NO20035791L - Nye derivater av oksazolidinoner som antibakterielle midler - Google Patents
Nye derivater av oksazolidinoner som antibakterielle midlerInfo
- Publication number
- NO20035791L NO20035791L NO20035791A NO20035791A NO20035791L NO 20035791 L NO20035791 L NO 20035791L NO 20035791 A NO20035791 A NO 20035791A NO 20035791 A NO20035791 A NO 20035791A NO 20035791 L NO20035791 L NO 20035791L
- Authority
- NO
- Norway
- Prior art keywords
- oxazolidinones
- antibacterial agents
- new derivatives
- derivatives
- medicament
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940124307 fluoroquinolone Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200101559A ES2186550B2 (es) | 2001-06-27 | 2001-06-27 | Nuevos derivados de oxazolidinonas como antibacterianos. |
| PCT/IB2002/002408 WO2003002560A1 (en) | 2001-06-27 | 2002-06-24 | New derivatives of oxazolidinones as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20035791L true NO20035791L (no) | 2004-02-19 |
Family
ID=8498288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20035791A NO20035791L (no) | 2001-06-27 | 2003-12-22 | Nye derivater av oksazolidinoner som antibakterielle midler |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20040147545A1 (es) |
| EP (1) | EP1401834A1 (es) |
| JP (1) | JP2004521147A (es) |
| KR (1) | KR20040030712A (es) |
| CN (1) | CN1520412A (es) |
| AP (1) | AP2003002942A0 (es) |
| AR (1) | AR035254A1 (es) |
| BG (1) | BG108498A (es) |
| BR (1) | BR0210667A (es) |
| CA (1) | CA2450982A1 (es) |
| CO (1) | CO5540387A2 (es) |
| CR (1) | CR7195A (es) |
| CZ (1) | CZ2004101A3 (es) |
| EA (1) | EA200400086A1 (es) |
| EE (1) | EE200400004A (es) |
| ES (1) | ES2186550B2 (es) |
| HR (1) | HRP20031063A2 (es) |
| HU (1) | HUP0400370A2 (es) |
| IL (1) | IL159434A0 (es) |
| IS (1) | IS7088A (es) |
| MA (1) | MA27046A1 (es) |
| MX (1) | MXPA04000185A (es) |
| NO (1) | NO20035791L (es) |
| NZ (1) | NZ530206A (es) |
| OA (1) | OA12639A (es) |
| PE (1) | PE20030134A1 (es) |
| PL (1) | PL365476A1 (es) |
| SK (1) | SK572004A3 (es) |
| WO (1) | WO2003002560A1 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003031443A1 (en) * | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
| EP1620098B1 (en) * | 2003-04-30 | 2008-06-11 | Morphochem Aktiengesellschaft Für Kombinatorische Chemie | Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections |
| DE10340485B4 (de) | 2003-09-03 | 2015-05-13 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden |
| US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
| WO2005051933A1 (en) * | 2003-11-28 | 2005-06-09 | Ranbaxy Laboratories Limited | An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby |
| US8158797B2 (en) | 2003-12-18 | 2012-04-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| AU2004299278C9 (en) * | 2003-12-18 | 2013-10-24 | Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| EP1557416A1 (en) * | 2004-01-23 | 2005-07-27 | Morphochem Aktiengesellschaft Für Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| US20060105941A1 (en) * | 2004-11-12 | 2006-05-18 | Allergan, Inc. | Mixed antibiotic codrugs |
| US8148362B2 (en) | 2006-03-31 | 2012-04-03 | Research Foundation Itsuu Laboratory | Compound having heterocyclic ring |
| WO2009044777A1 (ja) | 2007-10-02 | 2009-04-09 | Research Foundation Itsuu Laboratory | ７員ヘテロ環を有するオキサゾリジノン誘導体 |
| JP4819980B2 (ja) * | 2008-05-09 | 2011-11-24 | アクテリオン ファーマシューティカルズ リミテッド | 細菌性腸管疾患の治療のための５−ヒドロキシメチル−オキサゾリジン−２−オン誘導体 |
| AU2014273471B2 (en) | 2013-05-28 | 2019-10-03 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Combination therapy comprising oxazolidinone-quinolones for use in treating bacterial infections |
| PT3003289T (pt) | 2013-05-28 | 2019-06-04 | Morphochem Gmbh | Administração de antibacterianos híbridos de oxazolidinona-quinolona |
| CN107286111B (zh) * | 2016-03-30 | 2020-06-19 | 广东赛法洛药业有限公司 | 一种噁唑烷酮化合物的制备方法 |
| CN107286182A (zh) * | 2016-04-12 | 2017-10-24 | 李靖 | 新型噁唑烷酮‑氟喹诺酮衍生物及用途 |
| US10087171B2 (en) | 2016-12-19 | 2018-10-02 | Actelion Pharmaceuticals Ltd | Crystalline forms of cadazolid |
| GB201708606D0 (en) * | 2017-05-30 | 2017-07-12 | King S College London | Antibiotic resistance breakers |
| JP7390728B2 (ja) * | 2017-11-29 | 2023-12-04 | バグワークス・リサーチ・インコーポレイテッド | 抗菌複素環式化合物及びそれらの合成 |
| CN111087409B (zh) * | 2018-10-24 | 2021-06-08 | 江阴安博生物医药有限公司 | 一种喹诺酮类化合物及其制备方法和应用 |
| CN112940038A (zh) * | 2019-12-11 | 2021-06-11 | 华创合成制药股份有限公司 | 新型噁唑烷酮类化合物及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE444566B (sv) * | 1977-09-20 | 1986-04-21 | Bellon Labor Sa Roger | 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav |
| EP0390215B1 (en) * | 1989-03-30 | 1995-06-07 | Wakunaga Seiyaku Kabushiki Kaisha | Quinolone derivatives and salts thereof, preparation process es thereof, and antibacterial agents containing the same |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| CN1068325C (zh) * | 1994-10-26 | 2001-07-11 | 法玛西雅厄普约翰美国公司 | 苯基噁唑烷酮抗菌剂 |
| AU713704B2 (en) * | 1996-01-31 | 1999-12-09 | Sankyo Company Limited | Agents for the treatment and prevention of aids |
| CZ298060B6 (cs) * | 1996-04-11 | 2007-06-06 | Pharmacia & Upjohn Company | Zpusob prípravy oxazolidinonu |
| GB9614236D0 (en) * | 1996-07-06 | 1996-09-04 | Zeneca Ltd | Chemical compounds |
-
2001
- 2001-06-27 ES ES200101559A patent/ES2186550B2/es not_active Expired - Fee Related
-
2002
- 2002-06-24 CZ CZ2004101A patent/CZ2004101A3/cs unknown
- 2002-06-24 EP EP02738497A patent/EP1401834A1/en not_active Withdrawn
- 2002-06-24 CA CA002450982A patent/CA2450982A1/en not_active Abandoned
- 2002-06-24 MX MXPA04000185A patent/MXPA04000185A/es unknown
- 2002-06-24 OA OA1200300345A patent/OA12639A/en unknown
- 2002-06-24 US US10/469,283 patent/US20040147545A1/en not_active Abandoned
- 2002-06-24 AP APAP/P/2003/002942A patent/AP2003002942A0/en unknown
- 2002-06-24 SK SK57-2004A patent/SK572004A3/sk unknown
- 2002-06-24 PL PL02365476A patent/PL365476A1/xx not_active Application Discontinuation
- 2002-06-24 EE EEP200400004A patent/EE200400004A/xx unknown
- 2002-06-24 HR HR20031063A patent/HRP20031063A2/xx not_active Application Discontinuation
- 2002-06-24 HU HU0400370A patent/HUP0400370A2/hu unknown
- 2002-06-24 NZ NZ530206A patent/NZ530206A/en unknown
- 2002-06-24 IL IL15943402A patent/IL159434A0/xx unknown
- 2002-06-24 CN CNA028128524A patent/CN1520412A/zh active Pending
- 2002-06-24 JP JP2003508941A patent/JP2004521147A/ja active Pending
- 2002-06-24 KR KR10-2003-7017038A patent/KR20040030712A/ko not_active Withdrawn
- 2002-06-24 BR BR0210667-1A patent/BR0210667A/pt not_active Application Discontinuation
- 2002-06-24 WO PCT/IB2002/002408 patent/WO2003002560A1/en not_active Ceased
- 2002-06-24 EA EA200400086A patent/EA200400086A1/ru unknown
- 2002-06-26 PE PE2002000572A patent/PE20030134A1/es not_active Application Discontinuation
- 2002-06-26 AR ARP020102399A patent/AR035254A1/es not_active Application Discontinuation
-
2003
- 2003-12-10 CR CR7195A patent/CR7195A/es not_active Application Discontinuation
- 2003-12-22 IS IS7088A patent/IS7088A/is unknown
- 2003-12-22 NO NO20035791A patent/NO20035791L/no not_active Application Discontinuation
- 2003-12-22 BG BG108498A patent/BG108498A/xx unknown
- 2003-12-23 MA MA27460A patent/MA27046A1/fr unknown
- 2003-12-26 CO CO03112619A patent/CO5540387A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MA27046A1 (fr) | 2004-12-20 |
| IS7088A (is) | 2003-12-22 |
| OA12639A (en) | 2006-06-15 |
| ES2186550A1 (es) | 2003-05-01 |
| CR7195A (es) | 2004-03-05 |
| ES2186550B2 (es) | 2003-11-16 |
| MXPA04000185A (es) | 2004-03-18 |
| JP2004521147A (ja) | 2004-07-15 |
| HRP20031063A2 (en) | 2004-04-30 |
| BG108498A (en) | 2005-03-31 |
| CZ2004101A3 (cs) | 2004-07-14 |
| BR0210667A (pt) | 2004-10-05 |
| CN1520412A (zh) | 2004-08-11 |
| NZ530206A (en) | 2005-07-29 |
| WO2003002560A1 (en) | 2003-01-09 |
| HUP0400370A2 (hu) | 2004-08-30 |
| IL159434A0 (en) | 2004-06-01 |
| EA200400086A1 (ru) | 2004-06-24 |
| AP2003002942A0 (en) | 2003-12-24 |
| CO5540387A2 (es) | 2005-07-29 |
| EE200400004A (et) | 2004-02-16 |
| PL365476A1 (en) | 2005-01-10 |
| EP1401834A1 (en) | 2004-03-31 |
| US20040147545A1 (en) | 2004-07-29 |
| PE20030134A1 (es) | 2003-04-04 |
| KR20040030712A (ko) | 2004-04-09 |
| CA2450982A1 (en) | 2003-01-09 |
| AR035254A1 (es) | 2004-05-05 |
| SK572004A3 (en) | 2004-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |