NO20075734L - Tiofenforbindelser og trombopoietin reseptoractivatorer - Google Patents
Tiofenforbindelser og trombopoietin reseptoractivatorerInfo
- Publication number
- NO20075734L NO20075734L NO20075734A NO20075734A NO20075734L NO 20075734 L NO20075734 L NO 20075734L NO 20075734 A NO20075734 A NO 20075734A NO 20075734 A NO20075734 A NO 20075734A NO 20075734 L NO20075734 L NO 20075734L
- Authority
- NO
- Norway
- Prior art keywords
- thiophene compounds
- thrombopoietin receptor
- receptor activators
- activators
- thrombopoietin
- Prior art date
Links
- 102000005763 Thrombopoietin Receptors Human genes 0.000 title 1
- 108010070774 Thrombopoietin Receptors Proteins 0.000 title 1
- 239000012190 activator Substances 0.000 title 1
- 150000003577 thiophenes Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005206822 | 2005-07-15 | ||
| JP2005206823 | 2005-07-15 | ||
| JP2006083770 | 2006-03-24 | ||
| JP2006083771 | 2006-03-24 | ||
| JP2006115569 | 2006-04-19 | ||
| PCT/JP2006/314317 WO2007010954A1 (fr) | 2005-07-15 | 2006-07-13 | Composes thiophenes et activateurs du recepteur thrombopoietine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20075734L true NO20075734L (no) | 2008-02-04 |
Family
ID=37243773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20075734A NO20075734L (no) | 2005-07-15 | 2007-11-09 | Tiofenforbindelser og trombopoietin reseptoractivatorer |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7968542B2 (fr) |
| EP (1) | EP1904472A1 (fr) |
| JP (1) | JP5071375B2 (fr) |
| KR (1) | KR101343686B1 (fr) |
| AU (1) | AU2006270801B2 (fr) |
| CA (1) | CA2609319C (fr) |
| IL (1) | IL188701A (fr) |
| NO (1) | NO20075734L (fr) |
| NZ (1) | NZ563202A (fr) |
| TW (1) | TWI368617B (fr) |
| WO (1) | WO2007010954A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA82695C2 (uk) * | 2003-06-06 | 2008-05-12 | Нисан Кемикал Индастриз, Лтд. | Гетероароматичні сполуки як активатори рецептора тромбопоетину |
| US7879318B2 (en) * | 2006-01-23 | 2011-02-01 | Mcw Research Foundation, Inc. | Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand |
| EP2025671A4 (fr) * | 2006-06-07 | 2011-04-06 | Nissan Chemical Ind Ltd | Composé hétérocyclique azoté et activateur de récepteur de thrombopoïétine |
| JP5663169B2 (ja) * | 2007-12-06 | 2015-02-04 | 日産化学工業株式会社 | ヘテロ環化合物による造血幹細胞の増幅方法 |
| TWI490214B (zh) | 2008-05-30 | 2015-07-01 | 艾德克 上野股份有限公司 | 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途 |
| EP2439204B1 (fr) * | 2009-06-04 | 2017-01-04 | Nissan Chemical Industries, Ltd. | Composé hétérocyclique et amplificateur de cellules souches hématopoïétiques |
| WO2011034962A2 (fr) * | 2009-09-16 | 2011-03-24 | Calcimedica Inc. | Composés qui modulent le calcium intracellulaire |
| WO2011049213A1 (fr) * | 2009-10-23 | 2011-04-28 | 日産化学工業株式会社 | Composés hétérocycles fusionnés et activateur du récepteur de la thrombopoïétine |
| JP2014517074A (ja) | 2011-06-24 | 2014-07-17 | アムジエン・インコーポレーテツド | Ｔｒｐｍ８アンタゴニストおよび治療におけるそれらの使用 |
| EA201490152A1 (ru) | 2011-06-24 | 2014-05-30 | Эмджен Инк. | Антагонисты trpm8 и их применение при лечении |
| KR102031386B1 (ko) | 2011-10-03 | 2019-10-11 | 닛산 가가쿠 가부시키가이샤 | 다능성 간세포로부터의 거핵구 및/또는 혈소판의 제조 방법 |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| TWI848953B (zh) | 2018-06-09 | 2024-07-21 | 德商百靈佳殷格翰國際股份有限公司 | 針對癌症治療之多特異性結合蛋白 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083913A (en) | 1995-06-07 | 2000-07-04 | Glaxo Wellcome Inc. | Peptides and compounds that bind to a thrombopoietin receptor |
| YU34196A (sh) | 1995-06-07 | 1999-03-04 | Glaxo Group Limited | Peptidi i jedinjenja koja se vezuju za receptor |
| US5869451A (en) | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| JPH1072492A (ja) | 1996-09-02 | 1998-03-17 | Hokuriku Seiyaku Co Ltd | ペプチド化合物 |
| JPH111477A (ja) | 1997-06-12 | 1999-01-06 | Hokuriku Seiyaku Co Ltd | １，４−ベンゾジアゼピン誘導体及びその用途 |
| WO1999011262A1 (fr) | 1997-09-02 | 1999-03-11 | Roche Diagnostics Gmbh | Ligands du recepteur mpl, leur procede de preparation, medicaments les contenant et leur utilisation pour le traitement et la prevention de la thrombocytopenie et l'anemie |
| JPH11152276A (ja) | 1997-11-20 | 1999-06-08 | Hokuriku Seiyaku Co Ltd | ベンゾジアゼピン誘導体 |
| GC0000177A (en) | 1998-12-17 | 2006-03-29 | Smithkline Beecham | Thrombopoietin mimetics |
| JP2002543126A (ja) | 1999-05-03 | 2002-12-17 | スミスクライン・ビーチャム・コーポレイション | Ｃｘｃｒ−４受容体アンタゴニスト−トロンボポエチン模倣物 |
| AU6023300A (en) | 1999-07-26 | 2001-02-13 | Shionogi & Co., Ltd. | Drug compositions exhibiting thrombopoietin agonism |
| JP4488663B2 (ja) | 1999-09-10 | 2010-06-23 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | トロンボポイエチン模倣物 |
| US6552008B1 (en) | 1999-09-24 | 2003-04-22 | Smithkline Beecham Corporation | Thrombopoietin mimetics |
| JP2001097948A (ja) | 1999-09-30 | 2001-04-10 | Torii Yakuhin Kk | トロンボポエチン受容体に親和性を有する化合物 |
| JP2003513965A (ja) | 1999-11-05 | 2003-04-15 | スミスクライン・ビーチャム・コーポレイション | セミカルバゾン誘導体およびそれらのトロンボポエチン模倣物としての使用 |
| EP1244446B1 (fr) | 1999-12-06 | 2006-11-02 | SmithKline Beecham Corporation | Mimetiques de thrombopoietine |
| TWI284639B (en) | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
| CY2010012I2 (el) | 2000-05-25 | 2020-05-29 | Novartis Ag | Μιμητικα θρομβοποιητινης |
| CA2436288A1 (fr) | 2000-12-19 | 2002-06-27 | Smithkline Beecham Corporation | Mimetiques de thrombopoietine |
| EP1361220A4 (fr) | 2001-01-26 | 2005-09-07 | Shionogi & Co | Composes cycliques presentant un agonisme envers le recepteur de thrombopoietine |
| KR20040025891A (ko) | 2001-01-26 | 2004-03-26 | 시오노기세이야쿠가부시키가이샤 | 트롬보포이에틴 수용체 효현작용을 갖는 할로겐 화합물 |
| EP1357116A4 (fr) | 2001-02-02 | 2005-06-01 | Yamanouchi Pharma Co Ltd | Derive de 2-acylaminothiazole ou son sel |
| EP1370252A4 (fr) | 2001-03-01 | 2006-04-05 | Smithkline Beecham Corp | Mimetiques de la thrombopoietine |
| ES2416304T3 (es) | 2002-01-18 | 2013-07-31 | Astellas Pharma Inc. | Derivado de 2-acilaminotiazol o sal del mismo |
| JP2003238565A (ja) | 2002-02-19 | 2003-08-27 | Japan Tobacco Inc | 縮合環化合物及びそれら化合物を含んでなる血球増多薬 |
| TWI324593B (en) | 2002-10-09 | 2010-05-11 | Nissan Chemical Ind Ltd | Pyrazolone compounds and thrombopoietin receptor activator |
| UA82695C2 (uk) | 2003-06-06 | 2008-05-12 | Нисан Кемикал Индастриз, Лтд. | Гетероароматичні сполуки як активатори рецептора тромбопоетину |
| KR101215207B1 (ko) | 2004-12-14 | 2012-12-26 | 닛산 가가쿠 고교 가부시키 가이샤 | 아미드 화합물 및 트롬보포이에틴 리셉터 활성화제 |
-
2006
- 2006-07-13 CA CA2609319A patent/CA2609319C/fr not_active Expired - Fee Related
- 2006-07-13 JP JP2008502169A patent/JP5071375B2/ja not_active Expired - Fee Related
- 2006-07-13 US US11/994,502 patent/US7968542B2/en not_active Expired - Fee Related
- 2006-07-13 AU AU2006270801A patent/AU2006270801B2/en not_active Ceased
- 2006-07-13 EP EP06781284A patent/EP1904472A1/fr not_active Withdrawn
- 2006-07-13 WO PCT/JP2006/314317 patent/WO2007010954A1/fr not_active Ceased
- 2006-07-13 NZ NZ563202A patent/NZ563202A/en not_active IP Right Cessation
- 2006-07-13 TW TW095125693A patent/TWI368617B/zh not_active IP Right Cessation
-
2007
- 2007-11-09 NO NO20075734A patent/NO20075734L/no not_active Application Discontinuation
-
2008
- 2008-01-10 IL IL188701A patent/IL188701A/en not_active IP Right Cessation
- 2008-01-15 KR KR1020087001205A patent/KR101343686B1/ko not_active Expired - Fee Related
-
2010
- 2010-11-29 US US12/955,477 patent/US20110092496A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL188701A (en) | 2013-08-29 |
| NZ563202A (en) | 2011-02-25 |
| EP1904472A1 (fr) | 2008-04-02 |
| CA2609319C (fr) | 2014-02-04 |
| JP2009501131A (ja) | 2009-01-15 |
| KR101343686B1 (ko) | 2013-12-20 |
| JP5071375B2 (ja) | 2012-11-14 |
| US7968542B2 (en) | 2011-06-28 |
| US20110092496A1 (en) | 2011-04-21 |
| TWI368617B (en) | 2012-07-21 |
| CA2609319A1 (fr) | 2007-01-25 |
| AU2006270801A1 (en) | 2007-01-25 |
| IL188701A0 (en) | 2008-08-07 |
| TW200728298A (en) | 2007-08-01 |
| US20090118500A1 (en) | 2009-05-07 |
| AU2006270801B2 (en) | 2011-12-22 |
| KR20080031903A (ko) | 2008-04-11 |
| WO2007010954A1 (fr) | 2007-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |