NO20063276L - Anvendelse av rotigotin til behandling eller forhindring av dopaminergt nevrontap - Google Patents
Anvendelse av rotigotin til behandling eller forhindring av dopaminergt nevrontapInfo
- Publication number
- NO20063276L NO20063276L NO20063276A NO20063276A NO20063276L NO 20063276 L NO20063276 L NO 20063276L NO 20063276 A NO20063276 A NO 20063276A NO 20063276 A NO20063276 A NO 20063276A NO 20063276 L NO20063276 L NO 20063276L
- Authority
- NO
- Norway
- Prior art keywords
- rotigotine
- treatment
- prevention
- neuronal loss
- dopaminergic neuronal
- Prior art date
Links
- KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 title abstract 3
- 229960003179 rotigotine Drugs 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 2
- 230000004771 dopaminergic neurodegeneration Effects 0.000 title 1
- 230000006378 damage Effects 0.000 abstract 2
- 210000004002 dopaminergic cell Anatomy 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
Oppfinnelsen angår anvendelsen av rotigotin eller salter derav og prolegemidler for fremstilling av et legemiddel for behandling eller forhindring av dopaminerg celledestruksjon i sykdommer som har sammenheng med økt dopaminerg celledestruksjon. Oppfinnelsen angår også anvendelsen av rotigotin som et legemiddel for å forhindre Parkinsons sykdom.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10361259A DE10361259A1 (de) | 2003-12-24 | 2003-12-24 | Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes |
| PCT/EP2004/014655 WO2005063237A1 (de) | 2003-12-24 | 2004-12-23 | Verwendung von rotigotin zur behandlung oder zur prävention des dopaminergen neuronenverlustes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20063276L true NO20063276L (no) | 2006-08-30 |
Family
ID=34706587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20063276A NO20063276L (no) | 2003-12-24 | 2006-07-14 | Anvendelse av rotigotin til behandling eller forhindring av dopaminergt nevrontap |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1696904B1 (no) |
| JP (1) | JP5032125B2 (no) |
| KR (1) | KR101296561B1 (no) |
| CN (1) | CN1897935B (no) |
| AT (1) | ATE533484T1 (no) |
| AU (1) | AU2004308648B2 (no) |
| BR (1) | BRPI0418195A (no) |
| CA (1) | CA2547645C (no) |
| DE (1) | DE10361259A1 (no) |
| DK (1) | DK1696904T3 (no) |
| EA (1) | EA014418B1 (no) |
| ES (1) | ES2376881T3 (no) |
| IL (1) | IL175891A0 (no) |
| IS (1) | IS8493A (no) |
| NO (1) | NO20063276L (no) |
| NZ (1) | NZ547841A (no) |
| PL (1) | PL1696904T3 (no) |
| UA (1) | UA85858C2 (no) |
| WO (1) | WO2005063237A1 (no) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10361258A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| DE102004014841B4 (de) * | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| JP5282228B2 (ja) * | 2005-10-21 | 2013-09-04 | 株式会社ファンケル | アトピー性皮膚炎マーカーとその利用技術 |
| CN101147739B (zh) | 2007-07-06 | 2010-12-08 | 北京康倍得医药技术开发有限公司 | 含罗替戈汀的组合物及其制药用途以及含该组合物的透皮贴剂 |
| MY165575A (en) | 2007-11-28 | 2018-04-05 | Ucb Pharma Gmbh | Polymorphic form of rotigotine |
| EP2201941A1 (de) | 2008-12-29 | 2010-06-30 | UCB Pharma GmbH | Pflaster-Herstellungstechnologie |
| EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
| CN102665699A (zh) | 2009-12-22 | 2012-09-12 | 优时比制药有限公司 | 用于使非结晶形式的罗替戈汀的固体分散体稳定化的聚乙烯吡咯烷酮 |
| US8729306B2 (en) | 2010-02-05 | 2014-05-20 | Ucb Pharma Gmbh | Process for the preparation of nitrogen substituted aminotetralins derivatives |
| BR112012029944A2 (pt) | 2010-06-25 | 2019-09-24 | Ucb Pharma Gmbh | processo para preparação de derivados de aminotetralinas substituídas com nitrogênio |
| CN102379873B (zh) * | 2010-09-06 | 2013-10-30 | 四川大学华西医院 | 一种急性全身性猴帕金森病模型及其药物筛选方法 |
| EP2559435A1 (en) | 2011-08-19 | 2013-02-20 | UCB Pharma GmbH | Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke |
| WO2014037832A2 (en) | 2012-09-06 | 2014-03-13 | Mahesh Kandula | Compositions and methods for the treatment of epilepsy and neurological diseases |
| WO2013075823A1 (en) | 2011-11-22 | 2013-05-30 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermal therapeutic system comprising rotigotine and crystallization inhibitor |
| DE102012013439A1 (de) | 2012-07-03 | 2014-01-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor |
| DE102012013421A1 (de) | 2012-07-03 | 2014-01-09 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TTS) mit Rotigotin |
| CN104350041A (zh) | 2012-05-07 | 2015-02-11 | 塞利克斯比奥私人有限公司 | 用于治疗神经系统疾病的组合物和方法 |
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| WO2013175347A2 (en) | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of respiratory disorders |
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| AU2013311349A1 (en) | 2012-09-08 | 2014-11-27 | Cellixbio Private Limited | Compositions and methods for treatment of inflammation and lipid disorders |
| TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
| US9333187B1 (en) | 2013-05-15 | 2016-05-10 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory bowel disease |
| AU2014276346A1 (en) | 2013-06-04 | 2015-12-24 | Cellixbio Private Limited | Compositions and methods for the treatment of diabetes and pre-diabetes |
| CA2916183C (en) | 2013-07-03 | 2022-03-29 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system with electronic component |
| US9096537B1 (en) | 2014-12-31 | 2015-08-04 | Mahesh Kandula | Compositions and methods for the treatment of mucositis |
| JP6573913B2 (ja) * | 2014-05-20 | 2019-09-11 | エルテーエス ローマン テラピー−ジステーメ アーゲー | ロチゴチンを含む経皮送達システム |
| CA2948219C (en) | 2014-05-20 | 2023-04-04 | Lts Lohmann Therapie-Systeme Ag | Method for adjusting the release of active agent in a transdermal delivery system |
| US11752110B2 (en) | 2014-05-20 | 2023-09-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
| EP3240779B1 (en) | 2014-09-26 | 2020-10-28 | Cellixbio Private Limited | Compositions and methods for the treatment of epilepsy and neurological disorders |
| EP3201168B1 (en) | 2014-09-29 | 2020-03-18 | Cellix Bio Private Limited | Compounds and compositions for the treatment of multiple sclerosis |
| EP3212626B1 (en) | 2014-10-27 | 2018-11-07 | Cellix Bio Private Limited | Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis |
| US9284287B1 (en) | 2014-11-05 | 2016-03-15 | Cellix Bio Private Limited | Compositions and methods for the suppression of carbonic anhydrase activity |
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| US9321716B1 (en) | 2014-11-05 | 2016-04-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of metabolic syndrome |
| US9173877B1 (en) | 2014-11-05 | 2015-11-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of local pain |
| US9932294B2 (en) | 2014-12-01 | 2018-04-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
| US9206111B1 (en) | 2014-12-17 | 2015-12-08 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological diseases |
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| ES2855976T3 (es) * | 2016-07-21 | 2021-09-27 | Shandong luye pharmaceutical co ltd | Behenato de rotigotina y procedimiento de fabricación y aplicación del mismo |
| FI3854388T3 (fi) | 2020-01-24 | 2023-11-27 | Luye Pharma Switzerland Ag | Transdermaalinen hoitojärjestelmä, jossa on vaikuttava aine rotigotiini ja ainakin yksi ei-amiiniresistentti silikoniliima |
| CN112014193B (zh) * | 2020-07-24 | 2021-06-15 | 武汉大学中南医院 | 一种新的fj染色方法和装置 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4564628A (en) * | 1983-01-03 | 1986-01-14 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
| CO5111024A1 (es) * | 1998-12-29 | 2001-12-26 | Kimberly Clark Co | Composiciones de recubrimientos de polimero disparado por ion sobre peliculas de polimero sensibles al agua |
| SE9904723D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| EP1332363A4 (en) * | 2000-10-09 | 2007-08-29 | Kay Double | PROOF OF NEURODEGENERATIVE DISEASES |
| DK1256339T3 (da) * | 2001-05-08 | 2004-02-09 | Sanol Arznei Schwarz Gmbh | Transdermalt terapeutisk system for opnåelse af høje plasmaniveauer af rotigotin i behandlingen af Parkinsons sygdom |
| ES2203563T3 (es) * | 2001-05-08 | 2004-04-16 | Schwarz Pharma Ag | Sistema terapeutico transdermico mejorado para el tratamiento de la enfermedad de parkinson. |
| FR2828212B1 (fr) * | 2001-08-03 | 2003-10-31 | Aventis Pharma Sa | Methodes de diagnostic et de pronostic de la maladie de parkinson |
| EP1386605A1 (en) * | 2002-07-30 | 2004-02-04 | Schwarz Pharma Ag | Improved transdermal delivery system for the administration of rotigotine |
| DE10361258A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| DE102004014841B4 (de) * | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
-
2003
- 2003-12-24 DE DE10361259A patent/DE10361259A1/de not_active Withdrawn
-
2004
- 2004-12-23 AT AT04804249T patent/ATE533484T1/de active
- 2004-12-23 DK DK04804249.3T patent/DK1696904T3/da active
- 2004-12-23 AU AU2004308648A patent/AU2004308648B2/en not_active Ceased
- 2004-12-23 CN CN2004800386660A patent/CN1897935B/zh not_active Expired - Fee Related
- 2004-12-23 BR BRPI0418195-6A patent/BRPI0418195A/pt not_active IP Right Cessation
- 2004-12-23 NZ NZ547841A patent/NZ547841A/en not_active IP Right Cessation
- 2004-12-23 UA UAA200606332A patent/UA85858C2/uk unknown
- 2004-12-23 PL PL04804249T patent/PL1696904T3/pl unknown
- 2004-12-23 EA EA200601227A patent/EA014418B1/ru not_active IP Right Cessation
- 2004-12-23 JP JP2006546071A patent/JP5032125B2/ja not_active Expired - Fee Related
- 2004-12-23 EP EP04804249A patent/EP1696904B1/de not_active Revoked
- 2004-12-23 KR KR1020067012204A patent/KR101296561B1/ko not_active Expired - Fee Related
- 2004-12-23 ES ES04804249T patent/ES2376881T3/es not_active Expired - Lifetime
- 2004-12-23 WO PCT/EP2004/014655 patent/WO2005063237A1/de not_active Ceased
- 2004-12-23 CA CA2547645A patent/CA2547645C/en not_active Expired - Fee Related
-
2006
- 2006-05-24 IL IL175891A patent/IL175891A0/en unknown
- 2006-05-31 IS IS8493A patent/IS8493A/is unknown
- 2006-07-14 NO NO20063276A patent/NO20063276L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IS8493A (is) | 2006-05-31 |
| CN1897935A (zh) | 2007-01-17 |
| DE10361259A1 (de) | 2005-07-28 |
| PL1696904T3 (pl) | 2012-04-30 |
| JP5032125B2 (ja) | 2012-09-26 |
| CN1897935B (zh) | 2010-05-26 |
| IL175891A0 (en) | 2006-10-05 |
| EA200601227A1 (ru) | 2006-12-29 |
| CA2547645A1 (en) | 2005-07-14 |
| CA2547645C (en) | 2013-07-16 |
| AU2004308648A1 (en) | 2005-07-14 |
| EP1696904B1 (de) | 2011-11-16 |
| WO2005063237A1 (de) | 2005-07-14 |
| JP2007516996A (ja) | 2007-06-28 |
| KR101296561B1 (ko) | 2013-08-13 |
| HK1094538A1 (en) | 2007-04-04 |
| BRPI0418195A (pt) | 2007-06-19 |
| EA014418B1 (ru) | 2010-12-30 |
| AU2004308648B2 (en) | 2010-12-16 |
| EP1696904A1 (de) | 2006-09-06 |
| UA85858C2 (uk) | 2009-03-10 |
| ATE533484T1 (de) | 2011-12-15 |
| ES2376881T3 (es) | 2012-03-20 |
| KR20060109952A (ko) | 2006-10-23 |
| DK1696904T3 (da) | 2012-02-13 |
| NZ547841A (en) | 2011-02-25 |
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