NO20061978L - Imidazopyridinsubstituerte tropanderivater med CCR5-reseptorantagonist aktivitet for behandling av HIV og inflammasjon - Google Patents

Imidazopyridinsubstituerte tropanderivater med CCR5-reseptorantagonist aktivitet for behandling av HIV og inflammasjon

Info

Publication number: NO20061978L
Authority: NO; Norway
Prior art keywords: treatment; hiv; imidazopyridine; inflammation; receptor antagonist
Prior art date: 2003-10-03

Application number

NO20061978A

Other languages

English (en)

Norwegian (no)

Inventor

Paul Anthony Stupple

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-03

Filing date

2006-05-03

Publication date

2006-07-03

2003-10-03 Priority claimed from GBGB0323236.0A external-priority patent/GB0323236D0/en

2003-10-27 Priority claimed from GB0325020A external-priority patent/GB0325020D0/en

2004-08-19 Priority claimed from GB0418566A external-priority patent/GB0418566D0/en

2006-05-03 Application filed by Pfizer filed Critical Pfizer

2006-07-03 Publication of NO20061978L publication Critical patent/NO20061978L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Diabetes (AREA)
Immunology (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Obesity (AREA)
Rheumatology (AREA)
Tropical Medicine & Parasitology (AREA)
Pulmonology (AREA)
Child & Adolescent Psychology (AREA)
Neurology (AREA)
Biotechnology (AREA)
AIDS & HIV (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Biomedical Technology (AREA)
Transplantation (AREA)

NO20061978A 2003-10-03 2006-05-03 Imidazopyridinsubstituerte tropanderivater med CCR5-reseptorantagonist aktivitet for behandling av HIV og inflammasjon NO20061978L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB0323236.0A GB0323236D0 (en)	2003-10-03	2003-10-03	Chemical compounds
GB0325020A GB0325020D0 (en)	2003-10-27	2003-10-27	Chemical compounds
GB0418566A GB0418566D0 (en)	2004-08-19	2004-08-19	Tropane derivatives
PCT/IB2004/003153 WO2005033107A1 (en)	2003-10-03	2004-09-28	Imidazopyridine substituted tropane derivatives with ccr5 receptor antagonist activity for the treatment of hiv and inflammation

Publications (1)

Publication Number	Publication Date
NO20061978L true NO20061978L (no)	2006-07-03

Family

ID=34426592

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20061978A NO20061978L (no)	2003-10-03	2006-05-03	Imidazopyridinsubstituerte tropanderivater med CCR5-reseptorantagonist aktivitet for behandling av HIV og inflammasjon

Country Status (35)

Country	Link
US (2)	US7309790B2 (es)
EP (1)	EP1682545B1 (es)
JP (1)	JP4874107B2 (es)
KR (1)	KR100777885B1 (es)
AP (1)	AP2174A (es)
AR (1)	AR045856A1 (es)
AT (1)	ATE380813T1 (es)
AU (1)	AU2004278158B2 (es)
BR (1)	BRPI0414862A (es)
CA (1)	CA2540834C (es)
CY (1)	CY1107281T1 (es)
DE (1)	DE602004010708T2 (es)
DK (1)	DK1682545T3 (es)
EA (1)	EA009941B1 (es)
EC (1)	ECSP066475A (es)
ES (1)	ES2295924T3 (es)
GE (1)	GEP20084417B (es)
HN (1)	HN2004000383A (es)
HR (1)	HRP20080052T3 (es)
IL (1)	IL174208A0 (es)
MA (1)	MA28080A1 (es)
MX (1)	MXPA06003749A (es)
MY (1)	MY137609A (es)
NO (1)	NO20061978L (es)
NZ (1)	NZ545837A (es)
OA (1)	OA13266A (es)
PA (1)	PA8614301A1 (es)
PE (1)	PE20050961A1 (es)
PL (1)	PL1682545T3 (es)
PT (1)	PT1682545E (es)
RS (1)	RS20060198A (es)
SI (1)	SI1682545T1 (es)
TW (1)	TWI280244B (es)
UY (1)	UY28546A1 (es)
WO (1)	WO2005033107A1 (es)

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TWI329105B (en)	2002-02-01	2010-08-21	Rigel Pharmaceuticals Inc	2,4-pyrimidinediamine compounds and their uses
HRP20130602T1 (en)	2003-07-30	2013-07-31	Rigel Pharmaceuticals, Inc.	2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
CA2608367C (en)	2005-06-08	2014-08-19	Rigel Pharmaceuticals, Inc.	Compositions and methods for inhibition of the jak pathway
US20070203161A1 (en)	2006-02-24	2007-08-30	Rigel Pharmaceuticals, Inc.	Compositions and methods for inhibition of the jak pathway
ES2622493T3 (es)	2006-02-24	2017-07-06	Rigel Pharmaceuticals, Inc.	Composiciones y métodos para la inhibición de la ruta de JAK
EP2997964A1 (en)	2006-04-05	2016-03-23	OPKO Health, Inc.	Pharmaceutical formulations comprising salts of (5s,8s)-8-[{(1 r)-1-(3,5-bis-trifluoromethyl)phenyl]- ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one and their medical use
US20080108586A1 (en) *	2006-09-06	2008-05-08	Incyte Corporation	Combination therapy for human immunodeficiency virus infection
CA2673125C (en)	2006-10-19	2015-04-21	Rigel Pharmaceuticals, Inc.	Compositions and methods for inhibition of the jak pathway
WO2008085302A1 (en) *	2006-12-20	2008-07-17	Merck & Co., Inc.	Imidazopyridine analogs as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases
PE20081891A1 (es) *	2007-03-22	2008-12-27	Opko Health Inc	Formulaciones de comprimidos que contienen sales de 8-[{1-(3,5-bis-(trifluorometil)fenil)-etoxi}-metil]-8-fenil-1,7-diaza-spiro[4.5]decan-2-ona y comprimidos elaborados a partir de estas
WO2009055077A1 (en) *	2007-10-25	2009-04-30	Exelixis, Inc.	Tropane compounds
AU2009214440B2 (en)	2008-02-15	2014-09-25	Rigel Pharmaceuticals, Inc.	Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
US8138339B2 (en)	2008-04-16	2012-03-20	Portola Pharmaceuticals, Inc.	Inhibitors of protein kinases
AU2009244897B2 (en)	2008-04-16	2014-11-13	Alexion Pharmaceuticals, Inc.	2, 6-diamino- pyrimidin- 5-yl-carboxamides as syk or JAK kinases inhibitors
WO2009131687A2 (en)	2008-04-22	2009-10-29	Portola Pharmaceuticals, Inc.	Inhibitors of protein kinases
JP2010043063A (ja)	2008-05-09	2010-02-25	Agency For Science Technology & Research	川崎病の診断及び治療
AU2010282483B2 (en)	2009-08-14	2014-09-04	Opko Health, Inc.	Intravenous formulations of neurokinin-1 antagonists
MX2012011415A (es)	2010-04-02	2013-02-26	Phivco 1 Llc	Terapia de combinacion que comprende un antagonista de ccr5, un inhibidor de proteasa de vih-1, y un potenciador farmacocinetico.
EP2635557A2 (en)	2010-11-01	2013-09-11	Portola Pharmaceuticals, Inc.	Nicotinamides as jak kinase modulators
US20140271680A1 (en)	2011-08-12	2014-09-18	Universite Paris-Est Creteil Val De Marne	Methods and pharmaceutical compositions for treatment of pulmonary hypertension
SG10201601352UA (en)	2011-11-23	2016-03-30	Portola Pharm Inc	Pyrazine kinase inhibitors
EP2903970A4 (en)	2012-10-08	2016-11-30	Portola Pharm Inc	SUBSTITUTED PYRIMIDINYL KINASE INHIBITORS
MX382629B (es) *	2013-09-25	2025-03-13	SpecGx LLC	Preparación de 3-fluoropropil-nor-beta-cit radioyodado.
GB201321748D0 (en)	2013-12-09	2014-01-22	Ucb Pharma Sa	Therapeutic agents
US11629196B2 (en)	2020-04-27	2023-04-18	Incelldx, Inc.	Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions
WO2023192361A1 (en) *	2022-03-31	2023-10-05	Incelldx, Inc.	Methods of treating a subject for fibromyalgia and compositions for use in the same
WO2023192360A1 (en) *	2022-03-31	2023-10-05	Incelldx, Inc.	Methods of treating a subject for post-treatment lyme disease (ptld) and compositions for use in the same

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SK281813B6 (sk)	1996-02-22	2001-08-06	Neurosearch A/S	Tropánové deriváty, spôsob ich prípravy, použitie a farmaceutická kompozícia s ich obsahom
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IL152531A0 (en) *	2000-05-26	2003-05-29	Pfizer	Tropane derivatives useful in therapy
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2004
- 2004-09-28 US US10/953,136 patent/US7309790B2/en not_active Expired - Fee Related
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- 2004-09-28 ES ES04769496T patent/ES2295924T3/es not_active Expired - Lifetime
- 2004-09-28 AU AU2004278158A patent/AU2004278158B2/en not_active Ceased
- 2004-09-28 WO PCT/IB2004/003153 patent/WO2005033107A1/en not_active Ceased
- 2004-09-28 PT PT04769496T patent/PT1682545E/pt unknown
- 2004-09-28 MX MXPA06003749A patent/MXPA06003749A/es active IP Right Grant
- 2004-09-28 GE GEAP20049330A patent/GEP20084417B/en unknown
- 2004-09-28 JP JP2006530737A patent/JP4874107B2/ja not_active Expired - Fee Related
- 2004-09-28 OA OA1200600114A patent/OA13266A/en unknown
- 2004-09-28 SI SI200430564T patent/SI1682545T1/sl unknown
- 2004-09-28 PL PL04769496T patent/PL1682545T3/pl unknown
- 2004-09-28 BR BRPI0414862-2A patent/BRPI0414862A/pt not_active IP Right Cessation
- 2004-09-28 AT AT04769496T patent/ATE380813T1/de active
- 2004-09-28 EA EA200600480A patent/EA009941B1/ru not_active IP Right Cessation
- 2004-09-28 HR HR20080052T patent/HRP20080052T3/xx unknown
- 2004-09-28 RS YUP-2006/0198A patent/RS20060198A/sr unknown
- 2004-09-28 DE DE602004010708T patent/DE602004010708T2/de not_active Expired - Lifetime
- 2004-09-28 KR KR1020067006293A patent/KR100777885B1/ko not_active Expired - Fee Related
- 2004-09-28 DK DK04769496T patent/DK1682545T3/da active
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2006
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- 2006-04-03 EC EC2006006475A patent/ECSP066475A/es unknown
- 2006-04-03 MA MA28906A patent/MA28080A1/fr unknown
- 2006-05-03 NO NO20061978A patent/NO20061978L/no not_active Application Discontinuation
2007
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Also Published As

Publication number	Publication date
ATE380813T1 (de)	2007-12-15
AR045856A1 (es)	2005-11-16
NZ545837A (en)	2009-12-24
AP2006003580A0 (en)	2006-04-30
TW200519112A (en)	2005-06-16
UY28546A1 (es)	2005-05-31
KR100777885B1 (ko)	2007-11-28
BRPI0414862A (pt)	2006-11-28
RS20060198A (sr)	2008-09-29
GEP20084417B (en)	2008-07-10
MXPA06003749A (es)	2006-06-14
PA8614301A1 (es)	2005-05-10
CA2540834A1 (en)	2005-04-14
MA28080A1 (fr)	2006-08-01
US20050131011A1 (en)	2005-06-16
EP1682545A1 (en)	2006-07-26
DE602004010708T2 (de)	2008-12-04
HRP20080052T3 (hr)	2008-02-29
KR20060070571A (ko)	2006-06-23
WO2005033107A1 (en)	2005-04-14
TWI280244B (en)	2007-05-01
CA2540834C (en)	2010-06-22
SI1682545T1 (sl)	2008-04-30
DK1682545T3 (da)	2008-03-17
PT1682545E (pt)	2008-02-11
ES2295924T3 (es)	2008-04-16
PL1682545T3 (pl)	2008-04-30
AU2004278158B2 (en)	2009-08-13
US7790740B2 (en)	2010-09-07
US20080045563A1 (en)	2008-02-21
IL174208A0 (en)	2006-08-01
ECSP066475A (es)	2006-10-10
EA009941B1 (ru)	2008-04-28
DE602004010708D1 (de)	2008-01-24
EA200600480A1 (ru)	2006-08-25
HN2004000383A (es)	2008-10-14
PE20050961A1 (es)	2005-11-29
OA13266A (en)	2007-01-31
JP2007507483A (ja)	2007-03-29
EP1682545B1 (en)	2007-12-12
AU2004278158A1 (en)	2005-04-14
CY1107281T1 (el)	2012-11-21
US7309790B2 (en)	2007-12-18
MY137609A (en)	2009-02-27
JP4874107B2 (ja)	2012-02-15
AP2174A (en)	2010-11-20

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