NO20060279L - Thienopyridonderivater som kinaseinhibitorer - Google Patents
Thienopyridonderivater som kinaseinhibitorerInfo
- Publication number
- NO20060279L NO20060279L NO20060279A NO20060279A NO20060279L NO 20060279 L NO20060279 L NO 20060279L NO 20060279 A NO20060279 A NO 20060279A NO 20060279 A NO20060279 A NO 20060279A NO 20060279 L NO20060279 L NO 20060279L
- Authority
- NO
- Norway
- Prior art keywords
- kinase inhibitors
- thienopyridone derivatives
- derivatives
- thienopyridone
- inhibitors
- Prior art date
Links
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- MQJNETSYXIIIKE-UHFFFAOYSA-N 7h-thieno[2,3-b]pyridin-6-one Chemical group N1C(=O)C=CC2=C1SC=C2 MQJNETSYXIIIKE-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 102000002574 p38 Mitogen-Activated Protein Kinases Human genes 0.000 abstract 1
- 108010068338 p38 Mitogen-Activated Protein Kinases Proteins 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0314492A GB0314492D0 (en) | 2003-06-20 | 2003-06-20 | Chemical compounds |
| GB0329485A GB0329485D0 (en) | 2003-12-19 | 2003-12-19 | Chemical compounds |
| PCT/GB2004/002621 WO2004113347A1 (fr) | 2003-06-20 | 2004-06-18 | Derives de thienopyridone en tant qu'inhibiteurs de kinase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20060279L true NO20060279L (no) | 2006-03-20 |
Family
ID=33542685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20060279A NO20060279L (no) | 2003-06-20 | 2006-01-19 | Thienopyridonderivater som kinaseinhibitorer |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7521460B2 (fr) |
| EP (1) | EP1641804A1 (fr) |
| JP (1) | JP2007516161A (fr) |
| KR (1) | KR20060021905A (fr) |
| AU (1) | AU2004249495A1 (fr) |
| BR (1) | BRPI0410653A (fr) |
| CA (1) | CA2528602A1 (fr) |
| EA (1) | EA010297B1 (fr) |
| IL (1) | IL172132A0 (fr) |
| MX (1) | MXPA05013227A (fr) |
| NO (1) | NO20060279L (fr) |
| WO (1) | WO2004113347A1 (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0214268D0 (en) * | 2002-06-20 | 2002-07-31 | Celltech R&D Ltd | Chemical compounds |
| GB0218800D0 (en) * | 2002-08-13 | 2002-09-18 | Celltech R&D Ltd | Chemical compounds |
| CA2528603A1 (fr) * | 2003-06-20 | 2004-12-29 | Celltech R & D Limited | Derives de thienopyridone en tant qu'inhibiteurs de kinase |
| US7795256B2 (en) * | 2003-10-24 | 2010-09-14 | Ucb Pharma S.A. | Thieno-pyridinone derivatives as kinase inhibitors |
| PT1928454E (pt) | 2005-05-10 | 2014-12-04 | Intermune Inc | Derivativos da piridona para modulação do sistema de proteína quinase ativada pelo stress |
| EP1934174B1 (fr) * | 2005-10-07 | 2011-04-06 | Exelixis, Inc. | Azetidines en tant qu'inhibiteurs de mek et leur utilisation pour le traitement des maladies proliferatives |
| EP2426134A3 (fr) * | 2005-11-23 | 2012-07-04 | Intermune, Inc. | Méthode de modulation d'un système de protéine kinase activée par le stress |
| GB0601962D0 (en) | 2006-01-31 | 2006-03-15 | Ucb Sa | Therapeutic agents |
| EA200802118A1 (ru) * | 2006-04-07 | 2009-04-28 | Девелоджен Ациенгезельшафт | Обладающие ингибирующей активностью в отношении mnk1/mnk2 тиенопиримидины, предназначенные для применения в фармацевтических композициях |
| EP1889847A1 (fr) | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Dérivés de pyrrolopyrimidine pour applications pharmaceutiques |
| US20100179185A1 (en) * | 2006-11-30 | 2010-07-15 | Ucb Pharma, S.A. | Novel Aminothienopyridinone Derivatives Processes for Preparing Them and Pharmaceutical Compositions Thereof |
| JP5311673B2 (ja) | 2006-12-14 | 2013-10-09 | エグゼリクシス， インコーポレイテッド | Ｍｅｋ阻害剤の使用方法 |
| WO2008124085A2 (fr) * | 2007-04-03 | 2008-10-16 | Exelixis, Inc. | Méthodes d'utilisation de combinaisons d'inhibiteurs de mek et de jak-2 |
| GB0714384D0 (en) | 2007-07-23 | 2007-09-05 | Ucb Pharma Sa | theraputic agents |
| EP2240494B1 (fr) | 2008-01-21 | 2016-03-30 | UCB Biopharma SPRL | Dérivés de thiénopyridine utilisés comme inhibiteurs de mek |
| US8304413B2 (en) | 2008-06-03 | 2012-11-06 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
| GB0811304D0 (en) | 2008-06-19 | 2008-07-30 | Ucb Pharma Sa | Therapeutic agents |
| NZ591113A (en) | 2008-08-26 | 2012-07-27 | Boehringer Ingelheim Int | Thienopyrimidine linked to phenyl or pyridine via an nh amine for pharmaceutical compositions |
| UY33241A (es) | 2010-02-26 | 2011-09-30 | Boehringer Ingelheim Int | ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?. |
| AR080328A1 (es) | 2010-02-26 | 2012-03-28 | Boehringer Ingelheim Int | Tienopirimidinas que contienen un grupo alquilo sustituido inhibidoras de quinasas mnk1 y/o mnk2, composiciones farmaceuticas que las contienen y uso de las mismas para el tratamiento de trastornos metabolicos tales como diabetes y obesidad, y trastornos hiperproliferativos, entre otros |
| EA201201191A1 (ru) | 2010-02-26 | 2013-04-30 | Бёрингер Ингельхайм Интернациональ Гмбх | 4-[циклоалкилокси(гетеро)ариламино]тиено[2,3-d]пиримидины, обладающие ингибирующей активностью по отношению к mnkl/mnk2, предназначенные для фармацевтических композиций |
| EP2598661B1 (fr) | 2010-07-26 | 2017-09-27 | Biomatrica, INC. | Compositions de stabilisation d'adn, d'arn, de protéines salivaires et d'autres échantillons biologiques lors du transport et du stockage à températures ambiantes |
| WO2012018638A2 (fr) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions de stabilisation d'adn, d'arn, de protéines dans le sang et d'autres échantillons biologiques lors du transport et du stockage à températures ambiantes |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| HRP20180670T1 (hr) | 2012-10-12 | 2018-07-13 | Exelixis Inc. | Novi postupak dobivanja spojeva namijenjenih upotrebi u liječenju raka |
| PL2922854T3 (pl) * | 2012-11-21 | 2022-07-18 | Zoetis Services Llc | Synteza spirocyklicznych pochodnych izoksazoliny |
| EP3249054A1 (fr) | 2012-12-20 | 2017-11-29 | Biomatrica, INC. | Formulations et procédés pour stabiliser des réactifs pcr |
| EP3007556B1 (fr) | 2013-06-13 | 2020-05-20 | Biomatrica, INC. | Stabilisation de cellules |
| KR102373700B1 (ko) | 2014-04-02 | 2022-03-11 | 인터뮨, 인크. | 항섬유성 피리디논 |
| EP3942931A1 (fr) | 2014-06-10 | 2022-01-26 | Biomatrica, INC. | Stabilisation de thrombocytes à des températures ambiantes |
| KR20250047404A (ko) | 2015-12-08 | 2025-04-03 | 바이오매트리카 인코포레이티드 | 적혈구 침강 속도의 감소 |
| EP3824906A1 (fr) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Formulations d'anticorps anti-tnf alpha |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6048863A (en) * | 1994-04-19 | 2000-04-11 | Takeda Chemical Industries, Ltd. | Condensed-ring thiophene derivatives and thienopyrimidine derivatives, their production and use |
| AU4429799A (en) * | 1998-06-12 | 1999-12-30 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| GB0124848D0 (en) | 2001-10-16 | 2001-12-05 | Celltech R&D Ltd | Chemical compounds |
| GB0214268D0 (en) * | 2002-06-20 | 2002-07-31 | Celltech R&D Ltd | Chemical compounds |
| GB0218800D0 (en) * | 2002-08-13 | 2002-09-18 | Celltech R&D Ltd | Chemical compounds |
| CA2528603A1 (fr) * | 2003-06-20 | 2004-12-29 | Celltech R & D Limited | Derives de thienopyridone en tant qu'inhibiteurs de kinase |
| US7795256B2 (en) * | 2003-10-24 | 2010-09-14 | Ucb Pharma S.A. | Thieno-pyridinone derivatives as kinase inhibitors |
-
2004
- 2004-06-18 JP JP2006516443A patent/JP2007516161A/ja not_active Abandoned
- 2004-06-18 BR BRPI0410653-9A patent/BRPI0410653A/pt not_active IP Right Cessation
- 2004-06-18 KR KR1020057024352A patent/KR20060021905A/ko not_active Withdrawn
- 2004-06-18 WO PCT/GB2004/002621 patent/WO2004113347A1/fr not_active Ceased
- 2004-06-18 MX MXPA05013227A patent/MXPA05013227A/es unknown
- 2004-06-18 CA CA002528602A patent/CA2528602A1/fr not_active Abandoned
- 2004-06-18 US US10/561,052 patent/US7521460B2/en not_active Expired - Fee Related
- 2004-06-18 EP EP04742976A patent/EP1641804A1/fr not_active Withdrawn
- 2004-06-18 EA EA200600064A patent/EA010297B1/ru not_active IP Right Cessation
- 2004-06-18 AU AU2004249495A patent/AU2004249495A1/en not_active Abandoned
-
2005
- 2005-11-23 IL IL172132A patent/IL172132A0/en unknown
-
2006
- 2006-01-19 NO NO20060279A patent/NO20060279L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL172132A0 (en) | 2006-04-10 |
| EA200600064A1 (ru) | 2006-08-25 |
| AU2004249495A1 (en) | 2004-12-29 |
| WO2004113347A1 (fr) | 2004-12-29 |
| KR20060021905A (ko) | 2006-03-08 |
| EP1641804A1 (fr) | 2006-04-05 |
| MXPA05013227A (es) | 2006-03-09 |
| EA010297B1 (ru) | 2008-08-29 |
| US20070099894A1 (en) | 2007-05-03 |
| BRPI0410653A (pt) | 2006-07-04 |
| CA2528602A1 (fr) | 2004-12-29 |
| JP2007516161A (ja) | 2007-06-21 |
| US7521460B2 (en) | 2009-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |