D0 (en) *	2016-01-25	2016-03-09	Takeda Pharmaceutical	Novel compounds

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GB8528633D0 (en) *	1985-11-21	1985-12-24	Beecham Group Plc	Compounds
US5629200A (en) *	1993-11-18	1997-05-13	Daicel Chemical Industries, Ltd.	Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation
US5561142A (en) *	1994-04-26	1996-10-01	Merck & Co., Inc.	Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity
WO1996035671A1 (en) *	1995-05-10	1996-11-14	Pfizer Inc.	β-ADRENERGIC AGONISTS
US6090942A (en) *	1998-10-15	2000-07-18	Pfizer Inc.	Process and intermediates for a β3 -adrenergic receptor agonist

2003
- 2003-05-15 EP EP03010944A patent/EP1477167A1/en not_active Withdrawn
- 2003-12-23 GB GBGB0329874.2A patent/GB0329874D0/en not_active Ceased
2004
- 2004-04-29 MX MXPA05012329A patent/MXPA05012329A/es unknown
- 2004-04-29 CA CA002525006A patent/CA2525006A1/en not_active Abandoned
- 2004-04-29 WO PCT/IB2004/001519 patent/WO2004100950A1/en not_active Ceased
- 2004-04-29 DE DE602004017710T patent/DE602004017710D1/de not_active Expired - Fee Related
- 2004-04-29 EA EA200501615A patent/EA200501615A1/ru unknown
- 2004-04-29 CN CNA2004800132433A patent/CN1791407A/zh active Pending
- 2004-04-29 KR KR1020057021707A patent/KR100749990B1/ko not_active Expired - Fee Related
- 2004-04-29 AU AU2004237952A patent/AU2004237952A1/en not_active Abandoned
- 2004-04-29 JP JP2006530636A patent/JP3966897B2/ja not_active Expired - Fee Related
- 2004-04-29 DK DK04730338T patent/DK1624868T3/da active
- 2004-04-29 AT AT04730338T patent/ATE413879T1/de not_active IP Right Cessation
- 2004-04-29 AP AP2005003443A patent/AP2005003443A0/xx unknown
- 2004-04-29 OA OA1200500317A patent/OA13165A/en unknown
- 2004-04-29 EP EP04730338A patent/EP1624868B9/en not_active Expired - Lifetime
- 2004-04-29 BR BRPI0410391-2A patent/BRPI0410391A/pt not_active IP Right Cessation
- 2004-04-29 ES ES04730338T patent/ES2314395T3/es not_active Expired - Lifetime
- 2004-05-05 CL CL200400963A patent/CL2004000963A1/es unknown
- 2004-05-11 PE PE2004000483A patent/PE20060095A1/es not_active Application Discontinuation
- 2004-05-12 UY UY28317A patent/UY28317A1/es not_active Application Discontinuation
- 2004-05-13 PA PA20048603001A patent/PA8603001A1/es unknown
- 2004-05-14 NL NL1026203A patent/NL1026203C2/nl active Search and Examination
- 2004-05-14 TW TW093113677A patent/TW200505865A/zh unknown
- 2004-05-14 AR ARP040101650A patent/AR044335A1/es not_active Application Discontinuation
2005
- 2005-10-20 IS IS8080A patent/IS8080A/is unknown
- 2005-11-09 CO CO05113616A patent/CO5700776A2/es not_active Application Discontinuation
- 2005-11-15 EC EC2005006164A patent/ECSP056164A/es unknown
- 2005-11-15 MA MA28609A patent/MA27840A1/fr unknown
- 2005-12-09 NO NO20055854A patent/NO20055854L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES2314395T3 (es)	2009-03-16
CO5700776A2 (es)	2006-11-30
ECSP056164A (es)	2006-04-19
UY28317A1 (es)	2004-12-31
KR20060017607A (ko)	2006-02-24
ATE413879T1 (de)	2008-11-15
NL1026203C2 (nl)	2005-07-26
KR100749990B1 (ko)	2007-08-16
GB0329874D0 (en)	2004-01-28
JP3966897B2 (ja)	2007-08-29
BRPI0410391A (pt)	2006-07-18
PA8603001A1 (es)	2004-12-16
CN1791407A (zh)	2006-06-21
DK1624868T3 (da)	2009-02-23
EP1624868A1 (en)	2006-02-15
EP1477167A1 (en)	2004-11-17
MXPA05012329A (es)	2006-01-30
EA200501615A1 (ru)	2006-06-30
IS8080A (is)	2005-10-20
EP1624868B1 (en)	2008-11-12
NO20055854L (no)	2006-02-10
NL1026203A1 (nl)	2004-11-16
DE602004017710D1 (de)	2008-12-24
CL2004000963A1 (es)	2005-03-18
WO2004100950A1 (en)	2004-11-25
AU2004237952A1 (en)	2004-11-25
MA27840A1 (fr)	2006-04-03
JP2007503458A (ja)	2007-02-22
PE20060095A1 (es)	2006-02-18
CA2525006A1 (en)	2004-11-25
EP1624868B9 (en)	2009-08-12
TW200505865A (en)	2005-02-16
AP2005003443A0 (en)	2005-12-31
AR044335A1 (es)	2005-09-07

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