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NO20051566L - PGD2 reseptor antagonister for behandling av inflammatoriske sykdommer - Google Patents

PGD2 reseptor antagonister for behandling av inflammatoriske sykdommer

Info

Publication number
NO20051566L
NO20051566L NO20051566A NO20051566A NO20051566L NO 20051566 L NO20051566 L NO 20051566L NO 20051566 A NO20051566 A NO 20051566A NO 20051566 A NO20051566 A NO 20051566A NO 20051566 L NO20051566 L NO 20051566L
Authority
NO
Norway
Prior art keywords
treatment
receptor antagonists
inflammatory diseases
pgd2 receptor
compounds
Prior art date
Application number
NO20051566A
Other languages
English (en)
Inventor
Kenneth G Carson
Shomir Ghosh
Amy M Elder
Kevin Sprott
Sean Harrison
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of NO20051566L publication Critical patent/NO20051566L/no

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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Abstract

Beskrevet her er forbindelser representert ved Strukturformel (I) hvor variablene er definert her. Også beskrevet er anvendelse av slike forbindelser for å hemme G-protein-koblet reseptor referert til som kjemotiltrekkende reseptor-homolog-molekyl uttrykt på Th2 ("CRTH2") for behandling av inflammatoriske lidelser.
NO20051566A 2002-10-04 2005-03-23 PGD2 reseptor antagonister for behandling av inflammatoriske sykdommer NO20051566L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41650102P 2002-10-04 2002-10-04
PCT/US2003/031542 WO2004032848A2 (en) 2002-10-04 2003-10-03 Pgd2 receptor antagonists for the treatment of inflammatory diseases

Publications (1)

Publication Number Publication Date
NO20051566L true NO20051566L (no) 2005-06-15

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BR0315041A (pt) 2005-08-16
US20040082609A1 (en) 2004-04-29
JP2006124396A (ja) 2006-05-18
CN100363348C (zh) 2008-01-23
AU2003277285A1 (en) 2004-05-04
EP1556047A2 (en) 2005-07-27
KR20050055747A (ko) 2005-06-13
EP1556047A4 (en) 2009-09-30
EA200500536A1 (ru) 2005-10-27
WO2004032848A3 (en) 2004-07-15
CA2500582A1 (en) 2004-04-22
US7211672B2 (en) 2007-05-01
EA011385B1 (ru) 2009-02-27
ZA200502692B (en) 2006-11-29
JP2006508077A (ja) 2006-03-09
PL376156A1 (en) 2005-12-27
AU2003277285B2 (en) 2007-12-13
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US20060106061A1 (en) 2006-05-18

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