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NO810765L - Fremgangsmaate for fremstilling av farmasoeytisk aktive karbostyrilderivater. - Google Patents

Fremgangsmaate for fremstilling av farmasoeytisk aktive karbostyrilderivater.

Info

Publication number
NO810765L
NO810765L NO810765A NO810765A NO810765L NO 810765 L NO810765 L NO 810765L NO 810765 A NO810765 A NO 810765A NO 810765 A NO810765 A NO 810765A NO 810765 L NO810765 L NO 810765L
Authority
NO
Norway
Prior art keywords
pharmasoyytic
carbostyric
derivatives
procedure
active
Prior art date
Application number
NO810765A
Other languages
English (en)
Other versions
NO159531B (no
NO159531C (no
Inventor
Kazuo Banno
Takafumi Fujioka
Masaaki Osaki
Kazuyuki Nakagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2880580A external-priority patent/JPS56125370A/ja
Priority claimed from JP11502280A external-priority patent/JPS5738772A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO810765L publication Critical patent/NO810765L/no
Publication of NO159531B publication Critical patent/NO159531B/no
Publication of NO159531C publication Critical patent/NO159531C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO810765A 1980-03-06 1981-03-05 Analogifremgangsmaate for fremstilling av farmasoeytisk aktive karbostyrilderivater. NO159531C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2880580A JPS56125370A (en) 1980-03-06 1980-03-06 Carbostyril derivative
JP11502280A JPS5738772A (en) 1980-08-20 1980-08-20 Carbostyril derivative

Publications (3)

Publication Number Publication Date
NO810765L true NO810765L (no) 1981-09-07
NO159531B NO159531B (no) 1988-10-03
NO159531C NO159531C (no) 1989-01-11

Family

ID=26366952

Family Applications (1)

Application Number Title Priority Date Filing Date
NO810765A NO159531C (no) 1980-03-06 1981-03-05 Analogifremgangsmaate for fremstilling av farmasoeytisk aktive karbostyrilderivater.

Country Status (21)

Country Link
US (4) US4567187A (no)
AT (1) AT381307B (no)
AU (1) AU523005B2 (no)
BE (1) BE887800A (no)
CA (1) CA1155119A (no)
CH (1) CH647775A5 (no)
DE (2) DE3107601A1 (no)
DK (1) DK155282C (no)
ES (4) ES500137A0 (no)
FI (1) FI76323C (no)
FR (1) FR2477542A1 (no)
GB (1) GB2071094B (no)
IT (1) IT1144315B (no)
MX (1) MX6980E (no)
NL (1) NL184364C (no)
NO (1) NO159531C (no)
PH (1) PH17194A (no)
PT (1) PT72622B (no)
RU (1) RU1779249C (no)
SE (1) SE447255B (no)
SU (1) SU1367857A3 (no)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FI77852C (fi) * 1981-02-17 1989-05-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat.
AU532361B2 (en) * 1981-09-01 1983-09-29 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
US4578381A (en) * 1982-07-05 1986-03-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
CH655110A5 (de) * 1982-09-03 1986-03-27 Otsuka Pharma Co Ltd Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
DE3434271A1 (de) * 1984-09-19 1986-03-20 Beiersdorf Ag, 2000 Hamburg Substituierte 3,4-dihydro-chinolin-2(1h)-one verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
DE3509131A1 (de) * 1985-03-14 1986-09-18 Fa. Carl Zeiss, 7920 Heidenheim Verfahren zur justierten montage der optischen bauteile eines optischen geraetes
US4704390A (en) * 1986-02-13 1987-11-03 Warner-Lambert Company Phenyl and heterocyclic tetrahydropyridyl alkoxy-benzheterocyclic compounds as antipsychotic agents
DK167187A (da) * 1986-04-02 1987-10-03 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse
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US4792561A (en) * 1986-05-29 1988-12-20 Syntex (U.S.A.) Inc. Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
JPH0696555B2 (ja) * 1986-07-31 1994-11-30 大塚製薬株式会社 カルボスチリル誘導体
US4886809A (en) * 1986-07-31 1989-12-12 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof
DE3802030A1 (de) * 1988-01-25 1989-07-27 Hoechst Ag Makroporoese, asymmetrische, hydrophile membran aus polyaramid
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
FR2634206B1 (fr) * 1988-07-12 1992-05-15 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2 et quinoleinones-2, leur preparation et leur application en therapeutique
FR2637591B1 (fr) * 1988-10-11 1992-10-23 Synthelabo Derives de quinoleinone, leur preparation et leur application en therapeutique
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US5147881A (en) * 1990-11-14 1992-09-15 Pfizer Inc 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents
US5166367A (en) * 1991-06-21 1992-11-24 American Home Products Corporation Antipsychotic benzodioxan derivatives
US5189171A (en) * 1991-06-21 1993-02-23 American Home Products Corporation Antipsychotic benzodioxan derivatives
RU2065859C1 (ru) * 1991-07-17 1996-08-27 Пфайзер Инк. Производные 2-(4-гидроксипиперидино)-1-алканола и производные 2-(4-гидроксипиперидино)-1-алканона
US6255322B1 (en) 1992-06-19 2001-07-03 Pfizer Inc. 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents
KR100238346B1 (ko) * 1993-04-07 2000-03-02 오쓰까 아끼히꼬 피페리딘 유도체를 유효성분으로 하는 말초혈관확장제
EP0709384B1 (de) * 1994-10-31 1998-12-23 MERCK PATENT GmbH Benzylpiperidinderivate mit hoher Affinität zu Bindungsstellen von Aminosäure-Rezeptoren
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610741B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
DE19812331A1 (de) * 1998-03-20 1999-09-23 Merck Patent Gmbh Piperidinderivate
FR2823749B1 (fr) * 2001-04-20 2004-02-20 Sanofi Synthelabo Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant
MY129350A (en) * 2001-04-25 2007-03-30 Bristol Myers Squibb Co Aripiprazole oral solution
DE10210779A1 (de) * 2002-03-12 2003-10-09 Merck Patent Gmbh Cyclische Amide
ES2347544T3 (es) 2002-03-13 2010-11-02 Janssen Pharmaceutica Nv Inhibidores de histona-desacetilasas.
OA12788A (en) * 2002-03-13 2006-07-10 Janssen Pharmaceutica Nv Piperazinyl-, piperidinyl- and morpholinyl-derivatives as novel inhibitors of histone deacetylase.
KR20040094672A (ko) 2002-03-13 2004-11-10 얀센 파마슈티카 엔.브이. 히스톤 디아세틸라제의 신규한 저해제로서의설포닐아미노-유도체
EP1485348B1 (en) * 2002-03-13 2008-06-11 Janssen Pharmaceutica N.V. Carbonylamino-derivatives as novel inhibitors of histone deacetylase
MY142362A (en) * 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis
CN1993356B (zh) * 2004-07-28 2010-10-27 詹森药业有限公司 作为组蛋白脱乙酰基酶新颖抑制剂的取代丙烯基哌嗪衍生物
ME01058B (me) * 2004-07-28 2012-10-20 Janssen Pharmaceutica Nv Supstituisani derivati propenil piperazina kao novi inhibitori histonske deacetilaze
AU2005266312C1 (en) 2004-07-28 2011-06-16 Janssen Pharmaceutica N.V. Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
CA2605272C (en) 2005-05-18 2013-12-10 Janssen Pharmaceutica N.V. Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase
DE602007001190D1 (de) * 2006-01-19 2009-07-09 Janssen Pharmaceutica Nv Aminophenylderivate als neue inhibitoren von histondeacetylase
EP1979327A1 (en) * 2006-01-19 2008-10-15 Janssen Pharmaceutica, N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
CA2635015C (en) * 2006-01-19 2014-06-03 Janssen Pharmaceutica N.V. Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase
DK1979326T3 (da) * 2006-01-19 2013-01-07 Janssen Pharmaceutica Nv Pyridin- og pyrimidinderivater som inhibitorer af histondeacetylase
EP1988077A4 (en) * 2006-02-23 2009-09-02 Shionogi & Co NUCLEIC HETEROCYCLIC DERIVATIVES SUBSTITUTED BY CYCLIC GROUPS
WO2009034029A2 (de) * 2007-09-07 2009-03-19 Boehringer Ingelheim International Gmbh 1-substituierte 4 -heterocyclylpiperidine als cgrp antagonisten
ES2605232T3 (es) 2009-02-26 2017-03-13 Reviva Pharmaceuticals, Inc. Composiciones, síntesis y métodos de utilización de derivados de arilpiperazina
US9951088B2 (en) * 2012-05-09 2018-04-24 Sunovion Pharmaceuticals Inc. D2 receptor modulators and methods of use thereof in the treatment of diseases and disorders
CN106608875A (zh) 2015-10-26 2017-05-03 江苏恩华药业股份有限公司 一种稠和杂环类衍生物合成及其应用
CN108031471A (zh) * 2017-10-27 2018-05-15 苏州盖德精细材料有限公司 一种静电纺丝制备的负载型纳米纤维催化剂及其在3,5-二羟基甲苯制备中的应用
CN108250058B (zh) * 2018-01-19 2022-02-11 上海怡立舍生物技术有限公司 Ppar激动剂及其在治疗老年痴呆及其他疾病中的用途
CN116554127B (zh) * 2022-01-28 2025-03-21 成都麻沸散医药科技有限公司 哌嗪取代苯酚类衍生物及其用途

Family Cites Families (33)

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US3629266A (en) * 1969-03-03 1971-12-21 Miles Lab (phenyl piperidino alkyl)3 4-dihydrocarbostyrils
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
JPS5239035B2 (no) * 1972-12-14 1977-10-03
US4068076A (en) * 1972-12-29 1978-01-10 Otsuka Pharmaceutical Co., Ltd. 5-(1-Hydroxy-2-(heterocyclic amino))ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
US4022784A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
US4022776A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives
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JPS5527158A (en) * 1978-08-16 1980-02-27 Otsuka Pharmaceut Co Ltd 5-oxo-3,4,5,6,7,8-hexahydrocarbostyril derivative
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FI77852C (fi) * 1981-02-17 1989-05-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat.
AU532361B2 (en) * 1981-09-01 1983-09-29 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives

Also Published As

Publication number Publication date
ES518667A0 (es) 1984-06-16
ES8306141A1 (es) 1983-05-01
BE887800A (fr) 1981-09-07
FR2477542B1 (no) 1983-09-09
NL184364C (nl) 1989-07-03
US4455422A (en) 1984-06-19
FI810669L (fi) 1981-09-07
GB2071094B (en) 1984-09-26
NL184364B (nl) 1989-02-01
AU6797381A (en) 1981-09-10
NO159531B (no) 1988-10-03
DK155282C (da) 1989-08-07
ES8301962A1 (es) 1982-11-01
DK155282B (da) 1989-03-20
ES8305356A1 (es) 1983-04-01
ES500137A0 (es) 1982-11-01
MX6980E (es) 1987-01-19
NL8101099A (nl) 1981-10-01
FR2477542A1 (fr) 1981-09-11
US4460593A (en) 1984-07-17
DE3107601A1 (de) 1982-02-04
SE8101409L (sv) 1981-09-07
SU1367857A3 (ru) 1988-01-15
US4567187A (en) 1986-01-28
PH17194A (en) 1984-06-19
DK99781A (da) 1981-09-07
FI76323B (fi) 1988-06-30
CH647775A5 (de) 1985-02-15
AT381307B (de) 1986-09-25
PT72622A (en) 1981-04-01
DE3152880C2 (no) 1990-03-22
NO159531C (no) 1989-01-11
GB2071094A (en) 1981-09-16
IT8167311A0 (it) 1981-03-05
CA1155119A (en) 1983-10-11
ES509659A0 (es) 1983-05-01
FI76323C (fi) 1988-10-10
AU523005B2 (en) 1982-07-08
US4619932A (en) 1986-10-28
ATA98481A (de) 1986-02-15
DE3107601C2 (no) 1989-07-20
RU1779249C (ru) 1992-11-30
PT72622B (en) 1982-06-15
ES509658A0 (es) 1983-04-01
ES8405782A1 (es) 1984-06-16
SE447255B (sv) 1986-11-03
IT1144315B (it) 1986-10-29

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