NO20076467L - Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteiner - Google Patents
Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteinerInfo
- Publication number
- NO20076467L NO20076467L NO20076467A NO20076467A NO20076467L NO 20076467 L NO20076467 L NO 20076467L NO 20076467 A NO20076467 A NO 20076467A NO 20076467 A NO20076467 A NO 20076467A NO 20076467 L NO20076467 L NO 20076467L
- Authority
- NO
- Norway
- Prior art keywords
- hiv
- derivative
- tat
- proteins
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Oppfinnelsen tilveiebringer (a) et HIV-Tat-protein eller derivat derav koblet til enten (i) en fusjonspartner eller (ii) et HTV Nef-protein eller derivat derav; eller (b) et HTV Nef-protein eller derivat derav koblet til enten (i) en fusjonspartner eller (ii) et HIV-Tat-protein eller derivat derav; eller (c) et HTV-Nef-protein eller derivat derav koblet til et HIV-Tat-protein eller derivat derav og en fusjonspartner. Oppfinnelsen tilveiebringer videre en nukleinsyre som koder for et slikt protein og en vertscelle, slik som Pichia Pastoris, transformert med den før nevnte nukleinsyren.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9720585.0A GB9720585D0 (en) | 1997-09-26 | 1997-09-26 | Vaccine |
| PCT/EP1998/006040 WO1999016884A1 (en) | 1997-09-26 | 1998-09-17 | Fusion proteins comprising hiv-1 tat and/or nef proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076467L true NO20076467L (no) | 2000-05-18 |
Family
ID=10819735
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20001508A NO328824B1 (no) | 1997-09-26 | 2000-03-23 | Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. |
| NO20076467A NO20076467L (no) | 1997-09-26 | 2007-12-14 | Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteiner |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20001508A NO328824B1 (no) | 1997-09-26 | 2000-03-23 | Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1015596B2 (no) |
| JP (2) | JP2001518300A (no) |
| KR (1) | KR100554487B1 (no) |
| CN (1) | CN1188519C (no) |
| AR (2) | AR017147A1 (no) |
| AT (1) | ATE338128T1 (no) |
| AU (1) | AU746564B2 (no) |
| BR (1) | BR9812547A (no) |
| CA (1) | CA2305013C (no) |
| CO (1) | CO4810339A1 (no) |
| CZ (1) | CZ302878B6 (no) |
| DE (1) | DE69835756T3 (no) |
| DK (1) | DK1015596T4 (no) |
| ES (1) | ES2272012T5 (no) |
| GB (1) | GB9720585D0 (no) |
| HU (1) | HUP0004896A3 (no) |
| IL (1) | IL135102A0 (no) |
| NO (2) | NO328824B1 (no) |
| NZ (1) | NZ503482A (no) |
| PL (1) | PL195243B1 (no) |
| PT (1) | PT1015596E (no) |
| SA (1) | SA98190877B1 (no) |
| SI (1) | SI1015596T2 (no) |
| TR (1) | TR200000864T2 (no) |
| TW (1) | TW499436B (no) |
| WO (1) | WO1999016884A1 (no) |
| ZA (1) | ZA988789B (no) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| GB9720585D0 (en) * | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
| GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| CA2363118A1 (en) * | 1999-02-25 | 2000-08-31 | Smithkline Beecham Biologicals S.A. | Immunogens comprising a peptide and a carrier derived from h.influenzae protein d |
| CA2369884C (en) * | 1999-04-12 | 2010-01-05 | Modex Therapeutiques, S.A. | Transiently immortalized cells for use in gene therapy |
| CA2376992A1 (en) * | 1999-06-29 | 2001-01-04 | Smithkline Beecham Biologicals S.A. | Use of cpg as an adjuvant for hiv vaccine |
| GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| KR20070073987A (ko) * | 2000-01-31 | 2007-07-10 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | Hiv에 대한 예방 또는 치료용 면역화를 위한 백신 |
| US6472176B2 (en) | 2000-12-14 | 2002-10-29 | Genvec, Inc. | Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof |
| GB0110431D0 (en) * | 2001-04-27 | 2001-06-20 | Glaxosmithkline Biolog Sa | Novel compounds |
| EP1279404A1 (en) * | 2001-07-26 | 2003-01-29 | Istituto Superiore di Sanità | Use of HIV-1 tat, fragments or derivatives thereof, to target or to activate antigen-presenting cells, to deliver cargo molecules for vaccination or to treat other diseases |
| GB0118367D0 (en) * | 2001-07-27 | 2001-09-19 | Glaxosmithkline Biolog Sa | Novel use |
| SG2013034475A (en) | 2001-11-21 | 2016-10-28 | Univ Pennsylvania | Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use |
| EP1944043A1 (en) | 2001-11-21 | 2008-07-16 | The Trustees of the University of Pennsylvania | Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use |
| KR100466382B1 (ko) * | 2002-01-08 | 2005-01-14 | 주식회사 엘지생명과학 | 인간 면역 결핍 바이러스-1, -2 타입의 단백질이 융합된 재조합 콤보 단백질, 이의 생산방법, 이를 포함하는 벡터, 형질전환된 대장균 및 진단키트 |
| GB0206359D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| GB0206360D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| CN1982332A (zh) * | 2002-05-16 | 2007-06-20 | 巴法里安诺迪克有限公司 | Hiv调节/辅助蛋白的融合蛋白 |
| GB0225788D0 (en) | 2002-11-05 | 2002-12-11 | Glaxo Group Ltd | Vaccine |
| WO2005090968A1 (en) | 2004-03-16 | 2005-09-29 | Inist Inc. | Tat-based immunomodulatory compositions and methods of their discovery and use |
| TW200613554A (en) | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
| GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| GB0507003D0 (en) * | 2005-04-06 | 2005-05-11 | Molmed Spa | Therapeutic |
| CN105483088B (zh) | 2005-10-18 | 2021-05-28 | 国家犹太健康中心 | 条件无限增殖化长期干细胞和制备和使用所述细胞的方法 |
| MX2010005860A (es) | 2007-11-28 | 2010-06-22 | Univ Pennsylvania | Adenovirus simianos de la subfamilia c sadv-40, sadv-31 y sadv-34 y usos de los mismos. |
| SI2220241T1 (sl) | 2007-11-28 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Adenovirus, ki obsega kapsidni heksonski protein opičjega E adenovirusa SAdV-39, in njegove uporabe |
| JP5661476B2 (ja) | 2008-03-04 | 2015-01-28 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | サルアデノウイルスSAdV−36、−42.1、−42.2および−44ならびにそれらの用途 |
| ES2820873T3 (es) | 2008-05-16 | 2021-04-22 | Taiga Biotechnologies Inc | Anticuerpos y su procesos de preparación |
| CN103937749B (zh) | 2008-07-21 | 2018-04-17 | 泰加生物工艺学公司 | 分化无核细胞及其制备方法 |
| ES2681478T3 (es) | 2008-08-28 | 2018-09-13 | Taiga Biotechnologies, Inc. | Moduladores de MYC, métodos de uso de los mismos y métodos para identificar agentes que modulan MYC |
| US8940290B2 (en) | 2008-10-31 | 2015-01-27 | The Trustees Of The University Of Pennsylvania | Simian adenoviruses SAdV-43, -45, -46, -47, -48, -49, and -50 and uses thereof |
| DK2411043T3 (da) | 2009-03-23 | 2013-10-21 | Pin Pharma Inc | Behandling af cancer med immunostimulatorisk hiv tat derivat-polypeptider |
| CA2762203A1 (en) | 2009-05-29 | 2010-12-02 | Soumitra Roy | Simian adenovirus 41 and uses thereof |
| EP3075860A1 (en) | 2010-11-23 | 2016-10-05 | The Trustees of the University of Pennsylvania | Subfamily e simian adenovirus a1295 and uses thereof |
| US9110059B2 (en) * | 2011-03-15 | 2015-08-18 | Industry-Academic Cooperation Foundation, Yonsei University | Bio-pin |
| MX358019B (es) | 2012-05-18 | 2018-08-02 | Univ Pennsylvania | Adenovirus de simio de la subfamilia e a1302, a1320, a1331 y a1337 y sus usos. |
| WO2014012090A1 (en) | 2012-07-13 | 2014-01-16 | The Broad Institute, Inc. | Molecular sleds comprising a positively-charged amino acid sequence and a molecular cargo and uses thereof |
| CA3133302A1 (en) | 2012-07-20 | 2014-01-23 | Taiga Biotechnologies, Inc. | Enhanced reconstitution and autoreconstitution of the hematopoietic compartment comprising a myc polypeptide |
| US9365825B2 (en) | 2013-03-11 | 2016-06-14 | Taiga Biotechnologies, Inc. | Expansion of adult stem cells in vitro |
| US10272115B2 (en) | 2013-03-11 | 2019-04-30 | Taiga Biotechnologies, Inc. | Production and use of red blood cells |
| AU2014329393B2 (en) | 2013-10-04 | 2020-04-30 | Pin Pharma, Inc. | Immunostimulatory HIV Tat derivative polypeptides for use in cancer treatment |
| PT3142750T (pt) | 2014-05-13 | 2020-09-22 | Univ Pennsylvania | Composições que compreendem aav expressando construções de anticorpos duplos e suas utilizações |
| ES2865392T7 (es) * | 2015-04-16 | 2022-09-07 | The Research Foundation For The State Univ Of New York Univ At Buffalo | Nanoestructuras que comprenden conjugados de porfirina de cobalto-fosfolípido y etiquetas de polihistidina |
| US11207421B2 (en) | 2015-04-16 | 2021-12-28 | The Research Foundation For The State University Of New York | Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags |
| AU2017367730A1 (en) | 2016-12-02 | 2019-06-06 | Taiga Biotechnologies, Inc. | Nanoparticle formulations |
| US10149898B2 (en) | 2017-08-03 | 2018-12-11 | Taiga Biotechnologies, Inc. | Methods and compositions for the treatment of melanoma |
| AU2020272664A1 (en) | 2019-04-08 | 2021-11-04 | Taiga Biotechnologies, Inc. | Compositions and methods for the cry opreservation of immune cells |
| AU2020274117A1 (en) | 2019-05-14 | 2021-12-02 | Taiga Biotechnologies, Inc. | Compositions and methods for treating T cell exhaustion |
| MX2023012643A (es) | 2021-04-27 | 2024-01-05 | Generation Bio Co | Vectores de adn no virales que expresan anticuerpos terapéuticos y usos de estos. |
| KR20240161965A (ko) | 2022-03-14 | 2024-11-13 | 제너레이션 바이오 컴퍼니 | 이종 프라임 부스트 백신 조성물 및 사용 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9003010D0 (en) * | 1990-02-09 | 1990-04-04 | Glaxo Group Ltd | Gene expression in yeast cells |
| CA2121493A1 (en) * | 1991-10-21 | 1993-04-29 | Charles K. Stover | Bacterial expression vectors containing dna encoding secretion signals of lipoproteins |
| ATE173016T1 (de) * | 1992-08-21 | 1998-11-15 | Biogen Inc | Von tat abgeleitete transportpolypeptide |
| DE69434469T2 (de) * | 1993-01-26 | 2006-06-14 | Univ Pennsylvania | Zusammensetzungen und verfahren zur verabreichung von genetischem material |
| JPH11501310A (ja) * | 1995-03-08 | 1999-02-02 | ネオバック | レトロウイルスの調節タンパク質から誘導された無毒の免疫原、抗体、製造方法およびそれらを含んでなる医薬組成物 |
| GB9720585D0 (en) * | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
-
1997
- 1997-09-26 GB GBGB9720585.0A patent/GB9720585D0/en not_active Ceased
-
1998
- 1998-09-17 HU HU0004896A patent/HUP0004896A3/hu unknown
- 1998-09-17 CA CA002305013A patent/CA2305013C/en not_active Expired - Fee Related
- 1998-09-17 ES ES98952625T patent/ES2272012T5/es not_active Expired - Lifetime
- 1998-09-17 BR BR9812547-8A patent/BR9812547A/pt not_active IP Right Cessation
- 1998-09-17 DE DE69835756T patent/DE69835756T3/de not_active Expired - Lifetime
- 1998-09-17 PL PL98339432A patent/PL195243B1/pl not_active IP Right Cessation
- 1998-09-17 NZ NZ503482A patent/NZ503482A/en not_active IP Right Cessation
- 1998-09-17 IL IL13510298A patent/IL135102A0/xx not_active IP Right Cessation
- 1998-09-17 DK DK98952625.6T patent/DK1015596T4/da active
- 1998-09-17 TR TR2000/00864T patent/TR200000864T2/xx unknown
- 1998-09-17 CN CNB988114321A patent/CN1188519C/zh not_active Expired - Fee Related
- 1998-09-17 AT AT98952625T patent/ATE338128T1/de active
- 1998-09-17 SI SI9830860T patent/SI1015596T2/sl unknown
- 1998-09-17 CZ CZ20001091A patent/CZ302878B6/cs not_active IP Right Cessation
- 1998-09-17 JP JP2000513953A patent/JP2001518300A/ja not_active Withdrawn
- 1998-09-17 AU AU10255/99A patent/AU746564B2/en not_active Ceased
- 1998-09-17 KR KR1020007003180A patent/KR100554487B1/ko not_active Expired - Fee Related
- 1998-09-17 EP EP98952625A patent/EP1015596B2/en not_active Expired - Lifetime
- 1998-09-17 PT PT98952625T patent/PT1015596E/pt unknown
- 1998-09-17 WO PCT/EP1998/006040 patent/WO1999016884A1/en not_active Ceased
- 1998-09-24 AR ARP980104779A patent/AR017147A1/es active IP Right Grant
- 1998-09-25 CO CO98056054A patent/CO4810339A1/es unknown
- 1998-09-25 ZA ZA9808789A patent/ZA988789B/xx unknown
- 1998-10-22 TW TW087117493A patent/TW499436B/zh not_active IP Right Cessation
- 1998-12-15 SA SA98190877A patent/SA98190877B1/ar unknown
-
2000
- 2000-03-23 NO NO20001508A patent/NO328824B1/no not_active IP Right Cessation
-
2007
- 2007-12-14 NO NO20076467A patent/NO20076467L/no unknown
-
2009
- 2009-06-30 JP JP2009155916A patent/JP2009213492A/ja active Pending
-
2011
- 2011-02-28 AR ARP110100606A patent/AR080331A2/es not_active Application Discontinuation
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