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NO951640D0 - Antimicrobial 5-hydrazinoquinolone derivatives - Google Patents

Antimicrobial 5-hydrazinoquinolone derivatives

Info

Publication number
NO951640D0
NO951640D0 NO951640A NO951640A NO951640D0 NO 951640 D0 NO951640 D0 NO 951640D0 NO 951640 A NO951640 A NO 951640A NO 951640 A NO951640 A NO 951640A NO 951640 D0 NO951640 D0 NO 951640D0
Authority
NO
Norway
Prior art keywords
hydrazinoquinolone
antimicrobial
derivatives
hydrazinoquinolone derivatives
Prior art date
Application number
NO951640A
Other languages
Norwegian (no)
Other versions
NO951640L (en
Inventor
Jr Thomas Prosser Demuth
Ronald Eugene White
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO951640D0 publication Critical patent/NO951640D0/en
Publication of NO951640L publication Critical patent/NO951640L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO951640A 1992-10-30 1995-04-28 Antimicrobial 5-hydrazinoquinolone derivatives NO951640L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96896092A 1992-10-30 1992-10-30
PCT/US1993/010091 WO1994010163A1 (en) 1992-10-30 1993-10-22 Antimicrobial 5-hydrazino-quinolone derivatives

Publications (2)

Publication Number Publication Date
NO951640D0 true NO951640D0 (en) 1995-04-28
NO951640L NO951640L (en) 1995-06-30

Family

ID=25514997

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951640A NO951640L (en) 1992-10-30 1995-04-28 Antimicrobial 5-hydrazinoquinolone derivatives

Country Status (21)

Country Link
EP (1) EP0666853A1 (en)
JP (1) JPH08502750A (en)
KR (1) KR950704301A (en)
CN (1) CN1064357C (en)
AU (1) AU687018B2 (en)
BR (1) BR9307347A (en)
CA (1) CA2148003A1 (en)
CZ (1) CZ282581B6 (en)
EG (1) EG20543A (en)
FI (1) FI952049A7 (en)
HU (1) HUT72072A (en)
IL (1) IL107323A (en)
MX (1) MX9306814A (en)
NO (1) NO951640L (en)
NZ (1) NZ257470A (en)
PL (1) PL178094B1 (en)
RU (1) RU2126000C1 (en)
SG (1) SG59979A1 (en)
SK (1) SK54795A3 (en)
WO (1) WO1994010163A1 (en)
ZA (1) ZA938089B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
JPH10503521A (en) * 1994-08-02 1998-03-31 ザ、プロクター、エンド、ギャンブル、カンパニー Method for producing quinolonyl lactam antimicrobial agent and novel intermediate compound
EP0775114B1 (en) * 1994-08-02 2000-03-22 The Procter & Gamble Company Process for making antimicrobial compounds
DE69717970T2 (en) * 1996-02-09 2003-04-30 Toyama Chemical Co. Ltd., Tokio/Tokyo CHINOLINE CARBONIC DERIVATIVES AND THEIR SALTS
RU2248199C1 (en) * 2003-06-02 2005-03-20 Открытое Акционерное Общество "Акционерное Курганское общество медицинских препаратов и изделий "Синтез" (ОАО "Синтез") Eye drops and method for their obtaining
RU2265437C2 (en) * 2003-07-02 2005-12-10 Суханов Александр Владимирович Method for treating gastric and duodenal diseases caused by helicobacter pylori
RU2245134C1 (en) * 2003-09-02 2005-01-27 Открытое акционерное общество "Красфарма" Ofloxacine composition for injections
DK1666477T3 (en) 2003-09-10 2013-07-29 Kyorin Seiyaku Kk 7- (4-TRISUBSTITUTED 3-CYCLOPROPYLAMINOMETHYL-1-PYRROLIDINYL) -QUINOLONCARBOXYLIC ACID DERIVATE
PL1901749T3 (en) * 2005-05-18 2017-04-28 Horizon Orphan Llc Aerosolized fluoroquinolones and uses thereof
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
EE05697B1 (en) 2005-06-08 2014-02-17 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
EA010601B1 (en) * 2005-06-09 2008-10-30 Янссен Фармацевтика Н.В. Quinoline derivatives as antibacterial agents
CN101020647B (en) * 2007-02-14 2011-03-30 杭州师范学院 A kind of synthetic method of β-cyclopropylaminoacrylic acid (ester)
JP5363350B2 (en) * 2007-03-19 2013-12-11 武田薬品工業株式会社 MAPK / ERK kinase inhibitor
PT3092901T (en) * 2007-10-05 2020-05-21 Senhwa Biosciences Inc Quinolone analogs and methods related thereto
US8349829B2 (en) * 2008-06-03 2013-01-08 Actelion Pharmaceuticals Ltd. [4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl)-tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials
CA2739897C (en) 2008-10-07 2017-10-03 Mpex Pharmaceuticals, Inc. Aerosol fluoroquinolone formulations for improved pharmacokinetics
US8629139B2 (en) 2008-10-07 2014-01-14 Mpex Pharmaceuticals, Inc. Topical use of Levofloxacin for reducing lung inflammation
AR076222A1 (en) * 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EP2473170B1 (en) 2009-09-04 2019-06-19 Horizon Orphan LLC Use of aerosolized levofloxacin for treating cystic fibrosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
JPH0228178A (en) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd Novel pyridonecarboxylic acid derivative and salt thereof
DE3906365A1 (en) * 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
PL166381B1 (en) * 1989-08-16 1995-05-31 Pfizer Method for the production of new substituted 7-azabicycloquinolone carboxylic acids PL PL PL PL
DE69132256T2 (en) * 1990-04-18 2001-01-25 Procter & Gamble Pharmaceuticals, Inc. ANTIMICROBIAL CHINOLONYL LACTAME
JPH06503565A (en) * 1990-11-30 1994-04-21 ワーナー−ランバート・コンパニー Individual stereoisomers of 7-[3-(aminoalkyl)-1-pyrrolidinyl]-quinolone and naphthyridone as antibacterial agents

Also Published As

Publication number Publication date
CA2148003A1 (en) 1994-05-11
PL308671A1 (en) 1995-08-21
AU687018B2 (en) 1998-02-19
CZ282581B6 (en) 1997-08-13
RU95110762A (en) 1997-01-10
AU5409794A (en) 1994-05-24
IL107323A (en) 2000-06-01
SG59979A1 (en) 1999-02-22
HU9501237D0 (en) 1995-06-28
BR9307347A (en) 1999-05-25
FI952049L (en) 1995-04-28
HUT72072A (en) 1996-03-28
CZ109795A3 (en) 1995-12-13
MX9306814A (en) 1994-07-29
EP0666853A1 (en) 1995-08-16
JPH08502750A (en) 1996-03-26
KR950704301A (en) 1995-11-17
ZA938089B (en) 1994-06-07
PL178094B1 (en) 2000-02-29
WO1994010163A1 (en) 1994-05-11
CN1092773A (en) 1994-09-28
IL107323A0 (en) 1994-01-25
NO951640L (en) 1995-06-30
EG20543A (en) 1999-07-31
SK54795A3 (en) 1995-12-06
FI952049A0 (en) 1995-04-28
RU2126000C1 (en) 1999-02-10
NZ257470A (en) 1997-08-22
CN1064357C (en) 2001-04-11
FI952049A7 (en) 1995-04-28

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