NO20092655L - 2-quinolinone and 2-quinoxalinone derivatives and their use as antibacterial agents - Google Patents
2-quinolinone and 2-quinoxalinone derivatives and their use as antibacterial agentsInfo
- Publication number
- NO20092655L NO20092655L NO20092655A NO20092655A NO20092655L NO 20092655 L NO20092655 L NO 20092655L NO 20092655 A NO20092655 A NO 20092655A NO 20092655 A NO20092655 A NO 20092655A NO 20092655 L NO20092655 L NO 20092655L
- Authority
- NO
- Norway
- Prior art keywords
- quinolinone
- antibacterial agents
- quinoxalinone derivatives
- quinoxalinone
- derivatives
- Prior art date
Links
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- FFRYUAVNPBUEIC-UHFFFAOYSA-N quinoxalin-2-ol Chemical class C1=CC=CC2=NC(O)=CN=C21 FFRYUAVNPBUEIC-UHFFFAOYSA-N 0.000 title 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Foreliggende oppfinnelse angår forbindelser med formel (I), og farmasøytisk akseptable salter derav, deres anvendelse ved behandling av bakterielle infeksjoner og deres fremgangsmåter for fremstilling.The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, to their use in treating bacterial infections and to their methods of preparation.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87018106P | 2006-12-15 | 2006-12-15 | |
| US96916307P | 2007-08-30 | 2007-08-30 | |
| PCT/GB2007/004766 WO2008071961A1 (en) | 2006-12-15 | 2007-12-13 | 2-quinolinone and 2-quinoxalinone- derivatives and their use as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20092655L true NO20092655L (en) | 2009-09-02 |
Family
ID=39046831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20092655A NO20092655L (en) | 2006-12-15 | 2009-07-13 | 2-quinolinone and 2-quinoxalinone derivatives and their use as antibacterial agents |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP2121702A1 (en) |
| JP (1) | JP2010513255A (en) |
| KR (1) | KR20090090385A (en) |
| AR (1) | AR064369A1 (en) |
| AU (1) | AU2007331247B2 (en) |
| BR (1) | BRPI0720236A2 (en) |
| CA (1) | CA2671485A1 (en) |
| CL (1) | CL2007003641A1 (en) |
| CO (1) | CO6190619A2 (en) |
| EC (1) | ECSP099506A (en) |
| MX (1) | MX2009006325A (en) |
| NO (1) | NO20092655L (en) |
| PE (1) | PE20081511A1 (en) |
| RU (1) | RU2009126731A (en) |
| TW (1) | TW200831517A (en) |
| UY (1) | UY30788A1 (en) |
| WO (1) | WO2008071961A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| WO2006137485A1 (en) | 2005-06-24 | 2006-12-28 | Toyama Chemical Co., Ltd. | Novel nitrogenated heterocyclic compound and salt thereof |
| EP1992628A1 (en) | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| WO2010041218A2 (en) | 2008-10-10 | 2010-04-15 | Actelion Pharmaceuticals Ltd | Oxazolidinyl antibiotics |
| AR076222A1 (en) | 2009-04-09 | 2011-05-26 | Actelion Pharmaceuticals Ltd | DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| US20130259899A1 (en) * | 2010-10-04 | 2013-10-03 | Allen-Vercoe, Emma Molecular And Cellular Biology University Of Guelph | Detection of fusobacterium in a gastrointestinal sample to diagnose gastrointestinal cancer |
| SG11202001062XA (en) | 2017-08-21 | 2020-03-30 | Acadia Pharm Inc | Compounds, salts thereof and methods for treatment of diseases |
| WO2019040104A2 (en) * | 2017-08-21 | 2019-02-28 | Acadia Pharmaceuticals Inc. | Compounds, salts thereof and methods for treatment of diseases |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19601265A1 (en) * | 1996-01-16 | 1997-07-17 | Bayer Ag | 2-oxo and 2-thio-1,2-dihydroquinolinyl oxazolidinones |
| AR040336A1 (en) | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | PIPERIDINE COMPOUND, USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND PROCEDURE TO PREPARE SUCH COMPOUND |
| JP5314244B2 (en) * | 2004-10-27 | 2013-10-16 | 富山化学工業株式会社 | Novel nitrogen-containing heterocyclic compounds and salts thereof |
| MY150958A (en) * | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| WO2006137485A1 (en) * | 2005-06-24 | 2006-12-28 | Toyama Chemical Co., Ltd. | Novel nitrogenated heterocyclic compound and salt thereof |
| KR101409261B1 (en) * | 2006-05-26 | 2014-06-18 | 다이쇼 세이야꾸 가부시끼가이샤 | Novel heterocyclic compound or salt thereof and intermediate thereof |
| US20100256124A1 (en) * | 2006-06-09 | 2010-10-07 | David Thomas Davies | Substituted 1-Methyl-1H-Quinolin-2-Ones And 1-Methyl-1H-1,5-Naphthyridin-2-Ones As Antibacterials |
| GB0613208D0 (en) * | 2006-07-03 | 2006-08-09 | Glaxo Group Ltd | Compounds |
| EP1992628A1 (en) * | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| NZ573644A (en) * | 2006-07-20 | 2011-09-30 | Glaxo Group Ltd | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones |
-
2007
- 2007-12-12 TW TW096147437A patent/TW200831517A/en unknown
- 2007-12-13 WO PCT/GB2007/004766 patent/WO2008071961A1/en not_active Ceased
- 2007-12-13 CA CA002671485A patent/CA2671485A1/en not_active Abandoned
- 2007-12-13 UY UY30788A patent/UY30788A1/en unknown
- 2007-12-13 MX MX2009006325A patent/MX2009006325A/en not_active Application Discontinuation
- 2007-12-13 JP JP2009540854A patent/JP2010513255A/en active Pending
- 2007-12-13 RU RU2009126731/04A patent/RU2009126731A/en not_active Application Discontinuation
- 2007-12-13 KR KR1020097014660A patent/KR20090090385A/en not_active Withdrawn
- 2007-12-13 BR BRPI0720236-9A2A patent/BRPI0720236A2/en not_active IP Right Cessation
- 2007-12-13 EP EP07848510A patent/EP2121702A1/en not_active Withdrawn
- 2007-12-13 AU AU2007331247A patent/AU2007331247B2/en not_active Expired - Fee Related
- 2007-12-14 PE PE2007001798A patent/PE20081511A1/en not_active Application Discontinuation
- 2007-12-14 CL CL200703641A patent/CL2007003641A1/en unknown
- 2007-12-14 AR ARP070105641A patent/AR064369A1/en not_active Application Discontinuation
-
2009
- 2009-07-02 CO CO09068489A patent/CO6190619A2/en not_active Application Discontinuation
- 2009-07-09 EC EC2009009506A patent/ECSP099506A/en unknown
- 2009-07-13 NO NO20092655A patent/NO20092655L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007331247A1 (en) | 2008-06-19 |
| EP2121702A1 (en) | 2009-11-25 |
| WO2008071961A1 (en) | 2008-06-19 |
| KR20090090385A (en) | 2009-08-25 |
| CL2007003641A1 (en) | 2008-09-22 |
| WO2008071961A8 (en) | 2009-10-22 |
| CA2671485A1 (en) | 2008-06-19 |
| PE20081511A1 (en) | 2008-12-12 |
| TW200831517A (en) | 2008-08-01 |
| JP2010513255A (en) | 2010-04-30 |
| RU2009126731A (en) | 2011-01-20 |
| ECSP099506A (en) | 2009-08-28 |
| AU2007331247B2 (en) | 2011-10-20 |
| BRPI0720236A2 (en) | 2013-12-24 |
| AR064369A1 (en) | 2009-04-01 |
| CO6190619A2 (en) | 2010-08-19 |
| UY30788A1 (en) | 2008-07-31 |
| MX2009006325A (en) | 2009-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |