NO20072288L - Sulfonamid pert-substituerte bicykler for okklusly arteriesykdom - Google Patents
Sulfonamid pert-substituerte bicykler for okklusly arteriesykdomInfo
- Publication number
- NO20072288L NO20072288L NO20072288A NO20072288A NO20072288L NO 20072288 L NO20072288 L NO 20072288L NO 20072288 A NO20072288 A NO 20072288A NO 20072288 A NO20072288 A NO 20072288A NO 20072288 L NO20072288 L NO 20072288L
- Authority
- NO
- Norway
- Prior art keywords
- sulfonamide
- occlusly
- pert
- artery disease
- substituted
- Prior art date
Links
- 229940124530 sulfonamide Drugs 0.000 title abstract 2
- 200000000007 Arterial disease Diseases 0.000 title 1
- 208000028922 artery disease Diseases 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 Acyl sulfonamide Chemical class 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
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- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
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- Biomedical Technology (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
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Abstract
Det er beskrevet acylsulfonamid, peri-substituerte, fusjonerte bicykliske ring-forbindelser som er nyttige for behandling eller profylakse av en prostaglandinformidlet sykdom eller lidelse. Forbindelsene er av generell formel (I). Et representativt eksempel er formel (II):
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61817204P | 2004-10-12 | 2004-10-12 | |
| PCT/US2005/023009 WO2006044000A1 (en) | 2004-10-12 | 2005-06-27 | Sulfonamide pert-substituted bicyclics for occlusive artery disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20072288L true NO20072288L (no) | 2007-06-25 |
Family
ID=35229642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20072288A NO20072288L (no) | 2004-10-12 | 2007-05-02 | Sulfonamid pert-substituerte bicykler for okklusly arteriesykdom |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7598397B2 (no) |
| EP (1) | EP1812388B1 (no) |
| JP (1) | JP2008515971A (no) |
| KR (1) | KR20070091607A (no) |
| CN (1) | CN101142184A (no) |
| AT (1) | ATE499344T1 (no) |
| AU (1) | AU2005296305A1 (no) |
| BR (1) | BRPI0516003A (no) |
| CA (1) | CA2583667A1 (no) |
| DE (1) | DE602005026553D1 (no) |
| IL (1) | IL182488A0 (no) |
| MX (1) | MX2007004525A (no) |
| NO (1) | NO20072288L (no) |
| NZ (1) | NZ554491A (no) |
| RU (1) | RU2403240C2 (no) |
| WO (1) | WO2006044000A1 (no) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2580730C (en) * | 2003-09-25 | 2015-01-13 | Cenomed, Inc. | Tetrahydroindolone derivatives for treatment of neurological conditions |
| MX2007004527A (es) * | 2004-10-12 | 2007-09-21 | Decode Genetics Inc | Acidos carboxilicos biciclicos peri-sustituidos para enfermedad de arteria oclusiva. |
| JP2008515971A (ja) * | 2004-10-12 | 2008-05-15 | デコード ジェネティクス イーエイチエフ | 閉塞性動脈疾患のためのスルホンアミドぺリ置換二環式化合物 |
| JP4094660B1 (ja) * | 2005-08-10 | 2008-06-04 | 武田薬品工業株式会社 | 糖尿病治療剤 |
| CA2652152A1 (en) * | 2006-05-16 | 2007-11-29 | Decode Genetics Ehf | Process for preparing 7-(acryloyl)indoles |
| WO2007137040A2 (en) * | 2006-05-16 | 2007-11-29 | Decode Genetics Ehf | 7-(acryloyl) indole compositions and methods for making and using same |
| EP2035376B1 (en) * | 2006-06-12 | 2014-08-27 | Merck Canada Inc. | Indoline amide derivatives as ep4 receptor ligands |
| US20100069380A1 (en) * | 2006-09-22 | 2010-03-18 | Soongyu Choi | Heterocyclic inhibitors of bacterial peptidyl trna hydrolase and uses thereof |
| US8101644B2 (en) | 2007-03-30 | 2012-01-24 | Shionogi & Co., Ltd. | Pyrrolinone derivative and pharmaceutical composition comprising the same |
| EP2219648A4 (en) * | 2007-11-09 | 2010-11-03 | Cenomed Biosciences Llc | TREATMENT OF POSTRAUMATIC STRESS WITH TETRAHYDROINDOLONE ARYLPIPERAZINE COMPOUNDS |
| US20090264443A1 (en) * | 2008-04-18 | 2009-10-22 | David Helton | Treatment of organophosphate exposure with tetrahydroindolone arylpiperazine compounds |
| EP2355824A4 (en) * | 2008-11-21 | 2012-11-07 | Iroko Cardio Llc | METHOD FOR REDUCING THROMBOCYTOPENIA AND THROMBOZYTOPENIC IMPORTANT MORTALITY |
| AR086411A1 (es) | 2011-05-20 | 2013-12-11 | Nippon Soda Co | Compuesto heterociclico conteniendo nitrogeno y fungicida para el uso en agricultura y jardineria |
| JP5841361B2 (ja) * | 2011-06-29 | 2016-01-13 | 壽製薬株式会社 | 三環性化合物及びそれを含有する医薬組成物 |
| WO2014005274A1 (zh) * | 2012-07-03 | 2014-01-09 | 海南卫康制药(潜山)有限公司 | 多取代的8-氮杂环【3.2.1】辛烷化合物 |
| KR102684436B1 (ko) | 2015-10-16 | 2024-07-15 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | Ep4 길항제 |
| US20210253562A1 (en) * | 2018-07-03 | 2021-08-19 | Janssen Pharmaceutica Nv | Acylsufonamide compounds useful as ep3 receptor antagonists |
| CN112552450A (zh) * | 2019-09-10 | 2021-03-26 | 天津大学 | 一种单离子交替共聚物锂盐及其制备方法 |
| WO2024206284A2 (en) * | 2023-03-27 | 2024-10-03 | Rutgers, The State University Of New Jersey | Therapeutic compounds |
| CN119100992B (zh) * | 2023-06-02 | 2025-09-16 | 帕潘纳(北京)科技有限公司 | 一种特戈拉赞中间体及其衍生物的制备方法 |
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| JPS5030632B2 (no) * | 1971-11-29 | 1975-10-02 | ||
| DK151884C (da) * | 1979-03-07 | 1988-06-13 | Pfizer | Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf |
| GB8927981D0 (en) * | 1989-12-11 | 1990-02-14 | Ici Plc | Carbamoyl derivative |
| US5545644A (en) * | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
| CA2062587A1 (en) * | 1991-03-11 | 1992-09-12 | Toshiaki Kumazawa | Indole derivatives |
| GB9122590D0 (en) * | 1991-10-24 | 1991-12-04 | Lilly Industries Ltd | Pharmaceutical compounds |
| JPH06297860A (ja) * | 1993-04-14 | 1994-10-25 | New Oji Paper Co Ltd | 感熱記録体 |
| GB9412719D0 (en) * | 1994-06-24 | 1994-08-17 | Erba Carlo Spa | Substituted azaindolylidene compounds and process for their preparation |
| AU3578495A (en) * | 1994-09-30 | 1996-04-26 | Nippon Chemiphar Co. Ltd. | Quinoline derivative |
| WO1997005091A1 (en) * | 1995-07-26 | 1997-02-13 | Ono Pharmaceutical Co., Ltd. | Naphthyloxyacetic acid derivatives and drugs comprising the same as active ingredients |
| US6166219A (en) * | 1995-12-28 | 2000-12-26 | Fujisawa Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
| US5994378A (en) * | 1996-01-22 | 1999-11-30 | Fujisawa Pharmaceutical Co., Ltd. | Thiazolylbenzofuran derivatives and pharmaceutical compositions containing them |
| CA2258728C (en) * | 1996-06-19 | 2011-09-27 | Rhone Poulenc Rorer Limited | Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase |
| ZA984040B (en) * | 1997-05-15 | 1998-11-20 | Ono Pharmaceutical Co | Benzenesulfonamide compounds |
| RU2199532C2 (ru) * | 1997-06-27 | 2003-02-27 | Фудзисава Фармасьютикал Ко., Лтд. | Сульфонамидное соединение |
| JP3256513B2 (ja) * | 1998-02-11 | 2002-02-12 | ファイザー製薬株式会社 | ベンゾイミダゾールシクロオキシゲナーゼ−2阻害剤 |
| US6242493B1 (en) * | 1998-03-13 | 2001-06-05 | Merck Frosst Canada & Co. | Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment |
| WO2000024393A1 (en) * | 1998-10-23 | 2000-05-04 | Merck Frosst Canada & Co. | Combination product comprising an e-type prostaglandin ligand and a cox-2 selective inhibitor and methods of use |
| US6348032B1 (en) * | 1998-11-23 | 2002-02-19 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with benzimidazole derivatives |
| AU2001278771A1 (en) * | 2000-08-22 | 2002-03-04 | Ono Pharmaceutical Co. Ltd. | Carboxylic acid derivatives, process for producing the same and drugs containingthe same as the active ingredient |
| TWI314457B (no) | 2001-03-19 | 2009-09-11 | Shionogi & Co | |
| BR0211810A (pt) * | 2001-08-09 | 2004-08-24 | Ono Pharmaceutical Co | Derivados ácido carboxìlico e agente farmacêutico compreendendo os mesmos como ingrediente ativo |
| JP2008515971A (ja) * | 2004-10-12 | 2008-05-15 | デコード ジェネティクス イーエイチエフ | 閉塞性動脈疾患のためのスルホンアミドぺリ置換二環式化合物 |
| WO2007137040A2 (en) * | 2006-05-16 | 2007-11-29 | Decode Genetics Ehf | 7-(acryloyl) indole compositions and methods for making and using same |
-
2005
- 2005-06-27 JP JP2007536680A patent/JP2008515971A/ja active Pending
- 2005-06-27 US US11/169,161 patent/US7598397B2/en not_active Expired - Fee Related
- 2005-06-27 MX MX2007004525A patent/MX2007004525A/es active IP Right Grant
- 2005-06-27 DE DE602005026553T patent/DE602005026553D1/de not_active Expired - Lifetime
- 2005-06-27 CA CA002583667A patent/CA2583667A1/en not_active Abandoned
- 2005-06-27 RU RU2007115410/04A patent/RU2403240C2/ru not_active IP Right Cessation
- 2005-06-27 AU AU2005296305A patent/AU2005296305A1/en not_active Abandoned
- 2005-06-27 AT AT05769472T patent/ATE499344T1/de not_active IP Right Cessation
- 2005-06-27 BR BRPI0516003-0A patent/BRPI0516003A/pt not_active IP Right Cessation
- 2005-06-27 EP EP05769472A patent/EP1812388B1/en not_active Expired - Lifetime
- 2005-06-27 CN CNA2005800426037A patent/CN101142184A/zh active Pending
- 2005-06-27 NZ NZ554491A patent/NZ554491A/en not_active IP Right Cessation
- 2005-06-27 KR KR1020077010837A patent/KR20070091607A/ko not_active Ceased
- 2005-06-27 WO PCT/US2005/023009 patent/WO2006044000A1/en not_active Ceased
-
2007
- 2007-04-11 IL IL182488A patent/IL182488A0/en unknown
- 2007-05-02 NO NO20072288A patent/NO20072288L/no not_active Application Discontinuation
-
2009
- 2009-08-03 US US12/534,390 patent/US20090291948A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101142184A (zh) | 2008-03-12 |
| WO2006044000A1 (en) | 2006-04-27 |
| JP2008515971A (ja) | 2008-05-15 |
| EP1812388B1 (en) | 2011-02-23 |
| CA2583667A1 (en) | 2006-04-27 |
| EP1812388A1 (en) | 2007-08-01 |
| BRPI0516003A (pt) | 2008-04-29 |
| MX2007004525A (es) | 2007-09-19 |
| KR20070091607A (ko) | 2007-09-11 |
| US20060079520A1 (en) | 2006-04-13 |
| RU2007115410A (ru) | 2008-11-10 |
| DE602005026553D1 (de) | 2011-04-07 |
| RU2403240C2 (ru) | 2010-11-10 |
| NZ554491A (en) | 2009-07-31 |
| US7598397B2 (en) | 2009-10-06 |
| ATE499344T1 (de) | 2011-03-15 |
| US20090291948A1 (en) | 2009-11-26 |
| IL182488A0 (en) | 2007-09-20 |
| AU2005296305A1 (en) | 2006-04-27 |
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