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NO20081374L - Analyser og fremgangsmater som benytter biomarkorer - Google Patents

Analyser og fremgangsmater som benytter biomarkorer

Info

Publication number
NO20081374L
NO20081374L NO20081374A NO20081374A NO20081374L NO 20081374 L NO20081374 L NO 20081374L NO 20081374 A NO20081374 A NO 20081374A NO 20081374 A NO20081374 A NO 20081374A NO 20081374 L NO20081374 L NO 20081374L
Authority
NO
Norway
Prior art keywords
methods
galnac
biomarkers
analyzes
cell sample
Prior art date
Application number
NO20081374A
Other languages
English (en)
Inventor
Avi J Ashkenazi
Klaus W Wagner
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NO20081374L publication Critical patent/NO20081374L/no

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Abstract

Fremgangsmåter og analyser er fremskaffet for undersøkelse av ekspresjon av én eller flere biomarkører i pattedyrvevs- eller -celleprøve. Ifølge de beskrevne fremgangsmåter og analyser er deteksjon av uttrykk av GalNac-T-relaterte molekyler, slik som GalNac-T14 eller GalNac-T3, prediktive eller indikative for at vevs- eller celleprøven vil være sensitiv for apoptoseinduserende midler slik som Apo2L/TRAIL- og anti-DR5-agonistantistoffer. Testsett og fremstilte gjenstander er også fremskaffet.
NO20081374A 2005-08-16 2008-03-14 Analyser og fremgangsmater som benytter biomarkorer NO20081374L (no)

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PCT/US2006/031785 WO2007022157A2 (en) 2005-08-16 2006-08-15 Apoptosis sensitivity to ap02l/trail by testing for 'galnac-t14 expression in cells/tissues

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AU2006279618A1 (en) 2007-02-22
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