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NO20082748L - Aryl-isoksazol-4-yl-imidazo[1, 5-a]pyridinderivater - Google Patents

Aryl-isoksazol-4-yl-imidazo[1, 5-a]pyridinderivater

Info

Publication number
NO20082748L
NO20082748L NO20082748A NO20082748A NO20082748L NO 20082748 L NO20082748 L NO 20082748L NO 20082748 A NO20082748 A NO 20082748A NO 20082748 A NO20082748 A NO 20082748A NO 20082748 L NO20082748 L NO 20082748L
Authority
NO
Norway
Prior art keywords
lower alkyl
hydrogen
aryl
isoxazol
imidazo
Prior art date
Application number
NO20082748A
Other languages
English (en)
Norwegian (no)
Inventor
Bernd Buettelmann
Bo Han
Henner Knust
Andrew Thomas
Jiaqiang Dong
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20082748L publication Critical patent/NO20082748L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20082748A 2005-12-27 2008-06-13 Aryl-isoksazol-4-yl-imidazo[1, 5-a]pyridinderivater NO20082748L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05112988 2005-12-27
PCT/EP2006/069792 WO2007074089A1 (fr) 2005-12-27 2006-12-18 Derives aryl-isoxazol-4-yl-imidazo[1, 5-a]pyridine

Publications (1)

Publication Number Publication Date
NO20082748L true NO20082748L (no) 2008-09-24

Family

ID=37909303

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082748A NO20082748L (no) 2005-12-27 2008-06-13 Aryl-isoksazol-4-yl-imidazo[1, 5-a]pyridinderivater

Country Status (17)

Country Link
US (1) US7399769B2 (fr)
EP (1) EP1968977B1 (fr)
JP (1) JP4864982B2 (fr)
KR (1) KR101033719B1 (fr)
CN (1) CN101346377B (fr)
AR (1) AR058728A1 (fr)
AT (1) ATE537171T1 (fr)
AU (1) AU2006331363B2 (fr)
BR (1) BRPI0620760A2 (fr)
CA (1) CA2633536A1 (fr)
ES (1) ES2376357T3 (fr)
IL (1) IL192236A0 (fr)
NO (1) NO20082748L (fr)
RU (1) RU2420527C2 (fr)
TW (1) TWI324156B (fr)
WO (1) WO2007074089A1 (fr)
ZA (1) ZA200805354B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1968973E (pt) * 2005-12-27 2011-12-09 Hoffmann La Roche Derivados de aril-isoxazol-4-il-imidazol
ES2369805T3 (es) * 2007-06-22 2011-12-07 F. Hoffmann-La Roche Ag Derivados de isoxazol-imidazol.
KR20120102117A (ko) 2007-12-04 2012-09-17 에프. 호프만-라 로슈 아게 아이속사졸로-피리딘 유도체
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
JP6223443B2 (ja) 2012-06-26 2017-11-01 サニオナ・エイピイエス フェニルトリアゾール誘導体及びｇａｂａａ受容体複合体を調節するための該フェニルトリアゾール誘導体の使用
WO2014001278A1 (fr) 2012-06-26 2014-01-03 Aniona Aps Dérivé de phényle triazole et son utilisation pour moduler le complexe du récepteur gabaa
WO2014001279A1 (fr) 2012-06-26 2014-01-03 Aniona Aps Dérivé de phényle triazole et son utilisation pour moduler le complexe du récepteur gabaa
WO2014001280A1 (fr) 2012-06-26 2014-01-03 Aniona Aps Dérivé de phényle triazole et son utilisation pour moduler le complexe du récepteur gabaa
JP6224097B2 (ja) 2012-06-26 2017-11-01 サニオナ・エイピイエス フェニルトリアゾール誘導体及びｇａｂａａ受受容体複合体を調節するための該フェニルトリアゾール誘導体の使用
PT3105218T (pt) 2014-02-13 2019-12-05 Incyte Corp Ciclopropilaminas como inibidores de lsd1
US9527835B2 (en) 2014-02-13 2016-12-27 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
DK3105226T3 (da) 2014-02-13 2019-10-14 Incyte Corp Cyclopropylaminer som lsd1-inhibitorer
TW201613925A (en) 2014-07-10 2016-04-16 Incyte Corp Imidazopyrazines as LSD1 inhibitors
WO2016007722A1 (fr) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines et triazolopyrazines utilisables comme inhibiteurs de lsd1
TWI687419B (zh) 2014-07-10 2020-03-11 美商英塞特公司 作為ｌｓｄ１抑制劑之咪唑并吡啶及咪唑并吡嗪
EP3626720A1 (fr) 2015-04-03 2020-03-25 Incyte Corporation Composés hétérocycliques utilisés en tant qu'inhibiteurs de lsd1
KR102710120B1 (ko) 2015-08-12 2024-09-27 인사이트 홀딩스 코포레이션 Lsd1 저해제의 염
BR102019014802A2 (pt) 2018-07-20 2020-02-04 Boehringer Ingelheim Int difluorometil-fenil triazóis
US10968200B2 (en) 2018-08-31 2021-04-06 Incyte Corporation Salts of an LSD1 inhibitor and processes for preparing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1257169C (zh) * 1999-10-08 2006-05-24 格吕伦塔尔有限公司 双环咪唑－3－基－胺衍生物
IL149550A0 (en) * 1999-11-12 2002-11-10 Neurogen Corp Bicyclic and tricyclic heteroaromatic compounds
DE60225174T2 (de) * 2001-11-20 2009-02-12 Eli Lilly And Co., Indianapolis Beta-3 adrenergische agonisten

Also Published As

Publication number Publication date
EP1968977A1 (fr) 2008-09-17
KR20080072072A (ko) 2008-08-05
RU2008125040A (ru) 2010-02-10
CN101346377A (zh) 2009-01-14
AR058728A1 (es) 2008-02-20
ATE537171T1 (de) 2011-12-15
TW200734328A (en) 2007-09-16
AU2006331363A1 (en) 2007-07-05
IL192236A0 (en) 2008-12-29
KR101033719B1 (ko) 2011-05-09
AU2006331363B2 (en) 2012-07-05
RU2420527C2 (ru) 2011-06-10
CN101346377B (zh) 2011-05-11
JP4864982B2 (ja) 2012-02-01
ZA200805354B (en) 2009-10-28
ES2376357T3 (es) 2012-03-13
EP1968977B1 (fr) 2011-12-14
TWI324156B (en) 2010-05-01
CA2633536A1 (fr) 2007-07-05
US7399769B2 (en) 2008-07-15
BRPI0620760A2 (pt) 2011-11-22
US20070191421A1 (en) 2007-08-16
JP2009521517A (ja) 2009-06-04
WO2007074089A1 (fr) 2007-07-05

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Legal Events

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