NO20020380L - Nye cytokrom P450-monooksygenaser og deres anvendelse for oksydasjon av organiske forbindelser - Google Patents
Nye cytokrom P450-monooksygenaser og deres anvendelse for oksydasjon av organiske forbindelserInfo
- Publication number
- NO20020380L NO20020380L NO20020380A NO20020380A NO20020380L NO 20020380 L NO20020380 L NO 20020380L NO 20020380 A NO20020380 A NO 20020380A NO 20020380 A NO20020380 A NO 20020380A NO 20020380 L NO20020380 L NO 20020380L
- Authority
- NO
- Norway
- Prior art keywords
- oxygenases
- mono
- oxidation
- organic compounds
- methods
- Prior art date
Links
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 title abstract 2
- 101710198130 NADPH-cytochrome P450 reductase Proteins 0.000 title abstract 2
- 150000002894 organic compounds Chemical class 0.000 title 1
- 230000003647 oxidation Effects 0.000 title 1
- 238000007254 oxidation reaction Methods 0.000 title 1
- CRDNMYFJWFXOCH-YPKPFQOOSA-N (3z)-3-(3-oxo-1h-indol-2-ylidene)-1h-indol-2-one Chemical compound N/1C2=CC=CC=C2C(=O)C\1=C1/C2=CC=CC=C2NC1=O CRDNMYFJWFXOCH-YPKPFQOOSA-N 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- CRDNMYFJWFXOCH-BUHFOSPRSA-N Couroupitine B Natural products N\1C2=CC=CC=C2C(=O)C/1=C1/C2=CC=CC=C2NC1=O CRDNMYFJWFXOCH-BUHFOSPRSA-N 0.000 abstract 1
- 235000000177 Indigofera tinctoria Nutrition 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 229940097275 indigo Drugs 0.000 abstract 1
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 abstract 1
- CRDNMYFJWFXOCH-UHFFFAOYSA-N isoindigotin Natural products N1C2=CC=CC=C2C(=O)C1=C1C2=CC=CC=C2NC1=O CRDNMYFJWFXOCH-UHFFFAOYSA-N 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
- C12P17/165—Heterorings having nitrogen atoms as the only ring heteroatoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90245—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19935115A DE19935115A1 (de) | 1999-07-27 | 1999-07-27 | Elektronendonorsystem für Enzyme |
| DE19955605A DE19955605A1 (de) | 1999-11-18 | 1999-11-18 | Neue Cytochrom P450-Monoxygenasen und deren Verwendung zur Oxidation N-heterocyclischer Aromaten |
| DE10014085A DE10014085A1 (de) | 2000-03-22 | 2000-03-22 | Neue Cytochrom P450-Monooxygenasen und deren Verwendung zur Oxidation von organischen Verbindungen |
| PCT/EP2000/007253 WO2001007630A1 (de) | 1999-07-27 | 2000-07-27 | Neue cytochrom p450-monooxygenasen und deren verwendung zur oxidation von organischen verbindungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20020380D0 NO20020380D0 (no) | 2002-01-24 |
| NO20020380L true NO20020380L (no) | 2002-03-22 |
Family
ID=27213745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20020380A NO20020380L (no) | 1999-07-27 | 2002-01-24 | Nye cytokrom P450-monooksygenaser og deres anvendelse for oksydasjon av organiske forbindelser |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7960155B1 (no) |
| EP (1) | EP1196605B1 (no) |
| JP (1) | JP4791664B2 (no) |
| KR (2) | KR20070041792A (no) |
| CN (1) | CN1183252C (no) |
| AT (1) | ATE409232T1 (no) |
| AU (1) | AU780694B2 (no) |
| BR (1) | BR0012772B1 (no) |
| CA (1) | CA2380186C (no) |
| DE (1) | DE50015373D1 (no) |
| EE (1) | EE200200048A (no) |
| ES (1) | ES2311470T3 (no) |
| HU (1) | HU229450B1 (no) |
| IL (2) | IL147580A0 (no) |
| MY (1) | MY126592A (no) |
| NO (1) | NO20020380L (no) |
| UA (1) | UA76701C2 (no) |
| WO (1) | WO2001007630A1 (no) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003505066A (ja) * | 1999-07-27 | 2003-02-12 | ビーエーエスエフ アクチェンゲゼルシャフト | 酵素の電子供与体系ならびに基質の生化学的変換におけるその使用 |
| CA2418155A1 (en) | 2000-07-18 | 2002-01-24 | National Research Council Of Canada | Cloning, sequencing and expression of a comamonas cyclopentanone 1,2-monooxygenase-encoding gene in escherichia coli |
| DE10051175A1 (de) | 2000-10-16 | 2002-05-02 | Basf Ag | Cytochrom P450 Monoxygenasen aus thermophilen Bakterien |
| DE10321082A1 (de) * | 2003-05-09 | 2004-11-25 | Basf Ag | Verfahren zur Herstellung eines Hydroxylierungskatalysators und seine Verwendung |
| WO2006009334A1 (en) * | 2004-07-23 | 2006-01-26 | Genechem Inc. | Cytochrome p450 enzyme and the gene encoding the same |
| DE102004042102A1 (de) * | 2004-08-30 | 2006-03-09 | GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) | Verfahren zur regio-selektiven Oxidation |
| US8715988B2 (en) * | 2005-03-28 | 2014-05-06 | California Institute Of Technology | Alkane oxidation by modified hydroxylases |
| CN100400652C (zh) * | 2005-07-21 | 2008-07-09 | 南开大学 | 高效降解芘基因工程菌及其构建 |
| CN100429314C (zh) * | 2006-04-18 | 2008-10-29 | 浙江大学 | 能催化吲哚生成靛蓝的质粒pET28a(+)-P450 BM3-gdh0310、制备方法及其用途 |
| JP5186497B2 (ja) * | 2006-07-27 | 2013-04-17 | チバ ホールディング インコーポレーテッド | ポリオレフィンの生体触媒的な親水化 |
| GB0719620D0 (en) * | 2007-10-08 | 2007-11-14 | Isis Innovation | Mutant Enzymes |
| KR100975404B1 (ko) * | 2008-02-28 | 2010-08-11 | 주식회사 종합건축사사무소근정 | 블록담장용 지주 및 이의 시공방법 |
| CN101333521B (zh) * | 2008-04-25 | 2010-12-15 | 浙江大学 | 细胞色素p450bm-3d168w变体酶以及应用其制备靛玉红的方法 |
| DE102008054918A1 (de) * | 2008-12-18 | 2010-07-01 | Evonik Degussa Gmbh | Verfahren zur enzymatischen Umsetzung von Alkanen |
| CN101580821B (zh) * | 2009-01-19 | 2011-04-27 | 广东省微生物研究所 | 用于制备抗癌药物靛玉红的2-萘酸单加氧酶 |
| EP2426198A1 (en) | 2010-09-03 | 2012-03-07 | B.R.A.I.N. Biotechnology Research And Information Network AG | Cytochrome P450 monooxygenase variants |
| CN102154234A (zh) * | 2011-01-18 | 2011-08-17 | 浙江大学 | 具有多环芳烃羟化酶活性的细胞色素p450单加氧酶 |
| CN103146596A (zh) * | 2012-12-14 | 2013-06-12 | 徐州工程学院 | 一种生产靛蓝色素的专用菌株 |
| WO2014100251A1 (en) * | 2012-12-18 | 2014-06-26 | California Institute Of Technology | A cytochrome p450-based biodesulfurization pathway |
| CN110462048A (zh) | 2017-04-07 | 2019-11-15 | 帝斯曼知识产权资产管理有限公司 | 异佛尔酮的区域选择性羟基化和朝向氧代异佛尔酮的进一步转换 |
| US10975243B2 (en) | 2018-12-28 | 2021-04-13 | Industrial Technology Research Institute | Genetically modified microorganism and method for producing indigo dye |
| EP3858986A1 (en) | 2020-02-03 | 2021-08-04 | Bayer Aktiengesellschaft | P450 bm3 monooxygenase variants for c19-hydroxylation of steroids |
| US11345818B1 (en) | 2020-12-29 | 2022-05-31 | Industrial Technology Research Institute | Dye for fiber and dyeing method |
| JPWO2024004921A1 (no) * | 2022-06-27 | 2024-01-04 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9422205D0 (en) | 1994-11-03 | 1994-12-21 | British Gas Plc | Enzyme mutant and method |
| DE19507546C2 (de) * | 1995-03-03 | 2001-05-03 | Max Delbrueck Centrum | Verfahren zur regioselektiven Hydroxylierung von langkettigen Alkanen, Fettsäuren und anderen Alkylverbindungen |
| US5691171A (en) * | 1995-10-23 | 1997-11-25 | Board Of Trustees Operating Michigan State University | Method for production of indigo and indirubin dyes |
| CN1212015A (zh) * | 1995-11-01 | 1999-03-24 | Bg公开有限公司 | 突变单加氧酶细胞色素P450cam |
| AU5347999A (en) * | 1998-08-12 | 2000-03-06 | Maxygen, Inc. | Dna shuffling of monooxygenase genes for production of industrial chemicals |
| GB9825421D0 (en) * | 1998-11-19 | 1999-01-13 | Isis Innovation | Process for oxidising terpenes |
| JP2003505066A (ja) * | 1999-07-27 | 2003-02-12 | ビーエーエスエフ アクチェンゲゼルシャフト | 酵素の電子供与体系ならびに基質の生化学的変換におけるその使用 |
-
2000
- 2000-07-26 MY MYPI20003409 patent/MY126592A/en unknown
- 2000-07-27 WO PCT/EP2000/007253 patent/WO2001007630A1/de not_active Ceased
- 2000-07-27 EP EP00956319A patent/EP1196605B1/de not_active Expired - Lifetime
- 2000-07-27 AU AU68307/00A patent/AU780694B2/en not_active Ceased
- 2000-07-27 JP JP2001512896A patent/JP4791664B2/ja not_active Expired - Fee Related
- 2000-07-27 EE EEP200200048A patent/EE200200048A/xx unknown
- 2000-07-27 US US10/031,146 patent/US7960155B1/en not_active Expired - Fee Related
- 2000-07-27 DE DE50015373T patent/DE50015373D1/de not_active Expired - Lifetime
- 2000-07-27 IL IL14758000A patent/IL147580A0/xx unknown
- 2000-07-27 CA CA2380186A patent/CA2380186C/en not_active Expired - Lifetime
- 2000-07-27 CN CNB008109184A patent/CN1183252C/zh not_active Expired - Fee Related
- 2000-07-27 ES ES00956319T patent/ES2311470T3/es not_active Expired - Lifetime
- 2000-07-27 KR KR1020077007332A patent/KR20070041792A/ko not_active Ceased
- 2000-07-27 KR KR1020027001132A patent/KR100740368B1/ko not_active Expired - Fee Related
- 2000-07-27 UA UA2002021606A patent/UA76701C2/uk unknown
- 2000-07-27 BR BRPI0012772-8A patent/BR0012772B1/pt not_active IP Right Cessation
- 2000-07-27 HU HU0202074A patent/HU229450B1/hu not_active IP Right Cessation
- 2000-07-27 AT AT00956319T patent/ATE409232T1/de active
-
2002
- 2002-01-10 IL IL147580A patent/IL147580A/en active IP Right Grant
- 2002-01-24 NO NO20020380A patent/NO20020380L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1196605A1 (de) | 2002-04-17 |
| KR20020016924A (ko) | 2002-03-06 |
| MY126592A (en) | 2006-10-31 |
| IL147580A (en) | 2013-12-31 |
| US7960155B1 (en) | 2011-06-14 |
| HUP0202074A3 (en) | 2010-01-28 |
| HUP0202074A2 (en) | 2002-09-28 |
| JP2003521889A (ja) | 2003-07-22 |
| EE200200048A (et) | 2003-04-15 |
| ATE409232T1 (de) | 2008-10-15 |
| BR0012772B1 (pt) | 2013-05-28 |
| NO20020380D0 (no) | 2002-01-24 |
| CA2380186A1 (en) | 2001-02-01 |
| CN1183252C (zh) | 2005-01-05 |
| HU229450B1 (hu) | 2013-12-30 |
| AU780694B2 (en) | 2005-04-14 |
| ES2311470T3 (es) | 2009-02-16 |
| AU6830700A (en) | 2001-02-13 |
| WO2001007630A1 (de) | 2001-02-01 |
| UA76701C2 (uk) | 2006-09-15 |
| CN1365393A (zh) | 2002-08-21 |
| KR100740368B1 (ko) | 2007-07-16 |
| BR0012772A (pt) | 2002-04-02 |
| CA2380186C (en) | 2012-03-13 |
| DE50015373D1 (de) | 2008-11-06 |
| JP4791664B2 (ja) | 2011-10-12 |
| KR20070041792A (ko) | 2007-04-19 |
| IL147580A0 (en) | 2002-08-14 |
| EP1196605B1 (de) | 2008-09-24 |
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