NO20064450L - Pyrazolo [3,4- β] Pyridin-forbindelse og dennes anvendelse som PDE4-inhibitor - Google Patents
Pyrazolo [3,4- β] Pyridin-forbindelse og dennes anvendelse som PDE4-inhibitorInfo
- Publication number
- NO20064450L NO20064450L NO20064450A NO20064450A NO20064450L NO 20064450 L NO20064450 L NO 20064450L NO 20064450 A NO20064450 A NO 20064450A NO 20064450 A NO20064450 A NO 20064450A NO 20064450 L NO20064450 L NO 20064450L
- Authority
- NO
- Norway
- Prior art keywords
- compound
- pyrazolo
- mammal
- provides
- salt
- Prior art date
Links
- -1 pyridine compound Chemical class 0.000 title abstract 2
- 229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 title 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 title 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 241000124008 Mammalia Species 0.000 abstract 3
- 230000002265 prevention Effects 0.000 abstract 2
- 238000011200 topical administration Methods 0.000 abstract 2
- 208000028698 Cognitive impairment Diseases 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0405893A GB0405893D0 (en) | 2004-03-16 | 2004-03-16 | Compounds |
| GB0505214A GB0505214D0 (en) | 2005-03-14 | 2005-03-14 | Compounds |
| PCT/EP2005/003038 WO2005090352A1 (fr) | 2004-03-16 | 2005-03-15 | Compose de pyrazolo[3,4-b]pyridine, et son utilisation en tant qu'inhibiteur de pdea4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20064450L true NO20064450L (no) | 2006-11-14 |
Family
ID=34962723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20064450A NO20064450L (no) | 2004-03-16 | 2006-10-02 | Pyrazolo [3,4- β] Pyridin-forbindelse og dennes anvendelse som PDE4-inhibitor |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US7709497B2 (fr) |
| EP (2) | EP1735314A1 (fr) |
| JP (2) | JP2007529464A (fr) |
| KR (1) | KR20060130744A (fr) |
| AR (1) | AR048175A1 (fr) |
| AU (1) | AU2005223351A1 (fr) |
| BR (1) | BRPI0508843A (fr) |
| CA (1) | CA2559629A1 (fr) |
| IL (1) | IL178011A0 (fr) |
| MA (1) | MA28531B1 (fr) |
| NO (1) | NO20064450L (fr) |
| PE (1) | PE20060078A1 (fr) |
| RU (1) | RU2378274C2 (fr) |
| TW (1) | TW200602051A (fr) |
| WO (2) | WO2005090354A1 (fr) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0230045D0 (en) | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
| US20070111995A1 (en) * | 2003-12-19 | 2007-05-17 | Allen David G | Pyrazolo [3,4-B] pyridine Compounds and Their Use as Phosphodiesterase Inhibitors |
| EP1735314A1 (fr) | 2004-03-16 | 2006-12-27 | Glaxo Group Limited | Compose de pyrazolo [3,4-b]pyridine, et son utilisation en tant qu'inhibiteur de pdea4 |
| AU2007242851A1 (en) | 2006-04-20 | 2007-11-01 | Glaxo Group Limited | Novel compounds |
| PE20080943A1 (es) | 2006-06-23 | 2008-09-27 | Smithkline Beecham Corp | Sal toluenosulfonato de 4-{[6-cloro-3-({[(2-cloro-3-fluorofenil)amino]carbonil}amino)-2-hidroxifenil]sulfonil}-1-piperazinacarboxilato de 1,1-dimetiletilo como antagonista del receptor de il-8 |
| DK2046787T3 (da) | 2006-08-01 | 2011-07-18 | Glaxo Group Ltd | Pyrazolo[3,4-B]pyridin-forbindelser, og deres anvendelse som PDE4-inhibitorer |
| AR065804A1 (es) | 2007-03-23 | 2009-07-01 | Smithkline Beecham Corp | Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento |
| AR070563A1 (es) | 2008-02-06 | 2010-04-21 | Glaxo Group Ltd | Compuesto de un biciclo condensado pirazol-piridin-amina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento util para el tratamiento de enfermedades respiratorias. |
| UY31635A1 (es) | 2008-02-06 | 2009-08-31 | Farmacóforos duales-antagonistas muscarínicos de pde4 | |
| TW201000476A (en) | 2008-02-06 | 2010-01-01 | Glaxo Group Ltd | Dual pharmacophores-PDE4-muscarinic antagonistics |
| EP2249646A4 (fr) * | 2008-02-06 | 2013-09-25 | Glaxo Group Ltd | Pharmacophores duals, antagonistes des récepteurs muscariniques et inhibiteurs de l'activité pde4 |
| GB0806900D0 (en) * | 2008-04-16 | 2008-05-21 | Dow Corning | Fabric care emulsions |
| US8163743B2 (en) | 2008-06-05 | 2012-04-24 | GlaxoGroupLimited | 4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases |
| CA2749403A1 (fr) | 2009-01-13 | 2010-09-02 | Glaxo Group Limited | Derives de pyrimidine carboxamide comme inhibiteurs de la kinase syk |
| JP5656880B2 (ja) | 2009-03-09 | 2015-01-21 | グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ | Ｐｉ３キナーゼの阻害剤としての４−オキサジアゾール−２−イル−インダゾール |
| US8354539B2 (en) | 2009-03-10 | 2013-01-15 | Glaxo Group Limited | Indole derivatives as IKK2 inhibitors |
| EP2408769A1 (fr) | 2009-03-17 | 2012-01-25 | Glaxo Group Limited | Dérivés de pyrimidine utilisés comme inhibiteurs de ltk |
| CA2795611C (fr) * | 2009-04-13 | 2016-09-20 | Sulur Subramaniam Vanangamudi | Creme medicinale a base d'acide fusidique produite au moyen de fusidate de sodium et incorporant un biopolymere et son procede de fabrication |
| MY160454A (en) | 2009-04-30 | 2017-03-15 | Glaxo Group Ltd | Oxazole substituted indazoles as pi3-kinase inhibitors |
| WO2011067364A1 (fr) | 2009-12-03 | 2011-06-09 | Glaxo Group Limited | Nouveaux composés |
| US20120245171A1 (en) | 2009-12-03 | 2012-09-27 | Glaxo Group Limited | Benzpyrazole derivatives as inhibitors of pi3 kinases |
| WO2011067366A1 (fr) | 2009-12-03 | 2011-06-09 | Glaxo Group Limited | Dérivés d'indazole comme inhibiteurs des pi3-kinases |
| WO2011110575A1 (fr) | 2010-03-11 | 2011-09-15 | Glaxo Group Limited | Dérivés de 2-[2-(benzo- ou pyrido-)thiazolylamino]-6- aminopyridine, utiles dans le traitement de maladies respiratoires, allergiques ou inflammatoires |
| US9326987B2 (en) | 2010-09-08 | 2016-05-03 | Glaxo Group Limited | Indazole derivatives for use in the treatment of influenza virus infection |
| DK2614058T3 (en) | 2010-09-08 | 2015-09-28 | Glaxosmithkline Ip Dev Ltd | Polymorphs, and the salts of N- [5- [4- (5 - {[(2R, 6S) -2,6-dimethyl-4-morpholinyl] methyl} -1,3-oxazol-2-yl) -1H-indazole -6-yl] -2- (methyloxy) -3-pyridinyl] methanesulfonamide. |
| WO2012035055A1 (fr) | 2010-09-17 | 2012-03-22 | Glaxo Group Limited | Nouveaux composés |
| GB201018124D0 (en) | 2010-10-27 | 2010-12-08 | Glaxo Group Ltd | Polymorphs and salts |
| KR102142162B1 (ko) | 2012-08-27 | 2020-09-14 | 에이비 엘렉트로룩스 | 로봇 위치 선정 시스템 |
| CN105101854A (zh) | 2013-04-15 | 2015-11-25 | 伊莱克斯公司 | 机器人真空吸尘器 |
| WO2014169944A1 (fr) | 2013-04-15 | 2014-10-23 | Aktiebolaget Electrolux | Dispositif de nettoyage sous vide robotisé avec brosse latérale saillante |
| US9011934B2 (en) | 2013-06-14 | 2015-04-21 | SatisPharma, LLC | Multi-purpose anti-itch treatment |
| AU2014336251A1 (en) | 2013-10-17 | 2016-04-14 | Glaxosmithkline Intellectual Property Development Limited | PI3K inhibitor for treatment of respiratory disease |
| RU2016112268A (ru) | 2013-10-17 | 2017-11-22 | Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Ингибитор PI3K для лечения респираторного заболевания |
| CN105813526B (zh) | 2013-12-19 | 2021-08-24 | 伊莱克斯公司 | 机器人清扫装置以及用于地标识别的方法 |
| KR102099495B1 (ko) | 2013-12-19 | 2020-04-09 | 에이비 엘렉트로룩스 | 로봇 청소 장치가 장애물에 올라가는 것의 감지 |
| CN105744872B (zh) | 2013-12-19 | 2020-01-14 | 伊莱克斯公司 | 旋转侧刷的自适应速度控制 |
| WO2015090404A1 (fr) | 2013-12-19 | 2015-06-25 | Aktiebolaget Electrolux | Priorisation de zones de nettoyage |
| ES2656664T3 (es) | 2013-12-19 | 2018-02-28 | Aktiebolaget Electrolux | Dispositivo robótico de limpieza con función de registro del perímetro |
| EP3084540B1 (fr) | 2013-12-19 | 2021-04-14 | Aktiebolaget Electrolux | Robot de nettoyage et methode d'exploitation associee |
| WO2015090398A1 (fr) | 2013-12-19 | 2015-06-25 | Aktiebolaget Electrolux | Aspirateur robotique ayant une brosse latérale se déplaçant en spirale |
| CN105848545B (zh) | 2013-12-20 | 2019-02-19 | 伊莱克斯公司 | 灰尘容器 |
| EA201692111A1 (ru) | 2014-05-12 | 2017-08-31 | Глаксосмитклайн Интеллекчуал Проперти (№ 2) Лимитед | Фармацевтические композиции, содержащие данириксин, для лечения инфекционных заболеваний |
| CN106415423B (zh) | 2014-07-10 | 2021-01-01 | 伊莱克斯公司 | 用于检测机器人清洁装置的测量误差的方法 |
| KR102271785B1 (ko) | 2014-09-08 | 2021-06-30 | 에이비 엘렉트로룩스 | 로봇 진공 청소기 |
| US10729297B2 (en) | 2014-09-08 | 2020-08-04 | Aktiebolaget Electrolux | Robotic vacuum cleaner |
| US9452178B1 (en) | 2014-10-22 | 2016-09-27 | SatisPharma, LLC | Acne formulations, treatments, and pressure sensitive patches for delivery of acne formulations |
| CN106998980B (zh) | 2014-12-10 | 2021-12-17 | 伊莱克斯公司 | 使用激光传感器检测地板类型 |
| WO2016091320A1 (fr) | 2014-12-12 | 2016-06-16 | Aktiebolaget Electrolux | Brosse latérale et dispositif de nettoyage robotisé |
| WO2016095965A2 (fr) | 2014-12-16 | 2016-06-23 | Aktiebolaget Electrolux | Feuille de route basée sur l'expérience pour un dispositif de nettoyage robotisé |
| WO2016095966A1 (fr) | 2014-12-16 | 2016-06-23 | Aktiebolaget Electrolux | Procédé de nettoyage pour un dispositif de nettoyage robotisé |
| EP3282912B1 (fr) | 2015-04-17 | 2020-06-10 | Aktiebolaget Electrolux | Dispositif robotique de nettoyage et un procédé de contrôle pour le dispositif robotique de nettoyage |
| KR102445064B1 (ko) | 2015-09-03 | 2022-09-19 | 에이비 엘렉트로룩스 | 로봇 청소 장치의 시스템 |
| PT3359541T (pt) * | 2015-10-09 | 2020-11-11 | Galapagos Nv | Pirazol[3,4-b]piridin-6-carboxamidas n-sulfoniladas e método de utilização |
| GB201602527D0 (en) | 2016-02-12 | 2016-03-30 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
| JP7035300B2 (ja) | 2016-03-15 | 2022-03-15 | アクチエボラゲット エレクトロルックス | ロボット清掃デバイス、ロボット清掃デバイスにおける、断崖検出を遂行する方法、コンピュータプログラム、およびコンピュータプログラム製品 |
| EP3454707B1 (fr) | 2016-05-11 | 2020-07-08 | Aktiebolaget Electrolux | Robot de nettoyage |
| WO2018029126A1 (fr) | 2016-08-08 | 2018-02-15 | Glaxosmithkline Intellectual Property Development Limited | Composés chimiques |
| GB201706102D0 (en) | 2017-04-18 | 2017-05-31 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
| WO2018219473A1 (fr) | 2017-06-02 | 2018-12-06 | Aktiebolaget Electrolux | Procédé de détection d'une différence de niveau d'une surface devant un dispositif de nettoyage robotisé |
| GB201712081D0 (en) | 2017-07-27 | 2017-09-13 | Glaxosmithkline Ip Dev Ltd | Chemical compounds |
| CN111093447B (zh) | 2017-09-26 | 2022-09-02 | 伊莱克斯公司 | 机器人清洁设备的移动控制 |
| KR102034538B1 (ko) * | 2017-11-28 | 2019-10-21 | 주식회사한국파마 | Jak 저해제 화합물, 및 이의 제조방법 |
| CN111875594A (zh) * | 2020-07-21 | 2020-11-03 | 中国药科大学 | 具有磷酸二酯酶4b抑制活性的吲唑杂环类化合物 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3833594A (en) * | 1971-08-05 | 1974-09-03 | Squibb & Sons Inc | Amino derivatives of pyrazolopyridine carboxylic acids and esters |
| US3925388A (en) * | 1971-08-05 | 1975-12-09 | Squibb & Sons Inc | 4-Piperazino-{8 3,4-b{9 pyridine-5-carboxylic acids and esters |
| US3856799A (en) * | 1971-08-05 | 1974-12-24 | Squibb & Sons Inc | Intermediates for production of amino derivatives of pyrazolopyridine carboxylic acids and esters |
| BE787249A (fr) * | 1971-08-05 | 1973-02-05 | Squibb & Sons Inc | Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation |
| CA1003419A (en) | 1971-11-23 | 1977-01-11 | Theodor Denzel | Process for the production of pyrazolo (3,4-b) pyridines |
| US3979399A (en) * | 1972-11-15 | 1976-09-07 | E. R. Squibb & Sons, Inc. | Amino derivatives of pyrazolopyridine carboxamides |
| US3840546A (en) * | 1972-11-15 | 1974-10-08 | Squibb & Sons Inc | Amino derivatives of pyrazolopyridine carboxamides |
| US3833598A (en) * | 1972-12-29 | 1974-09-03 | Squibb & Sons Inc | Amino derivatives of pyrazolopyridine-6-carboxylic acids and esters |
| US4115394A (en) * | 1974-05-06 | 1978-09-19 | E. R. Squibb & Sons, Inc. | Amino derivatives of 6-phenylpyrazolo[3,4-b]pyridines |
| US4364948A (en) | 1981-09-28 | 1982-12-21 | Ici Americas Inc. | Pyrazolo[3,4-b]pyridine compounds |
| GB8425104D0 (en) | 1984-10-04 | 1984-11-07 | Ici America Inc | Amide derivatives |
| US5547954A (en) * | 1994-05-26 | 1996-08-20 | Fmc Corporation | 2,4-Diamino-5,6-disubstituted-and 5,6,7-trisubstituted-5-deazapteridines as insecticides |
| US5593997A (en) * | 1995-05-23 | 1997-01-14 | Pfizer Inc. | 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors |
| US6326379B1 (en) * | 1998-09-16 | 2001-12-04 | Bristol-Myers Squibb Co. | Fused pyridine inhibitors of cGMP phosphodiesterase |
| RU2134498C1 (ru) * | 1998-12-08 | 1999-08-10 | Таран Александр Иванович | Контактный узел |
| CZ20021086A3 (cs) | 1999-09-30 | 2002-10-16 | Neurogen Corporation | Alkylendiaminem substituované heterocykly |
| GB9929685D0 (en) | 1999-12-15 | 2000-02-09 | Merck Sharp & Dohme | Therapeutic agents |
| JP2002020386A (ja) * | 2000-07-07 | 2002-01-23 | Ono Pharmaceut Co Ltd | ピラゾロピリジン誘導体 |
| US6670364B2 (en) * | 2001-01-31 | 2003-12-30 | Telik, Inc. | Antagonists of MCP-1 function and methods of use thereof |
| WO2002098878A1 (fr) | 2001-02-08 | 2002-12-12 | Memory Pharmaceuticals Corporation | Trifluoromethylpurines en tant qu'inhibiteurs de la phosphodiesterase 4 |
| TWI236474B (en) | 2001-04-03 | 2005-07-21 | Telik Inc | Antagonists of MCP-1 function and methods of use thereof |
| FR2828693B1 (fr) * | 2001-08-14 | 2004-06-18 | Exonhit Therapeutics Sa | Nouvelle cible moleculaire de la neurotoxicite |
| US20050043319A1 (en) * | 2001-08-14 | 2005-02-24 | Exonhit Therapeutics Sa | Molecular target of neurotoxicity |
| GB0230045D0 (en) * | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
| US20060089375A1 (en) * | 2002-09-16 | 2006-04-27 | Allen David G | Pyrazolo[3,4-b] pyridine compounds, and their use as phosphodiesterase inhibitors |
| US7117650B2 (en) * | 2002-12-09 | 2006-10-10 | Forrest Dockery | Hanger system |
| US20070111995A1 (en) * | 2003-12-19 | 2007-05-17 | Allen David G | Pyrazolo [3,4-B] pyridine Compounds and Their Use as Phosphodiesterase Inhibitors |
| EP1735314A1 (fr) | 2004-03-16 | 2006-12-27 | Glaxo Group Limited | Compose de pyrazolo [3,4-b]pyridine, et son utilisation en tant qu'inhibiteur de pdea4 |
| GB0405933D0 (en) | 2004-03-16 | 2004-04-21 | Glaxo Group Ltd | Compounds |
| GB0405937D0 (en) | 2004-03-16 | 2004-04-21 | Glaxo Group Ltd | Compounds |
-
2005
- 2005-03-15 EP EP05716291A patent/EP1735314A1/fr not_active Withdrawn
- 2005-03-15 BR BRPI0508843-7A patent/BRPI0508843A/pt not_active IP Right Cessation
- 2005-03-15 WO PCT/GB2005/000987 patent/WO2005090354A1/fr not_active Ceased
- 2005-03-15 US US10/598,838 patent/US7709497B2/en not_active Expired - Fee Related
- 2005-03-15 AU AU2005223351A patent/AU2005223351A1/en not_active Abandoned
- 2005-03-15 EP EP05718039A patent/EP1740590A1/fr not_active Withdrawn
- 2005-03-15 WO PCT/EP2005/003038 patent/WO2005090352A1/fr not_active Ceased
- 2005-03-15 RU RU2006132684/04A patent/RU2378274C2/ru not_active IP Right Cessation
- 2005-03-15 JP JP2007503306A patent/JP2007529464A/ja active Pending
- 2005-03-15 JP JP2007503404A patent/JP2007529486A/ja active Pending
- 2005-03-15 KR KR1020067021438A patent/KR20060130744A/ko not_active Ceased
- 2005-03-15 US US10/598,973 patent/US20080275078A1/en not_active Abandoned
- 2005-03-15 CA CA002559629A patent/CA2559629A1/fr not_active Abandoned
- 2005-03-16 AR ARP050101028A patent/AR048175A1/es not_active Application Discontinuation
- 2005-03-16 TW TW094108054A patent/TW200602051A/zh unknown
- 2005-03-16 PE PE2005000299A patent/PE20060078A1/es not_active Application Discontinuation
-
2006
- 2006-09-11 IL IL178011A patent/IL178011A0/en unknown
- 2006-10-02 NO NO20064450A patent/NO20064450L/no not_active Application Discontinuation
- 2006-10-13 MA MA29385A patent/MA28531B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20060130744A (ko) | 2006-12-19 |
| BRPI0508843A (pt) | 2007-08-28 |
| US20070280971A1 (en) | 2007-12-06 |
| RU2378274C2 (ru) | 2010-01-10 |
| IL178011A0 (en) | 2006-12-31 |
| AU2005223351A1 (en) | 2005-09-29 |
| WO2005090352A1 (fr) | 2005-09-29 |
| JP2007529464A (ja) | 2007-10-25 |
| EP1735314A1 (fr) | 2006-12-27 |
| US20080275078A1 (en) | 2008-11-06 |
| EP1740590A1 (fr) | 2007-01-10 |
| MA28531B1 (fr) | 2007-04-03 |
| US7709497B2 (en) | 2010-05-04 |
| TW200602051A (en) | 2006-01-16 |
| JP2007529486A (ja) | 2007-10-25 |
| WO2005090354A1 (fr) | 2005-09-29 |
| CA2559629A1 (fr) | 2005-09-29 |
| RU2006132684A (ru) | 2008-04-27 |
| AR048175A1 (es) | 2006-04-05 |
| PE20060078A1 (es) | 2006-03-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20064450L (no) | Pyrazolo [3,4- β] Pyridin-forbindelse og dennes anvendelse som PDE4-inhibitor | |
| NO20071776L (no) | Kinoksaliner som B RAF inhibitorer. | |
| NO20055421L (no) | Kinolinderivater som fosfodiestrase-inhibitorer | |
| NO20066055L (no) | Pyridinderivater | |
| NO20061454L (no) | Compounds having CRTH2 antagonist activity | |
| NO20084872L (no) | 2-pyridonderivater for behandling av sykdom eller tilstander der inhibering av neutrofil elastaseaktivitet er gunstig | |
| MXPA05010055A (es) | Derivados de 2-fenoxi- y 2-fenil-sulfomamida con actividad antagonista del ccr3, para el tratamiento del asma y otros desordenes inflamatorios o inmunologicos. | |
| NO20044599L (no) | 3-amino-tieno[2,3-b]pyridin-2-karboksysyreamid-forbindelser og fremgangsmater for fremstilling og anvendelser av dem | |
| WO2007040438A3 (fr) | Derives d'imidazo(4,5-b) pyridine utilises comme inhibiteurs de la glycogene synthase kinase 3 pour le traitement de la demence et de troubles neurodegeneratifs | |
| NO20070199L (no) | Substituerte kinazoloner som anti-kreftmidler | |
| WO2007044085A3 (fr) | Composes heteroaryle et leurs utilisations en tant qu'agents therapeutiques | |
| NO20070432L (no) | Pyrimidinureaderivater som kinaseinhibitorer | |
| NO20080408L (no) | Azaindazolforbindelser og anvendelse derav | |
| NO20075059L (no) | Nye forbindelser II 2-pyridinderivater som inhibitorer av neutrofil elastase | |
| NO20100827L (no) | Glukocorticoid-mimetica, fremgangsmater for fremstilling av dem, farmasoytiske blandinger, og anvendelser derav | |
| NO20071246L (no) | Kinazolinonderivater og deres anvendelse som B-RAF-inhibitorer. | |
| NO20072259L (no) | Heteroaryltiazoler og deres anvendelse som P13K-inhibitorer | |
| NO20073140L (no) | Pyrrolopyraziner og pyralopyraziner som er nyttige som inhibitorer av proteinkinaser | |
| NO20081349L (no) | Pyrrolopyrimidinderivater som Syk-inhibitorer | |
| NO20052802L (no) | Pyrrolopyrimidinderivativer | |
| NO20072784L (no) | Pyridenkarboksamidderivater for anvendelse som anticancer midler | |
| WO2008045664A3 (fr) | Inhibiteurs hétérocycliques de pde4 | |
| WO2005049581A8 (fr) | Derives de pyridazine-3(2h)-ones et utilisation en tant qu'inhibiteurs de pde4 | |
| SG170101A1 (en) | 2-pyrazinone derivatives for the treatment of disease or condition in which inhibition of neutrophil elastase activity is beneficial. | |
| WO2002083667A3 (fr) | Inhibiteurs de c-jun n-terminal kinases (jnk) et d'autres proteines kinases |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |