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NO20085422L - Bindingsproteiner for hepatocyttvekstfaktor (HGF) - Google Patents

Bindingsproteiner for hepatocyttvekstfaktor (HGF)

Info

Publication number
NO20085422L
NO20085422L NO20085422A NO20085422A NO20085422L NO 20085422 L NO20085422 L NO 20085422L NO 20085422 A NO20085422 A NO 20085422A NO 20085422 A NO20085422 A NO 20085422A NO 20085422 L NO20085422 L NO 20085422L
Authority
NO
Norway
Prior art keywords
hgf
binding proteins
growth factor
hepatocyte growth
activity
Prior art date
Application number
NO20085422A
Other languages
English (en)
Norwegian (no)
Inventor
May Han
S Kirk Wright
Jr William M Winston
Lyne Breault
Jie Lin
Bijan Etemad-Gilbertson
Christine Knuehl
Jeno Gyuris
Original Assignee
Aveo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aveo Pharmaceuticals Inc filed Critical Aveo Pharmaceuticals Inc
Publication of NO20085422L publication Critical patent/NO20085422L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO20085422A 2006-06-02 2008-12-30 Bindingsproteiner for hepatocyttvekstfaktor (HGF) NO20085422L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81071406P 2006-06-02 2006-06-02
US86046106P 2006-11-21 2006-11-21
PCT/US2007/012950 WO2007143098A2 (fr) 2006-06-02 2007-06-01 Protéines de liaison au facteur de croissance des cellules hépatiques (hgf)

Publications (1)

Publication Number Publication Date
NO20085422L true NO20085422L (no) 2009-02-27

Family

ID=38802082

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085422A NO20085422L (no) 2006-06-02 2008-12-30 Bindingsproteiner for hepatocyttvekstfaktor (HGF)

Country Status (15)

Country Link
US (5) US7659378B2 (fr)
EP (2) EP2029627B1 (fr)
JP (2) JP4560582B2 (fr)
KR (1) KR101196184B1 (fr)
AR (1) AR061170A1 (fr)
AT (1) ATE533787T1 (fr)
AU (1) AU2007254853B2 (fr)
BR (1) BRPI0712223A2 (fr)
CA (1) CA2654019A1 (fr)
ES (1) ES2378097T3 (fr)
IL (2) IL195038A0 (fr)
MX (1) MX2008015138A (fr)
NO (1) NO20085422L (fr)
NZ (1) NZ573819A (fr)
WO (1) WO2007143098A2 (fr)

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US20090123946A1 (en) * 2007-10-19 2009-05-14 Abbott Laboratories Immunoassays and kits for the detection of ngal
US8846036B2 (en) 2007-10-19 2014-09-30 Abbott Laboratories Antibodies that bind to mammalian NGAL and uses thereof
US20100260668A1 (en) * 2008-04-29 2010-10-14 Abbott Laboratories Dual Variable Domain Immunoglobulins and Uses Thereof
CN102076355B (zh) 2008-04-29 2014-05-07 Abbvie公司 双重可变结构域免疫球蛋白及其用途
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AU2009256246B2 (en) 2008-06-03 2013-07-18 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
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TW201109438A (en) * 2009-07-29 2011-03-16 Abbott Lab Dual variable domain immunoglobulins and uses thereof
TW201119673A (en) * 2009-09-01 2011-06-16 Abbott Lab Dual variable domain immunoglobulins and uses thereof
UY32948A (es) * 2009-10-15 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
UY32979A (es) 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
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TW201206473A (en) 2010-08-03 2012-02-16 Abbott Lab Dual variable domain immunoglobulins and uses thereof
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CN106167526A (zh) 2011-07-15 2016-11-30 昂考梅德药品有限公司 Rspo结合剂和其应用
WO2013078223A1 (fr) * 2011-11-23 2013-05-30 Children's Hospital & Research Center Oakland Anticorps anti-protéine liant le facteur h et procédés pour les utiliser
WO2013102042A2 (fr) 2011-12-30 2013-07-04 Abbvie Inc. Protéines à double liaison spécifique dirigées contre l'il-13 et/ou l'il-17
WO2013152252A1 (fr) 2012-04-06 2013-10-10 OSI Pharmaceuticals, LLC Polythérapie antinéoplasique
CA2878868A1 (fr) 2012-07-13 2014-01-16 Austin L. Gurney Agents de liaison des proteines rspo3 et leurs utilisations
HK1212359A1 (en) 2012-11-01 2016-06-10 Abbvie Inc. Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
CN105246915A (zh) * 2013-03-14 2016-01-13 奥尔德生物制药公司 Hgf抗体及含有其的组合物
US9481725B2 (en) 2013-03-14 2016-11-01 Alderbio Holdings, Llc Antibodies to HGF and compositions containing
JP2016522793A (ja) 2013-03-15 2016-08-04 アッヴィ・インコーポレイテッド IL−1βおよび/またはIL−17に対して指向された二重特異的結合タンパク質
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EP3209769B1 (fr) 2014-10-24 2020-08-05 The Board of Trustees of the Leland Stanford Junior University Compositions et procédés pour induire la phagocytose de cellules positives de classe i du cmh et pour contrer la résistance aux agents anti-cd47/sirpa
WO2016065245A1 (fr) 2014-10-24 2016-04-28 Incept, Llc Échafaudage extraluminal
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WO2016205566A1 (fr) * 2015-06-16 2016-12-22 The Regents Of The University Of California Anticorps spécifiques anti-fzd7 et vaccins pour traiter le cancer et réguler la fonction de cellules souches
CA3039910A1 (fr) * 2016-03-28 2017-10-05 The Regents Of The University Of California Anticorps anti-ryk et leurs procedes d'utilisation
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BR112019025583A2 (pt) 2017-06-05 2020-06-16 Janssen Biotech, Inc. Anticorpos multiespecíficos geneticamente modificados e outras proteínas multiméricas com mutações assimétricas na região ch2-ch3
CA3067351A1 (fr) * 2017-06-15 2018-12-20 Nai-Kong Cheung Anticorps anti-l1-cam et leurs utilisations
CN118667812A (zh) 2017-12-06 2024-09-20 艾维迪提生物科学公司 治疗肌萎缩和强直性肌营养不良的组合物和方法
WO2019217450A1 (fr) * 2018-05-08 2019-11-14 Rhode Island Hospital Anticorps anti-chi3l1 pour la détection et/ou le traitement d'une stéatose hépatique non alcoolique / stéatohépatite non alcoolique et des complications subséquentes
JP2022525703A (ja) * 2019-03-20 2022-05-18 ジャベリン・オンコロジー・インコーポレイテッド 抗adam12抗体およびキメラ抗原受容体、ならびにそれを含む組成物および方法
EP4013869A1 (fr) 2019-08-12 2022-06-22 InteRNA Technologies B.V. Nouveaux traitements impliquant le miarn-193a
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Also Published As

Publication number Publication date
US8268315B2 (en) 2012-09-18
ES2378097T3 (es) 2012-04-04
IL195038A0 (en) 2011-08-01
AU2007254853B2 (en) 2011-11-17
US20130203970A1 (en) 2013-08-08
WO2007143098A3 (fr) 2008-06-12
KR20090026315A (ko) 2009-03-12
JP4560582B2 (ja) 2010-10-13
JP5528246B2 (ja) 2014-06-25
AR061170A1 (es) 2008-08-06
EP2029627A2 (fr) 2009-03-04
US20110236377A1 (en) 2011-09-29
JP2009539348A (ja) 2009-11-19
BRPI0712223A2 (pt) 2012-07-10
MX2008015138A (es) 2009-01-28
EP2029627B1 (fr) 2011-11-16
KR101196184B1 (ko) 2012-11-01
JP2010246565A (ja) 2010-11-04
EP2380908A1 (fr) 2011-10-26
US20140178934A1 (en) 2014-06-26
NZ573819A (en) 2011-09-30
WO2007143098A2 (fr) 2007-12-13
IL219655A0 (en) 2012-06-28
US8575318B2 (en) 2013-11-05
CA2654019A1 (fr) 2007-12-13
US20100173361A1 (en) 2010-07-08
WO2007143098A8 (fr) 2009-01-08
AU2007254853A1 (en) 2007-12-13
US7659378B2 (en) 2010-02-09
AU2007254853A2 (en) 2009-02-12
US20080038257A1 (en) 2008-02-14
HK1129394A1 (en) 2009-11-27
ATE533787T1 (de) 2011-12-15
US7935502B2 (en) 2011-05-03

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