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NO2543724T3 - - Google Patents

Info

Publication number
NO2543724T3
NO2543724T3 NO12165189A NO12165189A NO2543724T3 NO 2543724 T3 NO2543724 T3 NO 2543724T3 NO 12165189 A NO12165189 A NO 12165189A NO 12165189 A NO12165189 A NO 12165189A NO 2543724 T3 NO2543724 T3 NO 2543724T3
Authority
NO
Norway
Application number
NO12165189A
Other languages
Norwegian (no)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP08450052A external-priority patent/EP2108695A1/fr
Application filed filed Critical
Publication of NO2543724T3 publication Critical patent/NO2543724T3/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813Exopeptidases (3.4.11. to 3.4.19)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485Exopeptidases (3.4.11-3.4.19)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/17Metallocarboxypeptidases (3.4.17)
    • C12Y304/17023Angiotensin-converting enzyme 2 (3.4.17.23)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO12165189A 2007-06-12 2008-06-12 NO2543724T3 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT0091307A AT505262A1 (de) 2007-06-12 2007-06-12 Rekombinantes ace2 polypeptid
EP08450052A EP2108695A1 (fr) 2008-04-08 2008-04-08 Polypeptide Ace2
EP08756821.8A EP2155871B1 (fr) 2007-06-12 2008-06-12 Polypeptide ace2
EP12165189.7A EP2543724B1 (fr) 2007-06-12 2008-06-12 Polypeptide Ace2

Publications (1)

Publication Number Publication Date
NO2543724T3 true NO2543724T3 (fr) 2018-08-18

Family

ID=39720296

Family Applications (1)

Application Number Title Priority Date Filing Date
NO12165189A NO2543724T3 (fr) 2007-06-12 2008-06-12

Country Status (35)

Country Link
US (3) US8586319B2 (fr)
EP (3) EP3375872A1 (fr)
JP (1) JP5731193B2 (fr)
KR (2) KR101682240B1 (fr)
CN (2) CN104450654A (fr)
AT (1) AT505262A1 (fr)
AU (1) AU2008261591B2 (fr)
BR (1) BRPI0813942B8 (fr)
CA (1) CA2692854C (fr)
CO (1) CO6270265A2 (fr)
CR (1) CR11213A (fr)
CY (2) CY1116873T1 (fr)
DK (2) DK2543724T3 (fr)
DO (1) DOP2009000282A (fr)
EA (1) EA027399B1 (fr)
EG (1) EG27095A (fr)
ES (2) ES2670938T3 (fr)
HK (1) HK1255493A1 (fr)
HR (2) HRP20151120T1 (fr)
HU (2) HUE028012T2 (fr)
IL (1) IL202653B (fr)
LT (1) LT2543724T (fr)
MA (1) MA31472B1 (fr)
MX (1) MX2009013472A (fr)
MY (1) MY180672A (fr)
NO (1) NO2543724T3 (fr)
NZ (1) NZ581704A (fr)
PL (2) PL2543724T3 (fr)
PT (2) PT2155871E (fr)
RS (2) RS57292B1 (fr)
SI (2) SI2543724T1 (fr)
TR (1) TR201808117T4 (fr)
UA (1) UA106869C2 (fr)
WO (1) WO2008151347A1 (fr)
ZA (1) ZA200908751B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10221228B2 (en) 2006-02-03 2019-03-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US20140113860A1 (en) 2006-02-03 2014-04-24 Prolor Biotech Ltd. Long-acting polypeptides and methods of producing and administering same
US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US10351615B2 (en) 2006-02-03 2019-07-16 Opko Biologics Ltd. Methods of treatment with long-acting growth hormone
US8048849B2 (en) 2006-02-03 2011-11-01 Modigene, Inc. Long-acting polypeptides and methods of producing same
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US20150038413A1 (en) 2006-02-03 2015-02-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US8946155B2 (en) 2006-02-03 2015-02-03 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
AT505262A1 (de) * 2007-06-12 2008-12-15 Apeiron Biolog Forschungs Und Rekombinantes ace2 polypeptid
EP2077119A1 (fr) * 2007-12-21 2009-07-08 Apeiron Biologics Forschungs- und Entwicklungsgesellschaft M.B.H. Traitement de fibroses et de maladies du foie
AT506632A1 (de) * 2008-04-09 2009-10-15 Apeiron Biolog Forschungs Und Behandlung von tumorerkrankungen
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
US12203113B2 (en) 2009-07-09 2025-01-21 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
WO2013157002A1 (fr) 2012-04-19 2013-10-24 Prolor Biotech Inc. Variants d'oxyntomoduline à action prolongée et procédés pour les produire
RU2015106812A (ru) 2012-08-02 2016-09-27 Ф.Хоффманн-Ля Рош Аг Способ получения мономерных и мультимерных молекул и их применение
EA033788B1 (ru) 2012-11-20 2019-11-26 Opko Biologics Ltd Способ увеличения гидродинамического объема полипептида путем присоединения карбоксиконцевого пептида гонадотропина
KR20150110607A (ko) * 2013-01-14 2015-10-02 아페이론 바이오로직스 아게 변형된 ace2 폴리펩티드
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
CN107438623B (zh) 2014-12-10 2023-07-14 Opko生物科学有限公司 长效的ctp修饰的生长激素多肽的制备方法
HUE055449T2 (hu) 2015-06-19 2021-11-29 Opko Biologics Ltd Hosszú hatástartamú koagulációs faktorok és eljárások ezek elõállítására
TW202444744A (zh) 2016-07-11 2024-11-16 以色列商歐科生物製品有限公司 長效型凝血因子及其生產方法
US11518788B2 (en) * 2020-07-10 2022-12-06 Avirus, Inc. Methods and compositions for treating and preventing viral infection
WO2021151043A2 (fr) * 2020-01-23 2021-07-29 Jang Hyun Han Méthodes et compositions de traitement et de prévention d'infections virales
WO2021190980A1 (fr) 2020-03-22 2021-09-30 Quadrucept Bio Limited Multimères pour l'évolution d'une souche virale
EP3884957A1 (fr) 2020-03-26 2021-09-29 The University of British Columbia Procédés de traitement de virus et procédés de criblage de réactif anti-virus à l'aide d'organoïdes
US20230293647A1 (en) * 2020-04-09 2023-09-21 Autolus Limited Polypeptide
WO2021217120A2 (fr) * 2020-04-24 2021-10-28 Administrators Of The Tulane Educational Fund Compositions et procédés visant à prévenir ou réduire les effets d'infections par des coronavirus qui se lient au domaine extracellulaire du récepteur ace2
CN113667016A (zh) * 2020-05-15 2021-11-19 普米斯生物技术(珠海)有限公司 一种构建冠状病毒抗体的平台
WO2021247675A1 (fr) 2020-06-02 2021-12-09 Ngm Biopharmaceuticals, Inc. Agents liant les coronavirus et leurs utilisations
DE102020207224A1 (de) 2020-06-09 2021-12-09 Christoph Karle Protein oder Peptid, insbesondere zur Prophylaxe und/oder Behandlung einer durch Coronaviren, insbesondere SARS-CoV-2-Viren, hervorgerufenen Infektion oder Infektionskrankheit und/oder einer Folgekrankheit davon
EP4171603A4 (fr) * 2020-06-25 2024-06-26 Gliknik Inc. Protéines de fusion ace2-fc et méthodes d'utilisation
WO2022008642A1 (fr) 2020-07-08 2022-01-13 Apeiron Biologics Ag Traitement d'une infection par le sras-cov-2 avec une combinaison de cibles
KR20230066317A (ko) * 2020-07-10 2023-05-15 바이오몰레큘러 홀딩스 엘엘씨 사면체 항체
US20240035012A1 (en) * 2020-08-21 2024-02-01 Westlake University Engineered ace2 oligomers and uses thereof
KR102725210B1 (ko) * 2020-10-05 2024-11-04 한양대학교 산학협력단 안정화된 Ace2 변이체, 이를 이용한 Ace2-Fc 융합단백질 및 COVID-19 예방 또는 치료용 약학 조성물
CN112280764A (zh) * 2020-11-18 2021-01-29 通用生物系统(安徽)有限公司 一种新冠重组ace2蛋白在哺乳动物细胞中的生产方法
EP4011387A1 (fr) 2020-12-11 2022-06-15 IMBA-Institut für Molekulare Biotechnologie GmbH Neutralisation supérieure du sars-cov-2 par la conversion de l'enzyme 2 de l'angiotensine humaine déglycosylée
US20220226489A1 (en) 2021-01-20 2022-07-21 Singh Biotechnology, Llc Therapeutics directed against coronavirus
WO2022184659A1 (fr) 2021-03-01 2022-09-09 Quadrucept Bio Limited Domaines d'anticorps et multimères
WO2022207918A1 (fr) 2021-04-02 2022-10-06 Apeiron Biologics Ag Thérapie anti-covid-19
EP4387732A4 (fr) 2021-08-19 2025-09-03 Phenom Pharmaceuticals Inc Compositions et méthodes pour le traitement du sars-cov-2
KR102834587B1 (ko) * 2021-09-16 2025-07-17 인에이블앱 주식회사 안지오텐신전환효소 2 수용체 및 이의 용도
CN113897346A (zh) * 2021-09-16 2022-01-07 四川大学 能够提高与SARS-CoV-2 S蛋白亲和力的ACE2突变组合及应用
DE102023118690A1 (de) 2023-07-14 2025-01-16 Christoph Karle Protein oder Peptid, insbesondere zur Prophylaxe und/oder Behandlung einer Infektion und/oder Infektionskrankheit und/oder einer Folgeerkrankung davon

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610497B1 (en) * 1997-12-11 2003-08-26 Millennium Pharmaceuticals, Inc. Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor
US6194556B1 (en) * 1997-12-11 2001-02-27 Millennium Pharmaceuticals, Inc. Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor
US6989363B1 (en) * 1997-12-11 2006-01-24 Millennium Pharmaceuticals, Inc. Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor
DE60324925D1 (de) 2002-06-19 2009-01-08 Univ Health Network Ace2-aktivierung zur behandlung von herz, lungen, und nierenkrankheit und bluthochdruck
WO2004023270A2 (fr) 2002-09-09 2004-03-18 Millenium Pharmaceuticals, Inc. Structure cristalline de la carboxypeptidase liee a l'enzyme convertissant l'angiotensine
EP1723962A1 (fr) * 2005-05-19 2006-11-22 IMBA-Institut für Molekulare Biotechnologie GmbH Utilisation des inhibiteurs du système de rénine-angiotensine pour le traitement des lesions poumonaires.
AT504443B1 (de) 2006-10-19 2008-11-15 Apeiron Biolog Forschungs Und Verfahren zur bestimmung der aktivität von ace2
AT505262A1 (de) * 2007-06-12 2008-12-15 Apeiron Biolog Forschungs Und Rekombinantes ace2 polypeptid
EP2108695A1 (fr) 2008-04-08 2009-10-14 Apeiron Biologics Forschungs- und Entwicklungsgesellschaft M.B.H. Polypeptide Ace2
AT506258A1 (de) * 2007-12-18 2009-07-15 Apeiron Biolog Forschungs Und Behandlung inflammatorischer krankheiten
AT506632A1 (de) * 2008-04-09 2009-10-15 Apeiron Biolog Forschungs Und Behandlung von tumorerkrankungen

Also Published As

Publication number Publication date
TR201808117T4 (tr) 2018-07-23
SI2155871T1 (sl) 2015-11-30
HRP20180856T1 (hr) 2018-08-24
US8586319B2 (en) 2013-11-19
EP2155871A1 (fr) 2010-02-24
CR11213A (es) 2010-04-20
RS57292B1 (sr) 2018-08-31
EP2543724A3 (fr) 2013-02-20
CY1120426T1 (el) 2019-07-10
JP5731193B2 (ja) 2015-06-10
HUE037877T2 (hu) 2018-09-28
ZA200908751B (en) 2010-07-28
KR20160054045A (ko) 2016-05-13
MA31472B1 (fr) 2010-06-01
US20180289779A1 (en) 2018-10-11
WO2008151347A1 (fr) 2008-12-18
EA027399B1 (ru) 2017-07-31
BRPI0813942A2 (pt) 2014-12-30
CN101796183A (zh) 2010-08-04
HK1136602A1 (en) 2010-07-02
BRPI0813942B8 (pt) 2021-05-25
CN104450654A (zh) 2015-03-25
LT2543724T (lt) 2018-06-25
PL2543724T3 (pl) 2018-08-31
UA106869C2 (uk) 2014-10-27
US10716833B2 (en) 2020-07-21
RS54340B1 (sr) 2016-02-29
PT2543724T (pt) 2018-06-11
JP2011519264A (ja) 2011-07-07
CA2692854C (fr) 2017-07-04
CA2692854A1 (fr) 2008-12-18
AT505262A1 (de) 2008-12-15
MY180672A (en) 2020-12-05
EP2155871B1 (fr) 2015-08-12
NZ581704A (en) 2012-05-25
CY1116873T1 (el) 2017-04-05
DOP2009000282A (es) 2010-03-31
IL202653A0 (en) 2011-08-01
CO6270265A2 (es) 2011-04-20
ES2670938T3 (es) 2018-06-04
IL202653B (en) 2018-01-31
EP2543724B1 (fr) 2018-03-21
BRPI0813942B1 (pt) 2019-08-20
MX2009013472A (es) 2010-06-25
ES2550390T3 (es) 2015-11-06
SI2543724T1 (en) 2018-07-31
DK2543724T3 (en) 2018-05-28
US20100310546A1 (en) 2010-12-09
DK2155871T3 (en) 2015-11-09
EP2543724A2 (fr) 2013-01-09
HRP20151120T1 (xx) 2015-11-20
US20140099297A1 (en) 2014-04-10
HK1255493A1 (zh) 2019-08-16
AU2008261591A1 (en) 2008-12-18
PL2155871T3 (pl) 2015-12-31
KR20100040809A (ko) 2010-04-21
EA201000002A1 (ru) 2010-08-30
PT2155871E (pt) 2015-10-26
AU2008261591B2 (en) 2014-08-07
HUE028012T2 (en) 2016-11-28
EP3375872A1 (fr) 2018-09-19
KR101682240B1 (ko) 2016-12-06
EG27095A (en) 2015-05-28

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