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NO20075166L - Dendrittiske celleblandinger og fremgangsmater - Google Patents

Dendrittiske celleblandinger og fremgangsmater

Info

Publication number
NO20075166L
NO20075166L NO20075166A NO20075166A NO20075166L NO 20075166 L NO20075166 L NO 20075166L NO 20075166 A NO20075166 A NO 20075166A NO 20075166 A NO20075166 A NO 20075166A NO 20075166 L NO20075166 L NO 20075166L
Authority
NO
Norway
Prior art keywords
methods
dendritic cells
monocytes
dendritic cell
cell mixtures
Prior art date
Application number
NO20075166A
Other languages
English (en)
Other versions
NO345353B1 (no
Inventor
Rebecca Pogue-Caley
Tamara Monesmith
Irina Tcherepanova
Lois Dinterman
Original Assignee
Kirin Pharma Kk
Argos Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Pharma Kk, Argos Therapeutics Inc filed Critical Kirin Pharma Kk
Publication of NO20075166L publication Critical patent/NO20075166L/no
Publication of NO345353B1 publication Critical patent/NO345353B1/no

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/19Dendritic cells
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    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract

Fremgangsmåter tilveiebringes for fremstilling av dendrittiske celler fra monocytter som har blitt inkubert ved en temperatur på 1°C - 34 °C i et tidsrom på omtrent 6 til 96 timer fra det tidspunktet de blir isolert fra et subjekt. Etter inkuberingsperioden kan monocyttene deretter induseres til å differensiere til dendrittiske celler. Modne dendrittiske celler fremstilt ved fremgangsmåtene ifølge oppfinnelsen har økte nivåer av én eller flere av CD80, CD83, CD86, MHC klasse I-molekyler eller MHC klasse II-molekyler sammenlignet med modne dendrittiske celler fremstilt fra monocytter som ikke har blitt holdt ved 1°C-34 °C i minst 6 timer fra det tidspunktet de ble isolert fra et subjekt. Dendrittiske celler fremstilt ved fremgangsmåtene ifølge oppfinnelsen er anvendelige for fremstilling av vaksiner og for stimulering av T-celler. 1
NO20075166A 2005-04-08 2007-10-10 Dendrittiske celleblandinger og fremgangsmåter NO345353B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66946805P 2005-04-08 2005-04-08
PCT/US2006/013159 WO2006127150A2 (en) 2005-04-08 2006-04-07 Dendritic cell compositions and methods

Publications (2)

Publication Number Publication Date
NO20075166L true NO20075166L (no) 2007-12-27
NO345353B1 NO345353B1 (no) 2020-12-21

Family

ID=36992670

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075166A NO345353B1 (no) 2005-04-08 2007-10-10 Dendrittiske celleblandinger og fremgangsmåter

Country Status (12)

Country Link
US (6) USRE46152E1 (no)
EP (1) EP1882031B1 (no)
JP (1) JP5020935B2 (no)
KR (6) KR20200072566A (no)
CN (1) CN101155914B (no)
AU (1) AU2006249640C1 (no)
CA (1) CA2602434C (no)
ES (1) ES2650569T3 (no)
IL (2) IL185977A0 (no)
MX (1) MX2007012221A (no)
NO (1) NO345353B1 (no)
WO (1) WO2006127150A2 (no)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8513008B2 (en) * 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
MY145814A (en) * 2005-12-08 2012-04-30 Dandrit Biotech As Method for generating dendritic cells employing decreased temperature
KR102230288B1 (ko) 2006-04-14 2021-03-22 아스텔라스 인스티튜트 포 리제너러티브 메디슨 혈관 콜로니 형성 세포
US8877206B2 (en) 2007-03-22 2014-11-04 Pds Biotechnology Corporation Stimulation of an immune response by cationic lipids
US8524495B2 (en) 2007-05-16 2013-09-03 Yale University Methods for inducing the differentiation of blood monocytes into functional dendritic cells
KR100935826B1 (ko) 2007-11-27 2010-01-08 주식회사 바이넥스 부유밀도구배 원심분리를 이용하여 말초혈액단핵구로부터 단세포를 분리하는 방법
US8513208B2 (en) 2008-02-28 2013-08-20 Argos Therapeutics, Inc. Transient expression of immunomodulatory polypeptides for the prevention and treatment of autoimmune disease, allergy and transplant rejection
AU2009228215B2 (en) * 2008-03-27 2015-12-10 Asterias Biotherapeutics, Inc. Differentiation of primate pluripotent stem cells to hematopoietic lineage cells
ES2712505T3 (es) 2008-04-17 2019-05-13 Pds Biotechnology Corp Estimulación de una respuesta inmunitaria por enantiómeros de lípidos catiónicos
EP2352527A1 (en) * 2008-11-04 2011-08-10 Idera Pharmaceuticals, Inc. Modulation of toll-like receptor 2 expression by antisense oligonucleotides
BR112012005713A2 (pt) * 2009-09-14 2019-09-24 Baylor Res Institute vacinas direcionadas a célula langerhans.
CA3095576A1 (en) * 2009-12-04 2011-06-09 Astellas Institute For Regenerative Medicine Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
EP2547360A4 (en) * 2010-03-15 2013-11-20 Univ Pennsylvania SYSTEM AND METHOD FOR THE PRODUCTION AND STORAGE OF ACTIVATED TIRES OF DENDRITIC CELLS
EP2898890B1 (en) 2010-03-31 2019-08-21 Stabilitech Biopharma Ltd Stabilisation of viral particles
HUE042330T2 (hu) 2010-03-31 2019-06-28 Stabilitech Biopharma Ltd Módszer alumínium adjuvánsok és alumíniummal adjuvált vakcinák megóvására
HUE033656T2 (en) 2010-03-31 2017-12-28 Stabilitech Ltd Binders for stabilizing virus particles
US20130011438A1 (en) * 2011-07-05 2013-01-10 SOTIO a.s. Means And Methods For Active Cellular Immunotherapy Of Cancer By Using Tumor Cells Killed By High Hydrostatic Pressure and Dendritic Cells
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
HRP20181515T1 (hr) 2011-11-30 2018-11-16 Astellas Institute For Regenerative Medicine Mezenhimne stromalne stanice i upotreba povezana s njima
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
WO2013118899A1 (ja) * 2012-02-10 2013-08-15 医療法人社団博心厚生会 単球増殖剤、単球増殖用培地、単球の製造方法、樹状細胞の製造方法、及び樹状細胞ワクチンの製造方法
US9701942B2 (en) 2012-05-31 2017-07-11 Jw Creagene Inc. Composition for maturing dendritic cells, and method for preparing antigen-specific dendritic cells using same
CA2876656C (en) 2012-06-15 2023-09-26 Pds Biotechnology Corporation Cationic lipid vaccine compositions and methods of use
WO2014011407A2 (en) 2012-07-12 2014-01-16 Imstem Biotechnology, Inc. Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
TWI672149B (zh) 2012-09-21 2019-09-21 美商Pds生技公司 改良之疫苗組成物及使用方法
AU2014213009B2 (en) * 2013-02-01 2019-01-03 Kira Biotech Pty Limited Anti-CD83 antibodies and use thereof
ES2894633T3 (es) * 2013-03-15 2022-02-15 Genzyme Corp Métodos de establecimiento bancos de células de alta densidad
CA2940163C (en) * 2014-02-21 2022-05-17 Argos Therapeutics, Inc. Tscm cells and methods for use
CN103948917A (zh) * 2014-04-02 2014-07-30 江苏和泽生物科技有限公司 树突状细胞疫苗的制备方法
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB201413665D0 (en) 2014-07-03 2014-09-17 Transimmune Ag And Yale University Method for obtaining globally activated monocytes
KR101518972B1 (ko) * 2014-08-01 2015-05-18 제이더블유크레아젠 주식회사 수지상세포의 제조방법, 이에 의해 제조된 수지상세포 및 그 용도
JP6531256B2 (ja) * 2014-11-14 2019-06-19 日本赤十字社 臍帯血および末梢血の凍結保存方法および凍結保存用溶液
CA2982606A1 (en) * 2015-05-01 2016-11-10 Baylor College Of Medicine Methods for enhancing an immune response with a ctla-4 antagonist
CA2991212A1 (en) * 2015-07-02 2017-01-05 PrimeVax Immuno-Oncology, Inc. Compositions and methods for combination therapy with dengue virus and dendritic cells
EP3374496A4 (en) * 2015-11-13 2019-07-10 PDS Biotechnology Corporation LIPIDES AS SYNTHETIC VECTORS FOR IMPROVING ANTIGEN PROCESSING AND PRESENTATION EX-VIVO IN DENDRITIC CELL THERAPY
JP6779616B2 (ja) * 2015-12-25 2020-11-04 富士ソフト株式会社 Nkt細胞活性化医薬組成物、その製造方法、及び抗原提示細胞の保存方法
JP7185530B2 (ja) 2016-06-13 2022-12-07 トルク セラピューティクス, インコーポレイテッド 免疫細胞機能を促進するための方法および組成物
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions
CA3074826A1 (en) 2017-09-05 2019-03-14 Torque Therapeutics, Inc. Therapeutic protein compositions and methods of making and using the same
EP3706765A4 (en) * 2017-11-07 2021-07-14 Coimmune, Inc. METHODS AND USES FOR DENDRITIC CELL THERAPY
CN111670040A (zh) * 2018-01-08 2020-09-15 密歇根大学董事会 Aldh1抗原冲击树突状细胞
WO2019196088A1 (en) * 2018-04-13 2019-10-17 Syz Cell Therapy Co. Methods of obtaining tumor-specific t cell receptors
CN112703004B (zh) 2018-07-15 2025-02-14 雷诺瓦罗生物制药公司 使用重组树突状细胞用于癌症治疗的方法和组合物
KR102159766B1 (ko) * 2018-11-12 2020-09-24 조선대학교산학협력단 홍조류추출물을 이용한 미성숙수지상세포 분화유도용 배지조성물 및 미성숙수지상세포 분화유도방법
WO2020188573A1 (en) * 2019-03-21 2020-09-24 Gamida-Cell Ltd. Expanded nk cell fractions for transplantation in combination therapy
CN114621921A (zh) * 2020-12-11 2022-06-14 深圳先进技术研究院 一种提取神经突触体的方法
JP7426165B2 (ja) * 2021-06-30 2024-02-01 ノバセラム株式会社 血中循環腫瘍細胞を含む試料を調製する方法
CN113980901B (zh) * 2021-12-28 2022-06-17 上海惠盾因泰生物科技有限公司 一种制备高纯度的成熟人树突状细胞的方法及应用
WO2023245609A1 (en) * 2022-06-24 2023-12-28 Lihpao Life Science Corp. Method for producing mature dendritic cells
US20240216101A1 (en) * 2023-01-04 2024-07-04 Sheridan O'Neal Carriers for Collecting Biological Samples

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7659119B2 (en) * 1996-02-12 2010-02-09 Argos Therapeutics, Inc. Method and compositions for obtaining mature dendritic cells
US5853719A (en) 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
KR20000022445A (ko) 1996-07-10 2000-04-25 크리스토퍼 엘. 와이트, 스코트 지. 홀퀴스트, 스티븐 엘. 말라스카 수상돌기 세포의 활성화 방법
US20050158856A1 (en) 1999-04-20 2005-07-21 Edelson Richard L. Methods for producing functional antigen presenting dendritic cells using biodegradable microparticles for delivery of antigenic materials
US20050084966A1 (en) * 1999-04-20 2005-04-21 Edelson Richard L. Methods for inducing the differentiation of blood monocytes into functional dendritic cells
WO2000062818A1 (en) 1999-04-20 2000-10-26 Richard Leslie Edelson Differentiation of monocytes into functional dendritic cells
IT1312570B1 (it) * 1999-05-28 2002-04-22 Genera Spa Metodo per il traferimento di antigeni a cellule dendritiche.
DE10041515A1 (de) 2000-08-24 2002-03-14 Gerold Schuler Verfahren zur Herstellung gebrauchsfertiger, Antigen-beladener oder -unbeladener, kryokonservierter reifer dendritischer Zellen
EP1270732A1 (en) 2001-06-21 2003-01-02 Schuler, Gerold Improved transfection of eukaryontic cells with linear polynucleotides by electroporation
FR2833271B1 (fr) 2001-12-10 2004-09-17 Coletica Production de cellules dendritiques in vitro a partir de monocytes cd14+, pour notamment la realisation de modeles cellulaires et/ou tissulaires en suspension, en monocouches et tridimentionnels; utilisation de ces modeles
RU2328317C2 (ru) 2002-06-19 2008-07-10 Норсуэст Байотерапьютикс, Инк Устройство для фильтрации тангенциального потока и способы обогащения лейкоцитов
EP1389480A1 (en) * 2002-08-14 2004-02-18 Mondobiotech Interferon SA Therapeutical use of guanylhydrazones for the inhibition of CD83 dependent processes and dendritic cell maturation
EP1567014B1 (en) 2002-12-04 2011-09-28 Baylor Research Institute Rapid one-step method for generation of antigen loaded dendritic cell vaccine from precursors
CN1264974C (zh) * 2003-01-17 2006-07-19 江西医学院 白血病细胞诱导生成树突状细胞的培养基及其培养方法与应用
JP4762887B2 (ja) 2003-02-27 2011-08-31 ノースウエスト バイオセラピューティクス,インコーポレイティド 付加的なサイトカインの非存在下でgm−csfを用いる単球樹状前駆細胞からの樹状細胞の産生
EP1794327B1 (en) 2004-09-14 2016-11-30 Argos Therapeutics, Inc. Strain independent amplification of pathogens and vaccines thereto
CA2577125C (en) 2004-10-07 2016-01-12 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
US8513008B2 (en) * 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same

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