NO20040653L - Nytt glykolipid og medisin for autoimmunsykdom inneholdende det samme som aktiv ingrediens. - Google Patents
Nytt glykolipid og medisin for autoimmunsykdom inneholdende det samme som aktiv ingrediens.Info
- Publication number
- NO20040653L NO20040653L NO20040653A NO20040653A NO20040653L NO 20040653 L NO20040653 L NO 20040653L NO 20040653 A NO20040653 A NO 20040653A NO 20040653 A NO20040653 A NO 20040653A NO 20040653 L NO20040653 L NO 20040653L
- Authority
- NO
- Norway
- Prior art keywords
- new
- active ingredient
- same
- autoimmune disease
- gen
- Prior art date
Links
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 title abstract 3
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 229930186217 Glycolipid Natural products 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 208000030767 Autoimmune encephalitis Diseases 0.000 abstract 1
- 238000011746 C57BL/6J (JAX™ mouse strain) Methods 0.000 abstract 1
- 230000002456 anti-arthritic effect Effects 0.000 abstract 1
- 230000003178 anti-diabetic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000002682 anti-psoriatic effect Effects 0.000 abstract 1
- 230000003356 anti-rheumatic effect Effects 0.000 abstract 1
- 239000003472 antidiabetic agent Substances 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001553 hepatotropic effect Effects 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
- YGOYMNMFBVUFOH-UHFFFAOYSA-N nonane-1,1,4-triol Chemical compound CCCCCC(O)CCC(O)O YGOYMNMFBVUFOH-UHFFFAOYSA-N 0.000 abstract 1
- 239000012873 virucide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001247055 | 2001-08-16 | ||
| PCT/JP2002/008280 WO2003016326A1 (fr) | 2001-08-16 | 2002-08-14 | Glycolipide et agent therapeutique pour maladies auto-immunes le contenant en tant qu'ingredient actif |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20040653L true NO20040653L (no) | 2004-05-07 |
| NO326398B1 NO326398B1 (no) | 2008-11-24 |
Family
ID=19076468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20040653A NO326398B1 (no) | 2001-08-16 | 2004-02-13 | Nytt glykolipid og medisin for autoimmunsykdom inneholdende det samme som aktiv ingrediens. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8367623B2 (no) |
| EP (1) | EP1437358B1 (no) |
| JP (1) | JP4064346B2 (no) |
| KR (1) | KR100880063B1 (no) |
| CN (1) | CN100439383C (no) |
| AT (1) | ATE342910T1 (no) |
| AU (1) | AU2002327097B2 (no) |
| BR (1) | BR0211968A (no) |
| CA (1) | CA2459482C (no) |
| DE (1) | DE60215530T2 (no) |
| DK (1) | DK1437358T3 (no) |
| ES (1) | ES2274080T3 (no) |
| HU (1) | HU229345B1 (no) |
| NO (1) | NO326398B1 (no) |
| WO (1) | WO2003016326A1 (no) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9809654B2 (en) | 2002-09-27 | 2017-11-07 | Vaccinex, Inc. | Targeted CD1d molecules |
| EP2343306B1 (en) | 2003-02-14 | 2018-04-04 | Japan as represented by President of National Center of Neurology and Psychiatry Ministry of Health | Glycolipid derivatives, process for production of the same, intermediates for synthesis thereof, and process for production of the intermediates |
| AU2005280163B2 (en) * | 2004-08-27 | 2011-11-24 | Albert Einstein College Of Medicine, Inc. | Ceramide derivatives as modulators of immunity and autoimmunity |
| KR101243577B1 (ko) | 2004-10-07 | 2013-03-20 | 아고스 쎄라퓨틱스, 인코포레이티드 | 성숙 수지상 세포 조성물 및 그의 배양 방법 |
| US8513008B2 (en) | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| US7923013B2 (en) | 2004-12-28 | 2011-04-12 | The Rockefeller University | Glycolipids and analogues thereof as antigens for NKT cells |
| EP1833489A4 (en) * | 2004-12-28 | 2011-08-03 | Univ Rockefeller | GLYCOLIPIDES AND ANALOGUE THEREOF AS ANTIGENS FOR NK-T CELLS |
| WO2006107097A1 (ja) * | 2005-04-01 | 2006-10-12 | Riken | 経鼻ワクチン |
| CA2613350A1 (en) * | 2005-07-01 | 2007-01-11 | Japan As Represented By President Of National Center Of Neurology And Ps Ychiatry | Glycolipid derivative and drug containing the same as active component |
| WO2007049819A1 (ja) * | 2005-10-28 | 2007-05-03 | Japan As Represented By President Of National Center Of Neurology And Psychiatry | Nkt細胞の機能を抑制する糖脂質誘導体を有効成分とする治療剤 |
| JP5126684B2 (ja) * | 2006-02-28 | 2013-01-23 | 独立行政法人理化学研究所 | 新規糖脂質及びその用途 |
| JP5564672B2 (ja) * | 2006-06-30 | 2014-07-30 | ザ スクリプス リサーチ インスティテュート | アジュバント及びその使用方法 |
| KR100868959B1 (ko) * | 2006-12-30 | 2008-11-17 | 재단법인서울대학교산학협력재단 | 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물 |
| EP2112930B1 (en) | 2007-02-21 | 2017-01-11 | Vaccinex, Inc. | Modulation of nkt cell activity with antigen-loaded cdid molecules |
| ES2574825T3 (es) * | 2007-10-12 | 2016-06-22 | Luigi Panza | Análogos de glicolípidos útiles como inmunoadyuvantes |
| KR20110137290A (ko) * | 2009-01-08 | 2011-12-22 | 알버트 아인슈타인 컬리지 오브 메디신 오브 예쉬바 유니버시티 | 세포벽 결합 세라미드 유사 당지질을 갖는 박테리아 백신 및 이의 용도 |
| US9371352B2 (en) | 2013-02-08 | 2016-06-21 | Vaccinex, Inc. | Modified glycolipids and methods of making and using the same |
| JP6202339B2 (ja) * | 2013-12-19 | 2017-09-27 | 国立研究開発法人国立精神・神経医療研究センター | ＧＭ−ＣＳＦ産生Ｔ細胞制御剤、及びＴｈ１／Ｔｈ２免疫バランス調節剤 |
| US10022401B2 (en) | 2014-02-26 | 2018-07-17 | National University Corporation Hokkaido University | Pharmaceutical containing dendritic cells, and method for producing same |
| CN114096260A (zh) | 2019-07-12 | 2022-02-25 | 国立大学法人九州大学 | 心肌收缩改善治疗法和心肌细胞死亡抑制法的开发 |
| US20230405033A1 (en) * | 2020-11-06 | 2023-12-21 | National Center Of Neurology And Psychiatry | Therapeutic Agent for Progressive Disease Caused by Increase in Eomes-Positive CD4-Positive T Cells |
| WO2022187141A1 (en) | 2021-03-01 | 2022-09-09 | Deciduous Therapeutics | Compounds for activating invariant natural killer t-cells and methods of use in eliminating inflammatory senescent cells |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5827828A (ja) * | 1981-08-11 | 1983-02-18 | Mitsubishi Electric Corp | 燃料噴射装置 |
| DK84691D0 (da) * | 1991-05-07 | 1991-05-07 | Karsten Buschard | Visse glycolipider og specifikke catchere for disse til anvendelse ved profylaxe eller terapi af diabetes, og/eller dermed forbundne komplikationer samt anvendelse af saadanne glycolipider til detektion af oe-celle-antistoffer (ica) i et individ og anvendelse af saadanne catchere til detektion af langerhans-oe-celler i pancreas-praeparater |
| US5936076A (en) * | 1991-08-29 | 1999-08-10 | Kirin Beer Kabushiki Kaisha | αgalactosylceramide derivatives |
| JPH0559081A (ja) | 1991-08-29 | 1993-03-09 | Kirin Brewery Co Ltd | 新規スフインゴ糖脂質、その製造法および使用 |
| GB9207182D0 (en) * | 1992-04-01 | 1992-05-13 | Enzymatix Ltd | Glycolipids and their preparation |
| TW261533B (no) * | 1992-07-16 | 1995-11-01 | Kirin Brewery | |
| CA2142153A1 (en) * | 1994-03-04 | 1995-09-05 | Jacques Banville | Sulfated .beta.-glycolipid derivatives as cell adhesion inhibitors |
| US5861520A (en) * | 1994-05-31 | 1999-01-19 | Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) | Glycolipid analogs |
| DE19602108A1 (de) * | 1996-01-22 | 1997-07-24 | Beiersdorf Ag | Gegen Bakterien, Parasiten, Protozoen, Mycota und Viren wirksame Substanzen |
| JP4451933B2 (ja) * | 1996-12-27 | 2010-04-14 | 住友化学株式会社 | 遺伝子操作による植物へのｐｐｏ阻害性除草剤耐性付与法 |
| ES2235324T3 (es) * | 1997-04-10 | 2005-07-01 | Kirin Beer Kabushiki Kaisha | Empleo de a-glicosilceramidas para la obtencion de un agente terapeutico para enfermedades autoinmunes. |
| US6589940B1 (en) * | 1997-06-06 | 2003-07-08 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| TW575420B (en) * | 1997-09-22 | 2004-02-11 | Kirin Brewery | Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides |
| US7273711B1 (en) * | 1998-12-02 | 2007-09-25 | The Regents Of The University Of California | Diagnosis of human glycosylation disorders |
| JP2002284692A (ja) * | 2001-03-26 | 2002-10-03 | Kirin Brewery Co Ltd | α−グリコシルセラミドによる移植片対宿主病（ＧＶＨＤ）の抑制 |
-
2002
- 2002-08-14 DK DK02760637T patent/DK1437358T3/da active
- 2002-08-14 WO PCT/JP2002/008280 patent/WO2003016326A1/ja not_active Ceased
- 2002-08-14 KR KR1020047002291A patent/KR100880063B1/ko not_active Expired - Lifetime
- 2002-08-14 AU AU2002327097A patent/AU2002327097B2/en not_active Expired
- 2002-08-14 CN CNB028203615A patent/CN100439383C/zh not_active Expired - Lifetime
- 2002-08-14 HU HU0500127A patent/HU229345B1/hu unknown
- 2002-08-14 US US10/486,948 patent/US8367623B2/en not_active Expired - Fee Related
- 2002-08-14 AT AT02760637T patent/ATE342910T1/de not_active IP Right Cessation
- 2002-08-14 ES ES02760637T patent/ES2274080T3/es not_active Expired - Lifetime
- 2002-08-14 EP EP02760637A patent/EP1437358B1/en not_active Expired - Lifetime
- 2002-08-14 BR BR0211968-4A patent/BR0211968A/pt not_active IP Right Cessation
- 2002-08-14 DE DE60215530T patent/DE60215530T2/de not_active Expired - Lifetime
- 2002-08-14 CA CA2459482A patent/CA2459482C/en not_active Expired - Lifetime
- 2002-08-14 JP JP2003521248A patent/JP4064346B2/ja not_active Expired - Lifetime
-
2004
- 2004-02-13 NO NO20040653A patent/NO326398B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60215530T2 (de) | 2007-05-31 |
| JP4064346B2 (ja) | 2008-03-19 |
| CN1568328A (zh) | 2005-01-19 |
| JPWO2003016326A1 (ja) | 2004-12-02 |
| DE60215530D1 (de) | 2006-11-30 |
| KR100880063B1 (ko) | 2009-01-22 |
| ES2274080T3 (es) | 2007-05-16 |
| AU2002327097B2 (en) | 2007-05-24 |
| WO2003016326A1 (fr) | 2003-02-27 |
| HU229345B1 (en) | 2013-11-28 |
| KR20040039287A (ko) | 2004-05-10 |
| BR0211968A (pt) | 2004-09-28 |
| EP1437358A4 (en) | 2004-11-24 |
| CA2459482A1 (en) | 2003-02-27 |
| EP1437358A1 (en) | 2004-07-14 |
| US8367623B2 (en) | 2013-02-05 |
| NO326398B1 (no) | 2008-11-24 |
| CA2459482C (en) | 2010-09-28 |
| DK1437358T3 (da) | 2007-02-05 |
| HUP0500127A3 (en) | 2009-12-28 |
| HUP0500127A2 (en) | 2006-09-28 |
| ATE342910T1 (de) | 2006-11-15 |
| CN100439383C (zh) | 2008-12-03 |
| EP1437358B1 (en) | 2006-10-18 |
| US20060148723A1 (en) | 2006-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |