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NO20064366L - Tiazolderivat - Google Patents

Tiazolderivat

Info

Publication number
NO20064366L
NO20064366L NO20064366A NO20064366A NO20064366L NO 20064366 L NO20064366 L NO 20064366L NO 20064366 A NO20064366 A NO 20064366A NO 20064366 A NO20064366 A NO 20064366A NO 20064366 L NO20064366 L NO 20064366L
Authority
NO
Norway
Prior art keywords
derivative
salt
phenyl
pyridyl
heteroaromatic ring
Prior art date
Application number
NO20064366A
Other languages
English (en)
Inventor
Hajime Asanuma
Masakazu Sato
Yuko Matsunaga
Hideaki Amada
Takeshi Koami
Tetsuo Takayama
Tetsuya Yabuuchi
Fumiyasu Shiozawa
Hironori Katakai
Hiroki Umemiya
Akiko Ikeda
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of NO20064366L publication Critical patent/NO20064366L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Tiazolylimidazolderivat representert ved formelen hvori X1 og X2 er forskjellig fra hverandre og representerer et svovelatom eller et karbonatom; R1 representerer fenyl, substituert fenyl, fenyl sammensmeltet med en heteroaromatisk ring, en pyridyl eller pyridyl sammensmeltet med en heteroaromatisk ring; R2 representerer hydrogen, halogen, C1-C6 alkyl, C1-C6 alkyl substituert med ett eller flere halogenatomer, C1-C6 alkoksy, C1-C6 alkanoyl eller C1-C5 hydroksyalkyl; og A representerer en gruppe representert ved følgende formel) eller et farmasøytisk akseptabelt salt eller derivat; og en ALK 5 inhibitor, terapeutisk middel for alopeci eller hårgjenoppretter som hver inneholder derivatet eller saltet som en aktiv ingrediens. Derivatet eller saltet er en substans som inhiberer ALK 5, som er en TGB-( type-I-reseptor. Hårvekstpreparatet eller hårgjenoppretterne er basert på en ny funksjon.
NO20064366A 2004-03-05 2006-09-26 Tiazolderivat NO20064366L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004062321 2004-03-05
JP2004344307 2004-11-29
PCT/JP2005/003755 WO2005085241A1 (ja) 2004-03-05 2005-03-04 チアゾール誘導体

Publications (1)

Publication Number Publication Date
NO20064366L true NO20064366L (no) 2006-11-08

Family

ID=34921704

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064366A NO20064366L (no) 2004-03-05 2006-09-26 Tiazolderivat

Country Status (13)

Country Link
US (2) US7678810B2 (no)
EP (1) EP1721905A4 (no)
JP (1) JP4853284B2 (no)
KR (1) KR101150077B1 (no)
AU (1) AU2005219737B2 (no)
BR (1) BRPI0508397A (no)
CA (1) CA2556944C (no)
MY (1) MY146532A (no)
NO (1) NO20064366L (no)
NZ (1) NZ549003A (no)
RU (1) RU2367661C2 (no)
WO (1) WO2005085241A1 (no)
ZA (1) ZA200606734B (no)

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Also Published As

Publication number Publication date
EP1721905A4 (en) 2009-11-18
RU2367661C2 (ru) 2009-09-20
JP4853284B2 (ja) 2012-01-11
KR20060124744A (ko) 2006-12-05
HK1104543A1 (zh) 2008-01-18
ZA200606734B (en) 2008-01-08
MY146532A (en) 2012-08-15
KR101150077B1 (ko) 2012-06-01
EP1721905A1 (en) 2006-11-15
AU2005219737A1 (en) 2005-09-15
RU2006135111A (ru) 2008-04-10
JPWO2005085241A1 (ja) 2008-01-17
US7678810B2 (en) 2010-03-16
CA2556944C (en) 2012-10-09
US20100216787A1 (en) 2010-08-26
CA2556944A1 (en) 2005-09-15
WO2005085241A1 (ja) 2005-09-15
AU2005219737B2 (en) 2009-11-19
BRPI0508397A (pt) 2007-08-07
NZ549003A (en) 2009-07-31
US20070154428A1 (en) 2007-07-05

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