NO20072208L - Syklopropylpiperidinglysintransportorinhibitorer. - Google Patents
Syklopropylpiperidinglysintransportorinhibitorer.Info
- Publication number
- NO20072208L NO20072208L NO20072208A NO20072208A NO20072208L NO 20072208 L NO20072208 L NO 20072208L NO 20072208 A NO20072208 A NO 20072208A NO 20072208 A NO20072208 A NO 20072208A NO 20072208 L NO20072208 L NO 20072208L
- Authority
- NO
- Norway
- Prior art keywords
- glycine transporter
- transporter glyt1
- syklopropylpiperidinglysintransportorinhibitorer
- glycinergic
- glutamatergic
- Prior art date
Links
- 102000010726 Glycine Plasma Membrane Transport Proteins Human genes 0.000 abstract 2
- 108010063380 Glycine Plasma Membrane Transport Proteins Proteins 0.000 abstract 2
- 102100023145 Sodium- and chloride-dependent glycine transporter 1 Human genes 0.000 abstract 2
- 101710083171 Sodium- and chloride-dependent glycine transporter 1 Proteins 0.000 abstract 2
- JUBXTBVKELTJEX-UHFFFAOYSA-N 1-cyclopropylpiperidine Chemical class C1CC1N1CCCCC1 JUBXTBVKELTJEX-UHFFFAOYSA-N 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
- 230000024587 synaptic transmission, glutamatergic Effects 0.000 abstract 1
- 230000027682 synaptic transmission, glycinergic Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61494204P | 2004-09-30 | 2004-09-30 | |
| PCT/US2005/034301 WO2006039221A2 (fr) | 2004-09-30 | 2005-09-26 | Inhibiteurs du transporteur de la glycine de piperidine de cyclopropyle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20072208L true NO20072208L (no) | 2007-04-27 |
Family
ID=36142986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20072208A NO20072208L (no) | 2004-09-30 | 2007-04-27 | Syklopropylpiperidinglysintransportorinhibitorer. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7776886B2 (fr) |
| EP (1) | EP1797035B1 (fr) |
| JP (1) | JP4646984B2 (fr) |
| KR (1) | KR20070058565A (fr) |
| CN (1) | CN101031547A (fr) |
| AT (1) | ATE488501T1 (fr) |
| AU (1) | AU2005292323B2 (fr) |
| BR (1) | BRPI0515954A (fr) |
| CA (1) | CA2581582C (fr) |
| DE (1) | DE602005024838D1 (fr) |
| IL (1) | IL182253A0 (fr) |
| MX (1) | MX2007003816A (fr) |
| NO (1) | NO20072208L (fr) |
| RU (1) | RU2387644C2 (fr) |
| WO (1) | WO2006039221A2 (fr) |
| ZA (1) | ZA200701612B (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004289290A1 (en) * | 2003-11-12 | 2005-05-26 | Merck & Co., Inc. | 4-phenyl piperdine sulfonyl glycine transporter inhibitors |
| AU2005228133B2 (en) * | 2004-03-24 | 2011-09-08 | Merck Sharp & Dohme Corp. | Heteroaryl piperidine glycine transporter inhibitors |
| EP1745018A1 (fr) * | 2004-04-29 | 2007-01-24 | Merck & Co., Inc. | Inhibiteurs de transporteur de glycine à base d'azétidine |
| US7576083B2 (en) * | 2004-05-05 | 2009-08-18 | Merck & Co., Inc. | Morpholinyl piperidine glycine transporter inhibitors |
| JP5055493B2 (ja) * | 2004-12-21 | 2012-10-24 | メルク シャープ エンド ドーム リミテッド | Ｇｌｙｔ１阻害薬としてのピペリジンおよびアゼチジン誘導体 |
| TW200716531A (en) * | 2005-06-06 | 2007-05-01 | Merck Sharp & Dohme | Cyclohexanesulfonyl derivatives as GLYT1 inhibitors to treat schizophrenia |
| WO2006134341A1 (fr) | 2005-06-13 | 2006-12-21 | Merck Sharp & Dohme Limited | Agents therapeutiques |
| AU2006309050B2 (en) | 2005-10-28 | 2012-08-16 | Merck Sharp & Dohme Corp. | Piperidine glycine transporter inhibitors |
| EP2403337A4 (fr) * | 2009-03-03 | 2012-08-15 | Univ Vanderbilt | Analogues d'alkylsulfonyl-2,3-dihydrospiro[indène-1,4'-pipéridine] en tant qu'inhibiteurs de glyt1, leurs procédés de fabrication et leur utilisation dans le traitement de troubles psychiatriques |
| WO2015164520A1 (fr) | 2014-04-24 | 2015-10-29 | Dart Neuroscience, Llc | Composés de 2,4,5,6-tétrahydropyrrolo[3,4-c] pyrazole et 4,5,6,7-tétrahydro-2 h-pyrazolo [4,3-c] pyridine utilisés comme inhibiteurs de glyt1 |
| US10040759B2 (en) | 2014-11-05 | 2018-08-07 | Dart Neuroscience (Cayman) Ltd. | Substituted azetidinyl compounds as GlyT1 inhibitors |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5532237A (en) | 1995-02-15 | 1996-07-02 | Merck Frosst Canada, Inc. | Indole derivatives with affinity for the cannabinoid receptor |
| US6303637B1 (en) * | 1998-10-30 | 2001-10-16 | Merck & Co., Inc. | Heterocyclic potassium channel inhibitors |
| CA2397981C (fr) * | 2000-03-06 | 2010-12-21 | Acadia Pharmaceuticals, Inc. | Composes azacycliques utilises dans le traitement de maladies liees a la serotonine |
| CA2403686C (fr) * | 2000-03-23 | 2010-01-26 | Merck & Co., Inc. | Piperidines substituees en tant qu'agonistes du recepteur de la melanocortine |
| US7507767B2 (en) | 2001-02-08 | 2009-03-24 | Schering Corporation | Cannabinoid receptor ligands |
| WO2003042174A1 (fr) * | 2001-11-14 | 2003-05-22 | Schering Corporation | Ligands du recepteur des cannabinoides |
| GB0130696D0 (en) * | 2001-12-21 | 2002-02-06 | Smithkline Beecham Plc | Chemical Compounds |
| TW200403058A (en) | 2002-04-19 | 2004-03-01 | Bristol Myers Squibb Co | Heterocyclo inhibitors of potassium channel function |
| AU2004289290A1 (en) | 2003-11-12 | 2005-05-26 | Merck & Co., Inc. | 4-phenyl piperdine sulfonyl glycine transporter inhibitors |
| AU2005228133B2 (en) * | 2004-03-24 | 2011-09-08 | Merck Sharp & Dohme Corp. | Heteroaryl piperidine glycine transporter inhibitors |
| EP1745018A1 (fr) * | 2004-04-29 | 2007-01-24 | Merck & Co., Inc. | Inhibiteurs de transporteur de glycine à base d'azétidine |
| US7576083B2 (en) * | 2004-05-05 | 2009-08-18 | Merck & Co., Inc. | Morpholinyl piperidine glycine transporter inhibitors |
| JP5055493B2 (ja) * | 2004-12-21 | 2012-10-24 | メルク シャープ エンド ドーム リミテッド | Ｇｌｙｔ１阻害薬としてのピペリジンおよびアゼチジン誘導体 |
| TW200716531A (en) * | 2005-06-06 | 2007-05-01 | Merck Sharp & Dohme | Cyclohexanesulfonyl derivatives as GLYT1 inhibitors to treat schizophrenia |
| EP1942733B1 (fr) | 2005-09-29 | 2012-03-21 | Merck Sharp & Dohme Corp. | Inhibiteurs radiomarqués de transporteurs de glycine |
| AU2006309050B2 (en) | 2005-10-28 | 2012-08-16 | Merck Sharp & Dohme Corp. | Piperidine glycine transporter inhibitors |
-
2005
- 2005-09-26 RU RU2007116165/04A patent/RU2387644C2/ru not_active IP Right Cessation
- 2005-09-26 CA CA2581582A patent/CA2581582C/fr not_active Expired - Lifetime
- 2005-09-26 CN CNA2005800331179A patent/CN101031547A/zh active Pending
- 2005-09-26 WO PCT/US2005/034301 patent/WO2006039221A2/fr not_active Ceased
- 2005-09-26 KR KR1020077007362A patent/KR20070058565A/ko not_active Withdrawn
- 2005-09-26 JP JP2007534679A patent/JP4646984B2/ja not_active Expired - Fee Related
- 2005-09-26 US US11/664,190 patent/US7776886B2/en active Active
- 2005-09-26 BR BRPI0515954-7A patent/BRPI0515954A/pt not_active IP Right Cessation
- 2005-09-26 AT AT05801197T patent/ATE488501T1/de not_active IP Right Cessation
- 2005-09-26 AU AU2005292323A patent/AU2005292323B2/en not_active Ceased
- 2005-09-26 MX MX2007003816A patent/MX2007003816A/es active IP Right Grant
- 2005-09-26 EP EP05801197A patent/EP1797035B1/fr not_active Expired - Lifetime
- 2005-09-26 DE DE602005024838T patent/DE602005024838D1/de not_active Expired - Lifetime
-
2007
- 2007-02-23 ZA ZA200701612A patent/ZA200701612B/xx unknown
- 2007-03-27 IL IL182253A patent/IL182253A0/en unknown
- 2007-04-27 NO NO20072208A patent/NO20072208L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005292323A1 (en) | 2006-04-13 |
| MX2007003816A (es) | 2007-04-24 |
| CA2581582C (fr) | 2010-07-20 |
| KR20070058565A (ko) | 2007-06-08 |
| EP1797035A4 (fr) | 2009-08-05 |
| US7776886B2 (en) | 2010-08-17 |
| RU2007116165A (ru) | 2008-11-10 |
| BRPI0515954A (pt) | 2008-08-12 |
| CN101031547A (zh) | 2007-09-05 |
| JP2008514705A (ja) | 2008-05-08 |
| US20080108663A1 (en) | 2008-05-08 |
| CA2581582A1 (fr) | 2006-04-13 |
| RU2387644C2 (ru) | 2010-04-27 |
| EP1797035B1 (fr) | 2010-11-17 |
| DE602005024838D1 (en) | 2010-12-30 |
| ZA200701612B (en) | 2009-05-27 |
| JP4646984B2 (ja) | 2011-03-09 |
| WO2006039221A3 (fr) | 2006-09-08 |
| IL182253A0 (en) | 2007-09-20 |
| EP1797035A2 (fr) | 2007-06-20 |
| ATE488501T1 (de) | 2010-12-15 |
| AU2005292323B2 (en) | 2011-06-09 |
| WO2006039221A2 (fr) | 2006-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |