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NO20075322L - NPY antagonister, samt femstilling og anvendelse av samme - Google Patents

NPY antagonister, samt femstilling og anvendelse av samme

Info

Publication number
NO20075322L
NO20075322L NO20075322A NO20075322A NO20075322L NO 20075322 L NO20075322 L NO 20075322L NO 20075322 A NO20075322 A NO 20075322A NO 20075322 A NO20075322 A NO 20075322A NO 20075322 L NO20075322 L NO 20075322L
Authority
NO
Norway
Prior art keywords
npy
compounds
preparation
antagonists
compound
Prior art date
Application number
NO20075322A
Other languages
English (en)
Inventor
Claudine Serradeil-Legal
Gerard Valette
Iuliana Botez
Christelle David-Basei
Nelly Gourlaouen
Eric Nicolai
Fabrice Balavoine
Original Assignee
Cerep
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerep filed Critical Cerep
Publication of NO20075322L publication Critical patent/NO20075322L/no

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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/452—Piperidinium derivatives
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

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  • Chemical & Material Sciences (AREA)
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Abstract

Det beskrives nye forbindelser, fremstilling og anvendelse av disse, og spesielt terapeutiske anvendelser. Nærmere bestemt vedrører oppfinnelsen forbindelser som har minst to aromatiske ringer, fremstilling og anvendelse av disse, spesielt innenfor området helse for menneske eller dyr. Disse forbindelser har en affinitet for biologiske reseptorer av neuropeptid Y, NPY, som foreligger i det sentrale og perifere nervesystem. Forbindelsene ifølge oppfinnelsen er fortrinnsvis NPY-antagonister, og mer fortrinnsvis antagonister av sub-type NPY Y1, og kan derfor anvendes for terapeutisk eller profylaktisk behandling av enhver forstyrrelse som involverer NPY. Foreliggende oppfinnelse vedrører også farmasøytiske ) sammensetninger inneholdende nevnte forbindelse, fremstilling og anvendelse av disse, og likeledes behandlingsmetoder ved anvendelse av nevnte forbindelse.
NO20075322A 2005-04-15 2007-10-17 NPY antagonister, samt femstilling og anvendelse av samme NO20075322L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0503795A FR2884516B1 (fr) 2005-04-15 2005-04-15 Antagonistes npy, preparation et utilisations
PCT/FR2006/000829 WO2006108965A2 (fr) 2005-04-15 2006-04-14 Antagonistes npy, preparation et utilisations

Publications (1)

Publication Number Publication Date
NO20075322L true NO20075322L (no) 2008-01-11

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ID=35447654

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NO20075322A NO20075322L (no) 2005-04-15 2007-10-17 NPY antagonister, samt femstilling og anvendelse av samme

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Country Link
US (1) US20090233910A1 (no)
EP (1) EP1879887A2 (no)
JP (1) JP2008538749A (no)
KR (1) KR20080009112A (no)
CN (1) CN101198604A (no)
AP (1) AP2007004218A0 (no)
AU (1) AU2006234413A1 (no)
CA (1) CA2604773A1 (no)
CR (1) CR9514A (no)
EA (1) EA200800157A1 (no)
EC (1) ECSP077894A (no)
FR (1) FR2884516B1 (no)
IL (1) IL186601A0 (no)
MA (1) MA29444B1 (no)
MX (1) MX2007012847A (no)
NI (1) NI200700260A (no)
NO (1) NO20075322L (no)
TN (1) TNSN07376A1 (no)
WO (1) WO2006108965A2 (no)

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US20090233910A1 (en) 2009-09-17
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CA2604773A1 (fr) 2006-10-19
ECSP077894A (es) 2008-03-26
WO2006108965A2 (fr) 2006-10-19
MX2007012847A (es) 2008-03-25
NI200700260A (es) 2009-03-03
FR2884516B1 (fr) 2007-06-22
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JP2008538749A (ja) 2008-11-06
EP1879887A2 (fr) 2008-01-23
AU2006234413A1 (en) 2006-10-19
CR9514A (es) 2008-08-26
IL186601A0 (en) 2008-01-20
AP2007004218A0 (en) 2007-10-31
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TNSN07376A1 (en) 2009-03-17
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