[go: up one dir, main page]

NO20084701L - Ny heterocyklisk forbindelse eller salt eller intermediat derav - Google Patents

Ny heterocyklisk forbindelse eller salt eller intermediat derav

Info

Publication number
NO20084701L
NO20084701L NO20084701A NO20084701A NO20084701L NO 20084701 L NO20084701 L NO 20084701L NO 20084701 A NO20084701 A NO 20084701A NO 20084701 A NO20084701 A NO 20084701A NO 20084701 L NO20084701 L NO 20084701L
Authority
NO
Norway
Prior art keywords
salt
substituted
group
heterocyclic compound
new heterocyclic
Prior art date
Application number
NO20084701A
Other languages
English (en)
Inventor
Taro Kiyoto
Junichi Ando
Tadashi Tanaka
Yasuhiro Tsutsui
Mai Yokotani
Toshiya Noguchi
Fumihito Ushiyama
Hiroki Urabe
Hiromasa Horikiri
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of NO20084701L publication Critical patent/NO20084701L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Det er beskrevet en forbindelse som er representert ved den generelle formel: hvor Rrepresenterer en arylgnippe eller heterocyklisk gruppe som kan være substituert, eller lignende; X1 representerer en C2-C4 alkylengruppe eller lignende; X2, X3 og Xrepresenterer uavhengig NH, en binding eller lignende; Xrepresenterer en lavere alkylengruppe, en binding eller lignende; Yrepresenterer en bivalent, alicyklisk hydrokarbonrest som kan være substituert, eller en bivalent alicyklisk aminrest som kan være substituert; og Z,, Z, Zog Zrepresenterer uavhengig et nitrogenatom, en gruppe som er representert ved formelen: CH, eller lignende, forutsatt at minst én av Z, Z, Zog Zrepresenterer et nitrogenatom] eller et salt derav, som er anvendelig som et antibakterielt middel.
NO20084701A 2006-05-26 2008-11-10 Ny heterocyklisk forbindelse eller salt eller intermediat derav NO20084701L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006146588 2006-05-26
PCT/JP2007/060606 WO2007138974A1 (ja) 2006-05-26 2007-05-24 新規な複素環化合物またはその塩ならびにその中間体

Publications (1)

Publication Number Publication Date
NO20084701L true NO20084701L (no) 2009-02-06

Family

ID=38778494

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084701A NO20084701L (no) 2006-05-26 2008-11-10 Ny heterocyklisk forbindelse eller salt eller intermediat derav

Country Status (17)

Country Link
US (2) US8211908B2 (no)
EP (1) EP2022793B1 (no)
JP (1) JP5171618B2 (no)
KR (1) KR101409261B1 (no)
CN (1) CN101454319B (no)
AU (1) AU2007268749B2 (no)
BR (1) BRPI0712163A2 (no)
CA (1) CA2652501C (no)
ES (1) ES2476423T3 (no)
IL (1) IL195346A (no)
MX (1) MX2008014908A (no)
NO (1) NO20084701L (no)
NZ (1) NZ573032A (no)
RU (1) RU2434868C2 (no)
SG (1) SG164384A1 (no)
WO (1) WO2007138974A1 (no)
ZA (1) ZA200809782B (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2006137485A1 (ja) 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. 新規な含窒素複素環化合物およびその塩
WO2007081597A2 (en) * 2005-10-21 2007-07-19 Glaxo Group Limited Peri condensed tricyclic compounds useful as antibacterial agents
KR101409261B1 (ko) 2006-05-26 2014-06-18 다이쇼 세이야꾸 가부시끼가이샤 신규의 복소환 화합물 또는 그 염 및 그 중간체
NZ573644A (en) * 2006-07-20 2011-09-30 Glaxo Group Ltd Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones
EP1992628A1 (en) * 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
WO2008071964A1 (en) * 2006-12-15 2008-06-19 Astrazeneca Ab Naphthyridine bactericides
WO2008071962A1 (en) * 2006-12-15 2008-06-19 Astrazeneca Ab Pteridines and pyrimidinopyridines as antibacterial agents
US20100144717A1 (en) * 2006-12-15 2010-06-10 Janelle Comita-Prevoir 2-quinolinone and 2-quinoxalinone-derivatives and their use as antibacterial agents
TW200831517A (en) * 2006-12-15 2008-08-01 Astrazeneca Ab Chemical compounds
WO2009069589A1 (ja) 2007-11-26 2009-06-04 Toyama Chemical Co., Ltd. 新規なナフチリジン誘導体１水和物およびその製造法
JP5620636B2 (ja) * 2007-11-26 2014-11-05 富山化学工業株式会社 新規な複素環化合物またはその塩を含有する抗菌剤
EP2080761A1 (en) * 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
JP5404652B2 (ja) 2008-02-22 2014-02-05 アクテリオン ファーマシューティカルズ リミテッド オキサゾリジノン誘導体
TWI441830B (zh) * 2008-06-03 2014-06-21 Actelion Pharmaceuticals Ltd 〔４－（１－胺基－乙基）－環己基〕－甲基胺及〔６－（１－胺基－乙基）－四氫－吡喃－３－基〕－甲基－胺衍生物
WO2010027002A1 (ja) * 2008-09-05 2010-03-11 塩野義製薬株式会社 Ｐｉ３ｋ阻害活性を有する縮環モルホリン誘導体
WO2010041218A2 (en) * 2008-10-10 2010-04-15 Actelion Pharmaceuticals Ltd Oxazolidinyl antibiotics
TW201022279A (en) * 2008-11-14 2010-06-16 Astrazeneca Ab Chemical compounds
DK2346819T3 (da) 2008-11-17 2013-05-13 Hoffmann La Roche Naphthyleddikesyre
WO2010081874A1 (en) * 2009-01-15 2010-07-22 Glaxo Group Limited Naphthyridin-2 (1 h)-one compounds useful as antibacterials
EP2391397A2 (en) * 2009-02-02 2011-12-07 Medtronic, Inc. Composite antimicrobial accessory including a membrane layer and a porous layer
AR076222A1 (es) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
US8858983B2 (en) * 2009-04-30 2014-10-14 Medtronic, Inc. Antioxidants and antimicrobial accessories including antioxidants
TW201209056A (en) * 2010-05-25 2012-03-01 Taisho Pharmaceutical Co Ltd Novel heterocyclic compound or salt thereof
US8911427B2 (en) 2010-12-28 2014-12-16 Medtronic, Inc. Therapeutic agent reservoir delivery system
WO2012108376A1 (ja) 2011-02-07 2012-08-16 第一三共株式会社 アミノ基含有ピロリジノン誘導体
US8470884B2 (en) 2011-11-09 2013-06-25 Hoffmann-La Roche Inc. Alkenyl naphthylacetic acids
CA2854266A1 (en) 2011-11-30 2013-06-06 Actelion Pharmaceuticals Ltd 3,7-disubstituted octahydro-2h-pyrido[4,3-e][1,3]oxazin-2-one antibiotics
EP3733184B1 (en) * 2013-03-14 2023-08-30 Icahn School of Medicine at Mount Sinai Pyrimidine compounds for use in the treatment of cancer
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
JP2021505671A (ja) * 2017-12-08 2021-02-18 ザ ロックフェラー ユニバーシティＴｈｅ Ｒｏｃｋｅｆｅｌｌｅｒ Ｕｎｉｖｅｒｓｉｔｙ 中毒症、掻痒症、疼痛および炎症治療用ピラノ［３，４−ｂ］ピラジンカッパオピオイド受容体リガンド
EP3746438A1 (en) * 2018-01-29 2020-12-09 Cadila Healthcare Limited Heterocyclic compounds useful as antibacterial agents
CN109678793B (zh) * 2019-01-12 2020-08-04 上海卡洛化学有限公司 一种5-氟-3-氨基吡啶的制备方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4103257A (en) 1976-05-25 1978-07-25 The United States Of America As Represented By The United States Department Of Energy Azaquinolone dye lasers
US5801183A (en) * 1995-01-27 1998-09-01 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Aza and aza (N-oxy) analogs of glycine/NMDA receptor antagonists
WO1999007682A1 (en) 1997-08-08 1999-02-18 Toyama Chemical Co., Ltd. Quinolonecarboxylic acid derivatives or salts thereof
US6603005B2 (en) 2000-11-15 2003-08-05 Aventis Pharma S.A. Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them
GB0031088D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
US6696565B2 (en) 2001-01-17 2004-02-24 Purdue Research Foundation Method and associated pyrimido[4,5-d]pyrimidine-2,5-diones and pyrido[4,3-d]pyrimidin-2-ones for forming nanotubes
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
AU2002256615B2 (en) * 2001-02-12 2007-09-13 F. Hoffmann-La Roche Ag 6-substituted pyrido-pyrimidines
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
AR040335A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
CN1744899A (zh) * 2002-12-13 2006-03-08 史密丝克莱恩比彻姆公司 作为ccr5拮抗剂的哌啶衍生物
JP4859676B2 (ja) * 2004-02-11 2012-01-25 スミスクライン ビーチャム コーポレーション Ｈｉｖインテグラーゼ阻害剤
EP1773831A1 (en) * 2004-07-08 2007-04-18 Glaxo Group Limited Antibacterial agents
JP2008507543A (ja) 2004-07-22 2008-03-13 グラクソ　グループ　リミテッド 抗細菌剤
ATE484509T1 (de) 2004-08-02 2010-10-15 Glaxo Group Ltd Antibakterielle mittel
JP5314244B2 (ja) * 2004-10-27 2013-10-16 富山化学工業株式会社 新規な含窒素複素環化合物およびその塩
JP2008542249A (ja) * 2005-05-24 2008-11-27 アストラゼネカ アクチボラグ 抗細菌活性を持つアミノピペリジンキノリン及びそのアザ等立体類似体
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2006137485A1 (ja) 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. 新規な含窒素複素環化合物およびその塩
KR101409261B1 (ko) 2006-05-26 2014-06-18 다이쇼 세이야꾸 가부시끼가이샤 신규의 복소환 화합물 또는 그 염 및 그 중간체
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
WO2008071962A1 (en) 2006-12-15 2008-06-19 Astrazeneca Ab Pteridines and pyrimidinopyridines as antibacterial agents
WO2008071964A1 (en) 2006-12-15 2008-06-19 Astrazeneca Ab Naphthyridine bactericides
WO2009001126A1 (en) 2007-06-27 2008-12-31 Astrazeneca Ab Substituted piperidine derivatives and their use as antibaterial agents
WO2009069589A1 (ja) 2007-11-26 2009-06-04 Toyama Chemical Co., Ltd. 新規なナフチリジン誘導体１水和物およびその製造法

Also Published As

Publication number Publication date
IL195346A0 (en) 2009-08-03
MX2008014908A (es) 2009-05-13
CN101454319A (zh) 2009-06-10
SG164384A1 (en) 2010-09-29
WO2007138974A1 (ja) 2007-12-06
IL195346A (en) 2013-02-28
JPWO2007138974A1 (ja) 2009-10-08
EP2022793B1 (en) 2014-06-04
CA2652501C (en) 2014-07-08
RU2434868C2 (ru) 2011-11-27
AU2007268749B2 (en) 2012-07-26
BRPI0712163A2 (pt) 2012-03-13
NZ573032A (en) 2010-12-24
US8211908B2 (en) 2012-07-03
EP2022793A4 (en) 2010-09-08
ES2476423T3 (es) 2014-07-14
AU2007268749A1 (en) 2007-12-06
US20090198063A1 (en) 2009-08-06
ZA200809782B (en) 2010-02-24
RU2008151754A (ru) 2010-07-10
CA2652501A1 (en) 2007-12-06
KR101409261B1 (ko) 2014-06-18
EP2022793A1 (en) 2009-02-11
KR20090018976A (ko) 2009-02-24
US20120226035A1 (en) 2012-09-06
JP5171618B2 (ja) 2013-03-27
US8367831B2 (en) 2013-02-05
HK1133874A1 (en) 2010-04-09
CN101454319B (zh) 2012-06-27

Similar Documents

Publication Publication Date Title
NO20084701L (no) Ny heterocyklisk forbindelse eller salt eller intermediat derav
WO2007016392A3 (en) Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors
WO2008108380A3 (en) Pyrrole compounds
WO2009016841A1 (ja) オキソピラジン誘導体及び除草剤
WO2011004162A3 (en) 1, 2, 4-thiazolidin-3-one derivatives and their use in the treatment of cancer
EA201170632A1 (ru) Цефалоспорины, содержащие катехольную группу
EA200970171A1 (ru) Производные n-(аминогетероарил)-1н-индол-2-карбоксамидов, их получение и их применение в терапии
WO2012080284A3 (en) Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof
EA200800321A1 (ru) Ингибиторы гистондеацетилазы
TW200633991A (en) Chemical compounds
NO20065178L (no) Tienopyridinderivater
MY153720A (en) Oxazole compound and pharmaceutical composition
MY141255A (en) Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
CY1111706T1 (el) Παραγωγα αρυλο- και ετεροαρυλο-πιπεριδινοκαρβοξυλικων αλατων, η παρασκευη τους και η εφαρμογη τους ως αναστολεις του ενζυμου faah
WO2009057811A3 (en) Heterocyclic compound and pharmaceutical composition thereof
UA105185C2 (uk) Піроли
TW200745028A (en) Novel sulphonylpyrroles
NO20076145L (no) Ureadeviater, fremgangsmater for deres fremstilling og anvendelse derav
TW200740752A (en) 4-Biarylyl-1-phenylazetidin-2-ones
GB0521508D0 (en) Organic compounds
MY161134A (en) Piperazine compound having a pgds inhibitory effect
MX2011007864A (es) Isosteros para realzar la transcripcion y su uso en terapia.
TW200745027A (en) Novel sulphonylpyrroles
IN2012DN00758A (no)
MXPA05013584A (es) Compuesto amina terciaria ciclica.