NO20076675L - Aminopiperidinquinoliner og deres azaisosteriske analoger med antibakteriell aktivitet - Google Patents
Aminopiperidinquinoliner og deres azaisosteriske analoger med antibakteriell aktivitetInfo
- Publication number
- NO20076675L NO20076675L NO20076675A NO20076675A NO20076675L NO 20076675 L NO20076675 L NO 20076675L NO 20076675 A NO20076675 A NO 20076675A NO 20076675 A NO20076675 A NO 20076675A NO 20076675 L NO20076675 L NO 20076675L
- Authority
- NO
- Norway
- Prior art keywords
- antibacterial activity
- medicaments
- humans
- warm
- bacterial infections
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- RUAZBTOBQDHQDX-UHFFFAOYSA-N piperidin-1-amine;quinoline Chemical class NN1CCCCC1.N1=CC=CC2=CC=CC=C21 RUAZBTOBQDHQDX-UHFFFAOYSA-N 0.000 title 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 3
- 241000282412 Homo Species 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 3
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68403005P | 2005-05-24 | 2005-05-24 | |
| PCT/GB2006/001889 WO2006125974A1 (fr) | 2005-05-24 | 2006-05-23 | Quinoleines d’aminopiperidine et leurs analogues azaisosteriques presentant une activite antibacterienne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076675L true NO20076675L (no) | 2007-12-27 |
Family
ID=36685663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076675A NO20076675L (no) | 2005-05-24 | 2007-12-27 | Aminopiperidinquinoliner og deres azaisosteriske analoger med antibakteriell aktivitet |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20090131444A1 (fr) |
| EP (1) | EP1891078A1 (fr) |
| JP (1) | JP2008542249A (fr) |
| KR (1) | KR20080016577A (fr) |
| CN (1) | CN101258157A (fr) |
| AU (1) | AU2006250987A1 (fr) |
| BR (1) | BRPI0609887A2 (fr) |
| CA (1) | CA2608072A1 (fr) |
| IL (1) | IL187134A0 (fr) |
| MX (1) | MX2007014507A (fr) |
| NO (1) | NO20076675L (fr) |
| RU (1) | RU2007147413A (fr) |
| WO (1) | WO2006125974A1 (fr) |
| ZA (1) | ZA200709870B (fr) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| CN101400674A (zh) * | 2006-03-10 | 2009-04-01 | 埃科特莱茵药品有限公司 | 抗生素化合物 |
| EP2001887B1 (fr) | 2006-04-06 | 2010-09-15 | Glaxo Group Limited | Derives de pyrrolo-quinoxalinone en tant qu'agents antibacteriens |
| SG164384A1 (en) | 2006-05-26 | 2010-09-29 | Toyama Chemical Co Ltd | Novel heterocyclic compound or salt thereof and intermediate thereof |
| TW200815425A (en) * | 2006-06-08 | 2008-04-01 | Speedel Experimenta Ag | 2,5-disubstituted piperidines |
| CA2684659C (fr) * | 2007-04-20 | 2015-11-24 | Glaxo Group Limited | Composes contenant de l'azote tricyclique utilises en tant qu'agents antibacteriens |
| JP5274553B2 (ja) * | 2007-06-15 | 2013-08-28 | アクテリオン ファーマシューティカルズ リミテッド | ３−アミノ−６−（１−アミノ−エチル）−テトラヒドロピラン誘導体 |
| MX2010008922A (es) | 2008-02-20 | 2010-09-07 | Actelion Pharmaceuticals Ltd | Compuestos antibioticos azatriciclicos. |
| MY158520A (en) | 2008-10-07 | 2016-10-14 | Actelion Pharmaceuticals Ltd | Tricyclic oxazolidinone antibiotic compounds |
| WO2010043714A1 (fr) | 2008-10-17 | 2010-04-22 | Glaxo Group Limited | Composés azotés tricycliques utilisés comme agents antibactériens |
| KR101297450B1 (ko) * | 2008-12-12 | 2013-08-20 | 액테리온 파마슈티칼 리미티드 | 5-아미노-2-(1-하이드록시-에틸)-테트라하이드로피란 유도체 |
| WO2010126820A2 (fr) * | 2009-04-30 | 2010-11-04 | Merck Sharp & Dohme Corp. | Préparation d'esters alkyliques d'acides oxo-azacycloalkylcarboxyliques n-protégés |
| PH12012501846A1 (en) * | 2010-04-02 | 2013-02-04 | Firmenich Incorporated | Sweet flavor modifier |
| CA2780403C (fr) * | 2011-06-17 | 2020-04-21 | Forest Laboratories Holdings Ltd. | Procedes de preparation de composes heterocycliques, y compris le trans-7-oxo-6-(sulfoxy)-1,6-diazabicyclo¬3,2,1|octane-2-carboxamide et ses sels |
| RU2617700C2 (ru) | 2011-08-12 | 2017-04-26 | Синомикс, Инк. | Производные 4-аминохинолин-3-карбоновой кислоты и содержащие их композиции для усиления сладкого вкуса |
| WO2013149121A1 (fr) | 2012-03-30 | 2013-10-03 | Cubist Pharmaceuticals, Inc. | Inhibiteurs de la 1,3,4-oxadiazole et de la 1,3,4-thiadiazole bêta-lactamase |
| AR090844A1 (es) * | 2012-04-27 | 2014-12-10 | Actelion Pharmaceuticals Ltd | Proceso para elaborar derivados de naftiridina |
| EP2970338A1 (fr) | 2013-03-14 | 2016-01-20 | Merck Sharp & Dohme Corp. | Forme cristalline d'un inhibiteur de bêta-lactamase |
| WO2015051101A1 (fr) | 2013-10-02 | 2015-04-09 | Cubist Pharmaceuticals, Inc. | Sel picoline inhibiteur de b-lactamase |
| CN103613530B (zh) * | 2013-12-02 | 2015-08-19 | 江苏弘和药物研发有限公司 | 一种芴甲氧羰基-3-哌啶醇的合成方法 |
| ES2762581T3 (es) | 2013-12-27 | 2020-05-25 | Api Corp | Método para producir ácido 5-hidroxipiperidina-2-carboxílico |
| WO2016027249A1 (fr) | 2014-08-22 | 2016-02-25 | Glaxosmithkline Intellectual Property Development Limited | Composés contenant de l'azote tricyclique pour le traitement de l'infection à neisseria gonorrhoeae |
| BR112017008738B1 (pt) | 2014-11-07 | 2021-06-15 | Firmenich Incorporated | Ácidos 4-amino-5-(ciclohexilóxi)quinolina-3-carboxílicos substituídos como modificadores de sabores adoçantes |
| TW201722965A (zh) * | 2015-08-16 | 2017-07-01 | 葛蘭素史密斯克藍智慧財產發展有限公司 | 用於抗菌應用之化合物 |
| AU2017276627A1 (en) * | 2016-06-08 | 2018-12-20 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | New antibacterial compounds |
| CN110036004A (zh) | 2016-07-13 | 2019-07-19 | 希洛斯医药品股份有限公司 | 细胞周期蛋白依赖性激酶7(cdk7)的抑制剂 |
| ES2984497T3 (es) | 2017-06-30 | 2024-10-29 | Elanco Animal Health Gmbh | Nuevos derivados de azaquinolina |
| IL301709B2 (en) | 2017-08-09 | 2025-07-01 | Denali Therapeutics Inc | Compounds, compositions and methods |
| EP3676297B1 (fr) * | 2017-09-01 | 2023-05-17 | Denali Therapeutics Inc. | Composés, compositions et procédés |
| JP7158393B2 (ja) | 2017-09-14 | 2022-10-21 | 第一三共株式会社 | 環状構造を有する化合物 |
| MX2021005007A (es) | 2018-11-01 | 2021-07-21 | Syros Pharmaceuticals Inc | Inhibidores de cinasa 7 dependiente de ciclina (cdk7). |
| EP3924341A4 (fr) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | Composés, compositions et procédés |
| BR112021015639A2 (pt) | 2019-02-13 | 2021-10-05 | Denali Therapeutics Inc. | Compostos, composições e métodos |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9822450D0 (en) * | 1998-10-14 | 1998-12-09 | Smithkline Beecham Plc | Medicaments |
| DE60125373T2 (de) * | 2000-07-26 | 2007-10-18 | Smithkline Beecham P.L.C., Brentford | Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung |
| EP1719770A3 (fr) * | 2000-09-21 | 2008-03-05 | Smithkline Beecham Plc | Dérivés de quinoline comme agents antibactériens |
| JP4887297B2 (ja) * | 2004-09-24 | 2012-02-29 | アクテリオン ファーマシューティカルズ リミテッド | 新規二環式抗生物質 |
-
2006
- 2006-05-23 AU AU2006250987A patent/AU2006250987A1/en not_active Abandoned
- 2006-05-23 EP EP06743966A patent/EP1891078A1/fr not_active Withdrawn
- 2006-05-23 CA CA002608072A patent/CA2608072A1/fr not_active Abandoned
- 2006-05-23 JP JP2008512908A patent/JP2008542249A/ja active Pending
- 2006-05-23 RU RU2007147413/04A patent/RU2007147413A/ru not_active Application Discontinuation
- 2006-05-23 WO PCT/GB2006/001889 patent/WO2006125974A1/fr not_active Ceased
- 2006-05-23 BR BRPI0609887-8A patent/BRPI0609887A2/pt not_active Application Discontinuation
- 2006-05-23 US US11/914,799 patent/US20090131444A1/en not_active Abandoned
- 2006-05-23 CN CNA2006800266719A patent/CN101258157A/zh active Pending
- 2006-05-23 MX MX2007014507A patent/MX2007014507A/es not_active Application Discontinuation
- 2006-05-23 KR KR1020077027342A patent/KR20080016577A/ko not_active Withdrawn
-
2007
- 2007-11-04 IL IL187134A patent/IL187134A0/en unknown
- 2007-11-15 ZA ZA200709870A patent/ZA200709870B/xx unknown
- 2007-12-27 NO NO20076675A patent/NO20076675L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008542249A (ja) | 2008-11-27 |
| KR20080016577A (ko) | 2008-02-21 |
| AU2006250987A1 (en) | 2006-11-30 |
| US20090131444A1 (en) | 2009-05-21 |
| BRPI0609887A2 (pt) | 2011-10-11 |
| IL187134A0 (en) | 2008-02-09 |
| MX2007014507A (es) | 2008-02-07 |
| ZA200709870B (en) | 2008-11-26 |
| CN101258157A (zh) | 2008-09-03 |
| CA2608072A1 (fr) | 2006-11-30 |
| RU2007147413A (ru) | 2009-06-27 |
| EP1891078A1 (fr) | 2008-02-27 |
| WO2006125974A1 (fr) | 2006-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |