NO20052177L - Anvendelse av galantamin og dets derivater for fremstilling av legemidler - Google Patents
Anvendelse av galantamin og dets derivater for fremstilling av legemidlerInfo
- Publication number
- NO20052177L NO20052177L NO20052177A NO20052177A NO20052177L NO 20052177 L NO20052177 L NO 20052177L NO 20052177 A NO20052177 A NO 20052177A NO 20052177 A NO20052177 A NO 20052177A NO 20052177 L NO20052177 L NO 20052177L
- Authority
- NO
- Norway
- Prior art keywords
- galantamine
- manufacture
- derivatives
- drugs
- post
- Prior art date
Links
- ASUTZQLVASHGKV-JDFRZJQESA-N galanthamine Chemical compound O1C(=C23)C(OC)=CC=C2CN(C)CC[C@]23[C@@H]1C[C@@H](O)C=C2 ASUTZQLVASHGKV-JDFRZJQESA-N 0.000 title abstract 7
- 229960003980 galantamine Drugs 0.000 title abstract 3
- ASUTZQLVASHGKV-UHFFFAOYSA-N galanthamine hydrochloride Natural products O1C(=C23)C(OC)=CC=C2CN(C)CCC23C1CC(O)C=C2 ASUTZQLVASHGKV-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 206010012218 Delirium Diseases 0.000 abstract 2
- 230000002980 postoperative effect Effects 0.000 abstract 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Foreliggende oppfinnelse angår anvendelse av galantamin og kolinergisk aktive derivater derav for fremstilling av medikamenter for preventiv behandling av postoperativ delirium og/eller undersyndron post-operativ delirium. Galantamin, galantaminderivatet (4aS, 6R, 8aS)-6-hydroksy-3-metoksy- 11 -metyl-4a,5,9,10-tetrahydro-6H-benzofuro[3a, 3, 2-ef] [2]benzazepiniumbromid og analoge salter, hydrater og solvater er fordelaktig egnet for anvendelse ifølge oppfinnelsen.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT15382003 | 2003-09-29 | ||
| PCT/AT2004/000251 WO2005030332A2 (de) | 2003-09-29 | 2004-07-12 | Verwendung von galanthamin und seinen derivaten zum herstellen von arzneimitteln |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20052177D0 NO20052177D0 (no) | 2005-05-03 |
| NO20052177L true NO20052177L (no) | 2005-06-24 |
Family
ID=34382391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052177A NO20052177L (no) | 2003-09-29 | 2005-05-03 | Anvendelse av galantamin og dets derivater for fremstilling av legemidler |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060111341A1 (no) |
| EP (1) | EP1667769A2 (no) |
| CN (1) | CN1859949A (no) |
| CA (1) | CA2506282A1 (no) |
| MX (1) | MXPA05005570A (no) |
| NO (1) | NO20052177L (no) |
| WO (1) | WO2005030332A2 (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090253654A1 (en) | 2005-09-22 | 2009-10-08 | Galantos Pharma Gmbh | Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment |
| WO2008022365A2 (de) * | 2006-08-24 | 2008-02-28 | Sanochemia Ltd. | Mittel zum beeinflussen der wirkungen von organophosphorverbindungen und verwendung von galanthamin, dessen derivaten und analoga zum herstellen solcher mittel |
| WO2013160728A1 (en) | 2012-04-26 | 2013-10-31 | Alma Mater Studiorum - Universita' Di Bologna | Dual targeting compounds for the treatment of alzheimer's disease |
| CN104860955B (zh) * | 2015-04-22 | 2017-07-14 | 华东理工大学 | 加兰他敏类似物及其用途 |
| WO2017189834A1 (en) * | 2016-04-29 | 2017-11-02 | New Mexico Tech Research Foundation | Methods for treatment of resistant cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150354A (en) * | 1987-01-15 | 2000-11-21 | Bonnie Davis | Compounds for the treatment of Alzheimer's disease |
| US6407229B1 (en) * | 1994-10-21 | 2002-06-18 | Sanochemia Pharmazeutika Ag | Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2] benzazapine |
| SI0787115T1 (en) * | 1994-10-21 | 2000-04-30 | Sanochemia Pharmazeutika Ag | PROCESS FOR PRODUCING DERIVATIVES OF 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO(3a,3,2-ef)(2)BENZAZEPINE |
| GB9514821D0 (en) * | 1995-07-19 | 1995-09-20 | Sod Conseils Rech Applic | Galanthamine derivatives |
| EP1133290B1 (de) * | 1998-11-27 | 2003-03-12 | Sanochemia Pharmazeutika Aktiengesellschaft | Verwendung von acetylcholinesterase-inhibitoren zur behandlung von delirien |
-
2004
- 2004-07-12 WO PCT/AT2004/000251 patent/WO2005030332A2/de not_active Ceased
- 2004-07-12 US US10/537,568 patent/US20060111341A1/en not_active Abandoned
- 2004-07-12 CA CA002506282A patent/CA2506282A1/en not_active Abandoned
- 2004-07-12 MX MXPA05005570A patent/MXPA05005570A/es not_active Application Discontinuation
- 2004-07-12 EP EP04737381A patent/EP1667769A2/de not_active Withdrawn
- 2004-09-09 CN CNA2004800283471A patent/CN1859949A/zh active Pending
-
2005
- 2005-05-03 NO NO20052177A patent/NO20052177L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2506282A1 (en) | 2005-04-07 |
| CN1859949A (zh) | 2006-11-08 |
| NO20052177D0 (no) | 2005-05-03 |
| WO2005030332A3 (de) | 2005-06-02 |
| US20060111341A1 (en) | 2006-05-25 |
| WO2005030332A2 (de) | 2005-04-07 |
| MXPA05005570A (es) | 2005-10-18 |
| EP1667769A2 (de) | 2006-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |