[go: up one dir, main page]

NO20062616L - Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder - Google Patents

Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder

Info

Publication number
NO20062616L
NO20062616L NO20062616A NO20062616A NO20062616L NO 20062616 L NO20062616 L NO 20062616L NO 20062616 A NO20062616 A NO 20062616A NO 20062616 A NO20062616 A NO 20062616A NO 20062616 L NO20062616 L NO 20062616L
Authority
NO
Norway
Prior art keywords
preparation
treatment methods
new compounds
compositions
matching compositions
Prior art date
Application number
NO20062616A
Other languages
English (en)
Inventor
Orco Philip C Dell
Ann Marie Diederich
Qiaogang Su
Jeffery Lee Wood
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NO20062616L publication Critical patent/NO20062616L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Det beskrives en ny, krystallinsk form av topotecanmonohydrokloridpentahydrat. Forbindelsen er et pentahydrat av 10-[(dimetylamino)metyl]-4-etyl-4,9-dihydroksy-1H-pyranol[3',4': 6,7]indolizino[1,2-b]kinolin-3,14(4H,12H)dionmonohydroklorid. Videre beskrives farmasøytiske preparater, fremstillingsmetoder og/eller bruk derav for å behandle antivirale og/eller cancerrelaterte sykdommer.
NO20062616A 2003-11-12 2006-06-07 Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder NO20062616L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51916003P 2003-11-12 2003-11-12
US52457403P 2003-11-24 2003-11-24
PCT/US2004/037626 WO2005046608A2 (en) 2003-11-12 2004-11-12 Novel compound, corresponding compositions, preparation and/or treatment methods

Publications (1)

Publication Number Publication Date
NO20062616L true NO20062616L (no) 2006-07-12

Family

ID=34594951

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062616A NO20062616L (no) 2003-11-12 2006-06-07 Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder

Country Status (16)

Country Link
US (2) US7754733B2 (no)
EP (1) EP1689400A4 (no)
JP (1) JP2007510751A (no)
KR (1) KR20060122847A (no)
CN (1) CN1913897B (no)
AR (1) AR046579A1 (no)
AU (1) AU2004289318B2 (no)
BR (1) BRPI0416366A (no)
CA (1) CA2545876A1 (no)
IL (1) IL175369A (no)
IS (1) IS8491A (no)
MA (1) MA28179A1 (no)
NO (1) NO20062616L (no)
RU (1) RU2352572C2 (no)
TW (1) TWI333492B (no)
WO (1) WO2005046608A2 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI333492B (en) * 2003-11-12 2010-11-21 Smithkline Beecham Cork Ltd Crystalline topotecan hydrochloride product and preparation thereof
KR20080068052A (ko) * 2005-10-10 2008-07-22 씨아이피엘에이 엘티디. 신규의 결정형
US7547785B2 (en) * 2005-12-26 2009-06-16 Dr. Reddy's Laboratories Limited Process for preparing topotecan
US7977483B2 (en) 2007-04-11 2011-07-12 Scinopharm Taiwan, Ltd. Process for making topotecan
WO2008130534A1 (en) * 2007-04-19 2008-10-30 Scinopharm Taiwan Ltd. Crystalline forms of topotecan hydrochloride and processes for making the same
US7572803B2 (en) * 2007-10-25 2009-08-11 The Christus Stehlin Foundation For Cancer Research Hydrated crystalline esters of camptothecin
ITMI20072268A1 (it) 2007-12-04 2009-06-05 Antibioticos Spa Polimorfi cristallini di topotecan cloridrato con elevato grado di purezza e metodi per la loro preparazione
WO2023220641A2 (en) 2022-05-11 2023-11-16 Juno Therapeutics, Inc. Methods and uses related to t cell therapy and production of same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004758A (en) * 1987-12-01 1991-04-02 Smithkline Beecham Corporation Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
HUT70024A (en) * 1990-09-28 1995-09-28 Smithkline Beecham Corp Process for preparing water soluble camptothecin analogs
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2790261B1 (fr) * 1999-02-26 2004-09-10 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
IT1282673B1 (it) * 1996-02-23 1998-03-31 Ist Naz Stud Cura Dei Tumori Derivati della camptotecina e loro uso come agenti antitumorali
PT847397E (pt) * 1996-12-19 2003-01-31 Reddys Lab Ltd Dr Analogos de anel c soluveis em agua de 20(s)-camptotecinac
AR013261A1 (es) * 1997-08-01 2000-12-13 Smithkline Beecham Corp Formulaciones farmaceuticas para analogos de camptotecina en capsula de gelatina
US7071203B2 (en) * 2001-09-25 2006-07-04 Dr. Reddy's Laboratories Limited Pharmaceutically acceptable salts of 20(s)-camptothecins
US6492379B1 (en) * 2002-02-21 2002-12-10 Super Gen, Inc. Compositions and formulations of 9-nitrocamptothecin polymorphs and methods of use therefor
TWI333492B (en) * 2003-11-12 2010-11-21 Smithkline Beecham Cork Ltd Crystalline topotecan hydrochloride product and preparation thereof
KR20080068052A (ko) 2005-10-10 2008-07-22 씨아이피엘에이 엘티디. 신규의 결정형
US7547785B2 (en) 2005-12-26 2009-06-16 Dr. Reddy's Laboratories Limited Process for preparing topotecan
WO2008130534A1 (en) 2007-04-19 2008-10-30 Scinopharm Taiwan Ltd. Crystalline forms of topotecan hydrochloride and processes for making the same
ITMI20072268A1 (it) 2007-12-04 2009-06-05 Antibioticos Spa Polimorfi cristallini di topotecan cloridrato con elevato grado di purezza e metodi per la loro preparazione

Also Published As

Publication number Publication date
CN1913897A (zh) 2007-02-14
WO2005046608B1 (en) 2005-12-29
US20100210677A1 (en) 2010-08-19
IL175369A (en) 2012-03-29
KR20060122847A (ko) 2006-11-30
CA2545876A1 (en) 2005-05-26
TWI333492B (en) 2010-11-21
US8158645B2 (en) 2012-04-17
IS8491A (is) 2006-05-30
IL175369A0 (en) 2008-04-13
US7754733B2 (en) 2010-07-13
WO2005046608A2 (en) 2005-05-26
BRPI0416366A (pt) 2007-03-13
AU2004289318A1 (en) 2005-05-26
AU2004289318B2 (en) 2010-04-29
CN1913897B (zh) 2010-08-11
AR046579A1 (es) 2005-12-14
US20070117832A1 (en) 2007-05-24
WO2005046608A3 (en) 2005-11-03
MA28179A1 (fr) 2006-09-01
RU2352572C2 (ru) 2009-04-20
TW200530250A (en) 2005-09-16
EP1689400A4 (en) 2006-12-27
JP2007510751A (ja) 2007-04-26
EP1689400A2 (en) 2006-08-16
RU2006120422A (ru) 2007-12-27

Similar Documents

Publication Publication Date Title
ATE370138T1 (de) Neue imidazopyridine und ihre verwendung
ATE437872T1 (de) Proteinkinaseinhibitoren
ATE365742T1 (de) 4-aminothieno(2,3-d) pyrimidin -6-carbonitril- derivative zur verwendung als pde7 inhibitoren
WO2001064639A3 (en) Pde iv inhibiting amides, compositions and pharmaceutical use
NO20055421L (no) Kinolinderivater som fosfodiestrase-inhibitorer
HU0102272D0 (en) Compositions and methods for stimulating gastrointestinal motilis
GB0112348D0 (en) Compounds
NO20051263L (no) Ny anvendelse av benzotiazolderivater
EA200600811A1 (ru) НОВЫЕ ПРОИЗВОДНЫЕ ТЕТРАГИДРОСПИРО {ПИПЕРИДИН-2,7'-ПИРРОЛО [3,2-b]ПИРИДИНА} И НОВЫЕ ПРОИЗВОДНЫЕ ИНДОЛА, ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ РАССТРОЙСТВ, СВЯЗАННЫХ С 5-HT-РЕЦЕПТОРОМ
NO20070837L (no) Pyrido-pyrido pyrimidinderivater, fremstilling derav samt terapeutisk anvendelse for behandling av cancer.
WO2000068198A3 (en) Heterosubstituted pyridine derivatives as pde 4 inhibitors
CY1109366T1 (el) Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης
IL156827A (en) Derivatives of 2-mercapto- [3,1] thiazolo [4,5 [b- pyridine and pharmaceutical preparations containing them for the treatment of cardiovascular disease
MY133527A (en) Isoquinoline derivatives
AP1564A (en) Piperazinyl sulfonic acid derivatives, their pharmaceutical compositions and methods of use.
ECSP055809A (es) Inhibidores 4-oxo-1-(3-fenil sustituido)-1,4-dihidro-1,8-naftiridina-3-carboxamida de la fosfodiesterasa-4
WO2000064874A3 (en) Heterosubstituted pyridine derivatives as pde 4 inhibitors
TW200504029A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
CA2354606A1 (en) Azabicycloalkane derivatives and therapeutic uses thereof
NO20062616L (no) Nye forbindelse, samsvarende sammensetninger, fremstilling og/eller behandlingsmetoder
TW200504030A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
ATE390923T1 (de) Topoisomerase-giftmittel
WO2003059911A3 (en) 4-OXO-4, 7-DIHYDROFURO[2,3-b]PYRIDINE-5-CARBOXAMIDE ANTIVIRAL AGENTS
GB0319037D0 (en) 7-Azaindole Derivatives
NO20055997L (no) Diarylmetylidenpiperidinderivater og deres anvendelse som opiodreseptoragonister

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application